Clinical trials: Mastectomy
Anesthesia Awareness
TIVA vs Inhalational Mode of Anaesthesia
Sevoflurane based inhalational anaesthesia is the preferred mode of anesthesia for small duration cases. But in recent times, concept of rapid discharge, day care procedures, and green environment has created the need of new…
- Trial name
- NCT03807297
- Testing
- Injection dexmedetomidine, Injection, Propofol, 10 Mg, sevoflurane
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rajiv Gandhi Cancer Institute & Research Center, India
Pain, Breast Cancer
Effect of Ketalar to Prevent Postoperative Chronic Pain After Mastectomy
Prevalence of chronic pain after mastectomy is beyond 50% 3 months after surgery. This pain is related to a sensitization of the central nervous system through N-methyl-D-asparate (NMDA) receptors.
- Trial name
- NCT00129597
- Testing
- ketalar
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Postoperative Pain, Breast Cancer
RISS Versus SPSIP Block in Modified Radical Mastectomy
This prospective randomized double-blind controlled trial aims to compare the postoperative analgesic efficacy and dermatomal spread of rhomboid intercostal-subserratus plane (RISS) block and serratus posterior superior…
- Trial name
- RSMRM (NCT07659990)
- Testing
- Rhomboid Intercostal-Subserratus Plane Block, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ferit Yetik
Post Mastectomy
Sensorimotor Training Exercises for Shoulder Position Sense
Forty-six female patients aged 35-55 years who were suffering from shoulder dysfunction following mastectomy surgeries participated in this study.
- Trial name
- NCT07316283
- Testing
- Sensorimotor Training Exercises, Traditional Physical Therapy Program
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Cairo University
Breast Cancer, Myofascial Trigger Point
Diagnosis and Management of Myofascial Pain Syndrome in Women With Mastectomies
Myofascial pain considerably affects women undergoing treatment for breast cancer, is characterized by the presence of myofascial taut bands and trigger points.
- Trial name
- NCT02181166
- Testing
- Kinesiotherapy, Isquemic compression, High voltage electrical stimulation
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Breast Cancer
Pasireotide LAR Administration in Lymphocele Prevention After Axillary Node Dissection for Breast Cancer
The principal morbidity following axillary node dissection within the scope of breast cancer surgery is the post-operative development of lymphocele.
- Trial name
- SOM 230 (NCT01356862)
- Testing
- PASIREOTIDE
- Where
- 2 sites in France
- Volunteers
- 91 people
- Sponsor
- Alliance Pour La Recherche en Cancerologie
Breast Cancer
Optimal Surgical Approach for Early-Stage Breast Cancer in Chinese Patients Aged ≤ 40 Years: a Cohort Study
The optimal surgical treatment option (BCS+RT versus MAST) for young patients with early-stage breast cancer remains debated. The present study aims to explore trends in surgical management and compare survival outcomes between…
- Trial name
- NCT06603805
- Testing
- MAST group, breast-conserving surgery plus adjuvant radiotherapy
- Volunteers
- 974 people
- Sponsor
- West China Hospital
Chronic Pain Syndrome
The Analgesic Efficacy Supra-scapular Nerve RF After Breast Surgery
Eighty patients with chronic shoulder pain after breast surgery were allocated randomly into 2 groups; forty patients received fluoroscopically guided supra-scapular nerve pulsed radiofrequency (PRF) followed by injection of…
- Trial name
- NCT03247842
- Testing
- suprascapular nerve block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Post-mastectomy Pain Syndrome
Evaluation and Re-evaluation of Post-mastectomy Pain Syndrome by Breast Cancer EDGE Task Force Outcomes
The purpose of the Breast Cancer EDGE Task Force is to provide physiotherapists with a comprehensive list of outcome measures that can be administered to a selected patient population, to assess post-mastectomy pain syndrome.
