Clinical trials: Mammaplasty
Breast Hypertrophy
Vertical Scar Versus Inferior Pedicle Reduction Mammoplasty
Main research question: Is vertical scar reduction mammoplasty superior when compared to inferior pedicle reduction mammoplasty in terms of patient quality of life and cost-effectiveness? Why is this research important?: There is…
- Trial name
- NCT00149344
- Testing
- Vertical scar versus inferior pedicle reduction mammoplasty
- Where
- Canada
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- McMaster University
Micromastia, Breast Ptosis
Autologous Fat Grafting to the Breast
Structural fat grafting is a form of tissue transfer where the autologous fat is harvested and subsequently transferred to a different region of the body at the same setting.
- Conditions
- Micromastia, Breast Ptosis, Implant Failure, Breast Reconstruction
- Trial name
- NCT00775788
- Testing
- Autologous Fat Grafting to Breasts
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Breast Cancer
TIVA Admnistration and Autologous Fat Transfer in Breast Reconstruction
The aim of the present study is to investigate the effect of intravenous anesthetics versus the administration of volatile anesthetics on stress and pain levels during autologous fat transfer for breast reconstruction in a Day…
- Trial name
- TIVA (NCT04077827)
- Testing
- Propofol
- Where
- Greece
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Safety and Performance, Breast Tissue Expander
Post-marketing Clinical Monitoring of Safety and Performance of Breast Tissue Expander for Breast Reconstruction
The study investigates the safety and performance of Silimed® brand breast tissue expander in women born with indication for breast reconstruction.
- Trial name
- STEPS-R (NCT06981481)
- Testing
- Breast tissue expander
- Where
- 3 sites in Brazil
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Silimed Industria de Implantes Ltda
Breast Implant; Complications, Breast Implantation; Methods, Safety and Performance
Safety and Performance of Motiva® Sizers
The Motiva® Sizer clinical study is a four-year, multicenter, post-marketing, and cohort study, designed to confirm the safety and performance of Motiva® Sizer in breast augmentation or reconstruction procedures.
- Conditions
- Breast Implant; Complications, Breast Implantation; Methods, Safety and Performance, Mammaplasty, Breast Reconstruction
- Trial name
- NCT06274736
- Testing
- Motiva Sizer
- Where
- Costa Rica
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Establishment Labs
Breast Cancer
Laser Speckle Imaging During Breast Reconstruction
Around 3500 women a year have surgery to reconstruct a breast/s after cancer. Breast reconstruction can have a positive impact on their lives, but unfortunately 3 or 4 in 10 women have problems with healing after their operation.
- Trial name
- SIMBAR (NCT06523452)
- Testing
- Laser Speckle Imaging
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Pain, Postoperative
Multicentric Risk Evaluation of Autologous Fat Grafting Procedure
Autologous fat grafting, also known as lipofilling, is a surgical technique consisting in the processing and transfer of adipose tissue from one area in our organism (hips, thighs) to region which in need of reconstructive and…
- Trial name
- NCT04130373
- Testing
- Autologous fat grafting procedure, Breast reconstruction
- Where
- Italy
- Volunteers
- 6,510 people, healthy volunteers welcome
- Sponsor
- Humanitas Clinical and Research Center
Pain, Postoperative
Single and Double Injection Bilateral Thoracic Paravertebral Blocks in Reduction Mammaplasty
This study compares the analgesic effects and dermatomal blockade distributions of single and double injection bilateral thoracic paravertebral block (TPVB) techniques in patients undergoing reduction mammaplasty.
- Trial name
- NCT04517331
- Testing
- Thoracic paravertebral block-single injection, Thoracic paravertebral block-double injection
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Pain
Enhanced Recovery After Bilateral Reduction Mammaplasty
This single-center, clinical trial is being conducted to determine whether non-narcotic pain regiments are as effective as narcotic-based regiments in reducing post-operative pain in patients undergoing breast reduction in the…
- Trial name
- NCT04558840
- Testing
- Macromastia
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Mastectomy, Mastectomy Patient
A Study on Pain After Breast Reconstruction
The purpose of this study is to find out how common persistent postmastectomy pain (PPMP) is among people who have had a mastectomy and breast reconstruction surgery for their breast cancer.
- Conditions
- Mastectomy, Mastectomy Patient, Mastectomy and Breast Reconstruction, Breast Reconstruction
- Trial name
- NCT06627582
- Testing
- PROMIS Scale v2.0 - Pain Intensity 3a, PROMIS 29+2, PROMIS Scale v2.0 - Nociceptive Pain Quality 5a
- Where
- 7 sites in United States
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer
Optical Spectroscopy During Breast Cancer Surgery and Core Needle Biopsy
The objective of the proposed research is to develop new diagnostic modalities based on optical spectroscopy (auto fluorescence, absorption, and scattering) for the diagnosis of breast cancer and test its performance as an…
- Trial name
- NCT00734838
- Testing
- High Resolution Microendoscope
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Duke University
Pain, Postoperative, Non-Opioid Pain Management
Virtual Reality After Breast Reconstruction Surgery
This is a pilot study of virtual reality (VR) non-opioid management for women undergoing mastectomy and implant-based reconstruction.
- Conditions
- Pain, Postoperative, Non-Opioid Pain Management, Virtual Reality
- Trial name
- VR4BR (NCT03801616)
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Breast Cancer
ciNPT in Autologous Abdominal Tissue Breast Reconstruction
In women who undergo mastectomy for the treatment of breast cancer, autologous reconstruction using the deep inferior epigastric perforator (DIEP) flap is a common surgical procedure that aims to restore both the appearance and…
- Trial name
- NCT04985552
- Testing
- DIEP Breast Reconstruction, ciNPT, Conventional Tape Dressings
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- McMaster University
Breast Cancer
Intraoperative Pathway in DIEP Flap Breast Reconstruction
Efficiency in the operating room can be difficult in long cases with multiple surgeons. We used a team based approach to develop an intraoperative pathway for microsurgical breast reconstruction with a deep inferior epigastric…
- Trial name
- NCT00543764
- Testing
- pathway
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Respiratory Function, Breast Reconstruction
The Effect of Breast Reconstruction Surgery Using Tissue Expanders on Respiratory Functions
This study evaluates the effect of breast reconstruction surgery on respiratory functions. 45 patients elected for unilateral or bilateral breast reconstruction surgery will go through respiratory function examinations a month…
- Trial name
- NCT02491762
- Testing
- respiratory function tests
- Where
- Israel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Yaron Har-Shai
Recurrent Ptosis of the Breast
Seri Surgical Scaffold Support of the Lower Pole of the Breast
Will the use of an FDA approved highly purified silk scaffold; Seri Surgical Scaffold help shape and hold the breast up on the chest preventing re-stretching and bottoming out of the breast in breast reduction or…
- Trial name
- SeriSupport (NCT02016612)
- Testing
- Seri Surgical Scaffold
- Where
- 2 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Bengtson Center
Cicatrix
Intraoperative Hyaluronic Acid Gel Injection for Improvement of Scar Quality Following Reduction Mammaplasty
The purpose of this study is to determine the efficacy of hyaluronic acid gel injections compared to saline injections in improving scar quality in patients undergoing breast reduction surgery.
- Trial name
- NCT00958425
- Testing
- Hyaluronic acid gel, Saline
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority