Clinical trials: Malignant Neoplasm of Female Breast
Breast Cancer Female
Fertility Changes Due to Cancer: an Investigation of Meaning, Psychological Distress, and Psychologi
Establish the relationship between meaning and psychological distress in young women with breast cancer who experienced reproductive concerns due to cancer diagnosis and treatment and their partners.
- Trial name
- NCT05245162
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Breast Neoplasm Female
PILATES METHOD ON THE UPPER LIMBS FUNCTIONALITY
INTRODUCTION: Breast cancer is one of the pathologies affecting women worldwide, with a high mortality rate of 14,206 per 100,000 women per year.
- Trial name
- NCT03826979
- Testing
- Pliates method treatment
- Where
- Brazil
- Volunteers
- 22 people
- Sponsor
- Universidade Metodista de Piracicaba
Breast Cancer Female, Psychological Distress
The Breast Cancer Survivors and Partners Online Research Together (SUPORT) Project
Many breast cancer survivors (estimated 70% in some studies) experience clinically significant depression and/or anxiety in the months and years after finishing cancer treatments.
- Trial name
- NCT05676255
- Testing
- Cognitively-Based Compassion Training for Survivors, Cognitively-Based Compassion Training for Dyads, Health Education
- Where
- United States
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Breast Cancer Female, Mammography Screening
Investigating Barriers for Decision Making in a Danish Breast Cancer Screening Context
The aim is to investigate potential barriers to informed decision making in a breast cancer screening context. This is a necessary step prior to developing and investigating improved information or decision aids in a Danish…
- Conditions
- Breast Cancer Female, Mammography Screening, Decision Making, Information Seeking Behavior
- Trial name
- NCT05444725
- Testing
- Stage of Decision Making, Choice framing, Opportunity Framing
- Where
- Denmark
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Breast Cancer Female, Mastectomy
Opting for Breast Reconstruction After Mastectomy or Not: Search for Influencing Factors
The purpose of this study is to investigate the factors influencing the decision about breast reconstruction after breast amputation for breast cancer.
- Conditions
- Breast Cancer Female, Mastectomy, Breast Reconstruction
- Trial name
- NCT03039348
- Testing
- semi-structured interview using a questionnaire
- Volunteers
- 100 people
- Sponsor
- Universitair Ziekenhuis Brussel
Triple Negative Breast Cancer, Endometrial Cancer
ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma
Background: The new drug ONC201 have been shown to kill breast cancer and endometrial cancer cells in the laboratory. The exact mechanism of action is not completely clear yet, but the ONC201 destroys the mitochondria inside the…
- Conditions
- Triple Negative Breast Cancer, Endometrial Cancer, Hormone Receptor Positive, HER2 Negative Breast Cancer
- Trial name
- NCT03394027
- Testing
- ONC201
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Cancer Institute (NCI)
Breast Neoplasm, Female
KNUCH CadAI-B-1(KCB-1)
The CadAI-B (Computer Aided Design Artificial Intelligence-Breast) system is a real-time AI diagnostic tool for breast ultrasound.
- Trial name
- NCT06622967
- Testing
- CadAI-B
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- JeeYeon Lee
Breast Cancer Female
Early Detection of Cardiovascular Changes After Radiotherapy for Breast Cancer
Breast cancer (BC) radiotherapy leads to coincidental radiation of the heart, resulting in increased risk of a variety of heart diseases.
- Trial name
- EARLY-HEART (NCT03297346)
- Testing
- Cardiac imaging and circulating biomarkers
- Where
- 5 sites in France, Germany and 3 more
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- French Nuclear Safety and Radiation Protection Authority (ASNR)
Breast Neoplasm Malignant Primary
A Prospective Cohort With Patient Navigation as an Intervention for Breast Cancer Patients
The objective of this observational study is to introduce a patient navigation system within the breast cancer unit at Hospital Central de Maputo (MOZ) and gather data to assess the efficacy of patient navigation in enhancing…
- Trial name
- NAVIMOZ (NCT06257888)
- Testing
- patient navigation
- Where
- Mozambique
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Renato Cagnacci Neto
Metastatic Cancer, Metastatic Breast Cancer
A Phase 1 First-In-Human Study of the Anti-CD73 IPH5301 Alone or in Combination With Chemotherapy and Trastuzumab in Patients With Advanced Solid Tumors
CHANCES-IPC 2021-008 is First In Human, Phase I, multicenter, European study evaluating an anti-CD73, IPH5301 in advanced and/or metastatic cancer.
