Clinical trials: Management
Gestational Diabetes Mellitus
Gestational Diabetes in Central Asia: Prevalence and Management
Evaluate prevalence and management of gestational diabetes in Tajikistan in two different settings (one rural and one urban).
- Trial name
- GESDICA (NCT02436551)
- Testing
- Observation
- Where
- Germany
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Healthy Adult Subjects
A Itraconazole Effect Study of SHR2554 on Healthy Chinese Adult Subjects
The primary objective of the study is to evaluate the effect of Itraconazole on pharmacokinetics of healthy Chinese adult subjects after oral administration of SHR2554 tablets.
- Trial name
- NCT04627129
- Testing
- SHR2554 and Itraconazole
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Healthy
A Study to Assess the Absorption, Metabolism, and Routes of Excretion Following Oral Administration of (14C) Radiolabeled JNJ--42756493 to Healthy Male Participants
The purpose of this study is to assess the absorption, metabolism, and excretion of JNJ-42756493 in healthy male adult participants after administration of a single oral dose of 12 milligram (mg) of unlabeled JNJ-42756493 admixed…
- Trial name
- NCT02692677
- Testing
- JNJ-42756493
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Cardiac Arrest
Discover In-Hospital Cardiac Arrest
The Discover In-Hospital Cardiac Arrest (IHCA) study is a multicenter, prospective observational study aimed at better understanding variations in practice for the post-in-hospital cardiac arrest patient.
- Trial name
- Discover IHCA (NCT06207201)
- Where
- United States
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Intratracheal Intubation, Laryngoscopes
Incidence of Sore Throat With Traditional Intubation Blades or Glidescope Blade
The purpose in this study is to determine whether there is a difference in the incidence of postoperative sore throat when using the GlideScope™ versus a traditional intubation blade involving patients that are not anticipated to…
- Conditions
- Intratracheal Intubation, Laryngoscopes, Postoperative Care, Risk Assessment
- Trial name
- NCT02033564
- Testing
- Macintosh/Miller Laryngoscope, Glidescope Laryngoscope
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Jason Ngo, B.S.
Myocardial Infarction, Angina Pectoris
Improving Intermediate Risk Management. MARK Study
Cardiovascular risk functions fail to identify more than 50% of patients who develop cardiovascular disease. This is especially evident in the intermediate-risk patients in which clinical management becomes difficult.
- Conditions
- Myocardial Infarction, Angina Pectoris, Stroke, Peripheral Arterial Disease
- Trial name
- MARK (NCT01428934)
- Where
- Spain
- Volunteers
- 2,495 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Genuine Stress Incontinence
Prospective Study of Altis System With the TVTO Procedure for the Management of Stress Urinary Incontinence in Women
Prospective randomized comparison of minisling (altis) with the TVTO procedure for the management of women with genuine stress urinary incontinence.
- Trial name
- NCT03515109
- Testing
- Altis tape, TVTO
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aretaieio Hospital
Novice Teen Driver Training
An Evaluation of a Web-based Intervention Program for Parents and Teens to Promote Safe Driving
The long-term goal of this research is to increase safe driving among novice teen drivers by increasing the quantity, quality and diversity of driving practice while accompanied by an adult.
- Trial name
- NCT01498575
- Testing
- Teen driving plan
- Where
- United States
- Volunteers
- 1,024 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Dysmenorrhea, Menstruation Disturbances
Continuous Use of the Contraceptive Patch and the Personal Economic Impact.
Dr. Eleanor Drey in the Department of Obstetrics, Gynecology and Reproductive Sciences UCSF is conducting a study to examine the personal and economic impact of continuous use of ORTHO EVRA, the contraceptive patch, on menstrual…
- Conditions
- Dysmenorrhea, Menstruation Disturbances, Menstruation Disorders
- Trial name
- NCT00357981
- Testing
- ORTHO EVRA, the contraceptive patch
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Healthy
Healthy Volunteers Study to Estimate the Effects of Food on the Bioavailability of Oxycodone and Naltrexone/6- Β -Naltrexol From a Extended Release Formulation of Oxycodone With Sequestered Naltrexone
The purpose of this study is to estimate the effects of food and of sprinkling ALO-02 pellets on applesauce on the bioavailability of oxycodone and naltrexone/6- beta-naltrexol from an extended release pellets-in-capsule…
- Trial name
- NCT01456507
- Testing
- ALO-02 (Oxycodone Naltrexone)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer
Pruritus
Study of Itch Control by VLY-686 in Healthy Volunteers After Intradermal Injections of Substance P
The purpose of this study is to test whether VLY-686 can prevent or reduce the itch and dermatological reaction observed after healthy volunteers are injected with Substance P in comparison with placebo.
- Trial name
- NCT01919944
- Testing
- VLY-686
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Vanda Pharmaceuticals
Gagging
Ear Plugs Versus Acupressure for Management of Severe Gag Reflex
The aim of this study is to evaluate the efficacy of two proposed non-invasive techniques: the ear plug technique and acupressure on the P6 point in reducing gag reflex during impression making and to assess patient's experience…
- Trial name
- NCT02938364
- Testing
- Earplugs, Acupressure
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Chronic Heart Failure, Diabetes Mellitus
Exploring Acceptance and Outcomes of an Online-based Self-management Support System in Chronic Illness
The aim of the USECARE project is to improve and test SENACA, an ICT-based self-management support system for chronically ill patients and informal caregivers. 60 end-users will be instructed to use SENACA for approx.
- Conditions
- Chronic Heart Failure, Diabetes Mellitus, Chronic Obstructive Pulmonary Disease, Special Orthopaedic Co-Morbidity After Hip/Knee Replacement
- Trial name
- USECARE (NCT02832739)
- Testing
- SENACA - ICT based self-management support system
- Where
- 2 sites in Israel, Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assuta Medical Center
General Anesthesia
Comparison of the Effects of Dexmedetomidine and Lidocaine on Blood Pressure and Heart Rate Response
Endotracheal intubation is considered a definitive therapy and the gold standard for airway management. However, this procedure carries several risks, including sudden increases in blood pressure and heart rate.
- Trial name
- NCT06573957
- Testing
- Dexmedetomidine, Lidocain
- Where
- Indonesia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Dental Implant-Abutment Designs, Marginal Bone Loss in Different Abutment Designs
Peri-implant Tissues Changes for Different Abutment Shapes and Heights
The goal of this randomized clinical trial is to investigate the influence of supracrestal soft tissue on abutments of different heights (2-mm vs. 3-mm) and shapes (cylindrical abutment vs.
- Conditions
- Dental Implant-Abutment Designs, Marginal Bone Loss in Different Abutment Designs, Soft Tissue Management in Subcrestal Dental Implants
- Trial name
- NCT07509281
- Testing
- Bone-Level Implant Placement with Transmucosal Abutment and One Abutment-One Time Protocol
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Healthy
A Study in Healthy Men to Test How BI 685509 is Processed in the Body
The main objective of Part A is to investigate basic pharmacokinetics of BI 685509 and total radioactivity, including mass balance, excretion pathways and metabolism following administration of BI 685509 to healthy male subjects.
- Trial name
- NCT05515328
- Testing
- [¹⁴C] BI 685509 formulation 1, [¹⁴C] BI 685509 formulation 2, BI 685509 formulation 3
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Subjects
To Evaluate the Cardiac Safety and PK Following a Single Oral Dose Administration of Pacritinib in Healthy Subjects
The primary objective is to evaluate the cardiac safety of a single oral dose (400 mg) of pacritinib compared to placebo on the QT calculated using the Fridericia correction (QTcF) interval in healthy subjects.
- Trial name
- NCT02807207
- Testing
- A: pacritinib, C: moxifloxacin
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- CTI BioPharma
Placental Bleeding
Placental Drainage Versus no Placental Drainage After Vaginal Delivery in the Management of Third Stage of Labour
In this randomized controlled study, 222 pregnant women who admitted to Zeynep Kamil Women and Children's Health Training and Research Hospital from December 2016 and July 2017 were included.
- Trial name
- NCT03542292
- Testing
- placental drainage
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Platelet Aggregation
Loss of Effect of Aspirin on Platelet Aggregation During Chronic Administration
Aspirin has shown to be beneficial to some patients with certain diseases such as coronary artery disease or stroke. We are investigating how aspirin works on regulating platelets and thromboxane over time at different doses.
- Trial name
- NCT00748371
- Testing
- aspirin
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Malaria, Non-malarial Febrile Illness
Non-malarial Febrile Illness in Children in Areas of Perennial Malaria Transmission
To evaluate the causes of non-malarial febrile illness in children living in an area of perennial malaria transmission and to determine if these children who test negative for malaria by rapid diagnostic test receive any benefit…
- Trial name
- NCT01043744
- Testing
- Artemether-Lumefantrine
- Where
- 2 sites in Tanzania
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.