Clinical trials: Masticatory Myofascial Pain
Myofacial Pain Syndrome
The Use of Botulinum Toxin in the Management of Myofascial Pain Syndrome
The objective of this study was to assess the efficacy of Botulinum toxin type (A) (BoNTA) injection in Myofascial pain syndrome management in the terms of duration of function improvement and pain reduction.
- Trial name
- NCT06824324
- Testing
- intramuscular Botulinum Toxin
- Where
- Iraq
- Volunteers
- 14 people
- Sponsor
- Yassir R. Al-khannaq
Bruxism, Myofascial Pain
Ultrasonographic Evaluation of Masseter Muscle Changes After Botulinum Toxin Injection in Bruxism Patients
This prospective pilot study aimed to evaluate short-term clinical and ultrasonographic changes in the masseter muscle following botulinum toxin injection in patients with bruxism.
- Conditions
- Bruxism, Myofascial Pain, Masseter Muscle Hypertrophy
- Trial name
- NCT07545200
- Testing
- Botulinum Toxin A (Botox )
- Where
- Turkey (Türkiye)
- Volunteers
- 17 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Bruxism, Bruxism, Sleep
Effect of Marjoram, Vetiver, and Lavender Oil in the Treatment of Bruxism
The aim of this study was to investigate the possible effects of the use of lavender, marjoram and vetiver oil via inhalation and/or massage application on the treatment of bruxism.
- Conditions
- Bruxism, Bruxism, Sleep, Bruxism, Sleep-Related
- Trial name
- NCT07665398
- Testing
- Aromatherapy with Essential Oil Blend (Lavender, Marjoram, Vetiver), Carrier Oil (Sesame Oil)
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
TMJ Disc Disorder, Ultrasound Therapy; Complications
Ultrasound-Guided Vs Non-Guided Prolotherapy for Internal Derangement of Temporomandibular Joint. a Randomized Clinical Trial
Ultrasound Guided Versus Non-Guided Prolotherapy for Treatment of Internal Derangement of Temporomandibular joint. Rationale for conducting the research: The most critical cause for guided prolotherapy is to specify the accurate…
- Conditions
- TMJ Disc Disorder, Ultrasound Therapy; Complications, TMJ, Prolotherapy
- Trial name
- NCT05627830
- Testing
- Prolotherapy
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Temporomandibular Joint Dysfunction Syndrome, Chronic Pain
Restoring Masticatory Function to Treat Chronic Pain
The primary endpoint will be the average change in pain score from baseline to the three- and six-month assessments. Efficacy will be demonstrated by superior pain relief with the active treatment compared with the placebo.
- Trial name
- MAP (NCT02144233)
- Testing
- Occlusal adjustment
- Where
- 2 sites in Spain
- Volunteers
- 77 people
- Sponsor
- Urbano Santana Penin, MD, DDS, PhD
Bruxism, Temporomandibular Disorders (TMD)
Short-Term Symptom Changes in Adults With Teeth Clenching or Grinding and Jaw Symptoms Receiving Splint, Botulinum Toxin, or Medication Plus Splint Care
This prospective observational study evaluated short-term patient-reported symptom changes in adults with bruxism-related and temporomandibular disorder symptoms who received one of three clinically selected management…
- Conditions
- Bruxism, Temporomandibular Disorders (TMD), Myofascial Pain
- Trial name
- NCT07586072
- Testing
- Occlusal splint, Botulinum Toxin Type A (Dysport®), Thiocolchicoside
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Recep Tayyip Erdogan University
Masticatory Myofascial Pain
Effect Of Orofacial Pain Therapy On Bruxism
Bruxism and clenching at night and during the day are considered the most common parafunctions that can influence temporomandibular disorders, including chronic myofascial pain of the masticatory muscles.