- Conditions
- Metastatic Cancer, Metastatic Breast Cancer, Metastatic Pancreatic Cancer, Metastatic Gastric Cancer
- Trial name
- CHANCES (NCT05143970)
- Testing
- IPH5301 ALONE OR IN COMBINATION WITH CHEMOTHERAPY AND TRASTUZUMAB
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Institut Paoli-Calmettes
Breast Cancer Female, Overweight and Obesity
Lifestyle Behavioural Intervention on Breast Cancer Survivors for the Treatment of Overweight/Obesity.
The goal of this clinical trial is to compare a behavioural lifestyle intervention program (BL) to usual care (UC) in breast cancer survivors. The main questions it aims to answer are: 1.
- Trial name
- Nutri-Life (NCT06577545)
- Testing
- Behavioural Lifestyle (BL)
- Where
- Greece
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Symptom Distress During Breast Cancer Treatment
Trajectory Analysis of Symptom Distress and Cancer-related Fatigue After Adjuvant Chemotherapy in Breast Cancer Female
When receiving adjuvant chemotherapy, a variety of symptoms will appear and it is very painful. These symptoms occur at the same time and are related to each other.
- Trial name
- NCT04911699
- Testing
- breast adenocarcinoma receiving chemotherapy, Control-for
- Volunteers
- 120 people
- Sponsor
- Taipei Medical University
Cancer
Study of Previously Collected and Stored Tissue Samples From Patients Previously Enrolled in a Completed National Cancer Institute Clinical Trial
RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00904514
- Testing
- gene expression analysis, microarray analysis, mutation analysis
- Volunteers
- 241 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Breast Cancer Female
Assessing the Clinical Utility of Adding Pentoxifylline to Neoadjuvant Chemotherapy Protocols in Breast Cancer Patients"
Breast cancer, a leading cause of cancer-related mortality in women worldwide, has spurred the investigation of novel therapeutic approaches.
- Trial name
- NCT06176339
- Testing
- Pentoxifylline Oral Tablet
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Breast Cancer Female
EMDR Psychotherapy for Anxious-depressive Symptoms in Breast Cancer Patient
The study will consist in an evaluation of the EMDR (Eye Movement Desensitization and Reprocessing) psychotherapy in the context on invasive primitive breast cancer.
- Trial name
- PSYCANCER (NCT03898453)
- Testing
- EMDR psychotherapy, support psychotherapy
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Advanced Breast Carcinoma, Advanced Malignant Solid Neoplasm
SMMART Adaptive Clinical Treatment (ACT) Trial
SMMART-ACT is a feasibility pilot study to determine if testing samples from a participant's cancer using a precision medicine approach can be used to identify specific drugs or drug combinations that can help control their…
- Conditions
- Advanced Breast Carcinoma, Advanced Malignant Solid Neoplasm, Advanced Ovarian Carcinoma, Advanced Pancreatic Carcinoma
- Trial name
- NCT05238831
- Testing
- Alectinib, Alpelisib, Anastrozole
- Sponsor
- OHSU Knight Cancer Institute
Breast Cancer Female
Evaluation of the Potential Impact of an Artificial Intelligence Solution in Second Reading of Organized Screening.
Based on data from a series of patients who underwent screening mammography with a "normal" or "benign" first-reading result. The main objective of the study is to evaluate the possibilities of subtracting from the second reading…
- Trial name
- ELIAS (NCT06479772)
- Where
- France
- Volunteers
- 55,589 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Breast Cancer Female, Stage I Breast Cancer
Living Well After Breast Surgery
Decision making about whether to have breast reconstruction after mastectomy can be difficult, and previous studies have found that many women are not well informed about their options.
- Conditions
- Breast Cancer Female, Stage I Breast Cancer, Stage II Breast Cancer, Stage III Breast Cancer
- Trial name
- NCT03834532
- Testing
- Breast reconstruction decision aid, Educational website
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Texas at Austin
Breast Cancer Female, Breast Reconstruction
Evaluation of the Clinical Effectiveness and Safety of Acellular Dermal Matrix(SC DERM® Recon) in Breast Reconstruction
This study is a multicenter, open-label study with both prospective and retrospective components, enrolling up to 120 subjects undergoing breast reconstruction using acellular dermal matrix (ADM).
- Trial name
- SCderm (NCT06555692)
- Testing
- Transplant acellular dermal matrix(ADM)
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- DOF Inc.
Cancer, Breast Cancer
Genomic Investigation of Unusual Responders
Studies have shown that tumors from the same patient may respond very differently to the same therapeutic agents. This study aims to investigate the genetic basis of tumors that respond abnormally well or poorly to therapeutic…
- Conditions
- Cancer, Breast Cancer, Non-small Cell Lung Cancer, Colorectal Cancer
- Trial name
- GENIUS (NCT03740503)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto