Clinical trials: Management
Chronic Obstructive Pulmonary Disease
GECo: Implementation and Effectiveness of COPD Self Management Action Plans in Low and Middle Income Countries
This study will randomise people with clinically significant COPD (GOLD Grade B-D) to usual care or provision of a self-management action plan supported by monthly follow-up visits from a community health worker trained in the…
- Trial name
- GECo2 (NCT03359915)
- Testing
- COPD Self-Management Plan
- Where
- 3 sites in Nepal, Peru and 1 more
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University College, London
Fever, Infection
Personalised Risk Assessment in Febrile Illness to Optimise Real-life Management Across the European Union (PERFORM)
Childhood fever is a prevalent problem. Most febrile children who visit hospital improve without treatment, but a minority require treatment, and a few will have severe disease.
- Conditions
- Fever, Infection, Inflammation
- Trial name
- PERFORM (NCT03502993)
- Testing
- Validation of biomarker
- Where
- United Kingdom
- Volunteers
- 7,247 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Pain
Vibration and Shotblocker Use in Pregnant Women While Giving Tetanus + Diphtheria Vaccine
Tetanus-diphtheria vaccine administered to pregnant women may cause pain during and after administration. Due to the pain that may occur, the compliance of pregnant women towards the vaccine may be impaired.
- Trial name
- NCT05701904
- Testing
- Local mechanical vibration, Shotblocker group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Chronic Stable Angina
A Randomized, Open-label, Single-dose, Crossover Clinical Trial to Evaluate the Food Effect on the Pharmacokinetics of Dilatrend SR 64mg Capsule After Oral Administration in Healthy Male Volunteers
A randomized, open-label, single-dose, crossover clinical trial to evaluate the food effect on the pharmacokinetics of Dilatrend SR 64mg capsule after oral administration in healthy male volunteers.
- Trial name
- NCT01340248
- Testing
- Dilatrend 64mg capsule
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Blood Loss
Effect of Perioperative Tranexamic Acid on Blood Loss During Management of Maxillofacial Trauma
This is a prospective, randomized, double-blind study investigating whether intravenous tranexamic acid has any effect on blood loss during maxillofacial trauma surgery, or the subsequent postoperative sequelae.
- Trial name
- NCT04494126
- Testing
- Tranexamic acid
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- College of Medical Sciences Teaching Hospital. Nepal
Asthma
Online Asthma Self-Management for Children Aged 5-10 and Their Parents
The potential benefits of this research to public health include improved understanding of cultural factors in pediatric asthma self-management, improved self-management skills for children, and better asthma management skills…
- Trial name
- ChildAsthma (NCT02602392)
- Testing
- Lungtropolis, Asthma educational booklet
- Where
- United States
- Volunteers
- 622 people, healthy volunteers welcome
- Sponsor
- Oregon Center for Applied Science, Inc.
Gastrointestinal Dysfunction
Use of High Resolution Colonic Manometry in Studying Motility
An injury to the spinal cord (SCI) results in numerous medical complications, including gastrointestinal (GI) function. Individuals with SCI may experience severe constipation (prolonged stool retention), incontinence…
- Trial name
- NCT02574611
- Testing
- Neostigmine, Glycopyrrolate, High Resolution Colonic Manometry
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Abdominal Wall Hernia, Pancreatic Diseases
IV Acetaminophen for Post-Operative Pain Management in Enhanced Recovery After Surgery (ERAS) Population
Number of patients with unsatisfactory pain relief defined as average visual analog scale (VAS) more than 5 with or without requirement of IVPCA for pain relief during the first 48 hours postoperative period will be compared…
- Conditions
- Abdominal Wall Hernia, Pancreatic Diseases, Bowel Disease, Gastric Disease
- Trial name
- NCT03198871
- Testing
- Acetaminophen Injectable Product, Sodium Chloride 0.9%, Intravenous
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Kathirvel Subramaniam
Arthritis, Gout
Phone-Based Based Walk With Ease Program for Adults With Arthritis
The objective of this study is to examine the short-term (6-weeks and 6 months) and long-term (1 year) effects of a phone-based version of Walk With Ease intervention.
