Clinical trials: Management, Risk
HIV, Cardiovascular Disease
HealthMap: an Interactive Health Plan Randomised Trial to Prevent Cardiovascular Disease in People With HIV
The purpose of this study is to improve the health status of people living with HIV in Australia. The overall goal is to rigorously evaluate the impact of interactive health plans and self-management support on chronic condition…
- Trial name
- NCT02178930
- Testing
- Integrated self management support
- Where
- 14 sites in Australia
- Volunteers
- 731 people
- Sponsor
- Karen Klassen
Breast Cancer Survivorship, Weight Management
Weight Management After Cancer for Survivors in Rural Communities
This study is testing a new program called WeCan-Rural, designed to help breast cancer survivors manage symptoms and build healthy habits like eating well, staying active, and managing their weight.
- Conditions
- Breast Cancer Survivorship, Weight Management, Cardiovascular (CV) Risk, Breast Cancer
- Trial name
- WeCan-Rural (NCT07426952)
- Testing
- WeCan-Rural Program
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Sarcoma
Chemotherapy Plus Radiation Therapy Followed by Surgery in Treating Patients With Soft Tissue Sarcoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells.
- Trial name
- NCT00002791
- Testing
- filgrastim, dacarbazine, doxorubicin hydrochloride
- Where
- 237 sites in United States, Canada and 1 more
- Sponsor
- Radiation Therapy Oncology Group
Diabetes
Diabetes Outcomes and Unmet Resources
This study will refine and test the effectiveness of CareAvenue, an automated e-health tool that informs and activates patients with uncontrolled diabetes to take steps in accessing resources and engaging in self-care.
- Trial name
- NCT03950973
- Testing
- CareAvenue, Guest Assistance Program
- Where
- United States
- Volunteers
- 667 people
- Sponsor
- University of Michigan
Gambling Disorder
Repetitive Transcranial Magnetic Stimulation (rTMS) and Cognitive Behavioral Therapy (CBT) for Gambling Disorder
Treatment options for gambling disorder (GD) remain limited, with no pharmacotherapy proven effective. As of date, cognitive behavioral therapy (CBT) is the preferred therapy for GD, but the improvements often require months to…
- Trial name
- NCT06598501
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Volunteers
- 10 people
- Sponsor
- Universitas Indonesia
Breast Cancer
Breast Cancer Prevention and Screening Membership
The AdDePi-KS project aims to contribute to the renovation of the breast cancer screening program. In order to improve information to women on breast cancer risk factors and their participation in organized screening, but also to…
- Trial name
- AdDePi_KS (NCT05258539)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 189 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypertension, Diabetes Mellitus, Type 2
Effectiveness of a Case Management Model for Patients With Hypertension and Type II Diabetes in Chile
The purpose of this study is to evaluate whether a new model of health care for chronic patients, based on Case Management and guided by a nurse which targets the patient´s risk, is more effective than usual care at Primary…
- Trial name
- NCT02762695
- Testing
- Case Management, Usual Care
- Where
- Chile
- Volunteers
- 616 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Megakaryoblastic Leukemia (M7)
Alvocidib, Cytarabine, and Mitoxantrone in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
This randomized phase II trial is studying two different schedules of alvocidib to compare how well they work when given together with cytarabine and mitoxantrone in treating patients with newly diagnosed acute myeloid leukemia.
- Conditions
- Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0), Adult Acute Monoblastic Leukemia (M5a)
- Trial name
- NCT00795002
- Testing
- alvocidib, mitoxantrone hydrochloride, cytarabine
- Where
- 2 sites in United States
- Volunteers
- 78 people
- Sponsor
- National Cancer Institute (NCI)
Coronary Artery Disease
Risk-guided Disease managEment Plan to prevEnt CAD in Patients Treated With Previous Cancer
REDEEM-CAD is a prospective multi-centre study of CAD risk evaluation and management in cancer survivors 40-70 years with chemotherapy or radiotherapy >5 years ago.
- Trial name
- REDEEM-CAD (NCT05366153)
- Testing
- Coronary CT
- Where
- 2 sites in Australia
- Volunteers
- 748 people, healthy volunteers welcome
- Sponsor
- Baker Heart and Diabetes Institute
Students, Earthquake
The Effect of a Mobile Earthquake Education Application
This research aims to experimentally explore the effect of the mobile earthquake education application developed for high school students on the earthquake knowledge level and earthquake risk perception of high school students.
- Conditions
- Students, Earthquake, Education
- Trial name
- NCT06165263
- Testing
- Mobile earthquake education
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
High Blood Pressure
IMPlementation of gUideLines for the Management of Arterial hypertenSION. The IMPULSION Study
The objective of this protocol is to improve awareness, treatment, and control of arterial hypertension, within primary prevention of target organ damage, by implementing guidelines, after training of the participating physicians.
