Clinical trials: Mandibular Diseases
Mandibular Dysfunction
Intramuscular Injections of Botulinum Toxin in Lateral Pterygoid Muscle in the Treatment of Temporomandibular Dysfunctions: Studying the Interest of MRI Guidance and Ultrasound Guidance
The main hypothesis is that a significant pain improve (measured with Visual Analogic Scale [VAS]) can be observed after injection of botulinum toxin A, meaning the success of the guidance device.
- Trial name
- MAUSBOT (NCT04900324)
- Testing
- MRI guidance, Ultrasound guidance
- Where
- France
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Pain, Virtual Reality
Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (VR TMD EEG)
This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia.
- Conditions
- Pain, Virtual Reality, Placebo, Temporomandibular Disorder
- Trial name
- VR TMD EEG (NCT06214923)
- Testing
- RelieVRx, No-VR (natural history control)
- Where
- 2 sites in United States
- Volunteers
- 78 people
- Sponsor
- University of Maryland, Baltimore
Mandibular Fractures, Facial Fracture
Stryker Facial iD Universal Plate Configurator: A Retrospective Post Market Follow Up
A retrospective post market follow up to confirm safety and performance of Stryker's Facial iD Universal Plate Configurator (UPC) implants in the clinical setting.
- Conditions
- Mandibular Fractures, Facial Fracture, Maxilla Fracture, Orthognathic Surgical Procedures
- Trial name
- UPC (NCT07245810)
- Testing
- Orthognatic surgery, Reconstructive maxillofacial surgery, Mandible and maxillofacial trauma surgery
- Where
- 2 sites in United States
- Volunteers
- 726 people
- Sponsor
- Stryker Craniomaxillofacial
Temporomandibular Joint Dysfunction
Electromyographic Evaluation of the Efficacy of Manual Therapy in Temporomandibular Joint Dysfunction.
Individuals with temporomandibular joint dysfunction (TMD) may experience changes in muscle activation as a result of symptoms such as pain and limitation of movement.
- Trial name
- NCT05420896
- Testing
- Manual Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Bahçeşehir University
Jaw, Edentulous
Evaluation of Dental Implants After Using Several Bone Splitting Techniques
In both complete and partial tooth loss, the use of dental implants as artificial replacements for missing teeth is a well-established and effective treatment modality, leading to high patient satisfaction and improved quality of…
- Trial name
- NCT05720143
- Testing
- Osseodensification, Magnetic mallet, Piezo-surgery
- Where
- Syria
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Damascus University
Impacted Tooth, Postoperative Complications in Maxillofacial Surgery
Effectiveness of Postoperative Topical and Oral Antibiotics on Impacted Mandibular 3rd Molar Surgery.
This randomized controlled trial evaluates the effectiveness of postoperative topical antibiotics compared with oral antibiotics in patients undergoing surgical extraction of impacted mandibular third molars.
- Conditions
- Impacted Tooth, Postoperative Complications in Maxillofacial Surgery, Surgical Wound Infection, Facial Pain
- Trial name
- POTA-M3S (NCT07573033)
- Testing
- Topical Antibiotic, Oral antibiotic therapy
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Liaquat College of Medicine and Dentistry
Mandible; Deformity, Surgical Healing
LLLT Effects on Inferior Alveolar Nerve (IAN) Recovery Post-orthognathic Surgery
Low-level laser therapy (LLLT) is a well-studied technique that has been shown to improve recovery time and reduce pain and swelling in patients undergoing surgery, including orthognathic surgery, and has no known negative…
- Conditions
- Mandible; Deformity, Surgical Healing, Orthognathic Surgery, Nerve Injury
- Trial name
- NCT04910074
- Testing
- Low-level laser therapy, Dummy LLLT
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Temporomandibular Disorders
Effects of the Use of Occlusal Splint on the Postural Balance of Individuals With Temporomandibular Disorder
To investigate the effects of the use of occlusal splint over postural balance in individuals with signs and symptoms of temporomandibular disorder.
- Trial name
- NCT02251015
- Testing
- occlusal plate, therapeutic exercises
- Where
- Brazil
- Volunteers
- 49 people
- Sponsor
- University of Sao Paulo
Temporomandibular Disorders (TMD), Bruxism
Behavioral Interventions for Controlling Oral Behaviors
Ecological momentary assessment (EMA) interventions via mobile devices can be implemented to monitor an individual's negative health behaviors in real-time, increase awareness, and assist patients in overting those behaviors.
- Conditions
- Temporomandibular Disorders (TMD), Bruxism, Masseter
- Trial name
- NCT07022795
- Testing
- Educational video combined with daily surveys, Educational video only
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Class II Division 1 Malocclusion
Mechanism of Class II Correction With Fixed Lingual Mandibular Growth Modificator (FLMGM)
The aim of the current controlled trial was to assess the possible net skeletal and dental effects of FLMGM treatment in relation to growth with emphasis on the contribution of skeletal and dental changes to sagittal correction…
- Trial name
- FLMGM (NCT01853995)
- Testing
- Fixed Lingual Mandibular Growth Modificator (FLMGM)
- Where
- Syria
- Volunteers
- 43 people
- Sponsor
- Damascus University
Low Level Laser Therapy, Temporomandibular Joint Disorders
The Efficacy of Low-level Laser Therapy (LLLT) as an Adjunct Treatment for Pain and Functional Outcomes in Temporomandibular Disorders (TMD)
The goal of this clinical trial is to evaluate the effectiveness of low-level laser therapy (LLLT) as an adjunct treatment in patients aged 18 years and older diagnosed with temporomandibular disorders (TMD).
- Conditions
- Low Level Laser Therapy, Temporomandibular Joint Disorders, Pain, Physical Therapy
- Trial name
- LLLT IN TMD (NCT07840495)
- Testing
- LLLT
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Chronic Periodontitis
Locally Delivered Atorvastatin & Rosuvastatin for Treatment of Furcation Defects in Chronic Periodontitis
Statins are one of the lipid lowering drugs that help in reducing cholesterol levels in the body by specifically inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase; which is a rate limiting enzyme for cholesterol…
- Trial name
- NCT02800902
- Testing
- Rosuvastatin, Atorvastatin
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Mandible Fracture
Accuracy of Computer Guided Screw Holes Locating Guide and Patient Specific Champy Plate vs Conventional Champy Plate Osteosynthesis in Management of Mandibular Angle Fracture: Randomized Controlled Trial
the aim of our study is to assess computer guided mandibular fracture reduction and to prove its lower rate of complications and higher accuracy of reduction compared to the conventional approach in management of mandibular angle…
- Trial name
- NCT06838377
- Testing
- standard Champy mini plate, computer guided screw holes locating guide and Patient Specific Champy plate
- Where
- 2 sites in Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
TMD/Orofacial Pain, Malocclusions
Evaluation of the Effects of Orthognathic Surgeries on the Temporomandibular Joint Using a Mandibular Movement Analyzer Device
Condylar position and mandibular motion assessment with digital facebows Arcus Digma III before and after orthognathic surgery.
- Trial name
- NCT07828041
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- Semmelweis University
Women, Osteoporosis
Temporomandibular Disorders and Osteoporosis
Increased life expectancy has attracted research attention, interested in provide a quality and healthy aging. According to the latest census conducted in 2010 by IBGE, Brazilian population consists of 97,342,162 women, whom…
- Conditions
- Women, Osteoporosis, Osteopenia, Temporomandibular Disorder
- Trial name
- TMDOST (NCT01029210)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Temporomandibular Joint Disorders
Laser Therapy on TMJ Disorders After Head and Neck Cancer.
Temporomandibular disorder (TMD) is a term describing musculoskeletal conditions of the face, jaw and temporal regions. TMD is frequently associated with pain and/or dysfunction such as impaired jaw function, pain in the…
- Trial name
- NCT05868460
- Testing
- High intensity laser, traditional physical therapy exercise program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Anxiety State, Pain
The Effect of Music and White Noise on Patients' Anxiety and Pain During Surgery for Impacted Mandibular Third Molar
The goal of this clinical trial is to evaluate the effect of music and whitenoise on the anxiety and pain level of patients who had impacted third molars surgery.
- Trial name
- NCT06814366
- Testing
- music and white noise intervention, music intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Necrotic Pulp
Postoperative Pain Following Treatment of Asymptomatic Necrotic Mandibular Molars in Single Visit Using Wave-one Reciprocating Instruments Versus One-Shape Rotary Instruments
The aim of this study is to evaluate the post treatment pain after instrumentation of root canals with a single file reciprocating (Wave-One Ni Ti file, DENTSPLY Maillefer) or rotary(One Shape, Micro Mega, France) file system in…
- Trial name
- NCT03301259
- Testing
- One-shape rotationary system
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Temporomandibular Disorder.
Effect of Phototherapy in Individuals With Temporomandibular Disorder.
The present study aims to evaluate the effect of phototherapy with the combination of different sources of light on pain, activity of temporal and masseter muscles, bilateral and joint mobility in subjects with TMD.
- Trial name
- NCT02018770
- Testing
- Phototherapy
- Where
- Brazil
- Volunteers
- 48 people
- Sponsor
- University of Nove de Julho
Obstructive Sleep Apnea (OSA), Mild Cognitive Impairment
CPAP vs MAD for OSA in Patients With Cognitive Impairment. A Randomized Clinical Trial
Obstructive sleep apnea (OSA) is a prevalent condition that significantly impacts the sleep health and overall well-being of millions of adults worldwide.
- Trial name
- CRESCENDO (NCT06983769)
- Testing
- MAD, CPAP
- Where
- Singapore
- Volunteers
- 260 people
- Sponsor
- National University Hospital, Singapore