Clinical trials: Malignant Neoplasm of Female Breast
Breast Cancer
VisR Ultrasound for Noninvasively Interrogating Stromal Collagen Organization in Women as a Breast Cancer Biomarker: Evaluation of Anisotropy in Cancer Patients
Purpose: This study will evaluate how measurements of tissue stiffness, viscosity, and anisotropy using non-invasive ultrasound imaging correlate with breast tumor malignancy and response to chemotherapy.
- Trial name
- NCT06878547
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Cancer
E-MOSAIC Electronic Tool to Monitor Symptoms
RATIONALE: A hand held electronic tool used to monitor symptoms and assess quality of life may improve communication between patients and their doctors and improve the ability to plan treatment for patients with advanced cancer…
- Trial name
- NCT00477919
- Where
- 7 sites in Switzerland
- Volunteers
- 264 people
- Sponsor
- Swiss Cancer Institute
Cancer
Caspofungin Acetate in Treating Aspergillosis in Patients With Hematologic Cancer or in Patients Who Have Undergone a Stem Cell Transplant
RATIONALE: Antifungals, such as caspofungin acetate, may be effective in treating fungal infections caused by chemotherapy or stem cell transplant.
- Trial name
- NCT00110045
- Testing
- caspofungin acetate
- Where
- 13 sites in Belgium, France and 5 more
- Volunteers
- 171 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Breast Cancer, Breast Cancer Female
Resistance and Aerobic Exercise for Prevention in Women With Dense Breasts (REP-D)
The goal of this study is to learn more about how exercise might lower the risk of developing breast cancer in women with dense breast tissue by studying changes that occur in breast tissue and blood as a result of participating…
- Trial name
- NCT06322888
- Testing
- Exercise Training Program
- Where
- 2 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Fatigue, Breast Cancer Female
Exercise Therapy and Cognitive Behavioural Therapy for Fatigue in Female Cancer Patients in Singapore
The purpose of this research study is to investigate the acceptability, feasibility, and effectiveness of exercise therapy and cognitive behavioral therapy (CBT) in improving fatigue levels and breast cancer treatment adherence…
- Trial name
- NCT07116161
- Testing
- Graded Exercise Therapy Arm (GET), Experimental: Exercise Therapy (GET) plus Cognitive Behavioural Therapy (CBT)
- Where
- 4 sites in Singapore
- Volunteers
- 100 people
- Sponsor
- National Cancer Centre, Singapore
Breast Cancer Stage I, Breast Cancer Stage II
Effect of Physical Training Program on the Exercise Adherence for Breast Cancer Survivor
Breast cancer (BC) is one of the most common cancers among women worldwide, with survival rates steadily improving due to advances in early detection and treatment.
- Conditions
- Breast Cancer Stage I, Breast Cancer Stage II, Breast Cancer Stage III, Breast Cancer Stage IIIA
- Trial name
- NCT06771635
- Testing
- concurrent, Health Education Session
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- Universidad de Burgos
Primary Invasive Malignant Neoplasm of Female Breast, Carcinoma Breast
Study of AVB-620 in Women With Primary, Nonrecurrent Breast Cancer Undergoing Surgery
Phase 2, open-label study of AVB-620 in women with primary, nonrecurrent and nonmetastatic breast cancer undergoing surgery.
- Conditions
- Primary Invasive Malignant Neoplasm of Female Breast, Carcinoma Breast, Breast Cancer Female, Carcinoma, Ductal, Breast
- Trial name
- NCT03113825
- Testing
- Investigational Imaging device, AVB-620
- Where
- 13 sites in United States
- Volunteers
- 92 people
- Sponsor
- Avelas Biosciences, Inc.
Metastatic Cancer, Cancer
A Study of BIND-014 Given to Patients With Advanced or Metastatic Cancer
The goal of this Phase 1 clinical research study is to find the highest safe dose of BIND-014 that can be given in the treatment of patients with advanced or metastatic cancer.
- Conditions
- Metastatic Cancer, Cancer, Solid Tumors
- Trial name
- NCT01300533
- Testing
- BIND-014
- Where
- 6 sites in United States
- Volunteers
- 58 people
- Sponsor
- BIND Therapeutics
Breast Neoplasm Malignant Female
Expanded Access Protocol for Subjects Previously Treated With Gedatolisib in B2151009
Continued access to treatment for subjects who continue benefit from therapy with gedatolisib in combination with palbociclib, and fulvestrant or letrozole.
- Trial name
- NCT05134922
- Testing
- Gedatolisib
- Where
- 5 sites in United States
- Sponsor
- Celcuity Inc
Breast Cancer Female
Feasibility of High Levels of Energy Expenditure From Physical Activity for Breast Cancer Survivors
The purpose of the study is to demonstrate that breast cancer survivors who need to lose weight are able to follow a weight loss program which combines modest calorie restriction with a graduated activity program..
