Clinical trials: Marijuana Use
Child Development, Cannabis Use
Maternal Choline Supplementation and Cannabis Use During Pregnancy: Impact on Early Brain Development
The goal of this study is to determine if providing a nutritional supplement, phosphatidylcholine, to pregnant women who have used cannabis products during the current pregnancy improves the offspring\'s brain-related…
- Trial name
- NCT06379971
- Testing
- Choline
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Cannabis Use Disorder
Understanding Effects of Cannabis Use and Abstinence on Neural Glutamate Homeostasis
This study will be the first in vivo human multimodal neuroimaging study exploring the relationship between mGluR5 availability (PET), neural oscillations (EEG), and cognitive function in people with CUD.
- Trial name
- NCT05664763
- Testing
- [18F]FPEB with PET, Cannabis abstinence
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Yale University
Cannabis Use, Psychiatric Disorder
An Electronic Intervention to Reduce Cannabis Among Young Adults in Psychiatric Care
Cannabis use disorders are common among young adults in psychiatric treatment. Unfortunately, cannabis use can result in deleterious consequences for those in treatment, including developing more severe psychopathology and poorer…
- Trial name
- NCT04174963
- Testing
- eToke + TPsy
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Chronic Pain
Reactions of Older Adults Driving After Cannabis Exposure
Objective of the Protocol: The primary aim of the current protocol is to examine whether or not habitual use of medical marijuana affects psychomotor functioning operationalized as driving performance.
- Trial name
- ROADACE (NCT04629716)
- Testing
- Medical Cannabis
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Florida State University
Marijuana Usage, Alcohol Drinking
Neuroscience of Alcohol and Marijuana Impaired Driving
Alcohol is one of the most widely used intoxicants. The effects of driving while intoxicated are well documented, leading to the laws and regulations behind drunk driving.
- Trial name
- NCT03431987
- Testing
- One day with a dose of active THC cannabis paired with alcohol
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Pregnancy, Cannabis
Development of a Lifestyle Physical Activity Intervention to Reduce Risk for Perinatal Cannabis Use
This study will recruit 20 women who are high risk for prenatal cannabis use for a 12-week program of using the tracker and receiving a Lifestyle Physical Activity program.
- Trial name
- NCT05528380
- Testing
- LPA + Fitbit Intervention
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Marijuana Use
Effects of a Range of Naltrexone Doses in Combination With Smoked Marijuana
The purpose of this study is to determine if the subjective effects of marijuana will be decreased by low-doses (< 25 mg) of naltrexone and increased by high-doses (> 50 mg) of naltrexone.
- Trial name
- NCT00403117
- Testing
- Naltrexone 12 Mg+ Active Marijuana (3.27% THC), Naltrexone 25 Mg + Active Marijuana (3.27% THC), Naltrexone 50 Mg+ Active Marijuana (3.27% THC)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Opioid-use Disorder, Acceptability of Health Care
Patients' Attitudes Toward and Experiences With Buprenorphine Treatment
This study will disseminate five surveys collecting individual's attitudes and experiences during buprenorphine treatment for Opioid Use Disorder during the COVID-19 pandemic.
- Conditions
- Opioid-use Disorder, Acceptability of Health Care, Opioid-Related Disorders
- Trial name
- NCT05121428
- Where
- United States
- Volunteers
- 817 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Cannabis Use, Healthy
Reward and Drug Effects on Mood and Brain Response
The goal of the study is to better understand the neural mechanisms underlying the rewarding, reinforcing properties of delta-9-tetrahydrocannabinol (THC), the main psychoactive ingredient in cannabis, among healthy young adults.
- Trial name
- NCT04512365
- Testing
- THC
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Cannabis Use, Tobacco Use
Effect of Cannabis on E-Cigarette Use Behavior
The purpose of this study is to determine the impact of tetrahydrocannabinol (THC) administration on motivational, subjective, and physiological effects of electronic cigarettes.