- Trial name
- NCT05458154
- Testing
- questionnaires
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Lymphocele
Use of Compression Bandages in the Prevention of Post-mastectomy Lymphoceles
Lymphocele secondary to a mastectomy whether or not associated with a lymph node procedure (sentinel lymph node or axillary dissection) is an almost systematic consequence observed in the postoperative situation in this type of…
- Trial name
- BANDOCELE (NCT04819542)
- Testing
- Bandage, No bandage
- Where
- France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Toulouse
Genetic Predisposition, BRCA Mutation
Frequency of Occult Breast Cancer After Prophylactic Mastectomy Among High-Penetrance Breast Cancer Gene Positives
The role of Sentinel Lymph Node Biopsy(SLNB) among mutation-negative BC patients is well established; however, we are lacking data to assess the role of sentinel lymph node biopsy for patients who are undergoing surgery for…
- Conditions
- Genetic Predisposition, BRCA Mutation, Breast Cancer, Occult Cancer
- Trial name
- OBC-PM (NCT05771454)
- Testing
- Histopathological confirmation
- Where
- Pakistan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Aga Khan University Hospital, Pakistan
Breast Reconstruction After Mastectomy, Neurotization
Longitudinal Evaluation of Direct Neurotization Technique in Breast Reconstruction With Fully Autologous Components
This clinical trial aims to evaluate whether direct neurotization using fully autologous components during autologous breast reconstruction improves postoperative breast sensation and sensory-related quality of life in women…
- Conditions
- Breast Reconstruction After Mastectomy, Neurotization, Mastectomy and Breast Reconstruction, Peripheral Nerve Regeneration
- Trial name
- NCT07308275
- Testing
- Autologous Breast Reconstruction With Direct Neurotization, Autologous Breast Reconstruction without Neurotization
- Where
- Indonesia
- Volunteers
- 28 people
- Sponsor
- Fakultas Kedokteran Universitas Indonesia
Breast Cancer, Pain
Pain After Tumescent Mastectomy or Standard Mastectomy in Women With Stage I, Stage II, or Stage III Breast Cancer
RATIONALE: New surgery techniques may lessen pain after breast surgery. It is not yet known whether tumescent mastectomy or standard mastectomy results in less pain in women with breast cancer.
- Conditions
- Breast Cancer, Pain, Perioperative/Postoperative Complications
- Trial name
- NCT00859157
- Testing
- therapeutic conventional surgery
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of California, Davis
Reconstructive Surgical Procedures
The SurgiMend PRS Retrospective Study
The SurgiMend® PRS Retrospective Study will evaluate the performance and safety of SurgiMend® PRS and SurgiMend® PRS Meshed when used for soft tissue reinforcement under the product's indications for use.
- Trial name
- NCT05182177
- Testing
- SurgiMend PRS
- Where
- 6 sites in Italy, Switzerland and 1 more
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Integra LifeSciences Corporation
Breast Cancer
Cost-Effectiveness of Abdominal-based Autogenous Tissue vs Tissue Expander-Implant Reconstruction - A Feasibility Study
It is estimated that about 25% and 40% of health care expenditures in Canada and USA respectively are wasted because of inefficiencies and not practicing evidence-based medicine.
- Trial name
- NCT02438449
- Testing
- Breast Reconstruction Surgery
- Where
- Canada
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- McMaster University
Stage I Breast Cancer, Stage II Breast Cancer
Comparison of Use of Indocyanine Green and 99mTc-labeled Radiotracer for Axillary Lymphatic Mapping in Patients With Breast Cancer
This clinical trial will enroll up to 130 adult women with a confirmed diagnosis of clinical stage 1 or 2 breast cancer who are undergoing breast cancer surgery with lumpectomy or mastectomy and planned axillary sentinel node…
- Trial name
- NCT02419807
- Testing
- Indocyanine Green Solution, Technetium Tc-99m Sulfur Colloid, Lymphoscintigraphy
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Case Comprehensive Cancer Center
Breast Cancer
A Novel Patient Decision Aid for Surgical Treatment Options in Early-Stage Breast Cancer
This is a study to assess the feasibility and acceptability of a novel decision aid (DA) in a newly diagnosed, early-stage breast cancer population.
- Trial name
- NCT06813053
- Testing
- Decision Aid (DA), Standard of Care (SOC)
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Gender Affirming Surgery, Mastectomy
Gender Affirming Mastectomy Analgesia Rial
Introduction: Optimizing pain management after gender-affirming mastectomy (removal of breast tissue, aka top surgery) surgery is important for recovery and minimizing opioid use.
- Conditions
- Gender Affirming Surgery, Mastectomy, Acute Pain
- Trial name
- GAMA (NCT07861165)
- Testing
- Paravertebral (single injection), Wide local infiltration
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Nova Scotia Health Authority
Pain, Postoperative
Study to Evaluate a Preop Dose of Brivoligide Injection for Pain After Mastectomy in Patients With High PCS Scores
This is a multiple center, randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of brivoligide injection administered intrathecally before surgery in patients with high Pain Catastrophizing Scale…
- Trial name
- NCT04104919
- Testing
- Brivoligide Injection 660 mg/6 mL
- Sponsor
- Adynxx, Inc.
Cancer
PECTORAL PLANE BLOCK COMPAIRED TO ERECTOR SPINAE PLANE BLOCK IN MULTIMODAL ANALGESIA FOR MASTECTOMY PATIENTS IN SOUTH ASIAN POPULATION -A PROSPECTIVE RANDOMISED CONTROL TRIAL
This prospective randomized controlled trial was conducted at the Department of Anesthesia, Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH\&RC), Lahore.
- Trial name
- NCT07197177
- Testing
- regional block
- Where
- Pakistan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre