Clinical trials: Management
Influenza A (H1N1)
Observational Safety and Effectiveness Study of Adjuvanted Swine Origin A (H1N1) Pandemic Subunit Egg Derived Vaccine
This observational study will evaluate the safety and effectiveness following administration of adjuvanted Swine Origin A (H1N1) Pandemic Subunit Egg Derived Vaccine through both an ad hoc active monitoring system and a passive…
- Trial name
- NCT01101074
- Testing
- This is non-intervention observational study
- Where
- Italy
- Volunteers
- 135,469 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
TMJ Disc Disorder
Evaluation Lingual Ring Splint
To evaluate the effectiveness of Lingual Ring Splint For Management of Anterior Disc Displacement With Reduction
- Trial name
- NCT03000790
- Testing
- Lingual Ring Splint
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Schizophrenia
A Pharmacokinetic Study of Lurasidone After Single Oral Administration in Healthy Subjects
To evaluate the pharmacokinetic (PK) characteristics of lurasidone after single oral administration of different doses in healthy Chinese subjects.
- Trial name
- NCT02174510
- Testing
- 20mg lurasidone, 40mg lurasidone, 80mg lurasidone
- Where
- China
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Marubeni Pharmaceuticals (Suzhou) Co., Ltd.
Hypothermia
Intraoperative Warming Comparison of Devices
Hypothermia is a common and serious complication during anesthesia and surgery. Anesthetic-induced hypothermia results from the inhibition of thermoregulatory control and exposure to cold operating room environment.
- Trial name
- NCT00650260
- Testing
- Dynatherm Medical vitalHEAT Temperature Management System vH2, Bair Hugger™ (Arizant Healthcare, Eden Prairie, MN)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Medical Countermeasures, Organophosphate Poisoning
A Study to Evaluate the Intramuscular Administration of Scopolamine
To characterize the safety and tolerability profile of ascending doses of scopolamine hydrobromide trihydrate (Scopolamine HBT) administered by intramuscular (IM) injection.
- Trial name
- NCT04314713
- Testing
- Scopolamine Hydrobromide Trihydrate
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Battelle Memorial Institute
Metabolic Disorders, Non-alcoholic Steatohepatitis
A Study to Understand the Safety, Tolerability, and Activity of Drug in Body Over a Period of Time of AZD2693, in Subjects of Non-Childbearing Potential in Overweight But Otherwise Healthy Subjects, and Healthy Chinese and Japanese Subjects
This Phase 1, first-in-human (FiH), single-ascending-dose (SAD) study, will assess the safety and tolerability and characterize the pharmacokinetics (PK) of AZD2693, following subcutaneous (SC) SAD administration of AZD2693 in…
- Trial name
- NCT04142424
- Testing
- AZD2693
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy Volunteer
ENX-205 SAD/PET Study in Healthy Adults
This is a two-part study designed to evaluate the safety, tolerability, pharmacokinetics (PK), and receptor occupancy (RO) of ENX-205 in healthy adult participants in a double-blind placebo-controlled, single ascending dose (SAD)…
- Trial name
- NCT07253246
- Testing
- ENX-205
- Where
- United Kingdom
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Engrail Therapeutics INC
Brain Ischemia
A Feasibility Study for Randomization of Code Stroke Imaging Strategies
The purpose of this study is to test feasibility of a comparative effectiveness framework for acute stroke imaging using prospective electronic health data.
- Trial name
- CSI (NCT06270927)
- Testing
- MRI, CT
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Healthy Adults
Phase 1a Single Ascending Dose Study of MIB-725 in Healthy Adults
This is a single center, open label (i.e. participants and study staff will not be masked to the intervention) single ascending dose study to evaluate the safety, tolerability, pharmaokinetics and pharmacodynamics of MIB-725 in…
- Trial name
- NCT06815991
- Testing
- MIB-725
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Metro International Biotech, LLC
Hypertension Prevention and Management
Digital Health Platform Blood Pressure Management Study
This pilot study evaluated the effectiveness of an AI health education assistant compared to case manager support in hypertension management.
