Clinical trials: Mandible Reconstruction
Operation Time, Complication of Surgical Procedure
CAS Versus Traditional Freehand Technique for Mandibular Reconstruction With Free Vascularized Fibular Flap
A total of 153 patients who underwent mandibular reconstruction by VFF were included from Jan 1999 to Dec 2019. The mandibular resection and reconstruction were performed by four experienced oral and maxillofacial surgeons.
- Trial name
- NCT04965441
- Testing
- Computer-assisted surgery
- Where
- Belgium
- Volunteers
- 153 people
- Sponsor
- KU Leuven
Mandibular Fractures, Mandible Fracture
Facial iD Customized Mandible Reconstruction Plates
A retrospective post market follow up to confirm the safety and performance of Stryker's Customized Plates for Mandibular Reconstruction.
- Conditions
- Mandibular Fractures, Mandible Fracture, Mandible; Deformity, MANDIBLE
- Trial name
- NCT07245758
- Testing
- Mandibular reconstruction
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stryker Craniomaxillofacial
Mandible Tumor
Mandibular Reconstruction Bone Plate
The purpose of this study is to evaluate the reliability of using mandibular osteosynthesis a 2.3mm reconstruction bone plate in the maintenance of the space, contour, and mandibular bone preservation during marginal mandibular…
- Trial name
- NCT06099431
- Testing
- Mandibular marginal resection and reconstruction, mandibular osteosynthesis a 2.3mm reconstruction bone plate
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Tanta University
Temporomandibular Joint Disc Displacement
Accuracy of Digital Mandibular Repositioning in Occlusal Reconstruction for Patients With Disc Displacement
This study evaluates a new, individualized treatment for adolescents with temporomandibular joint disorders (TMD) caused by bilateral, reducible disc displacement.
- Trial name
- NCT07345104
- Testing
- Clinical Clicking Elimination Repositioning Splint, Adjustable Articulator Repositioning Splint, CAD-Designed Anatomical Repositioning Splint
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Fujian Medical University
Neoplasm, Oral, Osteoradionecrosis of Jaw
Jaw Reconstruction With Printed Titanium and Free Tissue Transfer
JaW PrinT is a prospective observational cohort study evaluating the effectiveness of two different techniques of mandibular reconstruction.
- Conditions
- Neoplasm, Oral, Osteoradionecrosis of Jaw, Mandibular Diseases, Jaw Cancer
- Trial name
- JaW PrinT (NCT03905005)
- Testing
- Mandibular reconstruction with free tissue transfer.
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of South Wales
Mandible Tumor, Mandibular Injuries
Evaluation of EpiBone-CMF for Mandibular Ramus Reconstruction
EpiBone-Craniomaxillofacial (EB-CMF) is an autologous, anatomically shaped bone graft created specifically for the patient's defect, using the patients own adipose-derived mesenchymal stem cells.
- Conditions
- Mandible Tumor, Mandibular Injuries, Mandible; Deformity
- Trial name
- EB-CMF (NCT03678467)
- Testing
- EB-CMF
- Where
- 3 sites in United States
- Volunteers
- 6 people
- Sponsor
- Epibone, Inc.
Oropharynx Squamous Cell Carcinoma, Oral Cavity Squamous Cell Carcinoma
Study Comparing Fibula Free-flap MR With or Without PVP in Patients With OOPC
This is a national multicenter, randomized, stratified, open label study, aiming to compare mandibular reconstruction (MR) with or without preoperative virtual planning (PVP), in patients with oral/oropharyngeal cancer (OOPC).
- Trial name
- CURVE (NCT04725396)
- Testing
- Mandibular Reconstruction (MR) with Preoperative Virtual Planning (PVP)., Conventional Mandibular Reconstruction (MR without PVP)
- Where
- 10 sites in France
- Volunteers
- 132 people
- Sponsor
- UNICANCER
Bone and Joint Infection
Infection After Free Fibula Flap Reconstruction of the Mandible: a Retrospective Cohort Study
Mandibular osteitis after flap reconstruction is rare but is a serious infection with significant sequelae. The aim of this study is to describe this type of infection
- Trial name
- FibFlapI (NCT04373278)
- Testing
- failure of reconstruction of the mandibule by free fibula flap
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Benign or Malignant Tumour of the Oral Cavity, Stage III-IV Osteonecrosis
Validation of the O-bridge Protocol: a Prospective, Multicenter Trial
Surgical reconstruction to restore oral function and aesthetics after major ablative surgery in the oral cavity forms a challenge to maxillofacial surgeons, and greatly impacts patient' quality of life (QOL).
- Conditions
- Benign or Malignant Tumour of the Oral Cavity, Stage III-IV Osteonecrosis, Mandibular Reconstruction, Fixed Dental Restoration
- Trial name
- NCT04007783
- Where
- 5 sites in Belgium
- Volunteers
- 80 people
- Sponsor
- AZ Sint-Jan AV
Bone Augmentation
Reconstruction of Atrophic Maxillary Ridges Using Mandibular Blocks With and Without Coverage Using Collagen Membrane
Is the use of collagen membrane on top of particulate bone mixture covered by onlay bone block in Maxilla better than the use of mixture of particulate bone covered by onlay bone block without the use of collagen membrane, in…
- Trial name
- NCT04462575
- Testing
- Onlay bone block covered using collagen membrane, Onlay bone block without collagen membrane
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Head and Neck Cancer
Functional and Aesthetic Outcomes After Mandible Reconstruction With Fibula Osteomyocutaneous Free Flaps
The purpose of this study is to assess the functional and esthetic outcomes in patients who had removal of a part of the lower jaw bone due to mouth cancer and reconstruction of the jaw bone with a bone ( fibula) from the leg at…
- Trial name
- NCT02572869
- Testing
- physical exam, questionnaires
- Where
- 3 sites in United States
- Volunteers
- 26 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Jaw Deformity
Evaluation of "Tent-Pole" Grafting Technique for Reconstruction of Mandibular Ridge Vertical Defects
The aim of this study is to evaluate clinically and radio-graphically the efficiency of "Tent- Pole "grafting technique for reconstruction of anterior or posterior mandibular ridge defects using synthetic bone graft and Platelet…
- Trial name
- NCT04192851
- Testing
- Tent Pole Technique
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Nourhan M.Aly
Oral Surgical Procedures, Surgery, Oral
Standardized Osteotomy Guides for Free Flap Reconstruction of Continuous Defects of the Jaws - a Simplified Method
The aim of the present project is to evaluate the outcome from reconstruction of the jaws, with a standardized simplified technique, after a continuous defect.
- Conditions
- Oral Surgical Procedures, Surgery, Oral, Mandibular Reconstruction
- Trial name
- NCT05715359
- Testing
- Reconstruction
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Lund University Hospital
Mandibular Injuries
Virtual Surgical Planning of Mandibular Reconstruction Using Custom Made Plate and Split Rib Bundle Bone Graf
In mandibular reconstruction, computer-assisted procedures, including virtual surgical planning (VSP) and Custom-made implants, have become an integral part of routine clinical practice.
- Trial name
- NCT07551154
- Testing
- ustom made plate and split rib bundle bone graft using virtual surgical planning
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Mandibular Deficiency
Accuracy of Implant Placement for Patients With Mandibular Reconstruction Using Dynamic Navigation and Static Guides
To evaluate and compare the accuracy of implant placement using dynamic navigation technique versus static template technique in patients with bone tissue flap reconstruction of mandibular defects, thus further guiding the…
- Trial name
- NCT06250907
- Testing
- The guidance of dynamic navigation, The guidance of static template
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University