- Trial name
- NCT02963740
- Testing
- Supervised Exercise, Home-based Exercise, Group Phone Calls
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Kansas Medical Center
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
A Blended e-Health Intervention to Improve Fear of Progression in Women With Gynecologic or Breast Cancer
This clinical trial studies whether an intervention supported by technology (blended e-health intervention) works to improve fear of progression (FOP) in women with gynecologic or breast cancer.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8
- Trial name
- NCT07741968
- Testing
- Best Practice, Interview, Supportive Care
- Where
- 11 sites in United States
- Volunteers
- 126 people
- Sponsor
- City of Hope Medical Center
Breast Cancer Female
Radioguided Occult Lesion Localisation by Indocyanine Green
Breast cancer is the most common cancer in women. It is the main cause of cancer deaths among women. The incidence of non-palpable tumors is estimated at 60%.
- Trial name
- ROLL-1 (NCT03313908)
- Testing
- detection of the tumor lesion
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Montpellier
Breast Cancer Female NOS
Effect of an Educational Intervention in Women With Breast Cancer (EDU-INT-BC)
This study aims to evaluate the effect of an educational intervention on sexual function and therapeutic adherence among women with breast cancer followed in the medical oncology department of Ibn Tofail Hospital, affiliated with…
- Trial name
- EDU-INT-BC (NCT07367074)
- Testing
- Therapeutic Education Program for Women With Breast Cancer
- Where
- Morocco
- Volunteers
- 62 people
- Sponsor
- Instituts Supérieurs des Professions Infirmières et Techniques de Santé, Morocco
Hormone Dependent Neoplasms, Breast Cancer Female
HOrmone Therapy Immediately After Histological Diagnosis of Breast Cancer
Breast Cancer is a public health issue worldwide. The time from diagnosis to treatment initiation varies from country to country and regionally within a country.
- Trial name
- HOTBreast (NCT03111615)
- Testing
- Aromatase Inhibitors
- Where
- Portugal
- Volunteers
- 90 people
- Sponsor
- Centro Hospitalar Lisboa Ocidental
Cancer
Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced or Refractory Solid Tumors
RATIONALE: Drugs used in chemotherapy, such as paclitaxel albumin-stabilized nanoparticle formulation, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00499291
- Testing
- paclitaxel albumin-stabilized nanoparticle formulation, gene expression analysis, laboratory biomarker analysis
- Sponsor
- Eastern Cooperative Oncology Group
Early-stage Breast Cancer, Breast Cancer Female
The ConnectedCancerCare Pilot Study (CCC)
This study is an NCI-funded, randomized control pilot trial to evaluate: (1) the feasibility and acceptability of a web-based, personalized navigation tool (ConnectedCancerCare) and (2) explore whether the tool improves delivery…
- Conditions
- Early-stage Breast Cancer, Breast Cancer Female, Survivorship, Cancer Survivors
- Trial name
- CCC (NCT03618017)
- Testing
- CCC website, Static care plan
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Michigan Rogel Cancer Center
Adrenocortical Carcinoma, Breast Cancer
Tumor Necrosis Factor in Patients Undergoing Surgery for Primary Cancer or Metastatic Cancer
RATIONALE: Biological therapies, such as tumor necrosis factor, may stimulate the immune system in different ways and stop tumor cells from growing.
- Conditions
- Adrenocortical Carcinoma, Breast Cancer, Colorectal Cancer, Gastrointestinal Cancer
- Trial name
- NCT00436410
- Testing
- colloidal gold-bound tumor necrosis factor, electron microscopy, pharmacological study
- Where
- 2 sites in United States
- Volunteers
- 108 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Breast Neoplasm Female
Neoadjuvant Weekly Paclitaxel and Biomarkers of Therapy Response
The hypothesis of this study is that paclitaxel levels increase chromosomal instability (CIN) in tumors and this is lethal to tumors that have pre-existing CIN. Treatment will be administered on an outpatient basis.
- Trial name
- NCT03096418
- Testing
- Paclitaxel
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Wisconsin, Madison
Breast Cancer Female, Mastectomy
Opting for Breast Reconstruction After Mastectomy or Not: Search for Influencing Factors
The purpose of this study is to investigate the factors influencing the decision about breast reconstruction after breast amputation for breast cancer.
- Conditions
- Breast Cancer Female, Mastectomy, Breast Reconstruction
- Trial name
- NCT03039348
- Testing
- semi-structured interview using a questionnaire
- Volunteers
- 100 people
- Sponsor
- Universitair Ziekenhuis Brussel
Breast Cancer Female
Neoadjuvant Biomarker ResearcH Study of Palbociclib Combined With Endocrine Therapy in Estrogen Receptor Positive/HER2 Negative Breast CAncer (NeoRHEA)
This is an open-label, single arm, phase 2 trial that will include pre or post-menopausal female subjects, that have ER-positive, HER2-negative early breast cancer.
- Trial name
- NeoRHEA (NCT03065621)
- Testing
- Palbociclib
- Where
- 5 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Jules Bordet Institute