Clinical trials: Mastectomy
Postoperative Pain
Comparison of ESP Block Versus Serratus Block
Total 60 patients, American society of anaesthesiology physical status I-II aged between 18-65 who underwent totally mastectomy will recruit to the study. The patients randomly divided into two groups.
- Trial name
- NCT03619447
- Testing
- ESP block group, serratus block group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cukurova University
IORT-Intra-Operative Radiation Therapy
Oncoplastic Partial Mastectomy With Intraoperative Radiation Therapy (IORT) in Early Stage Breast Cancer Patients With Prior History of Chest Wall Radiation.
Prospective, Non-randomized, Single-arm.The objectives of this study are to evaluate cosmesis and perioperative complications associated with the use of intraoperative radiotherapy (IORT) at the time of partial mastectomy in…
- Trial name
- NCT05289466
- Testing
- Intraoperative Radiotherapy, Oncoplastic partial mastectomy
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Saint John's Cancer Institute
Breast Cancer
Single vs. Double Drain in Modified Radical Mastectomy
Seroma is a common complication following modified radical mastectomy(MRM). Closed drainage is used routinely to reduce incidence of seroma.
- Trial name
- NCT02411617
- Testing
- Drain
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Memon Medical Institute
Post Operative Pain, Quality of Recovery After Mastectomy
Quality of Recovery From Mastectomy With and Without PECS Blocks
This is a prospective observational study. Investigators want to understand post-operative recovery for patients undergoing mastectomy at NorthShore University HealthSystem.
- Trial name
- NCT05795413
- Testing
- Mastectomy with PECS blocks, Liposomal bupivacaine
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Mastectomy and Breast Reconstruction, Sexual Wellness
Sexual Well-being of Women Undergoing Mastectomy and Reconstruction
The study plans to collect data from patients on sexual well-being after mastectomy and immediate reconstruction by surveys. This data can support preoperative patient counselling and the prevention and care of adverse effects of…
- Trial name
- NCT07234461
- Testing
- Survey using a questionnaire.
- Where
- 19 sites in Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- European Institute of Oncology
Injection Site Haematoma, Local Anesthetic Toxicity
U/S Guided SAPB Versus Conventional IV Analgesics in Postoperative Pain Management in MRM
The aim of this study is to compare the effect of ultra-sound guided serratus anterior plane block versus conventional IV analgesics in postoperative pain management in modified radical mastectomy (MRM)
- Trial name
- SAPB (NCT05126394)
- Testing
- ultrasound guided serratus anterior plane block
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain, Postoperative, Post-Mastectomy Chronic Pain Syndrome
Paravertebral Versus Pectoralis Block for Post Mastectomy Pain
Post-mastectomy pain affects more than half of patients undergoing the procedure and can last for years. It has been well established that development of chronic pain is related to experienced pain in the perioperative period.
- Conditions
- Pain, Postoperative, Post-Mastectomy Chronic Pain Syndrome, Opioid Use
- Trial name
- NCT03656679
- Testing
- Pectoralis Blockade (PECs), Paravertebral Blockade
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Breast-cancer
Seroma Formation After Modified Radical Mastectomy With Flap Fixation Technique in Breast Cancer Patients
The goal of this clinical trial is to evaluate the effectiveness of mastectomy flap fixation in breast cancer patients. The main questions it aims to answer are: To compare seroma formation after mastectomy flap fixation with…
- Trial name
- NCT06243796
- Testing
- Flap fixation technique
- Where
- Thailand
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nakhon Phanom Hospital
Anesthesia
Ultrasound-guided Serratus Plane Block for the Quality of Recovery After Modified Radical Mastectomy
Regional anesthesia improves quality of recovery after surgery in many studies. Ultrasound-guided serratus plane block is a novel technique which may be a viable alternative to current regional anesthetic techniques.
