Clinical trials: Mastectomy, open to volunteers
Breast Cancer, Anxiety
The Impact of AI- Supported Education in Mastectomy Patient
This study aims to evaluate the impact of artificial intelligence (AI)-supported preoperative education on fear and anxiety levels in patients undergoing total mastectomy.
- Conditions
- Breast Cancer, Anxiety, Mastectomy, Patient Education as Topic
- Trial name
- AI-ME (NCT06796166)
- Testing
- AI-Supported Preoperative Education, Standard Preoperative Education
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bezmialem Vakif University
Lymphedema, Mastectomy
Primary Surgical Prevention of Breast Cancer-related Lymphedema
Lymphedema refers to edema caused by insufficient drainage of interstitial fluid through the lymphatic circulation system. It occurs mainly in the upper and lower extremities and causes chronic inflammation, and finally fibrous…
- Conditions
- Lymphedema, Mastectomy, Breast Cancer
- Trial name
- LYMPHA (NCT04687956)
- Testing
- LYMPHA, control
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Gangnam Severance Hospital
Breast Cancer, Implant Breast Reconstruction
Hypofractionated vs. Conventionally Fractionated Postmastectomy Radiotherapy After Implant-Based Reconstruction
This is a prospective, randomized controlled, non-inferiority clinical trial designed to compare the outcomes of hypofractionated radiotherapy versus conventionally fractionated radiotherapy following mastectomy and implant-based…
- Trial name
- NCT07835139
- Testing
- ConvRT, HypoRT
- Where
- China
- Volunteers
- 534 people
- Sponsor
- Fudan University
Breast Cancer, Breast Reconstruction
Endoscopic Nipple-Sparing Mastectomy (E-NSM) With Immediate Multistage Autologous Fat Grafting(IMAFG) for Total Breast Reconstruction Via the Axillary Incision
The goal of this clinical study is to evaluate the effectiveness and safety of a novel breast reconstruction technique combining endoscopic nipple-sparing mastectomy (E-NSM) with immediate multistage fat grafting (IMFG) in female…
- Trial name
- NCT07352137
- Testing
- endoscopic nipple-sparing mastectomy (E-NSM) with immediate implant-based reconstruction
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Fascial Plane Block, Pain, Postoperative
Transverse vs. Longitudinal Serratus Anterior Plane Block in Breast Surgery
The aim of this prospective, randomized controlled trial is to compare the analgesic efficacy of transverse versus longitudinal ultrasound probe orientations during Serratus Anterior Plane (SAP) block in patients undergoing…
- Conditions
- Fascial Plane Block, Pain, Postoperative, Breast Surgery, Acute Pain
- Trial name
- NCT07739277
- Testing
- Transverse SAP Block, Longitudinal SAP Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ankara Etlik City Hospital
Post-mastectomy Pain Syndrome
Adding Magnesium Sulphate to Combined Pectointercostal Plane and Erector Spinae Plane Blocks for Acute and Chronic Post-Mastectomy Pain
Given the burden of chronic postmastectomy pain and the need for effective, opioid-sparing analgesia, the propose of the randomized controlled trial is to evaluate the safety and efficacy of adding magnesium sulphate to the…
- Trial name
- NCT07438366
- Testing
- Pectointercostal Plane Block (PIPB), Erector Spinae Plane Block (ESPB), Magnesium sulfate
- Volunteers
- 60 people
- Sponsor
- South Egypt Cancer Institute
Post Mastectomy Complications
Intercostal Mulligan Moblization Post Mastectomy
the study is to evaluate the therapeutic efficacy of intercostal mulligan Mobilization in decreasing pain and improve ROM for shoulder dysfunction Patients post mastectomy.
- Trial name
- NCT07181980
- Testing
- Intercostal mulligan mobilization with shoulder abduction, Exercise
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Radiotherapy, Breast Cancer
The Postoperative Radiotherapy in N1 Breast Cancer Patients
This study is a multicenter, randomized, phase 3 clinical trial in patients with breast cancer, randomizing radiotherapy group (postmastectomy radiation therapy (PMRT)/whole breast irradiation plus regional radiotherapy…
- Trial name
- PORT-N1 (NCT05440149)
- Testing
- No PMRT for mastectomy / No regional RT for BCS, PMRT for mastectomy / WBI + Regional RT for BCS
- Where
- South Korea
- Volunteers
- 1,106 people
- Sponsor
- Seoul National University Hospital
Breast Cancer Female, Breast Cancer Prevent
First-in-human, Study of MATTISSE® Tissue Engineering Chamber in Adult Female Patients Undergoing Breast Reconstruction After Mastectomy for Cancer
This study is a first in human, two-stage single arm non-comparative study of safety and performance. The aim of the study is to asses the safety and the clinical performance of a new device : the MATTISSE tissu engineering…
- Conditions
- Breast Cancer Female, Breast Cancer Prevent, Breast Reconstruction
- Trial name
- TIDE (NCT05460780)
- Testing
- MATTISSE TEC
- Where
- 3 sites in France, Georgia
- Volunteers
- 50 people
- Sponsor
- Quanta Medical
Breast Cancer
Prospective Cohort Study of Local Recurrence After Radical Breast Cancer Resection
The goal of this observational study is to analyze clinicopathological characteristics and identify independent prognostic risk factors, as well as compare treatment outcomes in female patients aged ≥18 years with pathologically…
- Trial name
- NCT07668362
- Testing
- Individualized therapy
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Breast Cancer Early Stage Breast Cancer (Stage 1-3), Mastectomy Patient
Impact of PErioperative Nutrition Intervention on Bioimpedance Phase Angle (IPENIPA) In Breast Cancer Patients
The goal of this clinical trial is to measure the mean difference of phase angle after nutritional intervention in breast cancer patients. The main question it aims to answer is: 1.
- Trial name
- IPENIPA (NCT06890221)
- Testing
- B-Crobes intake complete nutrition
- Where
- Malaysia
- Volunteers
- 114 people
- Sponsor
- University of Malaya
Breast Cancer, Radiotherapy Side Effect
Ultra-hypofractioNated Adjuvant Radiotherapy ± sImultaneous Integrated Boost for Low-risk Breast Cancer Patients
This is a phase II study to investigate the feasibility of Ultra-hypofractionated radiotherapy with or without simultaneous integrated boost for low risk breast cancer patients who have received breast conservative surgery of…
- Trial name
- UNIQUE (NCT05762900)
- Testing
- Ultra-fractionated radiation therapy
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Breast Neoplasms
Cold Dissection Versus Electrocautery Dissection in Endoscopic Nipple-Sparing Mastectomy and Immediate Implant-Based Reconstruction: A Randomized Controlled Trial
The purpose of this study is to analyze whether cold dissection can decrease the rate of ischemia necrosis and other complications and then increase the aesthetic outcomes compared to electrocautery.
- Trial name
- NCT06024187
- Testing
- Cold dissection, Electrocautery Dissection
- Where
- China
- Volunteers
- 566 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Breast Neoplasms, Mastectomy; Lymphedema
Self-Affirmation Intervention After Mastectomy
This randomized controlled trial aims to evaluate the effect of a structured self-affirmation intervention on pain, depression, anxiety, and stress levels in patients undergoing mastectomy.
- Conditions
- Breast Neoplasms, Mastectomy; Lymphedema, Pain, Depression
- Trial name
- NCT07355244
- Testing
- Positive Self-Affirmation Audio with Calming Background Sounds
- Volunteers
- 42 people
- Sponsor
- Muş Alparslan University
Breast Cancer, High Risk of Breast Cancer
Safety and Feasibility of Robotic SP Nipple Sparing Mastectomy
This is a single arm, single-center, prospective clinical trial designed to track the peri, post-operative and oncologic outcomes when utilizing the da-Vinci single port (SP) robotic platform to perform robotic nipple sparing…
- Trial name
- NCT05245812
- Testing
- da Vinci SP Surgical System
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Deborah Farr, MD
Breast Cancer, DCIS
Robotic Nipple Sparing Mastectomy with Immediate Reconstruction
Aim of this trial is to verify whether the patients' quality of life can be improved by a less invasive surgical procedure and whether the use of robotic technique for nipple-sparing mastectomy associated to prepectoral direct…
- Conditions
- Breast Cancer, DCIS, BRCA Mutation
- Trial name
- NCT06860217
- Testing
- Robotic Nipple-Sparing Mastectomy
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- European Institute of Oncology
Breast Cancer, Mastectomy; Lymphedema
Examining the Cosmetic Results, Quality of Life and Patient Satisfaction Achieved With Skin Reducing Nipple Sparing Mastectomy and Implant Based Breast Reconstruction, and Comparing it to Classic Skin- Sparing Mastectomy and Implant- Based Breast Reconstructive Surgeries
This is a response-adaptive (RAR) prospective randomized study with a long-term follow-up and the aim of this clinical study is to measure with qualitative and quantitative indicators the changes in cosmetic results, quality of…
- Conditions
- Breast Cancer, Mastectomy; Lymphedema, Quality of Life, Patient Satisfaction
- Trial name
- NCT04345081
- Testing
- Skin Reducing Nipple Sparing Mastectomy and Implant Based Breast Reconstruction, Skin- Sparing Mastectomy and Implant- Based Breast Reconstructive Surgery
- Where
- Hungary
- Volunteers
- 110 people
- Sponsor
- National Institute of Oncology, Hungary