Clinical trials: Management
Healthy Volunteers
TAK-071 Scopolamine-Induced Cognitive Impairment Study
The purpose of this study is to assess the effect of a single oral dose of TAK-071 on the attenuation of cognitive deficit induced by scopolamine as measured by Groton Maze Learning Test (GMLT) (total number of errors).
- Trial name
- NCT02918266
- Testing
- Scopolamine, TAK-071, Donepezil
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Takeda
TMJ Disc Disorder, Treatment
Evaluation of the Effectiveness of Arthrocentesis Using Catheter in the Treatment of Temporamandibular Joint Disorders
The study focused on arthrocentesis performed using a catheter, aiming to assess its effects on pain perception and mouth opening in patients with TMJ disorders.
- Conditions
- TMJ Disc Disorder, Treatment, Arthrocentesis
- Trial name
- NCT06766851
- Testing
- Procedure: TMJ Arthrocentesis
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Healthy
Bioequivalence Study of UHAC62XX Tablets Compared With Capsules in Healthy Volunteers
Study to investigate the bioequivalence between 10 mg tablets (test drug) and 10 mg capsules (reference drug) of meloxicam (UHAC 62 XX) after 7-day administration.
- Trial name
- NCT02187575
- Testing
- UHAC 62 XX tablet, UHAC 62 XX capsule
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Hypotonic; Labor
Pharmacokinetics of Misoprostol With Titrated Oral Administration
The AUC240, AUC360, and AUC480 of titrated oral misoprostol are greater than traditional oral misoprostol.
- Trial name
- NCT01271257
- Testing
- Misoprostol
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Hepatitis B
A Study to Compare Blood Levels of Bepirovirsen and Safety Using Different Methods of Injecting in Healthy Adult Participants
This is an open-label study being done to compare two different methods of study medicine bepirovirsen is given in healthy adults.
- Trial name
- NCT07905157
- Testing
- Bepirovirsen
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Diabetes, Asthma
Integrated Care (IC) Models for Patient-Centered Outcomes
Multiple chronic conditions (MCC) are widely recognized as the U.S. public health challenge of the 21st century. These physical and behavioral health conditions take a large toll on those living with chronic diseases, including…
- Conditions
- Diabetes, Asthma, Chronic Obstructive Pulmonary Disease, Hypertension
- Trial name
- IC (NCT03451630)
- Testing
- High-Touch, High-Tech, Optimal Discharge Planning
- Where
- United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Tobacco Dependence
A Study of Novel Smoking Cessation Interventions in Current and Former Injection Drug Users
Cigarette smoking is very common in current and former injection drug users and is known to cause chronic lung diseases. Quitting smoking is proven to improve the health of people addicted to cigarettes. .
- Trial name
- NCT01334736
- Testing
- Usual care, Lung age, Contingency Management
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Stroke, Ischemic
Using SystemCHANGE™ to Enhance Medication Adherence in Older Adult Stroke Survivors
This study evaluated the feasibility and acceptability of using a SystemCHANGE intervention in older adult stroke survivors to improve medication adherence.
- Trial name
- NCT03211130
- Testing
- SystemCHANGE™, Attention-Control
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
SARS-CoV-2 Infection, Coronavirus Disease 2019 (COVID-19)
COVID-19: A Trial Studying the SARS-CoV-2 mRNA Vaccine CVnCoV to Learn About the Immune Response, the Safety, and the Degree of Typical Vaccination Reactions When CVnCoV is Given at the Same Time as a Flu Vaccine Compared to When the Vaccines Are Separately Given in Adults 60 Years of Age and Older
The most recently discovered coronavirus (SARS-CoV-2) may cause illness in humans ranging from the common cold to serious illness, also referred to as Coronavirus disease 2019 (COVID-19).
- Trial name
- CV-NCOV-011 (NCT04848467)
- Testing
- SARS-CoV-2 mRNA Vaccine (CVnCoV), Quadrivalent influenza vaccine (QIV)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bayer
Pelvic Pain, Infertility
Effect of the Bioheat Patch on Pain Following the HyFoSy Procedure
This randomized controlled trial (RCT) evaluates the efficacy of Bioheat thermal patches in reducing post-procedural pain following Hysterosalpingo Foam Sonography (HyFoSy).
- Conditions
- Pelvic Pain, Infertility, Pain Management, Gynecologic Procedures
- Trial name
- B-HyP (NCT07081971)
- Testing
- Bioheat Patch
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Healthy Adult Females
A Feasibility Study to Assess Tenofovir and Maraviroc Protection Against HIV-1 in Cervical and Vaginal Explants
The purpose of this study is to determine the feasibility of a novel method to assess antiretroviral efficacy for protection against HIV-1 infection in vaginal and cervical tissue biopsies.
- Trial name
- NCT02039323
- Testing
- Tenofovir, Maraviroc
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Chronic Low Back Pain
Laser and Therapeutic Ultrasound in the Management of the Chronic Non-specific Low Back Pain
The objective of this study is evaluate the laser and ultrasound effect on pain and disability in women with non-specific chronic low back pain.
- Trial name
- NCT02150096
- Testing
- continuous ultrasound group, pulsed ultrasound group, low level laser therapy group
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Healthy Male Volunteers
Food Effect Study of Anaprazole in Healthy Chinese Subjects
A single-center, randomized, open-labeled, 2×2 crossover phase 1 study to evaluate the pharmakinetics effect of high fat food to single dose administration of Anaprazole in healthy Chinese male subjects.
- Trial name
- NCT04463173
- Testing
- Anaprazole
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Sihuan Pharmaceutical Holdings Group Ltd.
Pain, Procedural
Oral Morphine Versus Ketamine in Pain Management
The study will mainly focus on procedural pain management using oral morphine versus rectal ketamine during paediatric burn and wound dressing at Mbarara Regional Referral Hospital.
- Trial name
- NCT05163366
- Testing
- GROUP A, GROUP B
- Where
- 2 sites in Uganda
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Mbarara University of Science and Technology
Hemodynamics of Cranial Arteries, Headache
The Hemodynamics Effect of Glibenclamide on Levcromakalim Assessed by High Resolution Magnetic Resonance Angiography (MRA) Technique in a Randomized Double-blind Cross-over Placebo-controlled Study With Healthy Volunteers
To investigate the effect of levcromakalim/placebo infusion on cranial arteries after glibenclamide administration.
- Conditions
- Hemodynamics of Cranial Arteries, Headache, Cerebral Blood Flow
- Trial name
- NCT03886922
- Testing
- Levcromakalim, Saline
- Where
- 2 sites in Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Mother's Anxiety, Child's Pain
The Study Aims to Determine the Effect of Using Animal-shaped Magic Mirrors During Vaccination in Children Aged 1-4 Years on the Child's Pain and the Mother's Anxiety.
Vaccination is one of the most common invasive procedures performed on healthy infants and children. These procedures can cause pain and fear in children and anxiety in parents.
- Trial name
- MAGİC MİRROR (NCT07535151)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Healthy
Study Comparing Pharmacokinetics of Different Formulations of Evobrutinib in Healthy Participants
The purpose of this study is to evaluate the pharmacokinetic (PK), pharmacodynamic (PD), and safety and tolerability of evobrutinib after oral administration of immediate release (IR) and modified release (MR) formulations in…
- Trial name
- NCT05245396
- Testing
- Ref (TF2), Evobrutinib MR-T1, Evobrutinib MR-T2
- Where
- United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Overactive Bladder
Over Active Bladder Patients Having Sling Surgery
The purpose of this study is to determine whether treatment with anti-muscarinic medications following sub-urethral sling procedures improves overall subjective and objective outcomes in women with mixed incontinence with primary…
- Trial name
- NCT00852696
- Testing
- Solifenacin
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Cleveland Clinic Florida
Molecular Mechanisms of Pharmacological Action, Depression
Effects of Acute Prucalopride Administration in Healthy Volunteers
This study will investigate whether administration of a single dose of the serotonin receptor subtype 4 (5-HT4) partial agonist prucalopride has effects on emotional processing and non-emotional cognition in healthy volunteers…
- Conditions
- Molecular Mechanisms of Pharmacological Action, Depression, Depressive Disorder, Mood Disorders
- Trial name
- NCT03863366
- Testing
- Prucalopride
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Tuberculosis
Safety and Risk of Sensitisation of the rdESAT-6 + rCFP-10 Skin Test Following Repeated Intradermal Administration
The primary objective is to assess the safety of three dose levels (0.01, 0.1 and 1.0 µg) of the rdESAT-6 + rCFP-10 skin test reagent when injected into healthy adults.
- Trial name
- NCT00793702
- Testing
- rdESAT-6 + rCFP-10
- Where
- Denmark
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Statens Serum Institut
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.