Clinical trials: Manipulation, active
Chronic Pain
VCOM Pain Free Research Collaborative
Studies estimate that 30% of people worldwide experience chronic pain. The mechanisms causing this pain can vary: a neuropathic offender, such as nerve compression; a structural offender, such as long-term effects of soft tissue…
- Trial name
- MERCI (NCT06533345)
- Testing
- Behavior Change Coaching, Nutrition, Autonomic Recalibration
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Manual Therapy, Manipulation
Hip Manipulation in Basketball Players
Currently, it is difficult to find studies in the literature assessing the impact of manual therapy on preventing lower limb injuries in basketball players, which may later translate into improved strength and balance in…
- Conditions
- Manual Therapy, Manipulation, Muscles, Musculoskeletal System
- Trial name
- Manual Therapy (NCT06901089)
- Testing
- Manual therapy, Exercise
- Where
- Poland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases
This study will assess the safety, efficacy, and feasibility of ⍺/β CD3+ T-cell and CD19+ B-cell depletion in allogeneic stem cell transplantation in patients with acute lymphocytic leukemia (ALL), acute myeloid leukemia (AML)…
- Conditions
- Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Juvenile Myelomonocytic Leukemia, Myelodysplastic Syndromes
- Trial name
- NCT05800210
- Testing
- Miltenyi CliniMACS Prodigy ® system
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Florida
Spine Condition, Low Back Pain
Influence of Flexion Distraction Manipulation on Measures of Performance and Postural Control
This research study will evaluate human performance and postural balance changes during the course of care with flexion distraction manipulation in multiple chiropractic practices.
- Trial name
- NCT06965920
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Keiser University College of Chiropractic Medicine
Lumbar Disc Herniation
Brain Connectomic Mechanisms of Spinal Manipulative Therapy on LDH Analgesia Based on Multimodal MRI
Low back and leg pain caused by lumbar disc herniation (LDH) is common. Lever positioning manipulation (LPM) is a spinal manual therapy used to relieve this pain, but how it affects the brain is unclear.
- Trial name
- NCT07728149
- Testing
- Active Lever Positioning Manipulation
- Where
- China
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Piriformis Syndrome
Comparative Effects of Stecco-fascial Manipulation and Rolfing Structural Integration in Patients With Piriformis Syndrome
This study aims to compare the effectiveness of Stecco Fascial Manipulation and Rolfing Structural Integration in treating Piriformis syndrome, focusing on special outcomes like pain severity and functional outcomes.
- Trial name
- Piriformis (NCT07322185)
- Testing
- Experimental: GROUP A ( Stecco fascial Manipulation), Experimental: GROUP B (Rolfing Structural Integration)
- Where
- 3 sites in Pakistan
- Volunteers
- 42 people
- Sponsor
- Danyal Ahmad
Acute Respiratory Distress Syndrome, COVID-19
Trans Thoracic Manipulation of Ventilation/Perfusion: the V/Q System
The purpose of this pilot study is to measure the impact of non-invasive pneumatic manipulation of transthoracic pressure on oxygenation in patients with Acute Respiratory Distress Syndrome (ARDS) due to Coronavirus Disease 2019…
- Trial name
- NCT04369599
- Testing
- V/Q System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Emory University
MECHANICAL BACK PAIN, Sleep Quality
Investigation of the Effect of Thoracic Manipulation and Classical Massage on Pain, Flexibility and Sleep Quality
Investigation Of The Effects Of Thoracic Manipulation And Classical Massage On Pain Flexibility And Sleep Quality In Patients With Mechanical Back Pain
- Trial name
- NCT07518732
- Testing
- Classical Massage, Manual therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ayşe BAŞAYAN
Cervicogenic Headache, Whiplash Injuries
Manipulation and Dry Needling in Patients With Cervicogenic Headache and WAD II
The purpose of this research is to compare two different approaches for treating patients with cervicogenic headaches associated with type II whiplash associated disorder: non-thrust mobilization and exercise versus thrust…
- Trial name
- NCT06502951
- Testing
- Dry Needling,Thrust Manipulation, Exercise,Non-thrust Mobilization
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Alabama Physical Therapy & Acupuncture
Neonatal Disorder
Impact of Tactile Kinesthetic Stimulation and Soft Tissue Manipulation on Cortisol in Preterm
Effect of Soft tissue Therapy in managing Procedural Pain among neonates admitted to the neonatal intensive care unit. This study focuses on procedural pain management with the help of Soft tissue manipulation, which includes…
- Trial name
- NCT06845137
- Testing
- Tactile-Kinesthetic Stimulation (TKS) and Soft Tissue Manipulation (STM), Standard Therapy
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- faizan kashoo, PT
Parkinsons Disease, Sleep
Effects of Osteopathic Manipulative Treatment Protocol on Sleep Quality in Parkinson's Disease Subjects
Parkinsonism, mainly caused by Parkinsons disease (PD), includes symptoms like tremors, stiffness, slow movements, and balance problems.