- Trial name
- NCT07147413
- Testing
- Behavioral/Digital Health Intervention
- Where
- Taiwan
- Volunteers
- 1,726 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Arthropathy of Hip
Supra-inguinal Fascia Iliaca Compartment Block on Postoperative Management in Total Hip Arthroplasty by Posterior Approach
Find the impact of supra-inguinal fascia iliaca compartment block on postoperative pain management after total hip arthroplasty by posterior surgical approach
- Trial name
- NCT04574479
- Testing
- Supra-inguinal fascia iliaca compartment block, Multimodal analgesia and PCA morphine pump
- Where
- Belgium
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Liege
Cervical Cancers, CIN - Cervical Intraepithelial Neoplasia
Primary HPV Self-Collection in Indonesia
The purpose of this study is to implement human papillomavirus (HPV) self-collection in Indonesia.
- Conditions
- Cervical Cancers, CIN - Cervical Intraepithelial Neoplasia, Human Papillomavirus (HPV)
- Trial name
- NCT06942286
- Testing
- HPV Self-Collection
- Where
- 3 sites in Indonesia
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Dharmais National Cancer Center Hospital
Hypertension
Continuing the Conversation: Using Narrative Communication to Support Hypertension Self-management in African American Veterans
In this study the investigators will conduct a randomized controlled trial aimed at improving hypertension self-management and lowering blood pressure (BP) in African-American Veterans.
- Trial name
- NCT03970590
- Testing
- CTC Intervention, Control
- Where
- 3 sites in United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Healthy
Safety and Pharmacokinetic Effects of Oseltamivir Alone or in Combination With Amantadine
This study is designed to assess the safety and pharmacokinetic effects of oseltamivir administration alone or in combination with amantadine in healthy volunteers.
- Trial name
- NCT00416962
- Testing
- amantadine hydrochloride, oseltamivir phosphate
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Novartis
Hepatitis B
A Study to Compare Blood Levels of Bepirovirsen and Safety Using Different Methods of Injecting in Healthy Adult Participants
This is an open-label study being done to compare two different methods of study medicine bepirovirsen is given in healthy adults.
- Trial name
- NCT07905157
- Testing
- Bepirovirsen
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy Volunteer
A Study of Safety, Pharmacokinetics (Including Food Effect) And Pharmacodynamics of RO5545965 in Healthy Volunteers
This randomized, Investigator/Subject-blind, adaptive single-ascending-dose, placebo-controlled, parallel study will evaluate the safety, tolerability, pharmacokinetics (including the effect of food), and pharmacodynamics of…
- Trial name
- NCT01711801
- Testing
- RO5545965
- Where
- Netherlands
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Healthy
A Drug Interaction Study of Cilnidipine and Valsartan
The investigators investigate the potential pharmacokinetic drug-drug interaction between Cilnidipine 10 mg and Valsartan 160 mg in healthy male volunteers who receive Cilnidipine 10 mg alone, Valsartan 160 mg , and both together…
- Trial name
- NCT01838967
- Testing
- C - V - C+V, C - C+V - V, V - C - C+V
- Where
- South Korea
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- IlDong Pharmaceutical Co Ltd
Analgesia Assessment
Bupivacaine Liposome Suspension Administration to Decreasre Peri-procedural Pain in Interventional Radiology (IR) Procedures
This study evaluates the use of liposomal bupivacaine (Exparel), a long-acting local anesthetic, for peri-procedural pain control in patients undergoing interventional radiology (IR) procedures.
- Trial name
- NCT07535411
- Testing
- Liposomal Bupivacaine (EXPAREL®)/Bupivacaine
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Children Born After Assisted Reproductive Technologies, Health Status
Health Status of Children Born After Assisted Reproductive Technologies
The goal of this observational study is to study the features of psychophysical development and the morbidity patterns of children born after assisted pregnancy, and to identify the connection with the health status of mothers…
- Conditions
- Children Born After Assisted Reproductive Technologies, Health Status, Child Development
- Trial name
- NCT06094998
- Testing
- hemogram examination
- Where
- Kazakhstan
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Kazakhstan's Medical University "KSPH"
Leadership Skills and Knowledge in Postgraduate Trainees
Growing Future Physician Leaders: A Randomized Trial of an Educational Intervention in Postgraduate Trainees
Study objective: The objective of this trial was to determine the effectiveness of a Leadership Development Program (LDP) aimed at 1) establishing basic management knowledge and 2) promoting reflection of leadership skills.
- Trial name
- NCT00286975
- Testing
- Leadership development program educational intervention
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
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