Clinical trials: Management
Postoperative Pain
Effects of Perioperative Administration of Intravenous Lidocaine in Children Operated on for Acute Generalized Peritonitis
Intravenous administration of lidocaine perioperatively after laparotomy for peritonitis could be an interesting alternative by reducing the duration of postoperative ileus, the intensity of pain and the patient's hospital stay…
- Trial name
- NCT06051630
- Testing
- Lidocaine intravenous, Serum saline intravenous
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Université NAZI BONI
Healthy Volunteers
Drug-drug-interaction Study of Ramipril, Amlodipine and Atorvastatin
Study to determine the potential pharmacokinetic interaction of ramipril (and ramiprilat), atorvastatin as atorvastatin calcium trihydrate and amlodipine as amlodipine besilate at steady state after a multiple oral administration…
- Trial name
- NCT04262765
- Testing
- Ramipril, Amlodipine and Atorvastatin
- Where
- Jordan
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Midas Pharma GmbH
Waste Management, Food Supply
FoodImage 3 Laboratory
The Laboratory Study will be conducted at PBRC and will include participants (N=25) from a wide array of social and economic groups will be recruited and trained on the use of the FoodImage app.
- Trial name
- FI3Lab (NCT06030700)
- Testing
- Controlled Conditions
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Placenta Previa
Management Of Placenta Previa Cases And Determination Of Hospitalization Criteria
Placenta previa cases are one of the difficult groups of patients to manage in modern obstetrics. When the literature is evaluated extensively, no clear information can be seen especially in terms of hospitalization time.
- Trial name
- NCT04264234
- Testing
- Vaginal Ultrasonography, Magnetic Resonance Imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Ege University
Chronic Periodontitis
Effect Of A Locally Delivered Probiotic Sacchraomyces Boulardii In The Management Of Chronic Periodontitis
This study was carried out in the Department of Periodontology and source of patient was be from the outpatient section of Tatyasaheb Kore Dental College \& Research Centre, New Pargaon.
- Trial name
- NCT03516370
- Testing
- Saccharomyces Boulardii 250 MG
- Where
- India
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Healing
Evaluation of Preferences of Consumers and Clinicians for the Management of Shave Biopsy Sites With a PolyMem Formulation Dressing or Current Standard of Care.
Shave biopsies are often uncomfortable during the healing process. This is a preliminary study to determine if patients and clinicians prefer using PolyMem formulating dressings on shave biopsy sites compared to the current…
- Trial name
- NCT00727870
- Testing
- Shapes by PolyMem dressing, Shapes by PolyMem Silver Dressing, Shapes by PolyMem on one site and Shapes by PolyMem Silver dressing on second site
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ferris Mfg. Corp.
Healthy, Pharmacokinetics of ASP015K and Tacrolimus
A Study to Evaluate the Drug Interaction of ASP015K and Tacrolimus
The objective of the study is to characterize the effect of multiple doses of ASP015K on the pharmacokinetics of a single oral dose or a single intravenous (IV) dose of tacrolimus.
- Trial name
- NCT01190670
- Testing
- Tacrolimus, ASP015K
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Healthy
A Clinical Trial to Evaluate the Pharmacokinetics and Safety of SIPS-2209-1 in Healthy Korean Volunteers
The goal of this clinical trial is to evaluate of bioequivalence between fixed-dose combination and co-administration of the individual components under fasting conditions in healthy Korean volunteers.
- Trial name
- NCT05787873
- Testing
- SIPS-2209-1, SIPS-2209-2, SIPS-2209-3
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samik Pharmaceutical Co. Ltd.
Pain
Defense and Veterans Center for Integrative Pain Management (DVCIPM) Pain Registry Biobank
This Pain Registry Biobank is a prospective cohort design study whereby data (PASTOR survey, blood and saliva specimens, clinical data) is collected from participants in a longitudinal fashion with continual enrollment.
- Trial name
- PRBiobank (NCT04004286)
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Dental Anxiety, Dental Fear
Comparing Augmented Reality and Virtual Reality Glasses to Help Children Feel Less Pain and Anxiety During Local Anesthesia
The goal of this clinical trial is to learn if audio-visual method of distraction is useful to control the pain and fear associated with dental treatment in children.
