Clinical trials: Mask
Sleep Disorder; Breathing-Related
A Study to Determine Preferences Towards Interface Products
Enrolled Naïve participants will be randomized to one of two arms, the investigational or control arm. Once randomized the institutions will fit the participant with the procedures outlined in the protocol.
- Trial name
- NCT03948152
- Testing
- Standard of Care, Mask Advice Tool
- Where
- 5 sites in United States
- Volunteers
- 310 people
- Sponsor
- Philips Respironics
Neovascular Age-related Macular Degeneration
Efficacy and Safety of the Aflibercept FYB203 Biosimilar in Comparison to Eylea® in Patients With Neovascular Age-Related Macular Degeneration
This is a randomized, double-masked, multicenter study to evaluate the efficacy and safety of FYB203 compared to Eylea® in patients with neovascular age related macular degeneration.
- Trial name
- MAGELLAN-AMD (NCT04522167)
- Testing
- FYB203 (Proposed aflibercept biosimilar), Eylea® (Aflibercept)
- Where
- 66 sites in Bulgaria, Czechia and 7 more
- Volunteers
- 434 people
- Sponsor
- Bioeq GmbH
Exudative Age-Related Macular Degeneration
LHA510 Proof-of-Concept Study as a Maintenance Therapy for Patients With Wet Age-Related Macular Degeneration
The purpose of this study is to evaluate the efficacy of 84 successive days of topically administered LHA510 compared to vehicle in reducing the number of patients requiring intravitreal (IVT) anti-vascular endothelial growth…
- Trial name
- NCT02355028
- Testing
- LHA510 ophthalmic suspension, LHA510 vehicle, Ranibizumab ophthalmic solution
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Alcon, a Novartis Company
Focus is on Healthy Subjects
Reusable, Transparent, and Reconfigurable N95-equivalent Respirator Masks: Design, Fabrication, and Trials for Enhanced Adoption
The goal of this observational usability study was to evaluate the comfort, breathability, fit, communication, and user acceptance of the SEEUS95 transparent reusable respirator in healthy adult volunteers.
- Trial name
- NCT07711145
- Testing
- Reusable, Transparent, and Reconfigurable N95-Equivalent Respirator Masks: Design, Fabrication, and Clinical Trials for Enhanced Adoption
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- SEEUS95 Inc
Airway Complication of Anaesthesia
The Clinical Efficacy of Recently Developed Supraglottic Airway Device, I-gel™, in Neonates and Infants: Comparison With Classic-laryngeal Mask Airway (c-LMA)
Although the safety and efficacy of the Classic-laryngeal mask airway (c-LMA) in children has been shown in several large observational studies, findings suggest that the smaller-sized c-LMAs, in particular sizes 1 and 1½, are…
- Trial name
- NCT01437137
- Testing
- classic-laryngeal mask airway (c-LMA), i-gel™
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Yonsei University
Postoperative Sore Throat
Effect of Chewing Gum and Mouthwash Before Operation on Sore Throat After General Anesthesia With a Laryngeal Mask
Postoperative sore throat (POST) is an important problem after general anaesthesia. We assessed whether chewing gum preoperatively or mouthwash can reduce the incidence of POST after general anaesthesia administered via a…
- Trial name
- NCT04644900
- Testing
- chewed mint gum, Mouthwash
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Fudan University
Eyelash Hypotrichosis
Safety and Efficacy Study of Bimatoprost in Japanese Patients With Eyelash Hypotrichosis
This study will evaluate the safety and efficacy of bimatoprost solution 0.03% compared with vehicle in Japanese adults with hypotrichosis of the eyelashes.
- Trial name
- NCT01391273
- Testing
- bimatoprost solution 0.03%, bimatoprost vehicle solution
- Where
- Japan
- Volunteers
- 173 people
- Sponsor
- Allergan
Adhesive Capsulitis, Post-operative Pain
Shoulder Adhesive Capsulitis and Ambulatory Continuous Interscalene Nerve Blocks
Research study to determine if putting local anesthetic through a tiny tube next to the nerves that go to the shoulder will improve shoulder range-of-motion following the shoulder procedure performed on the frozen shoulder.
- Trial name
- NCT00875862
- Testing
- Interscalene catheter with Ropivicaine or normal saline
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, San Diego
Respiratory Insufficiency
Helm CPAP Versus Mask CPAP After Major Abdominal Surgery
Postoperative pulmonal complications (Abbreviation - PPC) after major abdominal surgery remains a significant clinical problem delaying rehabilitation after surgery.
