Clinical trials: Marijuana Use, open to volunteers
Cannabis Use
SV2A in Older Adults
The aim of the study is to examine the effect of cannabis use on brain synaptic density among older adults using [11C]UCB-J PET imaging.
- Trial name
- NCT05465538
- Testing
- [11C]UCB-J PET
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Yale University
Cannabis Use Disorder
SCORE Emerging Adult Cannabis Use & Stress
The interface between cannabis use and stress is a particularly important focus for sex differences research in emerging adults.
- Trial name
- NCT05885542
- Testing
- Cannabidiol oral solution
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Medical University of South Carolina
Insomnia
Targeting Insomnia to Improve Outcomes in Adults With Problematic Cannabis Use
This study will compare the efficacy of telemedicine-delivered cognitive behavioral therapy for insomnia tailored for people using cannabis for sleep (CBTi-CB-TM) to telemedicine-delivered sleep hygiene education (SHE-TM) on…
- Trial name
- NCT05814822
- Testing
- Cognitive Behavioral Therapy for insomnia (CBTi-CB-TM), Sleep Hygiene Education (SHE-TM)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Michigan
Cannabis Use Disorder, Major Depressive Disorder (MDD)
Pregnenolone for Cannabis Use Disorder and Depression
This is UG3 phase of a multi-site, milestone-driven UG3/UH3 research program evaluating pregnenolone for individuals with co-occurring cannabis use disorder (CUD) and major depressive disorder (MDD).
- Trial name
- PREG-CUD-MDD (NCT07685964)
- Testing
- Pregnenolone
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Texas Southwestern Medical Center
Cannabis Use, Risk Perception
Testing Warning Labels for Retail Cannabis Products Using a Discrete Choice Experiment
This discrete choice experiment (DCE) study aims to address gaps in cannabis packaging regulatory research by testing how variations in cannabis packaging and health warning design impact reactions to packaging and intentions…
- Conditions
- Cannabis Use, Risk Perception, Decision Making
- Trial name
- NCT07701304
- Testing
- Discrete choice experiment (DCE) survey-experiment
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- University of Oklahoma
Cannabis Use, Substance Use Disorder (SUD)
Research Investigating Drug Effects-2 (RiDE-2)
The purpose of this study is to better understand how people's mood, behavior, and brains respond to different recreational drugs.
- Conditions
- Cannabis Use, Substance Use Disorder (SUD), Healthy
- Trial name
- RiDE-2 (NCT06758596)
- Testing
- THC
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Cannabis Use Disorder
Cannabidiol and Cannabis Concentrate Users
This study is a randomized, placebo-controlled, dose-ranging trial of plant-derived cannabidiol (CBD) among people who regularly use cannabis concentrates but are not trying to stop or cut down on their use.
- Trial name
- NCT06575751
- Testing
- Broad Spectrum Cannabidiol (bsCBD) 400 mg, Broad Spectrum Cannabidiol (bsCBD) 200 mg
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Colorado, Denver
Schizophrenia, Cannabis Use Disorder
Genetic Basis of the Risk and Consequences of Cannabis Exposure in Humans
Cannabis is widely used worldwide and is associated with negative outcomes including cannabis use disorder (CanUD), psychosis, and cognitive impairment amongst others.
- Trial name
- NCT06058702
- Testing
- Delta-9-THC Very Low Dose, Delta-9-THC Medium Dose
- Where
- United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Yale University
Methamphetamine Induced Psychosis, Cannabis Use
Psychiatric Symptom Characteristics in Methamphetamine-Induced Psychosis With and Without Lifetime Cannabis Use
This prospective cohort study aims to investigate factors associated with psychiatric symptom severity in participants diagnosed with methamphetamine-induced psychotic disorder (MP) with and without lifetime cannabis use (LCU).
- Trial name
- NCT07459270
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Elazığ Mental Health and Diseases Hospital
Adolescent Drinking, Cannabis Use
Effectiveness of Brief Intervention in Primary Care for Diverse Young People (Chat)
Brief motivational interviewing intervention to address alcohol use among diverse teens 12-17.
- Trial name
- NCT06699251
- Testing
- Chat, Enhanced Usual Care
- Where
- 3 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- RAND
Medical Cannabis
Medical Marijuana and Open Road Driving Task
Medical marijuana use among adults 50 and older has more than doubled in the past decade with exponential increases projected in this demographic by 2050, and prescription opioids are one of the most common treatments for pain…
- Trial name
- ROADACE (NCT06995937)
- Where
- 2 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Florida State University
Caregiver Burden, Cannabis Use
Skills for Talking About Cannabis for Families of Young Adults With Psychosis
The objectives of this research is to (1) create a family intervention and provider manual to train family members of young people with psychosis (YP-P) who are heavy cannabis users new communication skills to motivate change in…
- Conditions
- Caregiver Burden, Cannabis Use, Expressed Emotion, Communications Skills
- Trial name
- STAC (NCT06961877)
- Testing
- Cannabis Conversation Skills for Families (CCSF)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Washington
Cannabis Use Disorder, Cannabis Use Disorders
Effect of Semaglutide on Cannabis Use in Adults With Cannabis Use Disorder
The HASHTAG Study is investigating whether the medicine semaglutide can help adults with cannabis use disorder (CUD) reduce their cannabis use. Participants will be randomly assigned to receive either semaglutide or a placebo.
- Conditions
- Cannabis Use Disorder, Cannabis Use Disorders, Cannabis Abuse, Cannabis Dependence
- Trial name
- HASHTAG (NCT07523633)
- Testing
- semaglutide
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Anders Fink-Jensen, MD, DMSci
Insomnia, Alcohol Use
Brief Interventions to Reduce Comorbid Alcohol and Cannabis Misuse and Sleep Impairment in Young Adults (Rest-Up RCT)
This study is designed to evaluate an integrated intervention to reduce alcohol and marijuana use and consequences and improve sleep among young adults with comorbid heavy episodic drinking, marijuana use, and sleep impairment.
- Conditions
- Insomnia, Alcohol Use, Marijuana Use
- Trial name
- NCT06736444
- Testing
- Brief Behavioral Therapy for Insomnia (BBTI), Brief Alcohol Screening and Intervention for College Students (BASICS), Attention Control
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- University of Washington
Alcohol Misuse, Cannabis Misuse
MiREA-AC for Reducing Problematic Alcohol and Marijuana Use in College Students
The goal of this STTR Phase I funded study is to address the urgent need for an effective primary prevention approach to the problem of heavy episodic drinking and cannabis misuse among mandated college students.
- Trial name
- NCT07339150
- Testing
- Motivational Intervention Reduction through Ecological Application (MiREA-A). MiREA-AC-- the expanded MiREA-A,
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- mHealth Systems Inc.
Alcohol Drinking, Cannabis Use
Developing and Testing an Online Intervention for Alcohol and Cannabis Misuse and Healthy Relationship Skills Among Young Adult Couples
The goal of this clinical trial is to develop and test a brief online intervention to reduce alcohol and cannabis misuse and improve healthy relationship skills among young adult couples.
- Conditions
- Alcohol Drinking, Cannabis Use, Couples
- Trial name
- NCT06422299
- Testing
- Online, couples-based intervention
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Washington