Clinical trials: Malnutrition, Child
Congenital Heart Disease in Children, Post-cardiac Surgery
To Assess the Efficacy of Early Administration of Energy Enriched and Protein Enriched Formula in Post Cardiac Repair Infants: a Randomized Controlled Trial, Comparative Study
Congenital heart disease (CHD) is a public health problem, A substantial percentage of infants and toddlers with CHD undergo cardiopulmonary bypass surgery.
- Conditions
- Congenital Heart Disease in Children, Post-cardiac Surgery, Malnutrition, Infant
- Trial name
- NCT05826769
- Testing
- Energy- Protein Enriched Nutritional Formula
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Global Acute Malnutrition (GAM)
Integrated Treatment Protocol for Acute Malnutrition: A Non Inferiority Trial in Burkina Faso
MUAC only is a pilot trial external control carried out between January 2017 and December 2017 in the Yako district (northern region), Burkina Faso.
- Trial name
- MUAC-Only (NCT03027505)
- Testing
- Ready to Use Therapeutic Food (RUTF)
- Where
- Burkina Faso
- Volunteers
- 4,958 people
- Sponsor
- Alliance for International Medical Action
Malnutrition, Stunting
Child Health, Nutrition and Microbiome Development
Childhood malnutrition is a global public health issue with devastating consequences on the health, well-being, and psychosocial development of children.
- Conditions
- Malnutrition, Stunting, Wasting, Underweight
- Trial name
- CHAMP (NCT05793294)
- Where
- 2 sites in Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Child, Malnutrition
Effectiveness of a Ready-to-Use-Food (RUF) Supplement to Prevent Acute Child Malnutrition
The overall objective of this project is to assess the effectiveness and cost-effectiveness of RUF (ready-to-Use Food, Plumpy Doz(r)) to prevent moderate acute malnutrition in children aged 6-36 months if embedded in a program of…
- Trial name
- PREAMA (NCT01154595)
- Testing
- Plumpy Doz(r) - Ready-to-Use Food, Food-for-Training
- Where
- Chad
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Action Contre la Faim
Health Literacy, Nutrition, Healthy
Addressing Food Insecurity: Plant-Based Food Prescription Program
Reduce food insecurity by improving plant-based health food consumption, access, health and nutrition literacy and the health of the food-insecure families we serve.
- Conditions
- Health Literacy, Nutrition, Healthy, Nutrition Poor, Food Insecurity
- Trial name
- NCT06614920
- Testing
- Plant-Based Food Provision (with or without food prescription), Plant-Based Nutrition Education
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Miami
Congenital Heart Disease, Dysbiosis
The Influence of Probiotics on Metabolome and Heart Rate Variability in Heart Failure of Structure Heart Disease
Poor body weight gain and failure to thrive is a very common condition in patients with congenital heart disease (CHD) with advanced HF and/or cyanosis, which are considered a predictor of morbidity and complicate the prognosis…
- Conditions
- Congenital Heart Disease, Dysbiosis, Malnutrition, Child, Probiotics
- Trial name
- NCT06872320
- Testing
- Lactobacillus Rhamnosus
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Chang Gung Memorial Hospital
X-linked Hypophosphatemia (XLH)
Effective Dosing of Burosumab in XLH
X-linked hypophosphataemia (XLH) is a rare, hereditary condition. The genetic defect leads to low blood phosphate levels and vitamin D suppression. Phosphate is required for strong bones and teeth and to store energy in cells.
- Trial name
- NCT07183579
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Nottingham
Micronutrient Deficiencies, Anemia
Effectiveness of Multiple Micro-nutrient Fortified Fudge on Nutritional Status of 3-5 Years of Age Children
Multiple micro-nutrient deficiencies in Pakistan is wide spread, there is dire need to address these by using smart solutions, among them multiple fortified product (fudge) is an alternate possible way to address this issue.
- Conditions
- Micronutrient Deficiencies, Anemia, Fortification, Undernutrition
- Trial name
- NCT03450174
- Testing
- Formative messgaes, Fortified product, Fortified product plus
- Where
- Pakistan
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Vitamin A Deficiency
Retinol Equivalence of Plant Carotenoids in Children
To determine vitamin A value of beta-carotene in oil capsule, spinach, and golden rice. The experiments will be conducted in children (ages 7-9) with/without adequate vitamin A nutrition.
- Trial name
- NCT00082420
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Growth Retardation, Malnutrition
Nutrition Education Package for Infants and Young Child Feeding and Health in Rural Tanzania
Building on the success of community-based peer education and counselling in breastfeeding, it is possible to address young child feeding and health practices in the surveyed district.
- Trial name
- NECTAc (NCT02249754)
- Testing
- Nutrition education, Routine health education
- Where
- Tanzania
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sokoine University of Agriculture
Childhood Cancer, Child Malnutrition
Body Composition and Nutritional Status in Pediatric Patients With Hematological Malignancies
Introduction: Annually 400,000 children are diagnosed with cancer in the world. Approximately 90% live in low/middle-income countries, with survival rates of 10-30%.
