Clinical trials: Marijuana Abuse
HIV Infections
Integrated Treatment of Marijuana Abuse for HIV+ Youth
This is an exploratory study that will adapt and test a combined cognitive behavioral treatment and contingency management intervention for alcohol and/or marijuana abuse for use in HIV-infected adolescents.
- Trial name
- NCT00683488
- Testing
- Focus Group, First Intervention Trial, Intervention Trial 2
- Where
- 3 sites in United States
- Volunteers
- 46 people
- Sponsor
- University of North Carolina, Chapel Hill
Cannabis Use
Effect of Cannabidiol (CBD) on Vision and Driving
The use of cannabis with ∆9-tetrahydrocannabinol (THC) content has been shown to have negative effects on vision and driving. The use of other cannabinoids, such as cannabidiol (CBD), which is not attributed with a psychoactive…
- Trial name
- NCT06322303
- Testing
- CBD 15%, CBD 30%
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Addiction, Behavioral Addiction
Mobile Health for Problematic Behaviors and Substance Use
The aim of the study is to evaluate the effectiveness of long-term and short-term app-based self-guided psychological interventions to reduce craving and lapse risk in problematic behaviors (compulsive sex, pornography…
- Conditions
- Addiction, Behavioral Addiction, Nicotine Addiction, Nicotine Dependence
- Trial name
- NCT05434429
- Testing
- mobile application
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- PredictWatch
Marijuana Smoking
Effect of Quetiapine on Marijuana Withdrawal and Relapse
The objective of this study is to investigate the interaction between marijuana and quetiapine, with the goal of using this information to improve marijuana treatment outcome.
- Trial name
- NCT00743366
- Testing
- Marijuana, Quetiapine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Adolescent Cannabis Use Disorder
Biofeedback for Adolescent Cannabis Use Disorder
The aims of this study are: 1) to estimate the effect size of HRV biofeedback for stress in adolescents undergoing cognitive behavioral therapy (CBT) for cannabis use disorder (primary outcome: Perceived Stress Scale) and 2) to…
- Trial name
- NCT02059083
- Testing
- Heart rate variability biofeedback, CBT
- Sponsor
- Denver Health and Hospital Authority
Glioblastoma, Brain Tumor
ARISTOCRAT: Blinded Trial of Temozolomide +/- Cannabinoids
ARISTOCRAT is a phase II, multi-centre, double-blind, placebo-controlled, randomised trial to compare the cannabinoid Nabiximols with placebo in patients with recurrent MGMT methylated glioblastoma (GBM) treated with temozolomide…
- Conditions
- Glioblastoma, Brain Tumor, Cannabis, Brain Tumor, Recurrent
- Trial name
- ARISTOCRAT (NCT05629702)
- Testing
- Nabiximols, Temozolomide
- Where
- 17 sites in United Kingdom
- Volunteers
- 122 people
- Sponsor
- University of Birmingham
Cannabis, Marijuana Abuse
Dronabinol Interactions With Cognitive Enhancing Drug in Humans
Marijuana use is a major problem among veterans and non-veterans. A patient's use of marijuana while engaged in psychotherapy treatment may affect their memory and, therefore, limit their ability to benefit from treatment.
- Trial name
- NCT00842985
- Testing
- drug condition
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Yale University
Alcohol Use Disorder
Alcohol Use Disorder and Cannabidiol
This is a double-blind, placebo-controlled, parallel group study designed to assess the efficacy of full spectrum CBD and broad spectrum CBD, compared to a placebo control (PC), to reduce drinking in participants with alcohol use…
- Trial name
- NCT05613608
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Colorado, Denver
Prenatal Alcohol Exposure, Prenatal Tobacco Exposure
Choices4Health: Intervention to Prevent Substance-exposed Pregnancy
This is a 4-year randomized, controlled study to test the efficacy of the CHOICES4Health-T (C4H-T) delivered by a computerized tablet, CHOICES4Health-C (C4H-C), delivered by a counselor, and brief advice (BA), on reducing…
- Conditions
- Prenatal Alcohol Exposure, Prenatal Tobacco Exposure, Prenatal Marijuana Exposure
- Trial name
- C4H (NCT03633149)
- Testing
- Computer tablet-delivered C4H, Person-delivered C4H, Brief Advice
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Psychosis, Substance Use
Families With Substance Use and Psychosis: A Pilot Study
The purpose of this study is to develop and evaluate an intervention that adapts Community Reinforcement and Family Training (CRAFT) for families experiencing first episode psychosis and substance use delivered via telemedicine…
- Conditions
- Psychosis, Substance Use, Substance Use Disorders, Family
- Trial name
- NCT04284813
- Testing
- CRAFT-FT
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Insomnia, Depressive Disorder, Major
Cannabinoids as a Treatment for Insomnia in Major Depression
This single-site study is a pilot, three-armed, double-blinded, placebo-controlled randomized controlled trial (RCT) that will determine the feasibility of a definitive RCT investigating the use of cannabis oil as a treatment for…
- Conditions
- Insomnia, Depressive Disorder, Major, Sleep Disorder, Depression
- Trial name
- CANMDD (NCT05041647)
- Testing
- 25:1 CBD/THC, 5:1 CBD/THC
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Risk Reduction Behavior, Health Behavior
Alcohol, Marijuana, and Risky Sex: Group Interventions With Detained Adolescents
This research is studying behaviors that young people engage in that may place them at risk for contracting a sexually transmitted disease like HIV/AIDS, and what kind of educational program works best to reduce these risky…
- Conditions
- Risk Reduction Behavior, Health Behavior, Sexual Behavior, Adolescent Behavior
- Trial name
- MARS (NCT01170260)
- Testing
- INFORMATION-ONLY SEXUAL RISK REDUCTION (INFO-ONLY), SEXUAL PLUS ALCOHOL RISK REDUCTION (SRRI+ETOH), SEXUAL + ALCOHOL + MARIJUANA RISK REDUCTION
- Where
- United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Opioid Use Disorder
Evaluation of the Interactions of Cannabidiol (CBD) With Morphine
The purpose of this study is to analyze drug-drug interactions of CBD on co-administered Morphine as first step in understanding CBD-opioid interactions.
- Trial name
- NCT05143424
- Testing
- Morphine Sulfate
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Cannabis
The Pharmacokinetics and Pharmacodynamics of a Single Acute Dose of a Hemp-derived Oral Product With a 1:1 Ratio of CBD:CBD-A
The purpose of this study is to examine the pharmacokinetics and pharmacodynamics of a hemp-derived oral product containing cannabidiol (CBD) and cannabidiolic acid (CBD-A) at a 1:1 ratio.
- Trial name
- NCT05049733
- Testing
- CBD 1mg/Kg, CBD 2mg/Kg, CBD 4mg/Kg
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cannabis Use Disorder, Anxiety
Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use
The goal of this clinical trial is to learn if Therabot-CALM (Cannabis, Anxiety, Low Mood) has acceptability among users and could work to improve the symptoms of persons with cannabis use disorder and anxiety and/or depression.
- Conditions
- Cannabis Use Disorder, Anxiety, Depression, Anxiety, Depression - Major Depressive Disorder
- Trial name
- NCT06920238
- Testing
- Therabot-CALM
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Trustees of Dartmouth College
Cannabis Dependence, Psychostimulant Dependence
Evaluation of the Effects of Treatment of Psycho-stimulant and Cannabis-dependent Users in Israel
This study evaluates the effects of psychological and pharmacological treatment of regular users of cannabis and psychostimulants in a treatment center (Kfar Izun) in Israel.
- Trial name
- NCT01510015
- Testing
- Risperidone
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Eating Disorders, Cannabis Use
A Brief Cannabis Use Psychoeducation Intervention for Eating Disorder Patients
The goal of this clinical trial is to learn if providing eating disorder patients with education about the consequences of cannabis (marijuana) use on mental health, gastrointestinal symptoms, eating disorder symptoms, and eating…
- Trial name
- NCT07387965
- Testing
- Psychoeducation about risks of cannabis use
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Cannabis
Cerebellar Alterations in Individuals With a Cannabis Use Disorder
The purpose of this study is to investigate if individuals with a cannabis use disorder have an impaired cerebellar function by assessing possible alterations to their implicit adaptation during a visuomotor rotation task.
- Trial name
- NCT02816034
- Testing
- Visuo-motor rotation, Explicit strategy
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universitat Pompeu Fabra
Cannabis Use
Environment and Lung Cancer
Cannabis is the most consumed drug in the world and the French are the main consumers in Europe. The most recognized effects of cannabis on human health are of a neuro-psychic nature.
- Trial name
- ECP (NCT05119244)
- Testing
- blood and hair sampling
- Where
- 3 sites in France
- Volunteers
- 150 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
HIV Positive, Marijuana Smoking
Medical Marijuana Use in HIV+ Patients Prospective Cohort Study
The investigators are interested in understanding personal factors such as medical conditions and mental health, as well as social and economic factors, that influence marijuana (and other substance) use in HIV-positive patients.
- Trial name
- MMC-1 (NCT01536899)
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Wayne State University