- Trial name
- NCT06671600
- Testing
- Osteopathic Manipulative Treatment
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- New York Institute of Technology
Healthy
ImmunoBoost: The Lymphatic Osteopathic Manipulative Treatment Protocol Study
The goal of this clinical trial is to determine whether osteopathic manipulative treatment (OMT) enhances immune system readiness in healthy adults compared to exercise or sham light treatment.
- Trial name
- NCT06565065
- Testing
- Osteopathic Manipulative Treatment (OMT), Exercise Protocol
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Western University of Health Sciences
Epilepsy, Seizures
Pharmacological Modulation of Brain Oscillations in Memory Processing
The goal of this study is to learn about the effects of scopolamine (an anticholinergic drug) on areas of the brain involved in memory, and changes it may have on brain activity.
- Conditions
- Epilepsy, Seizures, Cognitive Impairment, Mild, Memory Disorders
- Trial name
- NCT05594017
- Testing
- Scopolamine (0.4mg)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Chronic Nonspecific Low-back Pain, CNSLBP
Effects of Virtual Reality Exergames Versus Spinal Manipulation in Chronic Nonspecific Low Back Pain
The goal of this clinical trial is to compare the acute effects of virtual reality exergames (VR-EXG) and spinal manipulation on pain, kinesiophobia, mood states, functional disability and lumbar range of motion in individuals…
- Trial name
- NCT07876960
- Testing
- Virtual Reality, Spinal manipulation
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Healthy
Application of Manual Therapy to Archers
The aim of this study is to: (i) characterize the effect of repeated archery shots on the EMG parameters of certain selected upper limb muscles; and (ii) evaluate how manipulation of the initial two-second tension phase, in…
- Trial name
- NCT06747104
- Testing
- Manual therapy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Obesity
Systemic Vibratory Therapy and Osteopathic Manipulative Treatment in Individuals With Obesity
Studies have demonstrated a strong relationship between physical inactivity and the presence of obesity and other cardiovascular risk factors such as hypertension, insulin resistance, diabetes, dyslipidemia, and metabolic…
- Trial name
- SVT and OMT (NCT06971159)
- Testing
- Systemic vibratory therapy, Osteopathic manipulative treatment
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Laboratorio de Vibraçoes Mecanicas e Praticas Integrativas
Tension-Type Headache
HVLAT, Electric DN, Exercise Vs. Mobilization, STM, Exercise, TENS for Tension Type Headaches
The purpose of this research is to compare two different approaches for treating patients with tension-type headaches: thrust Manipulation, electric dry Needling and exercise Vs.
- Trial name
- NCT04609709
- Testing
- Thrust Manipulation, Electric Dry Needling and Exercise, Non-thrust Mobilization, Soft-Tissue Mobilization, Exercise and TENS
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Alabama Physical Therapy & Acupuncture
Postpartum Lumbopelvic Pain, Postpartum Pelvic Girdle Pain
Osteopathy in Postpartum Lumbopelvic Pain
Postpartum lumbopelvic pain is a common condition after childbirth and may affect pain levels, physical function, daily activities, and quality of life.
- Conditions
- Postpartum Lumbopelvic Pain, Postpartum Pelvic Girdle Pain, Postpartum Low Back Pain
- Trial name
- NCT07631949
- Testing
- Core Stabilization Exercises, Patient Education, Osteopathic Manipulative Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Halic University
Head Injury Trauma
Osteopathic Manipulative Treatment RCT and Computational Modeling for Head Injuries in Mixed Martial Artists
The purpose is to test how osteopathic medicine (OMM) improves recovery after a hit to the head during Mixed Martials Arts (MMA).
- Trial name
- NCT06851234
- Testing
- osteopathic manipulative medicine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- New York Institute of Technology
Lateral Epicondylitis (Tennis Elbow)
Effectiveness of Extracorporeal Shockwave Therapy Based on Fascial Manipulation Theory for Lateral Epicondylitis
Goal: This clinical trial aims to find out if using fascial theory to guide shockwave therapy works better for treating "tennis elbow" (pain on the outer side of the elbow) compared to standard shockwave treatment.
- Trial name
- NCT07131423
- Testing
- Standard extracorporeal shock wave therapy, CC points shock wave therapy, Shock wave therapy for the CC points and the lateral epicondyle
- Where
- China
- Volunteers
- 123 people
- Sponsor
- ZHANG PENG