Clinical trials: Mast Cell Stabilizer
Fibromyalgia
Novel Use of (Oral) Ketotifen for the Treatment of Fibromyalgia: A Pilot Study
The purpose of this 10-week study is to determine the effects of a medication called Ketotifen on pain sensitivity; and fibromyalgia-related pain.
- Trial name
- KetoforFMS (NCT01553318)
- Testing
- Ketotifen
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Indiana University
Rosacea
Efficacy and Safety of Tranilast Combined With Minocycline in the Treatment of Rosacea
Rosacea is a chronic inflammatory skin disease with a complex pathogenesis involving multiple factors. Currently, the treatment of rosacea remains highly challenging.
- Trial name
- NCT06307288
- Testing
- minocycline, tranilast
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Post-tick Bite Illness, Mast Cell Stabilizer
Mast Cell Treatment in Post-tick Bite Illness (PTBI)
This is a Phase II double-blinded study to assess the safety, tolerability, and feasibility of the mast cell stabilizing medications ketotifen and cromolyn compared to participants receiving standard of care treatment with…
- Trial name
- NCT07526558
- Testing
- Ketotifen, fexofenadine, Cromolyn Sodium
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Provoked Vestibulodynia, Secondary Provoked Vestibulodynia
Topical Ketotifen 0.25% for Secondary Vestibulodynia
This is a Phase 2, multi-center, randomized, double-blind, placebo-controlled trial evaluating the safety and efficacy of topical ketotifen fumarate 0.25% cream in adult women with secondary provoked vestibulodynia (PVD).
- Conditions
- Provoked Vestibulodynia, Secondary Provoked Vestibulodynia, Vulvodynia, Vulvary Pain Disorders
- Trial name
- NCT07257029
- Testing
- Ketotifen Fumarate 0.25% Cream
- Where
- 3 sites in United States
- Volunteers
- 54 people
- Sponsor
- Center for Vulvovaginal Disorders
Allergic Asthma
Pemirolast in Allergen Challenge (PEMAG)
The purpose of this study is to establish the influence of the non-steroidal candidate-drug pemirolast on allergen-induced airway obstruction and inflammation in allergic subjects with asthma.
- Trial name
- PEMAG (NCT03119714)
- Testing
- Pemirolast
- Where
- Sweden
- Volunteers
- 1 people
- Sponsor
- Karolinska University Hospital