- Trial name
- IMPULSION (NCT00416611)
- Testing
- Implementation of guidelines
- Where
- Greece
- Volunteers
- 1,000 people
- Sponsor
- Hellenic Atherosclerosis Society
Hemodynamic MAP Stability
Closed-loop Control of Vasopressor Administration in Cardiac Surgery
Intraoperative hypotension and blood pressure variability are associated with postoperative complications in surgical patients. The investigators have developed a closed-loop vasopressor (CLV) controller that titrates…
- Trial name
- NCT04232007
- Testing
- closed-loop system for vasopressor administration
- Where
- Belgium
- Volunteers
- 3 people
- Sponsor
- Erasme University Hospital
Lung Cancer, High-Risk Cancer
Taiwan Real-world LDCT Screening Behavior and Outcome Research for High Risk Subjects Based on Health Promotion Administration
Lung cancer is the leading cause of mortality in the world, and also in Taiwan.Despite the researches and availability in new therapies, it causes the highest mortality and is one of the most preventable cancers as well.
- Conditions
- Lung Cancer, High-Risk Cancer, Smoking, Pollution; Exposure
- Trial name
- TRIO (NCT05557487)
- Testing
- Low dose computed tomography
- Where
- 7 sites in Taiwan
- Volunteers
- 6,618 people, healthy volunteers welcome
- Sponsor
- Gee-Chen Chang
Diabetes Mellitus, Type 2, Dyslipidemias
Curcumin's Effect on Diabetic Patients With Atherosclerotic Cardiovascular Risk
The aim of the study is to assess the safety and efficacy of Curcumin supplementation in combination to the conventional therapy in improving the clinical outcomes, oxidative stress and inflammation in diabetic patients with risk…
- Conditions
- Diabetes Mellitus, Type 2, Dyslipidemias, Hypertension
- Trial name
- NCT05753436
- Testing
- Puritans Pride Turmeric curcumin® 500 mg
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Ain Shams University
Acute Myeloid Leukemia
Intermittent Liposomal Amphotericin B Primary Prophylaxis
The purpose of this trial is to see which dose of liposomal amphotericin B is the safest when used as a preventer against invasive fungal infection in patients with acute leukaemia who are undergoing chemotherapy.
- Trial name
- NCT00451711
- Testing
- Liposomal amphotericin B
- Where
- 2 sites in Australia
- Volunteers
- 60 people
- Sponsor
- Bayside Health
Atrial Fibrillation, Heart Failure
Diagnostic Device Risk Management of Atrial Fibrillation and Heart Failure
The purpose of this study is to characterize the feasibility and impact of a diagnostic tool that may help clinicians identify when patients are at higher risk of visiting the hospital for a heart failure event.
- Trial name
- IDENTIFY-HF (NCT01486316)
- Testing
- Reveal XT® Insertable Cardiac Monitor, Heart Failure Risk Status Diagnostic
- Where
- 11 sites in United States
- Volunteers
- 24 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Stress Urinary Incontinence (SUI)
Evaluating SUI-100™, A Non-Invasive Device for the Treatment of Stress Urinary Incontinence
The goal of this pivotal clinical trial is to evaluate the safety and effectiveness of the SUI-100 device for the treatment of mild-to-moderate stress urinary incontinence (SUI) in females aged 22-70 years.
- Trial name
- SaHARA (NCT06862648)
- Testing
- Acoustic Stimulation Therapy Device
- Where
- 9 sites in United States
- Volunteers
- 130 people
- Sponsor
- Acoustic Wave Cell Therapy, Inc.
Diabetes Mellitus, Foot Ulcer
Becaplermin Use and Cancer Risk in a Patient Population of U.S. Veterans With Diabetes
The purpose of this study is to evaluate risk of cancer incidence and mortality associated with the use of REGRANEX (becaplermin) in patients with diabetes who are members of a U.S. Veterans Health Administration.
- Conditions
- Diabetes Mellitus, Foot Ulcer, Diabetic Foot, Diabetic Neuropathies
- Trial name
- NCT01235260
- Testing
- Becaplermin nonusers, Becaplermin users
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Mortality in Intensive Care Units, Complications Infection
Intensive Care Unit Risk Score
Subject of the planned project is the retrospective analysis of routine data of digital patient files of the Department for Anaesthesiology and Surgical Intensive Care Medicine, to test whether the predictive values of intensive…
- Conditions
- Mortality in Intensive Care Units, Complications Infection, Alarm Fatigue
- Trial name
- ICURS (NCT04661735)
- Where
- Germany
- Volunteers
- 60,000 people
- Sponsor
- Charite University, Berlin, Germany
Patient-Centered Care, Competency-Based Education
Evaluating the Impact of Operating Room Simulations on Communication Skills and Patient Safety (EIORS-CPS)
Simulation-based training has emerged as a valuable tool for enhancing communication skills among healthcare professionals. This study aimed to evaluate the impact of operating room (OR) simulations on the development of…
- Trial name
- EIORS-CPS (NCT06755203)
- Testing
- Operating Room Simulation Training
- Where
- Saudi Arabia
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- King Saud Medical City