- Trial name
- NCT02691195
- Testing
- Ropivacaine, 0.9% Nacl
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Fujian Provincial Hospital
Anesthesia Awareness
TIVA vs Inhalational Mode of Anaesthesia
Sevoflurane based inhalational anaesthesia is the preferred mode of anesthesia for small duration cases. But in recent times, concept of rapid discharge, day care procedures, and green environment has created the need of new…
- Trial name
- NCT03807297
- Testing
- Injection dexmedetomidine, Injection, Propofol, 10 Mg, sevoflurane
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rajiv Gandhi Cancer Institute & Research Center, India
Genetic Predisposition, BRCA Mutation
Frequency of Occult Breast Cancer After Prophylactic Mastectomy Among High-Penetrance Breast Cancer Gene Positives
The role of Sentinel Lymph Node Biopsy(SLNB) among mutation-negative BC patients is well established; however, we are lacking data to assess the role of sentinel lymph node biopsy for patients who are undergoing surgery for…
- Conditions
- Genetic Predisposition, BRCA Mutation, Breast Cancer, Occult Cancer
- Trial name
- OBC-PM (NCT05771454)
- Testing
- Histopathological confirmation
- Where
- Pakistan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Aga Khan University Hospital, Pakistan
Reconstructive Surgical Procedures
The SurgiMend PRS Retrospective Study
The SurgiMend® PRS Retrospective Study will evaluate the performance and safety of SurgiMend® PRS and SurgiMend® PRS Meshed when used for soft tissue reinforcement under the product's indications for use.
- Trial name
- NCT05182177
- Testing
- SurgiMend PRS
- Where
- 6 sites in Italy, Switzerland and 1 more
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Integra LifeSciences Corporation
Breast Cancer
Cost-Effectiveness of Abdominal-based Autogenous Tissue vs Tissue Expander-Implant Reconstruction - A Feasibility Study
It is estimated that about 25% and 40% of health care expenditures in Canada and USA respectively are wasted because of inefficiencies and not practicing evidence-based medicine.
- Trial name
- NCT02438449
- Testing
- Breast Reconstruction Surgery
- Where
- Canada
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- McMaster University
Cancer
PECTORAL PLANE BLOCK COMPAIRED TO ERECTOR SPINAE PLANE BLOCK IN MULTIMODAL ANALGESIA FOR MASTECTOMY PATIENTS IN SOUTH ASIAN POPULATION -A PROSPECTIVE RANDOMISED CONTROL TRIAL
This prospective randomized controlled trial was conducted at the Department of Anesthesia, Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH\&RC), Lahore.
- Trial name
- NCT07197177
- Testing
- regional block
- Where
- Pakistan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
Breast Cancer, Breast Neoplasms
Study of the Safety of MRI Scans in People Who Have Breast Tissue Expanders After Mastectomy
The purpose of this study is to find out whether it is safe to perform MRI scans in people who have breast tissue expanders in place.
- Conditions
- Breast Cancer, Breast Neoplasms, Breast Adenocarcinoma
- Trial name
- NCT04769960
- Testing
- MRI Studies, Patient Reported Outcomes
- Where
- 3 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Esketamine and the Quality of Recovery
Esketamine Administration on Recovery Quality After Radical Mastectomy
Some studies have reported that intravenous esketamine reduce postoperative pain intensity. The investigators investigated whether esketamine could improve the the quality of recovery after modified radical mastectomy.
- Trial name
- NCT05289440
- Testing
- Low-dose esketamine infusion, High-dose esketamine infusion, Saline infusion
- Where
- China
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Anqing Municipal Hospital
Breast Neoplasms
Women Underwent TRAM Surgery: Its Influence on Abdominal Muscle Function and the Effects of Therapeutic Exercises
The unilateral transverse rectus abdominis musculocutaneous (TRAM) flap is a major operation widely used for breast reconstruction.
- Trial name
- NCT04886921
- Testing
- Abdominal muscle training
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Breast Cancer, BRCA Mutation
Tranexamic Acid Usage in Bilateral Mastectomy to Reduce Post-surgical Drainage
Tranexamic acid (TxA) is a drug that was approved by the FDA in 1986. It is an antifibrinolytic drug - this means that it is used to promote blood clotting by preventing the breakdown of blood clots that the participant's body…
- Trial name
- NCT05554211
- Testing
- Tranexamic acid, Normal saline
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
BREAST-Q
Validity and Reliability of Arabic Version of Breast Questionnaire
To test validity and reliability of the translated Arabic version of breast questionnaire .
- Trial name
- NCT05415033
- Testing
- BREAST-Q
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Cairo University
Breast/Surgery
Nipple-sparing Mastectomy in Combined With Buried Flap Monitoring
1. Learning curve of ms-Tram and DIEP breast reconstructions surgery are important to guide the training of new surgeon. 2. Buried flap post operative monitoring without implantable doppler was seldom studied, a validated…
- Trial name
- NCT05560633
- Testing
- No intervention
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University