- Conditions
- Cannabis Use, Tobacco Use, Electronic Cigarette Use
- Trial name
- NCT06609109
- Testing
- THC High Dose, THC Low Dose, THC 0mg
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Substance Use
Integration of (iSBIRT) for Teen Drug Use Into a Pediatric Network
The Goal of this project is to integrate a previously-tested internet-facilitated Screening, Brief Intervention, and Referral to Treatment (iSBIRT) system for adolescent substance use into a large network of primary care offices…
- Trial name
- NCT01454206
- Testing
- iSBIRT
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Cannabis Use Disorder
Cannabidiol Pharmacotherapy for Adults With Cannabis Use Disorder
Investigators aim to determine Epidiolex's promise as a pharmacotherapy for cannabis use disorder. Investigators hypothesize that Epidiolex, when added to medical management, will result in greater reductions in marijuana use…
- Trial name
- CBD (NCT03102918)
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Tobacco Use Disorder, Tobacco Use Cessation
Cannabis-Tobacco Co-Use Treatment Study
The purpose of the RECLAIM study is to evaluate the effectiveness of varenicline (sometimes known as Chantix) compared to placebo (an inactive substance) for the treatment of cigarettes and cannabis (marijuana).
- Conditions
- Tobacco Use Disorder, Tobacco Use Cessation, Cannabis Use, Cannabis Use Disorder
- Trial name
- RECLAIM (NCT06883162)
- Testing
- Varenicline, Counseling, Psychosocial modules
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Alcohol Use Disorder, Cannabis Use
Alcohol and Cannabis Concentrates Co-Administration
The goal of this study is to learn about the effects of combining alcohol with cannabis concentrate products which contain high levels of THC.
- Trial name
- NCT05999344
- Testing
- commercially available cannabis administered prior to commercially available alcohol, commercially available alcohol administered prior to commercially available cannabis
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Cannabis Use, Tobacco
Lung Health and Breath Biomarkers: Acute Effects of Inhaled Cannabis
This outpatient study examines how inhaled cannabis, combustible or vaporized, alters lung health and breath biomarkers compared to a tobacco cigarette.
- Conditions
- Cannabis Use, Tobacco, Biomarkers
- Trial name
- NCT07694466
- Testing
- Cannabis (THC), Tobacco Cigarette
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hannah Harris
Cannabis Use Disorder, Cannabis Dependence
N-acetylcysteine for the Treatment of Cannabis Dependence: Working Mechanisms
This study investigates the effects of repeated NAC administration on glutamate concentrations in the anterior cingulate cortex (ACC), on neurocognitive functioning, and on neuro-inflammatory parameters in adult…
- Trial name
- NCT03221231
- Testing
- N-acetylcysteine, Magnetic Resonance Imaging, Neurocognitive measures
- Where
- Belgium
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Cannabis Use, Cannabis
Joint Effort 2.0: a Mobile Application With University Students
The purpose of this study is to evaluate quantitatively and qualitatively a mobile application, Joint Effort, targeting safe cannabis use among consumers.
- Conditions
- Cannabis Use, Cannabis, Cannabis Dependence, Cannabis Smoking
- Trial name
- JOINTEFFORT (NCT05620433)
- Testing
- Joint Effort, Brief normative feedback and standard information
- Where
- Canada
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Pain;Sexual Intercourse;M
The Use of Mindful Compassion and Cannabis Suppositories for Anal Pain Among Men Who Have Sex With Men
Research aim: To determine how an online mindful-compassion intervention adjunct with cannabis suppositories might reduce anal pain during sexual intimacy among men who have sex with men.
- Trial name
- NCT06435650
- Testing
- Cannabis suppositories and mindful-compassion for anal pain, Mindful-compassion
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- London Metropolitan University
Psychotic Disorders, Cannabis Use Disorder
Investigating the Neural Correlates of Cognitive Function in Psychosis Patients and Non-Psychiatric Controls With Cannabis Use
Cognitive impairment is well established in people with psychosis and is associated with cannabis use. The current study will investigate the neurobiological basis of cognitive change associated with 28-days of cannabis…
- Conditions
- Psychotic Disorders, Cannabis Use Disorder, Cannabis Dependence, Cannabis Use
- Trial name
- NCT05445180
- Testing
- Contingency management
- Where
- Canada
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Cannabis Use, THC
Cannabis THC Potency, Metabolism, and Cognitive Impairment in Young Adults
The goal of this interventional study is to determine the impact of high potency THC product use on cognitive function of young adults aged 21-25.
- Conditions
- Cannabis Use, THC, Marijuana Use, Cognitive Impairment
- Trial name
- THC-YA (NCT06077292)
- Testing
- 15% THC Potency Reduction, 35% THC Potency Reduction
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco