Clinical trials: Mask
Oropharengeal Leak Pressure
Comparison of Oropharyngeal Leak Pressures of SaCo Video Laryngeal Mask Airway (LMA) and ProSeal LMA in Adult Elective Surgery
To compare of oropharyngeal leak pressures of SaCo video laryngeal mask airway (LMA) and ProSeal LMA in adult elective surgery
- Trial name
- NCT07688590
- Testing
- ProSeal LMA Group (Group-P), SaCo Video LMA Group (Group-V)
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Bronchial Asthma
N95 Masks for Lung Health While Golfing During Wildfire Season
Lung health is negatively affected during wildfire season by increased smoke pollution. Wearing N95 masks protects lung health in the short-term.
- Trial name
- NCT07620691
- Testing
- N95 mask
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Dry Eye Disease
Evaluation of Anti-Inflammatory Treatment in Dry Eye Patients
The purpose of this study was to determine if difluprednate ophthalmic emulsion is effective in reducing the ocular symptoms of dry eye disease, as measured by a global Visual Analog Scale (VAS) discomfort score.
- Trial name
- NCT01276223
- Testing
- Difluprednate 0.05% ophthalmic emulsion, Difluprednate vehicle
- Where
- United States
- Volunteers
- 722 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Dry Eye
A Study to Evaluate the Safety and Effectiveness Assessments of Restylane-Defyne for Punctual Occlusion
A study which participants with mild to moderate dry eye disease will have a punctum of one eye injected with 0.1ml Restylane Defyne and the other eye injected with 0.2ml Restylane Defyne.
- Trial name
- NCT04022382
- Testing
- Restylane Defyne
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- John C Meyer, MD
Forehead Rhytides, Forehead Wrinkles
Botulinum Toxin Type A Injection After Topical Anesthesia Versus Petrolatum Ointment
The purpose of this study is to determine whether there is a difference in clinical effect, duration of effect, level of discomfort and patient satisfaction in patients receiving topical anesthesia on one side of the forehead and…
- Trial name
- NCT03799484
- Testing
- Botulinum toxin type A, 2.5% lidocaine/2.5% prilocaine, petrolatum ointment
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Pseudophakia, Cataract Surgery
Randomized, Masked Comparison of Bromfenac and Besifloxacin BID With Either Prednisolone BID or Loteprednol 0.5% BID for Prevention of Retinal Thickening and CME Following Phacoemulsification
The purpose of this study is to determine if Lotemax eye drops are at least as effective as Pred Forte eye drops, which are the standard of care after cataract surgery.
- Trial name
- NCT01193504
- Testing
- Pred Forte, Lotemax
- Where
- 3 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Chronic Allergic Conjunctivitis
OTX-14-007: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Chronic Allergic Conjunctivitis
The objective of the study was to evaluate the efficacy and safety of OTX-DP (dexamethasone insert) 0.4 mg for intracanalicular use when placed in the canaliculus of the eyelid for the treatment of the signs and symptoms of…
- Trial name
- NCT02445326
- Testing
- Dexamethasone
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Ocular Therapeutix, Inc.
Safety Study
A Safety Study of IVMED-85 Ophthalmic Solution in Healthy Adults
The purpose of this trial is to determine the safety of IVMED-85 eye drops in healthy adult subjects. Participants will be assigned to either the active or vehicle eyedrop group.
- Trial name
- NCT07370584
- Testing
- IVMED-85 ophthalmic solution, Vehicle Ophthalmic Solution
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- iVeena Delivery Systems, Inc.
Myopia
Myopia Progression Trial With Novel Myopia Control Design Spectacle Lenses
This is a mono-center, randomized, double-masked, cross-over study to evaluate rate of myopia progression with novel designed myopia control lens (test) compared to SVL (control).
- Trial name
- NCT04048148
- Testing
- Novel designed myopia control spectacle lenses
- Where
- Vietnam
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Brien Holden Vision Institute
Labor, First Stage
Role of Hyoscine Bromide in Latent and Active Labor
The purpose of this study is to determine whether hyoscine bromide decreases the duration of the active phase of labor.
