Clinical trials: Management
Drug Drug Interaction
Drug-Drug Interaction Study of Intravenous Administration of SyB V-1901 and Cyclosporine in Japanese Healthy Subjects
To evaluate the effect of coadministered cyclosporine on the pharmacokinetics of brincidofovir following simultaneous administration of SyB V-1901 with cyclosporine, or coadministration of cyclosporine at 2 hours after the…
- Trial name
- NCT04542252
- Testing
- SyB V-1901, Cyclosporine
- Where
- Japan
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- SymBio Pharmaceuticals
Kidney Failure, Chronic, Renal Insufficiency, Chronic
A Study of LY2409021 in Participants With Different Levels of Kidney Function
The purpose of this study was to measure how much of the study drug, LY2409021, gets into the blood stream and how long it takes the body to get rid of it when given to participants with different levels of kidney function.
- Trial name
- NCT01929109
- Testing
- LY2409021
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Obesity
Effect of Diltiazem Administration on CP-945,598 Pharmacokinetics
A recently completed clinical drug interaction study of CP-945,598 with ketoconazole, a potent CYP3A inhibitor, showed that coadministration of CP-945,598 with ketoconazole results in an approximately 5-fold increase in…
- Trial name
- NCT00645463
- Testing
- CP-945,598
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Pfizer
Opioid Overdose
Naloxone Nasal Spray Pharmacokinetic Study
This study aims to compare the pharmacokinetics of naloxone when administered as the Mitovie nasal spray (Test Product) and as a solution for injection (Comparator Product) administered intranasally using a mucosal atomization…
- Trial name
- NCT01622504
- Testing
- MVP005, Naloxone hydrochloride solution for injection with mucosal atomization device
- Where
- Jordan
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Mitovie Pharma Ltd
Pulmonary Hypertension, Nursing Care
Dynamic Mixed Learning Module in Pulmonary Hypertension Patients
This study was conducted to evaluate the effect of the Dynamic Blended Learning Module developed for patients diagnosed with pulmonary hypertension (PH) on symptom management.
- Conditions
- Pulmonary Hypertension, Nursing Care, Learning
- Trial name
- Learning (NCT07429552)
- Testing
- Symptom Management
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Healthy
AME Study of [14C]-YH4808 in Healthy Male Subjects
The purpose of this study is to determine the absorption, metabolism, and excretion (AME) kinetics of YH4808 and to determine and characterize metabolites present in plasma, urine, and feces in man following a single dose of…
- Trial name
- NCT01825707
- Testing
- [14C]-YH4808 200 mg
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Yuhan Corporation
Shoulder Injury Related to Vaccine Administration, Erosion, Localized
Ultrasound and Immunological Findings in Patients With Shoulder Injury Related to Vaccine Administration (SIRVA)
Accidental vaccine injection into adjunct shoulder structures can cause tissue damage, termed Shoulder injury related to vaccine administration (SIRVA). The immunopathological mechanisms and consequences of SIRVA are unknown.
- Trial name
- SIRVA (NCT04236193)
- Testing
- Ultrasound Shoulder and Immunological Phenotyping by FACS
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Pain, Procedural, Pain, Acute
Effect of Reflexology on Pain Management in Newborns
Introduction: Approximately 10-14 painful procedures per day are performed in preterm and term infants during the hospital stay in the first week.
