Clinical trials: Malnutrition, Child
Child Malnutrition
7-Day vs 1-Day Packaging for Small Quantity Lipid-Based Nutrient Supplements in Ghana (SQLNS:7D-1D Comparison)
This cluster-randomized crossover trial evaluates whether the packaging format of small-quantity lipid-based nutrient supplements (SQ-LNS) affects caregiver adherence and acceptability when SQ-LNS are delivered through routine…
- Trial name
- SQLNS:7Dv1D (NCT07129109)
- Testing
- small-quantity lipid-based nutrient supplements (SQ-LNS)
- Where
- Ghana
- Volunteers
- 505 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Acute Malnutrition, Severe, Malnutrition, Child
Increasing the Coverage of Severe Acute Malnutrition (SAM) Treatment in Ethiopia
The R-SWITCH intervention aims to address the low coverage of treatment for severe wasting (SAM) by leveraging existing community groups to deliver an integrated package focused on prevention, screening, referral, and treatment…
- Conditions
- Acute Malnutrition, Severe, Malnutrition, Child, Wasting
- Trial name
- R-SWITCH (NCT06380504)
- Testing
- R-SWITCH integrated intervention package
- Where
- Ethiopia
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Malnutrition
Comparison of an Alternative Therapeutic Food for the International Food Aid Market to a Standard Ready-to-use Therapeutic Food (RUTF) for the Treatment of Severe Acute Malnutrition in Children
In this clinical non-inferiority trial, two foods will be compared for the treatment of SAM, testing the hypothesis that the difference in recovery rates and growth between the two test groups will be no greater than 5 percent.
- Trial name
- NCT03407326
- Testing
- Alternative RUTF, Standard RUTF
- Where
- Sierra Leone
- Volunteers
- 1,568 people
- Sponsor
- Washington University School of Medicine
Child Malnutrition, Wasting Syndrome
Laser Height Measuring Device Study in Vietnam
This study will evaluate whether a portable laser device can accurately measure the height and length of children younger than 5 years in Quang Nam, Vietnam.
- Conditions
- Child Malnutrition, Wasting Syndrome, Stunting
- Trial name
- NCT07906067
- Testing
- Laser Height/Length Measuring Device, ShorrBoard
- Where
- Vietnam
- Volunteers
- 571 people, healthy volunteers welcome
- Sponsor
- World Vision US
Severe Acute Malnutrition
Ready to Use Therapeutic Food (RUTF) in Severe Malnourished Children
1. RUTF would be more effective (quicker catch-up growth by promoting more tissue accrue resulting decrease stay in rehabilitation ward) in treating children with SAM during the rehabilitation phase than khichuri /halwa; 2.
- Trial name
- RUTF (NCT01331044)
- Testing
- Plumpy Nut, Khichuri and Halwa
- Where
- Bangladesh
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Celiac Disease in Children, Gluten Enteropathy
Influence of a Gluten Free Food Guide on Diet Quality and Adherence to the GFD in Youth With Celiac Disease
Celiac disease (CD) is an autoimmune gastrointestinal disease that is caused by intolerance to gluten in the diet. The mainstay of treatment is a gluten-free diet (GFD).
- Conditions
- Celiac Disease in Children, Gluten Enteropathy, Diet; Deficiency, Adherence, Treatment
- Trial name
- NCT06038344
- Testing
- Gluten-free food guide teaching
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Stunting of Growth, Chronic Malnutrition
Pilot Study of a Modified Therapeutic Food Compared With a Standard Nutrient Supplement in Young Children in Rural Guatemala
The goal of this clinical trial is to learn whether a modified food supplement is acceptable and well tolerated by children aged 12 to 24 months with mild-to-moderate stunting in rural Guatemala.
- Trial name
- NCT07804667
- Testing
- Modified Therapeutic Food Formulation, Nutri Listo SQ-LNS
- Where
- Guatemala
- Volunteers
- 36 people
- Sponsor
- Wuqu' Kawoq, Maya Health Alliance
Helicobacter Pylori Infection, Iron Deficiency Anemia
Is Helicobacter Pylori Infection a Cause or Treatment Failure of Iron Deficiency Anemia in Children in Bangladesh?
Helicobacter pylori is recognized as a major gastrointestinal pathogen in developing countries. This microorganism infects up to 60% of children less than five years in those countries and is strongly associated with chronic…
- Conditions
- Helicobacter Pylori Infection, Iron Deficiency Anemia, Not Severely Malnourished, No Systemic Infection
- Trial name
- NCT00284700
- Testing
- Iron
- Where
- Bangladesh
- Volunteers
- 260 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Child Developmental Delay, Child Malnutrition
Maternal B12 Supplementation to Improve Infant B12 Deficiency and Neurodevelopment
Vitamin B12 plays a key role in the development and normal functioning of the brain and nervous system. Unborn and new-born infants derive their vitamin B12 stores almost entirely from maternal B12 stores.
- Conditions
- Child Developmental Delay, Child Malnutrition, Maternal Exposure, Vitamin B 12 Deficiency
- Trial name
- MATCOBIND (NCT03783104)
- Testing
- B12 Supplement
- Where
- 2 sites in India, Nepal
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University College, London
Protein Malnutrition
Formative Research Study to Address Protein Intake in Children and Analysis of Breast Milk Nutrient Content in Mothers
This formative research seeks to explore the use of egg (as a potential source of protein) as nutritional supplement for young children aged 6-8 months of either sex and breast milk composition of mothers of infants under 6…
- Trial name
- NCT03140696
- Testing
- Egg Alone, Egg and ready to use supplementary food (RUSF), Egg and breast milk
- Where
- Bangladesh
- Volunteers
- 30 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Severe Acute Malnutrition
Comparison of Treatment of SAM in Children 6-59 Months With RUTF and RUSF in Umerkot, Sindh, Pakistan
In Pakistan, around 15% of children under five are wasted, which is almost twice that of the global prevalence 7.5%. There is a demand for a reliable and consistent locally available severe acute malnutrition (SAM) treatment…
- Trial name
- NCT04174846
- Testing
- Ready-to-use therapeutic food (RUTF), Ready-to-use-supplementary food (RUSF)
- Where
- Pakistan
- Sponsor
- Aga Khan University
Growth Retardation, Malnutrition
Nutrition Education Package for Infants and Young Child Feeding and Health in Rural Tanzania
Building on the success of community-based peer education and counselling in breastfeeding, it is possible to address young child feeding and health practices in the surveyed district.
- Trial name
- NECTAc (NCT02249754)
- Testing
- Nutrition education, Routine health education
- Where
- Tanzania
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sokoine University of Agriculture
Epilepsy, Vitamin D Deficiency
Vitamin D Supplementation to Prevent Vitamin D Deficiency for Children With Epilepsy
To determine the maintenance dose of vitamin D supplementation required for children with epilepsy to maintain normal vitamin D level.
- Trial name
- NCT03536845
- Testing
- Vitamin D 3
- Where
- Saudi Arabia
- Volunteers
- 116 people
- Sponsor
- King Saud University
Malnutrition, Wasting
Nutritional Impact of Moringa Oleifera Leaf Supplementation in Mothers and Children
Studies to date on the effects of Moringa oleifera in diabetes and anemia and animal studies that examine the utility of moringa for increased milk and litter yield are of small scale, however high-quality large-scale placebo or…
- Conditions
- Malnutrition, Wasting, Growth Failure
- Trial name
- NCT04587271
- Testing
- Moringa oleifera (high dose), Moringa oleifera (low dose)
- Where
- 2 sites in Kenya
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Suzanna L Attia
Malnutrition
Malnutrition and Outcome in Hospitalized Children in Europe
Malnutrition in children has even more severe consequences on disease course and long-term health than malnutrition in adults. According to prior studies, malnutrition affects about 15-30 % of hospitalized children in Europe…
- Trial name
- NCT01132742
- Where
- 14 sites in Croatia, Denmark and 9 more
- Volunteers
- 2,567 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Malnutrition, Worm Infestation
Deworming and Vitamin A (DEVTA) Prepilot Study
Background. More than a third of the world's population is infected with intestinal nematodes. A majority of these infections occur in children.
- Conditions
- Malnutrition, Worm Infestation, Under-Fives
- Trial name
- NCT00396500
- Testing
- Albendazole (400 mg) and/or Vitamin a
- Where
- India
- Volunteers
- 4,000 people
- Sponsor
- King George's Medical University
Obesity, Vitamin D Deficiency
Vitamin D Supplementation in Psychiatric Illnesses
Children and adolescents with psychiatric illnesses who are treated with medications called second generation antipsychotic agents (SGA) often gain excessive weight during their treatment with these medications.
- Conditions
- Obesity, Vitamin D Deficiency, Psychosis, Schizophrenia
- Trial name
- VDSS (NCT01004354)
- Testing
- Ergocalciferols
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Massachusetts, Worcester
Malnutrition, Stunting of Growth
Acceptability of a Cereal for Complementary Feeding of Infants and Young Children Made From Caterpillars
Two in every three infants in rural areas of the Democratic Republic of Congo (DRC) suffer from stunting of linear growth by 12 months of age.
- Trial name
- CAT01 (NCT01258647)
- Testing
- caterpillar cereal
- Where
- Republic of the Congo
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Malnutrition in Children, Children Exposed to HIV
A Trial Testing a Two-way SMS Platform to Recognize and Prevent Wasting Among HIV-infected and HIV-exposed Uninfected Children in Kenya
The goal of this study is to test if a two-way text-message (SMS) maternally administered malnutrition monitoring system (MAMMS) that delivers infant and young child feeding (IYCF) education and supports caregivers in monitoring…
- Trial name
- MAMMS IYCF R33 (NCT06842732)
- Testing
- Maternal Administered Malnutrition Monitoring System - Infant and Young Child Feeding (MAMMS IYCF) intervention, Standard of Care (SOC)
- Where
- 2 sites in Kenya
- Volunteers
- 776 people, healthy volunteers welcome
- Sponsor
- University of Washington
Acute Respiratory Infections, Critical Illness in Children
Serum Vitamin D Status in Critically Ill Children With Acute Respiratory Infections
Acute respiratory infections (ARIs) are among the leading causes of hospitalization, morbidity, and mortality in children worldwide, particularly among critically ill patients admitted to pediatric intensive care units (PICUs).
- Conditions
- Acute Respiratory Infections, Critical Illness in Children, Vitamin D Deficiency, Pediatric Respiratory Infections
- Trial name
- VITD-ARI (NCT06547749)
- Testing
- Serum 25-Hydroxyvitamin D Assessment
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Assiut University