- Trial name
- NCT02103166
- Testing
- Hyoscine bromide, Physiological serum
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Presbyopia
Safety and Efficacy Study of BRIMOCHOL™ PF and Carbachol PF in Subjects With Emmetropic Phakic and Pseudophakic Presbyopia
Safety and Efficacy Study of BRIMOCHOL™ PF and Carbachol PF in Subjects With Emmetropic Phakic and Pseudophakic Presbyopia
- Trial name
- NCT05135286
- Testing
- BRIMOCHOL™ PF, Carbachol PF, Vehicle
- Where
- 42 sites in United States
- Volunteers
- 629 people, healthy volunteers welcome
- Sponsor
- Visus Therapeutics
Obstructive Sleep Apnea
PAP Systems External Clinical Studies (ECS)
This is a pre-market study for ongoing product development aiming to explore the usability and performance of the study PAP systems.
- Trial name
- NCT06562205
- Testing
- PAP System A (with Amalfi) then PAP System B (with CLA11), PAP System B (with CLA11) then PAP System A (with Amalfi)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ResMed
Cough, Laryngospasm
Benefits of Exchanging a Double Lumen Tube to a Proseal Laryngeal Mask or a Single Lumen Tube After a Thoracic Surgery
The purpose of this study is to determine whether exchange of the double lumen tube before emergence with a laryngeal mask airway (Proseal) or a tracheal tube will reduce cough at emergence.
- Conditions
- Cough, Laryngospasm, Apnea, Desaturation
- Trial name
- NCT00925613
- Testing
- LMA Proseal, Tracheal tube
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Airway Response
Optimal Dose of Alfentanil for Removal of Supreme Laryngeal Mask Airway During Emergence From Desflurane Anaesthesia
This study aims to determine the optimal dose of alfentanil in suppressing the airway reflexes during supreme LMA removal in anaesthetized adult.
- Trial name
- NCT01371968
- Testing
- alfentanil
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Laryngeal Mask Airway
Three Inflation Methods of the Ambú Auraonce™ and Its Adverse Effects
Laryngeal mask airway device (LMA) is a common device used in the daily practice for airway management. Consecutive generations have permitted an expansion of its use, probably because of a rapid increase of ambulatory surgical…
- Trial name
- NCT04769791
- Testing
- intracuff pressure measurement
- Where
- Spain
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Mydriasis, Dilation
Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis (MIRA-3)
The objectives of this study are: To evaluate the efficacy of Nyxol to expedite the reversal of pharmacologically-induced mydriasis across multiple mydriatic agents with an emphasis on phenylephrine To evaluate the efficacy of…
- Trial name
- MIRA-3 (NCT05134974)
- Testing
- Phentolamine Ophthalmic Solution 0.75%, Phentolamine Ophthalmic Solution Vehicle
- Where
- 15 sites in United States
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- Opus Genetics, Inc
Normal Volunteers
Formulation Comparison in Normal Volunteers
This is a double-masked, single-center, crossover study in which normal volunteers will be randomized to receive one of two formulations of 0.5% AR-12286 Ophthalmic Solution for 8 days.
- Trial name
- NCT01250197
- Testing
- AR-12286
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Aerie Pharmaceuticals
Anxiety, Child, Only
The Effect of Sound-Insulated Music Playing and Fıgured Mask Nebulızer Application on the Processing Anxiety of Children
The goal of this is a randomized controlled intervention study. The study was carried out to determine the effect of nebulization treatment applied to 3-6-year-old children with a soundproof, music player and figured mask…
- Trial name
- NCT05881941
- Testing
- using a soundproof nebulizer with a music and a funny mask added, using a silent nebulizer with no extra attachments, using a routinely employed nebulizer
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Eda SORKUN
Obstructive Sleep Apnea of Newborn
Nasal and Oronasal Mask in Severe OSA Patients With Nasal Free Airflow of Obstruction
The obstructive sleep apnea (OSA) affects between 10% to 25% of the adults. Continuous positive airway pressure (CPAP) is the first choice of treatment in severe OSA.
- Trial name
- NCT02274194
- Testing
- Nasal CPAP, Oronasal CPAP
- Where
- 2 sites in Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Covid19
Clinical Efficiency of Surgical Masks and Filtering Face-piece 2 Masks
Recent results demonstrated an increased risk of COVID-19 infection among healthcare workers (HCW), particularly when access to personal protective equipment (PPE) was inadequate. (ref).
- Trial name
- NCT04823351
- Testing
- Surgical Mask
- Where
- Switzerland
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Zurich