- Conditions
- Pain, Procedural, Pain, Acute, Analgesia
- Trial name
- NCT05235893
- Testing
- Reflexology, Sucrose %24, Kangaroo care
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Marmara University
Healthy
Tolerability and Pharmacokinetics of Lacidipine With and Without the Co-administration of Telmisartan in Female and Male Healthy Subjects
The objectives of this study are to compare the steady state pharmacokinetics of lacidipine with and without the co-administration of telmisartan and to compare the steady state pharmacokinetics of telmisartan with and without…
- Trial name
- NCT02203500
- Testing
- Lacidipine, Telmisartan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Volunteers
Feasibility of Upskilling Non-Radiology Personnel in X-ray
The goal of this feasibility study is to learn if individuals without formal radiology training can safely acquire adequate x-ray images following a structured training and real-time remote guidance from a licensed radiologic…
- Trial name
- NCT07713563
- Testing
- X-ray Operator Training
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Breast Neoplasm
CanRestoreFunction Cancer-related Fatigue ( CRF )
The goal of this randomized control trial is to determine if participating in an 8-week online cancer-related fatigue management intervention consisting of individualized exercise program, one-on-one goal setting and action plan…
- Trial name
- CRF (NCT05868187)
- Testing
- Exercise, Problem-Solving Session and Education
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Healthy
Pergoveris FD and Liquid China BE Study
The main purpose of this study is to assess the bioequivalence (BE) of the fixed combination of follitropin alfa and lutropin alfa in Pergoveris freeze-dried (FD) (Test 1) or in Pergoveris Liquid (Test 2) versus the…
- Trial name
- NCT04899193
- Testing
- Pergoveris FD, Pergoveris Liquid, Gonal-f
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Musculoskeletal Diseases or Conditions, Musculoskeletal Pain
Stress and Musculoskeletal Health in Employees
This study aims to evaluate potential correlation of stress as estimated by certain biological markers, namely saliva cortisol, Heart rate variability (HRV), Electromyography (EMG) with musculoskeletal system health status, and…
- Conditions
- Musculoskeletal Diseases or Conditions, Musculoskeletal Pain, Musculoskeletal Health, Stress
- Trial name
- MUStress (NCT06488547)
- Testing
- Diaphragmatic breathing (DF), Progressive Muscle Relaxation (PMR)
- Where
- 2 sites in Greece
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Psychological Distress
Mindfulness Training for Stress Management
This study will assess the short and long term effects of a group-based mindfulness programme (Mindfulness-Based Stress Reduction, MBSR) on first year medical and psychology students at the Universities of Oslo and Tromso.
- Trial name
- NCT00892138
- Testing
- Mindfulness training
- Where
- 2 sites in Norway
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Norwegian Knowledge Centre for the Health Services
18 Years and Over, Newborn Health
Multıdımensıonal Effects Of Delayed Cord Clampıng and Mılkıng on Placental Processes
This study was conducted to evaluate the effects of delayed cord clamping and milking the umbilical cord of term babies after 90 seconds during vaginal birth on the newborn and the mother and to determine whether it is a suitable…
- Conditions
- 18 Years and Over, Newborn Health, 37 or More Completed Weeks of Gestation
- Trial name
- DCC&MILKHEM P (NCT06865391)
- Testing
- Delayed cord clamping
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Thyroidectomy
Optimal Concentration of Remifentanil for NIM Tube Intubation With Low-dose NMBA
During thyroid surgery, Intraoperative Neuromonitoring (IONM) plays a crucial role in preventing serious complications such as bilateral vocal cord paralysis.
- Trial name
- NCT06162390
- Testing
- Remifentanil
- Where
- South Korea
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Kyungpook National University Chilgok Hospital
Chemotherapy-induced Neutropenia
A Safety and PK Study of EC-18 in Healthy Subjects
The purpose of this study is to determine if EC-18 is safe and tolerable in healthy subjects.
- Trial name
- NCT02496143
- Testing
- EC-18
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Enzychem Lifesciences Corporation
Arthritis
A Comparison of the ASHC and CDSMP
The arthritis-specific Arthritis Self Help Course (ASHC) and the more generic Chronic Disease Self Management Program (CDSMP) teach generalizable skills for managing arthritis and other chronic diseases.
- Trial name
- NCT00207415
- Testing
- ASHC and CDSMP
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
One-day Training Simulation With 4 Immersive Scenarios
Comparison of Learning Outcomes Between the Roles of Learner During an Immersive Simulation
The use of simulation in medical education has been associated with positive results in the acquisition of knowledge, skills, behaviors and in patient outcome.
- Trial name
- NCT02804425
- Testing
- actor-spectator
- Where
- France
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Université Paris-Sud
Toxic; Thyroid
Preoperative Administration of Lugols Solution in Toxic Thyroid Diseases (TD): A Prospective Study
Lugol's solution and other preparations containing iodide have been used as an adjuvant treatment in patients with toxic disease planned for thyroidectomy.
- Trial name
- NCT06176976
- Testing
- Lugol's iodine solution 5%
- Where
- Greece
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki