Clinical trials: Masticatory Muscle Pain
Temporomandibular Disorders
Anterior Deprogrammers for Reducing Pain and Masticatory Muscles Tension
The study will be conducted in four groups of 20 patients in age of 20-30 years with complete dentition or single tooth loss in lateral regions, with masticatory muscle pain in the history or during examination and overuse and/or…
- Trial name
- Deprogrammer (NCT03180671)
- Testing
- Deprogramer Sliding Guide, Deprogrammer Dawson B-Splint, Deprogrammer Kois
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Lukasz Adamczyk
Myofacial Pain Syndrome
The Use of Botulinum Toxin in the Management of Myofascial Pain Syndrome
The objective of this study was to assess the efficacy of Botulinum toxin type (A) (BoNTA) injection in Myofascial pain syndrome management in the terms of duration of function improvement and pain reduction.
- Trial name
- NCT06824324
- Testing
- intramuscular Botulinum Toxin
- Where
- Iraq
- Volunteers
- 14 people
- Sponsor
- Yassir R. Al-khannaq
Myofascial Pain Syndrome, Temporomandibular Disorder
The Effectiveness of a Physiotherapy Technique in Patients With Chronic Myofascial Temporomandibular Disorder
Participants with chronic orofacial pain caused by masticatory and neck muscles will be distributed in two groups, both followed with the same occlusal and self-care treatment.
- Trial name
- TrP-TMD (NCT03619889)
- Testing
- Manual pressure release technique on trigger points.
- Where
- Spain
- Volunteers
- 74 people
- Sponsor
- Universidad Complutense de Madrid
Temporomandibular Disorder
K23- Physical Self Regulation vs Placebo
This study will use a between-person design. Participants will be treatment-seeking patients with chronic masticatory muscle pain.
- Trial name
- NCT06357702
- Testing
- Physical Self Regulation Telehealth, Psycho-education Telehealth
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Ian Boggero, PhD
Temporomandibular Joint, Temporomandibular Joint Dysfunction Syndrome
Effects of Masseter Manual Therapy on Temporomandibular Dysfunction
Muscles and myofascial dysfunction are more often the mechanism and source of pain in oral fascial disorders (OFD) than the TMJ.
- Conditions
- Temporomandibular Joint, Temporomandibular Joint Dysfunction Syndrome, Temporomandibular Joint Disorder
- Trial name
- NCT00870922
- Testing
- Active release techniques
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Logan College of Chiropractic
TMD
Low Level Laser Therapy Versus Pharmacotherapy in in Improving Masticatory Muscle Pain
tempromandibuar disorders are a group of heterogenous pathologies affecting temporomandibular joint,muscles or both.in more than 90%of cases muscles are the origin of pain.TMDs cause pain,movement disability and deficit in…
- Trial name
- NCT01659372
- Testing
- low level laser therapy, Naproxen
- Where
- 2 sites in Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University
Acute Apical Periodontitis of Pulpal Origin
Assessment of Masseter Muscle With Ultrasonography
In teeth that remain decayed for a long time, the muscles in that area atrophy because the patient cannot use the decayed area much. As a result, muscle length and mass decrease.
- Trial name
- NCT06734559
- Testing
- Patients who have not antibiotic treatment for acute apical periodontitis in the last month and have not taken any anti-inflammatory medication in the past 24 hours., patients who have not acute apical periodontitis
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Harran University
Myofascial Pain
PRGF Effectiveness for Myofascial Pain Treatment in Masticatory Muscles
The investigators set up a randomized controlled clinical trial to evaluate the effectiveness of plasma rich in growth factors (PRGF) injections into the masseter muscle trigger points for myofascial pain treatment.
- Trial name
- NCT04040309
- Testing
- PRGF injection, Lidocaine injection
- Where
- Lithuania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Pain
Assessment of Peripheral GABA Receptors for Local Pain Relief
The effect of peripheral GABAA receptor activation on pain and sensitivity in healthy human subjects has never been investigated.
- Trial name
- NCT02928328
- Testing
- GABA oral solution, Intramuscular GABA, Pain modulation
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Myofascial Pain - Dysfunction Syndrome of TMJ
Evaluation of the Effect of Occlusal Splint Use on Masticatory Muscles
"Female patients who applied to the 'Temporomandibular Disorders (TMD) Clinic' at the Department of Prosthodontics, Istanbul University Faculty of Dentistry, with complaints of muscle pain in the maxillofacial region and who are…
- Trial name
- NCT06675747
- Testing
- Ultrasound imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Istanbul University
Myofascial Pain Syndrome (MPS), Masticatory Muscle Pain
EMG-Based Evaluation of Occlusal Splint and Masseter Botox Effects on Head and Neck Muscles
This randomized controlled clinical trial aims to evaluate the individual and combined effects of occlusal splint therapy and botulinum toxin type A (BTX-A) injections into the masseter muscle on the activity of head and neck…
- Trial name
- NCT07082972
- Testing
- Botulinum toxin injection, Occlusal splint, Botulinum toxin + Occlusal splint combined
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Istanbul University
Neck Pain
Masseter Thickness, Bruxism, and Oral Behaviors in Chronic Neck Pain
A total of 30 patients aged 18-65 years who present with chronic non-specific neck pain and 30 healthy volunteers will be included in the study.
- Trial name
- NCT06874816
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Beylikduzu State Hospital
Temporomandibular Disorder, Myofascial Pain
CBD (Cannabidiol) Intraoral Application and TMD (Temporomandibular Disorders)
The aim of the project is to assess the effectiveness of reducing the masseter muscles tension and hyperactivity in patients with a painful form of TMD by using polymers containing CBD compared to placebo polymers.
- Conditions
- Temporomandibular Disorder, Myofascial Pain, Orofacial Pain, CBD
- Trial name
- NCT05562635
- Testing
- 5% polymer gel with CBD application, 10% polymer gel with CBD application
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
TMD, Masticatory Muscle Pain
Pain, Central Sensitization and Psychoemotional State in Patients With Chronic Masticatory Muscle Pain
The aim of this study is to investigate the relationship of psychological aspects, selected blood parameters, pain, central sensitization, and muscle electromyography activity in patients with chronic masticatory muscle pain.
- Trial name
- NCT05676827
- Testing
- Diagnostic Criteria for Temporomandibular Disorders Clinical Examination, Blood test
- Where
- Poland
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Pain, Postoperative
Investigating Temporalis and Masseter Botox Injection Before Orthognathic Surgery to Improve Postoperative Pain
Jaw surgery has become a very successful way to improve the appearance and functional needs of patients. Like any surgery, jaw surgery comes with a host of possible issues that patients may experience during their recovery.
- Trial name
- NCT04794504
- Testing
- Botox 100 UNT Injection, 0.9% Saline Injection
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Kingsway Oral & Maxillofacial Surgery
Myofacial Pain Syndrome, Local Myalgia
Effect of Occlusal Splint on Head and Neck Muscles in Patients With Bruxism and Myofascial Pain
The study group will be selected from patients who previously presented with various temporomandibular disorder (TMD) complaints to the "Temporomandibular Disorders Clinic" of the Department of Complete and Removable Dentures at…
- Conditions
- Myofacial Pain Syndrome, Local Myalgia, Masticatory Muscle Pain, Bruxism
- Trial name
- NCT07090551
- Testing
- occlusal splint therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Bruxism, Myofascial Pain
Botulinum Toxin Type A Versus Oral Ibuprofen for Bruxism
This randomized controlled trial evaluated the effectiveness of Botulinum Toxin Type A compared with oral ibuprofen in reducing pain and improving oral health-related quality of life in patients with sleep bruxism and jaw muscle…
- Trial name
- NCT07732751
- Testing
- Botulinum Toxin Type A 100U, Ibuprofen
- Where
- Cyprus
- Volunteers
- 40 people
- Sponsor
- Cyprus Health and Social Sciences University
Pain, Stomatognathic Diseases
The Effect of Different Physiotherapeutic Stimuli on Stomatognathic System Structures.
The study will determinate influence of four selected physiotherapeutic procedures on the pain intensity and the range of mandibular mobility in patients with myofascial disorders in the SS.
- Conditions
- Pain, Stomatognathic Diseases, Muscle Hypertonia, Myofacial Pain Syndromes
- Trial name
- NCT05021874
- Testing
- Four different physiotherapy treatment
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
TMJ Disc Disorder, Ultrasound Therapy; Complications
Ultrasound-Guided Vs Non-Guided Prolotherapy for Internal Derangement of Temporomandibular Joint. a Randomized Clinical Trial
Ultrasound Guided Versus Non-Guided Prolotherapy for Treatment of Internal Derangement of Temporomandibular joint. Rationale for conducting the research: The most critical cause for guided prolotherapy is to specify the accurate…
- Conditions
- TMJ Disc Disorder, Ultrasound Therapy; Complications, TMJ, Prolotherapy
- Trial name
- NCT05627830
- Testing
- Prolotherapy
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Myofacial Pain, Trigger Points, Myofascial
Comparison Between Botox and Magnesium Sulfate Effect in Treatment of Myofascial Pain Trigger Points Within the Masseter Muscle
The goal of this randomized clinical trial is to compare the effectiveness of Botulinum toxin type A, magnesium sulfate and saline injections in treatment of the masseter muscle trigger points, in patients between 16 - 50 years…
- Trial name
- MPS MTrPs BTA (NCT06676475)
- Testing
- MgSO4, BOTOX-A
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Misr University for Science and Technology