- Conditions
- Childhood Cancer, Child Malnutrition, Childhood Obesity
- Trial name
- HM (NCT04764695)
- Testing
- D2O dilution technique
- Where
- Mexico
- Volunteers
- 38 people
- Sponsor
- Universidad de Sonora
Vitamin D 25-Hydroxylase Deficiency, Undernutrition
Impact of Trout Fish, Cow Milk With Egg, Vitamin D Supplementation, and Dietary Education on Vitamin D Status, Undernutrition, and Neurocognitive Outcomes Among School Children in Pakistan: An Open-label Individually Randomized Controlled Trial
Vitamin D deficiency and undernutrition are major public health concerns globally, particularly among children in low-resource and high-altitude settings.
- Conditions
- Vitamin D 25-Hydroxylase Deficiency, Undernutrition, Neurocognitive Development
- Trial name
- NCT07864662
- Testing
- Vitamin D supplement 4000 IU weekly, 200 grams of cooked trout fish, 250 milliliters of whole cow milk + whole egg
- Where
- Pakistan
- Volunteers
- 304 people
- Sponsor
- Aga Khan University
Helicobacter Pylori Infection, Iron Deficiency Anemia
Is Helicobacter Pylori Infection a Cause or Treatment Failure of Iron Deficiency Anemia in Children in Bangladesh?
Helicobacter pylori is recognized as a major gastrointestinal pathogen in developing countries. This microorganism infects up to 60% of children less than five years in those countries and is strongly associated with chronic…
- Conditions
- Helicobacter Pylori Infection, Iron Deficiency Anemia, Not Severely Malnourished, No Systemic Infection
- Trial name
- NCT00284700
- Testing
- Iron
- Where
- Bangladesh
- Volunteers
- 260 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Dietary Supplementation, Severe Acute Malnutrition
Safety Trial of F-60 Among Children Hospitalized With SAM
The current WHO-recommended F-75 diet for stabilization of SAM has remained largely unchanged since its development in the 1990s.
- Conditions
- Dietary Supplementation, Severe Acute Malnutrition, Children
- Trial name
- NCT07752628
- Testing
- F75 milk feeds, F60 milk feeds
- Where
- Bangladesh
- Volunteers
- 320 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Celiac Disease in Children, Gluten Enteropathy
Influence of a Gluten Free Food Guide on Diet Quality and Adherence to the GFD in Youth With Celiac Disease
Celiac disease (CD) is an autoimmune gastrointestinal disease that is caused by intolerance to gluten in the diet. The mainstay of treatment is a gluten-free diet (GFD).
- Conditions
- Celiac Disease in Children, Gluten Enteropathy, Diet; Deficiency, Adherence, Treatment
- Trial name
- NCT06038344
- Testing
- Gluten-free food guide teaching
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Malnutrition (Calorie), Protein-energy Malnutrition
Composite Flour Cookies for Improving Nutrition in Malnourished Children
Malnutrition is a major public health concern among children in developing countries, leading to impaired growth and increased risk of morbidity.
- Trial name
- CFC-MAL (NCT07504133)
- Testing
- Composite Flour Cookies
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Mairaj Noor
Child Malnutrition, Behavior, Maternal
Mobile Gaming App to Improve Child Nutrition in Nigeria
Undernutrition among children born to teenage mothers deserves urgent attention in Nigeria, where 27.2% of girls (15-19 years) living in rural areas have begun childbearing.
- Trial name
- NCT05181293
- Testing
- Mobile Gaming App for Nutrition Intervention
- Where
- Nigeria
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Immunity to Polio Vaccines in Malnourished Infants, Immunity to Polio Vaccines in Non-malnourished Infants
IPV in Moderate to Severe Chronic Malnourished 9-12 Month Old Children in Karachi.
Chronic malnutrition is associated with lack of effective gut immunity which is a possible explanation for why we see polio cases among a proportion of children who have received 7 or more doses of OPV.Our proposed idea is to…
- Trial name
- MIPV (NCT01695798)
- Testing
- Injectable polio vaccine and Bivalent oral polio vaccine
- Where
- Pakistan
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Complementary Feeding
Improving Growth and Cognitive Development of the Disadvantaged Young Children in Resource Poor Setting
1. Burden: The period from birth to two years of age is the "critical window" for the promotion of optimal growth, health, and development.
- Trial name
- NCT05805514
- Testing
- Animal source of food and psychosocial stimulation, Animal source of food, Control
- Where
- Bangladesh
- Volunteers
- 627 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Obesity, Childhood
Monthly Boluses Versus Daily Doses for Correcting Blood Vitamin D Deficit in Obese Children and Adolescents
Childhood obesity is one of the most serious public health challenges of the 21st century, with an increasing prevalence over time in developed countries.
- Trial name
- OBEVIDOS (NCT03516968)
- Testing
- Monthly bolus of cholecalciferol per os, Daily dose of cholecalciferol per os
- Where
- 4 sites in France
- Volunteers
- 68 people
- Sponsor
- Hospices Civils de Lyon