- Conditions
- Arthritis, Gout, Fibromyalgia, Rheumatoid Arthritis
- Trial name
- NCT05289544
- Testing
- Phone-Based Walk With Ease
- Where
- United States
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Schizophrenia
Role of Antioxidants (Vitamin C and E) in the Management of Schizophrenia
Background: Antioxidants are substances that are considered as a defensive material which protects cells from destruction. It is evident that use of food stuff rich in antioxidant will fortify one's ability to encounter with…
- Trial name
- NCT04078048
- Testing
- Antioxidants (Vitamin C, E )
- Where
- Pakistan
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Health Sciences Lahore
Pain
Non-pharmacological Pain Management in Term Neonates
A randomised clinical trial in a single centre. This study was performed to compare the effect of white noise, facilitated tucking, and their concerted application during heel-stick sampling on pain in term babies.
- Trial name
- NCT04144543
- Testing
- White Noise, Facilitated Tucking, White Noise+Facilitated Tucking
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Amount of NKTR-118 in Blood, Variation in the Heart's Electrical Cycle
A Placebo-controlled Four Way Crossover Study to Asses the Effect of a Single Oral Dose of NKTR-118 on QTc Interval in Healthy Male Subjects
The purpose of this study is to evaluate the effects on QTc interval in healthy males when administered a single dose of NKTR-118 compared with placebo and moxifloxacin.
- Trial name
- NCT01325415
- Testing
- NKTR-118, moxifloxacin
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Infertility
Co Administration of GnRH Agonist and hCG for Final Oocyte Maturation
All the studies, demonstrating improved oocyte maturity and high pregnancy rate with the dual trigger are all retrospective. The investigators therefore aim to perform a prospective randomized controlled study in normal…
- Trial name
- NCT02703584
- Testing
- Buseralin, pregnyl
- Where
- Canada
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Genital Diseases, Female, Ovarian Neoplasms
Pharmacokinetic Study on the Administration of Nadroparin Dosing Serum HGF in Gynecological Patients
The purpose of this study is to determine whether HGF serum concentration might be raised in vivo by administering nadroparin given with prophylactic purpose to gynecological patients.
- Conditions
- Genital Diseases, Female, Ovarian Neoplasms, Urogenital Neoplasms
- Trial name
- NCT01523652
- Where
- Italy
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera San Giovanni Battista
Caries
Post-operative Pain and Child Behavior of Hall Technique Versus SDF in the Management of Carious Primary Molars: RCT
PICO question: Papulation: children suffering from caries Intervention: Silver Diamine Fluoride Comparison: Hall technique Outcome: Primary Outcome: Intraoperative and postoperative pain Measurement device: Face pain scale…
- Trial name
- NCT04794426
- Testing
- Silver diamine fluoride, Hall Technique
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Noura Mohamed Alhosaini
Type2 Diabetes
A Study to Investigate the Bioequivalence Test of DA-1229_01(A) at Fed State
A study demonstrates the bioequivalence of DA-1229_01(A) at Fed State when compared with Sugamet sustained-release(SR) Tab 5/1000mg® in healthy adults
- Trial name
- NCT03944200
- Testing
- DA-1229_01(A), Sugamet SR Tab 5/1000mg®, Sugamet SR Tab 5/1000mg®, DA-1229_01(A)
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dong-A ST Co., Ltd.
Pediatric Anesthesia, Low Level Laser Theraphy
Efficacy of Low Level Laser Therapy on İnjection Pain
The purpose of this study was to compare the pain during needle insertion and injection in supraperiosteal anesthesia with either topical anesthesia (control) or LLTT (experimental).
- Trial name
- NCT04243811
- Testing
- Diode Laser, topical anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Okan University
Satisfaction
Prospective Trial of the TriFit™ Web Knee Brace
This is a prospective trial comparing improvements in pain, function, and quality of life in patients with early-stage knee osteoarthritis conservatively managed with the TriFit™ Web Knee Brace.
- Trial name
- NCT03633071
- Testing
- Web-knee brace
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Foundation for Orthopaedic Research and Education
Chronic Shoulder Pain, Rotator Cuff Related Shoulder Pain
HIIT for Inflammatory-driven Shoulder Pain.
This feasibility study investigates whether high-intensity interval training (HIIT) is feasible and acceptable for individuals with long-term shoulder pain where low-grade inflammation is suspected.
- Conditions
- Chronic Shoulder Pain, Rotator Cuff Related Shoulder Pain, Frozen Shoulder, Shoulder Adhesive Capsulitis
- Trial name
- NCT07275164
- Testing
- High intensity interval training (HIIT)
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Ageing
Ageing and Acute Care Physicians' Performance
The proportion of older acute care physicians (ACPs) has been increasing. Ageing is associated with physiological changes and research investigating how such age-related physiological changes affect clinical performance is…
- Trial name
- NCT02683447
- Testing
- CRM Simulation
- Where
- 2 sites in Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
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