- Trial name
- NCT02173327
- Testing
- Continuously helm CPAP, Intermittent Mask CPAP
- Where
- Denmark
- Volunteers
- 102 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Open Angle Glaucoma, Ocular Hypertension
A Study of Open Angle Glaucoma or Ocular Hypertension in Patients Within Scandinavia
PhXA41 is not inferior to timolol in reducing intra-ocular pressure
- Trial name
- NCT00751062
- Testing
- timolol, PhXA41
- Where
- 13 sites in Denmark, Finland and 2 more
- Volunteers
- 267 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Mastectomy, Upper Limb Amputation Below Elbow
Cryoanalgesia to Prevent Acute and Chronic Pain Following Surgery: A Randomized, Double-Masked, Sham-Controlled Study
The ultimate objective of the proposed line of research is to determine if cryoanalgesia is an effective adjunctive treatment for pain in the period immediately following various painful surgical procedures; and, if this…
- Conditions
- Mastectomy, Upper Limb Amputation Below Elbow, Upper Limb Amputation Above Elbow, Lower Limb Amputation Below Knee
- Trial name
- NCT03578237
- Testing
- Cryoneurolysis (active)
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of California, San Diego
Retinopathy, Diabetic
A Phase 2 Clinical Study to Investigate Effects of Darapladib in Subjects With Diabetic Macular Edema
The purpose of this study is to characterize the systemic and ocular safety and tolerability, pharmacokinetics, exploratory efficacy and pharmacodynamics of 3 months of repeat administration of oral darapladib in diabetic macular…
- Trial name
- NCT01506895
- Testing
- darapladib
- Where
- 16 sites in Australia, Denmark and 3 more
- Volunteers
- 54 people
- Sponsor
- GlaxoSmithKline
Myopia, Progressive
Efficacy of IVMED-85 on Pediatric Myopia
The goal of this clinical trial is to evaluate the safety and preliminary efficacy of a 1-year course of IVMED-85 eye drops for the treatment of pediatric myopia by assessing its safety effects on visual acuity and its effect on…
- Trial name
- NCT05761795
- Testing
- IVMED 85
- Volunteers
- 216 people
- Sponsor
- iVeena Delivery Systems, Inc.
Gastric Insufflation
Gastric Insufflation and Laryngeal Mask Airway
Comparison of the incidence of gastric insufflation between two kinds of laryngeal masks airways: LMA SupremeTM vs Ambu AuraOnceTM
- Trial name
- NCT02097771
- Testing
- LMA SupremeTM, AuraOnceTM
- Where
- France
- Sponsor
- Lionel Bouvet
Cardiac Arrest (CA), In-Hospital Cardiac Arrest
The Ventilation During In-hospital Cardiac Arrest Study
The goal of this prospective observational study is to learn how ventilation quality parameters during cardiopulmonary resuscitation (CPR) are associated with short-term survival following in-hospital cardiac arrest of adult…
- Conditions
- Cardiac Arrest (CA), In-Hospital Cardiac Arrest, Heart Arrest
- Trial name
- VENT-IHCA (NCT06809309)
- Testing
- Positive pressure ventilation during cardiopulmonary resuscitation
- Where
- 11 sites in Denmark, Norway
- Volunteers
- 900 people
- Sponsor
- University of Aarhus
Obstructive Sleep Apnea (OSA)
Foam Mask - Assessment of Bioburden in a New Mask Seal Material
Obstructive sleep apnoea (OSA) is characterised by a partial or complete collapse of the upper airway during sleep. The treatment of choice for OSA is Continuous Positive Airway Pressure (CPAP).
- Trial name
- NCT00773721
- Testing
- CPAP mask
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- ResMed
Laryngeal Mask Airway
Three Inflation Methods of Ambú Auragain™ and Its Adverse Effects
Laryngeal mask is a common supraglottic device (SGD) used in the daily practice for airway management. Consecutive generations have permitted an expansion of its use.
- Trial name
- NCT04795544
- Testing
- Intracuff pressure measurement
- Where
- Spain
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Macular Edema
A Study of MK0140 in Diabetic Patients With Macular Edema (0140-001)
This study will evaluate the treatment effect of three doses of the I-vation TA implant (MK0140) in diabetic patients with clinically significant macular edema.
- Trial name
- NCT00692614
- Testing
- triamcinolone acetonide
- Volunteers
- 2 people
- Sponsor
- Merck Sharp & Dohme LLC
the Efficacy and Performance of the Pediatric I-gel Mask
Application of I-gel Laryngeal Mask Airway in Pediatric Patients
Background The laryngeal mask airway (LMA) is a supraglottic airway device ,which is commonly used to manage children's airways, because it is typically easy to use and can avoid problems specific to tracheal intubation.
- Trial name
- NCT03748589
- Testing
- laryngeal mask airway
- Where
- China
- Volunteers
- 413 people
- Sponsor
- Xian Children's Hospital
General Anesthesia
Appropriate Laryngeal Mask Airway Size in Patients With Overweight: A Comparison of the Actual Body Weight and Ideal Body Weight
The classic laryngeal mask airway is one of the keystones of modern anaesthetic practice. It achieves a reliable airway with a low incidence of major complications and pharynges-laryngeal morbidity.
- Trial name
- NCT01843270
- Testing
- actual body weight based size, ideal body weight based size
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
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