Clinical trials: Mandibular Dysfunction
Temporomandibular Joint Disorders
Motor Cortex as a Research & Therapeutic Target in TMD
The investigators are doing a study to learn about the effects of a type of low-energy non-surgical electrical brain stimulation (HD-tDCS) on chronic pain in people's jaw joints.
- Trial name
- NCT02247063
- Testing
- High-Definition Transcranial Direct Current Stimulation (HD-tDCS)
- Volunteers
- 24 people
- Sponsor
- University of Michigan
Chronic Orofacial Pain, Temporomandibular Disorder (TMD)
Orofacial Pain Self-management: Personality Moderation Effect
The objective of this clinical trial is to study the effect of self-management on pain perception in patients with chronic orofacial pain and temporomandibular disorders (TMD) comparing it with the conventional treatment proposed…
- Conditions
- Chronic Orofacial Pain, Temporomandibular Disorder (TMD), Temporomandibular Disorders (TMD), Temporomandibular Dysfunction (TMD)
- Trial name
- NCT06932406
- Testing
- Self-management intervention, Clinical Practice Guideline Intervention
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
Temporomandibular Disorder, Oxidative Stress
Evaluation of Oxidative Stress and Inflammation Markers in Temporomandibular Disorders
Background: The occurrence of many diseases has been associated with oxidative stress and disruption of antioxidant mechanisms. Temporomandibular Joint(TMJ) Disorders are also thought to develop with the onset of the destructive…
- Conditions
- Temporomandibular Disorder, Oxidative Stress, Inflammation
- Trial name
- NCT05985733
- Testing
- Biochemical analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
TMJ Disorder
Condylar Position Changes in Anterior Disc Displacement with Reduction
the goal of this clinical trial is to know if TMJ lavage does change the condyle position in patients diagnosed with unilateral anterior disc displacement with reduction.
- Trial name
- NCT06856811
- Testing
- tmj lavage with ringer lactate solution
- Where
- Yemen
- Volunteers
- 14 people
- Sponsor
- Sana'a University
Temporomandibular Disorder, Neck Pain
How is Aerobic Exercise Compared to Localized Pain Relief Exercises in Patients With Jaw Pain and Neck Pain?
Musculoskeletal (MSK) disorders are some of the most burdensome health issues in the world and the leading causes of years living with a disability.
- Trial name
- NCT05232604
- Testing
- Aerobic exercise, Neck motor control exercise
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- Hochschule Osnabruck
TMJ Disorder
MESNA Injection for TMJ Internal Derangement
The pathogenesis of temporomandibular disorders focusing on the biochemistry of the synovial fluid in various stages of temporomandibular joint disease.
- Trial name
- NCT05882604
- Testing
- Mesna Injection, Arthrocentesis with ringer solution
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Temporomandibular Joint Dysfunction Syndrome, Tooth Injuries
Effectiveness of Three Oral Devices as Mouthguard in Electroconvulsive Therapy. Randomized Crossover Clinical Trial.
This observer-blind crossover intervention study aims to determine the most effective type of device as oral mouthguard in modified-Electroconvulsive Therapy (m-ECT) comparing three types of devices: standard, prefabricated and…
- Conditions
- Temporomandibular Joint Dysfunction Syndrome, Tooth Injuries, Dental Occlusion, Traumatic
- Trial name
- NCT02678715
- Testing
- Solubrux®, Customized Appliance, Somatics®
- Where
- Spain
- Volunteers
- 4 people
- Sponsor
- Eva Willaert Jiménez-Pajarero
Muscle Pain
Cocoa Intake and Muscle Pain Sensation
This experimental randomized, double-blind, and controlled study included fifteen young, healthy, and pain-free men and 15 age-matched women. It lasted for three visits with at least one-week washout.
- Trial name
- NCT05378984
- Testing
- before - hypertonic saline 5%, after - hypertonic saline 5%
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Temporomandibular Disorder
Comparison of the Effectiveness of Three Different Treatment Methods in Myofascial Pain Patients
The aim of this study was to compare the effectiveness of myofascial pain treatment methods.
- Trial name
- NCT03400462
- Testing
- NSAID, oral appliance, dry needling
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Temporomandibular Disorder
Investigation and Modulation of the Mu-opioid Mechanisms in TMD (in Vivo)
In this study, this team of researchers will investigate the impact of chronic temporomandibular disorder suffering on the endogenous μ-opioid system in vivo, arguably one of the principal endogenous pain modulatory systems in…
- Trial name
- NCT03724032
- Testing
- HD-tDCS*
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Temporomandibular Disorder (TMD), Bruxism
Temporomandibular Disorders and Bruxism in Elite Basketball Referees
This study aims to determine the frequency of temporomandibular disorders (TMD) and bruxism in elite basketball referees and to compare the findings with healthy controls.
- Trial name
- NCT07662486
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Styloid-Stylohoid Syndrome, Temporomandibular Disorder
Evaluation of Styloid Chain Calcification to the Patient With the Temporomandibular Joint Disorder
The aim of the study was to evaluate any relation between elongated styloid process (ESP) and type of Temporomandibular Joint Disorders (TMD).
- Trial name
- NCT04280107
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Nuh Naci Yazgan University
Temporomandibular Disorder, Orofacial Pain
An Open Label Study Assessing REN Treatment in Headache Management in Temporomandibular Disorders
Temporomandibular disorders (TMD) encompass a group of conditions involving the masticatory muscles, temporomandibular joint (TMJ), and associated structures.
- Trial name
- NCT07639944
- Testing
- Nerivio treatment
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- Theranica
Temporomandibular Joint Disorder
Optimizing Resilience In Orofacial Pain and Nociception
The purpose of this study is to examine the effects of a hope-based intervention on clinical and experimental pain in individuals with temporomandibular disorder (TMD).
- Trial name
- ORION (NCT02164630)
- Testing
- Hope Therapy, Pain Education
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Florida
Temporomandibular Joint Disorders, Temporomandibular Disorder
Stem Cells and Stromal Vascular Fraction for Temporomandibular Joint Disease
It will be evaluate the safety of mesenchymal stem cells and adipose tissue derived stromal vascular fraction (SVF) in temporomandibular joint disease cases.
- Conditions
- Temporomandibular Joint Disorders, Temporomandibular Disorder, Temporomandibular Joint Osteoarthritis, Temporomandibular Joint Pain
- Trial name
- NCT05305833
- Testing
- Stem Cells
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- TC Erciyes University
Central Nervous System Sensitization
Correlation Between Central Sensitization Inventory and Posturographic Data
To investigate the use of balance as a screening tool for Central Sensitization, a condition of the nervous system that is associated with the development and maintenance of chronic pain.
- Trial name
- NCT03058003
- Testing
- Posturography Evaluation, Central Sensitization Inventory
- Where
- 2 sites in United States, Australia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Caps Research Network
Temporomandibular Disorder
K23- Physical Self Regulation vs Placebo
This study will use a between-person design. Participants will be treatment-seeking patients with chronic masticatory muscle pain.
- Trial name
- NCT06357702
- Testing
- Physical Self Regulation Telehealth, Psycho-education Telehealth
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Ian Boggero, PhD
TMJ Disorder
Role of Ultrasonography in Assessment of Tempromanbular Joint Disorders
Evaluation of US efficiency in assessment of the tempromandibular joint disorders in comparison with MRI as the gold standard for technique validation and evaluation of efficiency of therapeutic intra articular injection under…
- Trial name
- NCT05320770
- Testing
- US guided TMJ intra articular injection
- Volunteers
- 50 people
- Sponsor
- Sohag University
Temporomandibular Joint Disorders
Effectiveness of Cervical Stabilization Exercises in Individuals With Temporomandibular Joint Disorder
It is planned to examine the effect of cervical stabilization exercises on Temporomandibular Joint (TMJ) symptoms in individuals with TMJ disorder.
- Trial name
- NCT06472141
- Testing
- Cervical stabilization exercises, Standard treatment (Education + home exercises)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bitlis Eren University
Myofascial Pain, TMD
The Effectiveness of Kinesiotaping and Inactivation of Trigger Points in Chronic Myofascial Pain of TMD
In patients with a long-lasting TMD syndrome, especially of a muscular nature, palpation examination can locate the trigger points of pain (TrP) in the chewing muscles, i.e., the nodules in the shape of bumps the size of rice or…
- Trial name
- KT/TrP/TMD (NCT03398486)
- Testing
- Kinesiotaping, inactivation of trigger points (TrP)
- Volunteers
- 60 people
- Sponsor
- Pomeranian Medical University Szczecin