- Conditions
- Dental Anxiety, Dental Fear, Dental Fear and Anxiety
- Trial name
- NCT07060170
- Testing
- Augmented Reality Glasses, Virtual Reality Glasses
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riham Abbas
Chronic Inflammation of Appendix
Laparoscopic Versus Open Appendectomy
comparison between laparoscopic and open appendectomy in the management of chronic appendicitis
- Trial name
- NCT04618666
- Testing
- laparoscopic and open surgery intervention
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Mental Stress, Stress
Addressing Stress Among Women Entrepreneurs in Ethiopia - Scale up
The objective of this study is to examine the impact of the "Doing What Matters in Times of Stress" guided self-help handbook, along with phone-based lay helpers sessions, on the psychological well-being, business performance…
- Conditions
- Mental Stress, Stress, Stress, Job, Emotion Regulation
- Trial name
- NCT05888272
- Testing
- Stress managment
- Where
- Ethiopia
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- World Bank
Healthy Volunteers, Brain Excitation
Methods to Enhance Transcranial Direct Stimulation (tDCS)
tDCS has been shown to be an effective treatment for depression. However, tDCS is a relatively new clinical tool and more needs to be understood about its use.
- Trial name
- NCT01135953
- Testing
- Transcranial Direct Current Stimulation (tDCS), Transcranial direct Stimulation (tDCS) and D-cycloserine
- Where
- Australia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The University of New South Wales
Cushing Syndrome, Primary Aldosteronism
Continuous Steroid Monitoring in Interstitial Fluid With Wearable and Nanoparticle-enhanced Biosensors for Improved Management of Adrenal Disorders
The goal of this project is to provide novel technology that will pave the way from the present single-point (analogue) endocrinology towards continuous cortisol and aldosterone monitoring with full time resolution.
- Conditions
- Cushing Syndrome, Primary Aldosteronism, Adrenal Insufficiency
- Trial name
- NCT06980753
- Testing
- Participants will use the biossensor for 48 h
- Where
- Brazil
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Healthy
Bioequivalence of Metformin Under Fed Conditions After Administration of Linagliptin / Metformin Fixed Dose Combination Tablet and Single Tablets
To establish bioequivalence (BE) under fed conditions between metformin in linagliptin/metformin fixed dose combination tablet and metformin reference product administered in free combination togther with linagliptin
- Trial name
- NCT01581931
- Testing
- Linagliptin/metformin, Metformin, Linagliptin
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Adverse Effect of Antithrombotic Drugs
Study of Platelet Function After Administration of Aspirin Versus Lysine Acetylsalicylate
This is a phase I clinical trial in healthy volunteers comparing the effect of lysine acetylsalicylate or aspirin on platelet function.
- Trial name
- ECCLIPSE (NCT02243137)
- Testing
- acetylsalicylic acid, prasugrel, lysine acetylsalicylate
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- David Vivas
Healthy Participants
A Study Testing the Safety and Effects of Single Doses of S1-221 in Healthy Volunteers
The purpose of this Phase 1 study is to evaluate the safety, tolerability, and pharmacokinetics (PK) profile of single ascending doses of S1-221 administered orally to healthy adult participants.
- Trial name
- NCT07146945
- Testing
- S1-221, THC
- Where
- Australia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Delphian Therapeutics Australia Pty, Ltd
Major Depressive Disorder
Study to Assess the Distribution, Metabolism and Excretion of [14C]AZD6765 After a Single-Dose Intravenous Administration
This is a study to assess the distribution, metabolism and excretion of [14C]AZD6765 after a single-dose intravenous administration.
- Trial name
- AZD6765 (NCT01217645)
- Testing
- 150 mg [14C] AZD6765
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Cardiovascular Diseases, Stress, Psychological
Adaptive Internet-based Stress Management Among Adults With a Cardiovascular Disease: A Pilot Sequential Multiple Assignment Randomized Trial (SMART) Design
Internet-based stress management programs adapted to patients' needs Stress is inevitable, and it has many negative consequences on the health of everybody, but particularly on the health of patients with a cardiovascular disease…
- Trial name
- NCT03267953
- Testing
- My Health CheckUp Online Stress Management Program, Lay telephone coaching, Motivational interviewing (telephone)
- Where
- Canada
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- St. Mary's Research Center, Canada
Cow Milk Allergy, Tolerance
Testing Tolerance in Cow Milk Protein Allergy Patients: Milk Ladder or Direct Milk Administration?
Majority of children outgrow their allergies, however there are two different methods to re-introduce milk products in the infant diet either direct milk intake in escalating doses or milk ladder, starting with baked milk…
- Trial name
- NCT05960045
- Testing
- Direct Milk antigen reintroduction, Milk ladder
- Where
- Egypt
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.