Clinical trials: Marginal Bone Loss, active
Dental Implant-Abutment Designs, Marginal Bone Loss in Different Abutment Designs
Peri-implant Tissues Changes for Different Abutment Shapes and Heights
The goal of this randomized clinical trial is to investigate the influence of supracrestal soft tissue on abutments of different heights (2-mm vs. 3-mm) and shapes (cylindrical abutment vs.
- Conditions
- Dental Implant-Abutment Designs, Marginal Bone Loss in Different Abutment Designs, Soft Tissue Management in Subcrestal Dental Implants
- Trial name
- NCT07509281
- Testing
- Bone-Level Implant Placement with Transmucosal Abutment and One Abutment-One Time Protocol
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Jaw, Edentulous, Partially
Evaluation of Marginal Bone Loss and Associated Factors Around Ziacom Dental Implants With Different Prosthetic Connection
Dental implants may suffer from bone loss around them, particularly at the upper portion where the prosthesis starts. The connection between both parts of the tooth restoration is key for avoiding micromovement during chewing…
- Trial name
- NCT05859113
- Testing
- Ziacom Galaxy dental implant with internal connical prosthetic connection, Ziacom Zinic dental implant with internal hexagonal prosthetic connection
- Where
- Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Tooth Loss in the Anterior Maxilla, Partial Edentulism of the Maxilla
A Follow-Up Study of Straight and Tapered Dental Implants in the Front Upper Jaw
This prospective study aims to evaluate 5-year clinical, radiographic, and patient-reported outcomes of implant-supported crowns and bridges placed on Neoss implants (ProActive Straight and Tapered) in the anterior maxilla…
- Trial name
- NCT07544706
- Testing
- Neoss Implant System (ProActive Straight and Tapered)
- Where
- Sweden
- Volunteers
- 51 people
- Sponsor
- Branemarkkliniken
Bone Loss
Prosthetic Modality and MBL
The present study will test the effect of different prosthetic modalities on conical and internal hex connection implants, assessing the radiographic MBL changes after one year.
- Trial name
- NCT07156110
- Testing
- Traditional prosthetic procedure, one abutment-one time
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Studio Odontoiatrico Associato Dr. P. Cicchese e L. Canullo
Soft Tissues According to the Abutment Torque, Microleakage Accordint to the Abutment Torque
Impact of Abutment Screw Torque on Marginal Bone Loss
The objective of this clinical trial is to evaluate the impact of different torque values applied during transmucosal abutment placement in dental implants on marginal bone loss and peri-implant parameters, including the…
- Conditions
- Soft Tissues According to the Abutment Torque, Microleakage Accordint to the Abutment Torque, PROMS According to the Abutment Torque, Marginal Bone Loss According to the Abutment Torque
- Trial name
- NCT07234552
- Testing
- Abutment torqued to 15 Ncm, Pilar torqued to 30 Ncm, 2 mm healing cap
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Tooth Loss, Edentulism
PMCF Study on the Effectiveness and Safety of BIODENTOSS® and DWC® Dental Implants and Superstructures
This prospective, single-center, interventional post-market clinical follow-up (PMCF) study aims to evaluate the early-term (24 months post-implantation) safety and efficacy of CE-marked BIODENTOSS® and DWC ® Dental Implants and…
- Trial name
- NCT07633665
- Testing
- BIODENTOSS Bone-Level Dental Implant and Superstructures, DWC Bone-Level Dental Implant and Superstructures
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Değirmenci Otomotiv ve Metal Endüstri A.Ş.
Postmenopausal Peri-implant Health, Postmenopausal Peri-mucositis
Evaluation of aMMP-8 and IL-1β Levels and Marginal Bone Loss Associated With Peri-Implant Mucositis and Peri-Implantitis in Postmenopausal Women
Peri-implant mucositis and peri-implantitis are among the major biological complications threatening the long-term success of dental implants.
- Conditions
- Postmenopausal Peri-implant Health, Postmenopausal Peri-mucositis, Postmenopausal Peri-implantitis
- Trial name
- NCT07785817
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medipol University
Tooth Loss / Rehabilitation, Dental Implant
Standard- and Micro-Dose rhBMP-2 for Implant Stability, Marginal Bone Loss, and Postoperative Sequelae: A Double-Blind Randomized Controlled Trial
This study will compare the effect of standard-dose and micro-dose recombinant human bone morphogenetic protein-2 (rhBMP-2) with a placebo control on dental implant stability in the posterior mandible.
