Clinical trials: Masses
Clear Cell Renal Cell Carcinoma, Suspected Recurrent Renal Clear Cell Carcinoma
Evaluation of 89Zr-TLX250 PET/CT in Chinese Patients With Indeterminate Renal Masses or Suspected Recurrent Renal Clear Cell Carcinoma
The study is designed to evaluate the safety, tolerability, radiation dosimetry and pharmacokinetics 89Zr-TLX250 (also known as 89Zr-DFO-girentuximab) Positron Emission Tomography/Computed Tomography (PET/CT) in adult Chinese…
- Conditions
- Clear Cell Renal Cell Carcinoma, Suspected Recurrent Renal Clear Cell Carcinoma, Recurrent Renal Cell Cancer
- Trial name
- ZIRDOSE-CP (NCT05861778)
- Testing
- 89Zr-Girentuximab
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Telix Pharmaceuticals (Innovations) Pty Limited
Breast Cancer, Breast Abnormalities
Evaluate Breast Masses Using a New Method of Ultrasound Contrast to Detect Abnormal Blood Flow in Breasts
The purpose of this study is to determine if breast imaging with ultrasound can be improved by using 1) a ultrasound attachment with two transducers and 2) a contrast agent.
- Trial name
- NCT00722683
- Testing
- Ultrasound Imaging with Contrast
- Where
- United States
- Sponsor
- University of Michigan
Mammography, Breast Cancer
Searching for Masses and Calcifications at the Same Time in Breast Cancer Screening
Brief Summary A task like breast cancer screening (mammography) can be described as a "hybrid search" task. In basic visual search tasks, observers search for a target among distractors that are not the target.
- Conditions
- Mammography, Breast Cancer, Radiology
- Trial name
- NCT05975736
- Testing
- Search only for masses, Search only for calcifications, Search for both together
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Clear Cell Renal Cell Carcinoma
68Ga-NYM096 PET/ CT for the Detection of Clear Cell Renal Cell Carcinoma in Presurgical Patients With Renal Masses
This is a prospective, single-center, single-arm, diagnostic phase 2 study in patients who have renal masses scheduled for surgical resection.
- Trial name
- NCT07101900
- Testing
- 68Ga-NYM096 PET/CT
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Mediastinal ( Chest) Masses, Gastrointestinal Subepithelial Tumors
Role of Endoscopic Ultrasound Elastography in Diagnosis of Gastrointestinal Subepithelial and Mediastinal Lesions
The aim of this study is to evaluate the role of endoscopic ultrasound (EUS) in the diagnosis of mediastinal and gastrointestinal subepithelial lesions.
- Trial name
- NCT07419191
- Where
- Egypt
- Volunteers
- 35 people
- Sponsor
- Assiut University
Pancreatic Masses
RCT Comparing Accuracy Among Franseen, Forward-bevel Westcott, and Fork-tip EUS-FNB Needle in Diagnosis of Solid Pancreatic Lesions
Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA) is a well-established technique for pancreatic tissue acquisition, offering a high diagnostic accuracy ranging from 78% to 95%, along with a favorable safety profile.
- Trial name
- NCT07032974
- Testing
- Franseen, Forward-bevel, Fork-tip
- Where
- Thailand
- Volunteers
- 108 people
- Sponsor
- Mahidol University
Pancreatic Neoplasm
Comparing Biopsy Needles for Endoscopic Ultrasound Guided Samples for Pancreatic Masses
This is a randomized prospective clinical study comparing a fine needle biopsy device and an aspiration needle.
- Trial name
- Expect (NCT02911974)
- Testing
- Acquire EUS Biopsy Device, Expect EUS Aspiration Needle
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- AdventHealth
Ovary Cancer
The Efficacy and Safety of FRD001 in Ultrasound Contrast Imaging for Malignant Ovarian Masses in Women
This is a Prospective, Self-Controlled, Open-Label, Multicenter Clinical Trial. The purpose of this study is to demonstrate the efficacy and safety of FRD001 injection in ultrasound contrast imaging for the differentiation…
- Trial name
- NCT06556342
- Testing
- FRD001
- Where
- China
- Volunteers
- 198 people
- Sponsor
- Tongji Hospital
Kidney Cancer
Investigation of Differential Biology of Benign and Malignant Renal Masses Using Advanced Magnetic Resonance Imaging Techniques
The aim of this study is to develop techniques for non-invasive imaging of biology in participants with benign or malignant renal masses based on the novel scanning MRI techniques, including recently invented Hyperpolarised MRI…
- Trial name
- IBM-Renal (NCT06016075)
- Testing
- Hyperpolarised MRI, Sodium MRI, Deuterium metabolic imaging (DMI) MRI
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Cambridge
Postoperative Pain
Transumbilical Versus Lateral Transabdominal Removal of Benign Adnexal Masses Via Laparoscopy
In cases of benign adnexal mass laparoscopic surgery, women were randomized to two groups: transumbilical vs. transabdominal removal.
- Trial name
- NCT02704663
- Testing
- Transumbilical removal of specimen via laparoscopy, Lateral transabdominal removal of specimen via laparoscopy
- Where
- Finland
- Volunteers
- 42 people
- Sponsor
- Helsinki University Central Hospital
Kidney Cancer
Protocol Active Surveillance Small Renal Masses (SRMs)
Prospective study of active surveillance, non-randomized, multicentric, in asymptomatic patients over the age of 50 years, not affected by other tumors, with occasional diagnosis of single monolateral solid renal mass equal to or…
- Trial name
- NCT03804320
- Testing
- Active Surveillance
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- IRCCS San Raffaele
Ovarian Carcinoma, Ovarian Cancer
Study Into a New Diagnostic Tool (Simple Ultrasound-based Rules) in Patients With Adnexal Masses
This study is performed to compare the diagnostic performance and cost-effectiveness of different diagnostic methods for differentiating benign from malignant adnexal (ovary or Fallopian tube) masses: the Risk of Malignancy Index…
- Conditions
- Ovarian Carcinoma, Ovarian Cancer, Ovarian Mass, Ovarian Cyst
- Trial name
- SUBSONiC (NCT02218502)
- Testing
- Ultrasound by general gynaecologist, Ultrasound by an expert ultrasonographist, DW-MRI
- Where
- 5 sites in Netherlands
- Volunteers
- 50 people
- Sponsor
- Maastricht University Medical Center
Ovarian Cancer
Ultrasound RF Data for Discriminating Between Benign and Malignant Ovarian Masses
Ultrasound imaging provides useful information for the characterization of ovarian masses as benign or malignant. The most accurate mathematical model to categorize ovarian masses is the IOTA ADNEX model.This model estimates the…
- Trial name
- RFDATA (NCT06473766)
- Testing
- RF data extraction
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Osteosarcoma
Single High-dose Brachytherapy for Giant Osteosarcoma Masses
This study is a prospective, single-arm, phase II, single-center study. Patients with locally unresectable giant osteosarcoma masses who meet the criteria are enrolled in the experimental group, and all patients receive a single…
- Trial name
- NCT06524778
- Testing
- brachytherapy
- Volunteers
- 16 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Superficial Soft Tissue Masses
Role of MRI and US in Superficial Soft Tissue Masses
The goal of this observational study to evaluate the accuracy of Magnetic Resonance Imaging and Ultrasonography in characterization of superficial soft tissue masses.
- Trial name
- MRI/US in SSTM (NCT07294248)
- Testing
- Diagnostic imaging (US and MRI).
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Small Renal Mass, Kidney Tumor
GRADE-SRM: Genomic Risk Assessment and Decisional Evaluation for Small Renal Masses
Purpose: The purpose of this study is to evaluate the role of renal mass biopsy on decision-making for patients presenting with clinical T1 kidney tumors.
- Trial name
- GRADE-SRM (NCT03819569)
- Testing
- Small Renal Mass Biopsy, No Small Renal Mass Biopsy
- Where
- United States
- Volunteers
- 265 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Adrenal Mass
Gallium-68 Labeled Pentixafor PET/CT in Adrenal Masses
The CXC chemokine receptor type 4 (CXCR4), which is a G protein-coupled receptor expressed on the surface of the cell membrane, contributes to the development and progression of malignancies and functional endocrine disorders.
- Trial name
- NCT04859959
- Testing
- Gallium-68 Pentixafor PET/CT
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Breast Carcinoma
Contrast Enhanced Ultrasound Medical Imaging for Identifying Breast Masses
This clinical trial investigates the role of contrast enhanced ultrasound (CEUS) in identifying cystic breast masses as benign or malignant.
- Trial name
- NCT06171607
- Testing
- Contrast-Enhanced Ultrasound, Perflutren Lipid Microspheres, Sulfur Hexafluoride Lipid Microspheres
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Southern California
Sellar and Suprasellar Masses, Pituitary Tumor
Copeptin as a Biomarker for Central Diabetes Insipidus Development Following Pituitary Surgery
1. Access the optimal cut point value of copeptin which predicts development of central diabetes insipidus postoperatively with highest accuracy. 2.
- Trial name
- NCT04369703
- Where
- United States
- Volunteers
- 199 people
- Sponsor
- Mayo Clinic
Adnexal Masses, Ovarian Cysts
International Ovarian Tumour Analysis (IOTA) Phase 5
The purpose of this study is to learn more about the appearance and behavior of benign-looking adnexal masses. Benign-looking means that when viewed here by ultrasound it has the appearance of looking not harmful or not…
- Conditions
- Adnexal Masses, Ovarian Cysts, Ovarian Tumors
- Trial name
- IOTA-5 (NCT01698632)
- Where
- United States
- Volunteers
- 15,000 people
- Sponsor
- KU Leuven