- Conditions
- Tooth Loss / Rehabilitation, Dental Implant, Osseo-Integrated Implants
- Trial name
- SMBMP (NCT07696299)
- Testing
- Standard-dose rhBMP-2, Micro-dose rhBMP-2, Sterile Normal Saline
- Where
- Iraq
- Volunteers
- 60 people
- Sponsor
- University of Baghdad
Edentulism, Dental Implantation, Endosseous
Subcrestal vs Juxtacrestal PRAMA Implants With Variable Necks
The goal of this clinical trial is to understand how different implant neck designs and placement depths affect the surrounding bone and peri-implant tissue (the tissue around a dental implant) in adults who need implants in the…
- Conditions
- Edentulism, Dental Implantation, Endosseous, Marginal Bone Loss, Periimplant Bone Loss
- Trial name
- NCT07107464
- Testing
- Short Neck Implant - Crestal Placement, Standard Neck Implant - 1 mm Subcrestal Placement, Long Neck Implant - 2 mm Subcrestal Placement
- Where
- Cuba
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ARDEC Academy
Dental Implant, Implant Stability
Analysising the Marginal Bone Loss, Torque and Implant Stability Placed in Bone and Tissue Level Dental Implants
It is a prospective clinical study to compare two implants of the same brand of a similar design for implantation [either at the bone tissue level or at the soft tissue level], in order to evaluate the marginal bone loss of each…
- Trial name
- NCT07288606
- Testing
- Dental implant placement
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- University of Barcelona
Dental Implant, Wound Healing
Lactoferrin Nanohydrogel for Soft And Hard Tissue Healing and Implant Stability in Immediate Implant Placement
The goal of this randomized clinical trial is to evaluate whether local application of a 4% bovine lactoferrin nanohydrogel improves soft tissue healing, bone healing, and implant stability following immediate dental implant…
- Trial name
- LF (NCT07889674)
- Testing
- 4% bovine lactoferrin nanohydrogel
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Future University in Egypt
Guided Implant Placement, Delayed Implant
Qualitative and Quantitative Assessment of Marginal Bone Loss Following Flapless Guided Versus Conventional Implant Placement
Marginal bone preservation is an important determinant of long-term implant success. Conventional flap implant placement provides direct visualization of the surgical site but may disturb the periosteal blood supply and…
- Conditions
- Guided Implant Placement, Delayed Implant, CBCT Segmentation
- Trial name
- NCT07663045
- Testing
- Conventional Flap Implant Placement, Flapless guided implant
- Where
- United Arab Emirates
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Dental Implant Placement, Soft Tissue Management in Subcrestal Dental Implants
Implant Placement Depth and Peri-Implant Tissue Outcomes
The primary aim of this randomized clinical trial is to evaluate the influence of subcrestal implant placement depth (-2 mm vs -4 mm) on peri-implant marginal bone level changes, including marginal bone loss and bone remodeling.
- Conditions
- Dental Implant Placement, Soft Tissue Management in Subcrestal Dental Implants, Marginal Bone Loss
- Trial name
- NCT07535528
- Testing
- Subcrestal Implant Placement with Transmucosal Abutment and One Abutment-One Time Protocol
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Edentulism, Tooth Loss
Mandibular Biological Drilling at Different Speeds for Dental Implant Placement
This randomized controlled clinical trial aims to evaluate the effect of different biological drilling speeds (50, 150, and 300 rpm) during implant osteotomy preparation in the mandible on marginal bone level changes and implant…
- Trial name
- NCT07474454
- Testing
- biological drilling at 50 RPM, biological drilling at 150 RPM, biological drilling at 300 RPM
- Volunteers
- 39 people
- Sponsor
- Cairo University
Prosthodontics, Implants, Dental
Effect of PEEK and Titanium Framework Reinforcement on Marginal Bone Loss Around Implants Supporting a Fixed All-on-four Prosthesis in Completely Edentulous Mandibles
A fixed all-on-four prosthesis will be constructed for the lower arch for each patient and the marginal bone loss will be evaluated at baseline, 3,6,9 and 12 months.
- Conditions
- Prosthodontics, Implants, Dental, Prosthesis, Bone Loss, Alveolar
- Trial name
- NCT07475507
- Testing
- Titanium framework reinforced all on four prosthesis, PEEK framework reinforced all on four prosthesis
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Teeth Absent, Tooth-loss
Peri-implant Tissues on the Galimplant Anti-rotational Slim Abutment.
A dental implant is an alloplastic material surgically inserted in a residual bone ridge, mainly with a prosthetic foundation. Nowadays the most widely used implants and with a higher degree of scientific evidence are the…
- Conditions
- Teeth Absent, Tooth-loss, Tooth Extraction, Dental Implant
- Trial name
- NCT05118815
- Testing
- Slim abutment, Standard abutment
- Where
- Spain
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Dental Implants, Immediate Dental Implant Loading
Immediate Restoration of a New Implant With High Primary Stability
The main objective of this scientific study is to evaluate the short-term (1-year) survival and success rates of dental implants restored immediately compared to implants restored after a three-month healing period.
- Trial name
- CT (NCT07498556)
- Testing
- Control Group, Test group - Implant restoration with a temporary crown
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Universidade do Porto
Tooth Loss, Partial Edentulism in the Maxilla or in the Mandible
Evaluation of Autogenous Bone Graft on Immediate Dental Implant Osseointegration Using Piezosurgery
This clinical study aims to evaluate the clinical and radiographic outcomes of immediate dental implant placement in mandibular premolar sites.
- Trial name
- ABG-IDIP (NCT07705399)
- Testing
- Immediate implant with autogenous bone graft, Immediate implant without bone graft
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Vitamin D Deficiency, Implant Assesment
Effect of Vitamin D on the Clinical and Radiographic of Unsplinted Mandibular Implant Overdentures
This study investigates the effect of vitamin D on bone loss around mandibular implant overdentures. Bone levels around implants will be measured to understand how vitamin Daffect the health of implant-supported dentures.
- Conditions
- Vitamin D Deficiency, Implant Assesment, Radiography, Clinical and Radiographic Effect
- Trial name
- Vit D and bone (NCT07200011)
- Testing
- Observational: Serum Vitamin D Levels
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Peri-implantitis, Alveolar Bone Loss
Diagnostic Accuracy of Large Language Models for Peri-Implant Marginal Bone Loss on Panoramic Radiographs
Dental implants are a routine treatment for missing teeth, but the number of implants affected by peri-implantitis, a progressive inflammatory disease of the tissues around implants, is increasing.
- Conditions
- Peri-implantitis, Alveolar Bone Loss, Dental Implant
- Trial name
- NCT07907900
- Testing
- Multimodal large language model evaluation (ChatGPT, Gemini, Claude, DeepSeek, Grok)
- Where
- Turkey (Türkiye)
- Volunteers
- 784 people, healthy volunteers welcome
- Sponsor
- Ankara University