- Trial name
- NCT07875738
- Where
- Italy
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Chronic Masticatory Myofascial Pain
Masticatory Muscle Activity Using a 24-Hour Wearable Device
Patients with chronic masticatory myofascial pain (MFP) often report that stress and parafunctional oral habits aggravate their pain, consistent with the widespread belief that stress and parafunctional habits lead to…
- Trial name
- NCT07861906
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Midwestern University
Myofacial Pain
Occlusal Splint and Masticatory Muscle Injection in Myofacial Pain
Myofascial pain is one of the common symptoms in patients with temporomandibular joint disorders. Occlusal splint use, trigger point injections and the combination of this two methods are primary treatment options.
- Trial name
- NCT05228327
- Testing
- Occlusal splint treatment, Masticatory muscle injection, Combination of occlusal splint and masticatory muscle injection treatments
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Masticatory Myofascial Pain Syndrome
MRI Study of OnabotulinumtoxinA (OnabotA) Effect on Jaw Muscle Pain
The goal of this clinical trial is to learn which magnetic resonance images are best able to assess and predict if a participant with masticatory myofascial pain syndrome will benefit from Botox injections, as compared to placebo…
- Trial name
- NCT07878780
- Testing
- Onabotulinumtoxin A
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Weill Medical College of Cornell University
Face Pain
Efficacy of Botulinum Toxin Versus Lidocaine in Treating Masticatory Myofascial Face Pain Using Ultrasound and EMG Guided Techniques
Botulinum toxin-A (BTX-A) prevents the release of acetylcholine in presynaptic terminals of the neuromuscular junction. It has been proposed to be effective in spastic conditions of the head and neck including oromandibular…
- Trial name
- NCT00992108
- Testing
- lidocaine, chemodenervation
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Myofascial Pain
PRGF Effectiveness for Myofascial Pain Treatment in Masticatory Muscles
The investigators set up a randomized controlled clinical trial to evaluate the effectiveness of plasma rich in growth factors (PRGF) injections into the masseter muscle trigger points for myofascial pain treatment.
- Trial name
- NCT04040309
- Testing
- PRGF injection, Lidocaine injection
- Where
- Lithuania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Muscle Type Temporomandibular Disorders, Myofascial Pain of the Masticatory Muscles
Myofascial Pain Patients' Response to the Administration of Low Doses of Amitriptyline and Citalopram Compared With the Use of Bite Splint
The aim of this study is evaluate the effectiveness of the use of antidepressants in the treatment of muscle type temporomandibular disorders, with a sample of 60 to 80 participants.
- Trial name
- NCT04777838
- Testing
- Citalopram 10 MG, Amitriptyline, Bite Splint
- Where
- Portugal
- Volunteers
- 80 people
- Sponsor
- University of Coimbra
Myofascial Pain Syndrome (MPS), Masticatory Muscle Pain
EMG-Based Evaluation of Occlusal Splint and Masseter Botox Effects on Head and Neck Muscles
This randomized controlled clinical trial aims to evaluate the individual and combined effects of occlusal splint therapy and botulinum toxin type A (BTX-A) injections into the masseter muscle on the activity of head and neck…
- Trial name
- NCT07082972
- Testing
- Botulinum toxin injection, Occlusal splint, Botulinum toxin + Occlusal splint combined
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Istanbul University
Masticatory Myofascial Pain Syndrome
Diffusion MRI for Quantitative Assessment of Myofascial Pain
The purpose of this study is to assess the diagnostic accuracy of diffusion MRI for evaluation of the jaw muscles for patients with masticatory myofascial pain syndrome.
- Trial name
- NCT06892041
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Myofascial Pain Syndromes
Effect of Lidocaine and Ozone in Injection for Myofascial Pain
Myofascial pain syndrome (MPS) is a chronic soft tissue rheumatism characterized by tense, painful muscle bands, known as trigger points, located within the muscle or fascia.
- Trial name
- NCT06768281
- Testing
- Headache Impact Test-6 (HIT-6), Pittsburgh Sleep Quality Index (PSQI), Visual Analogue Score (VAS)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yağmur Malkoc
Myofascial Pain Syndrome, Temporomandibular Disorder
The Effectiveness of a Physiotherapy Technique in Patients With Chronic Myofascial Temporomandibular Disorder
Participants with chronic orofacial pain caused by masticatory and neck muscles will be distributed in two groups, both followed with the same occlusal and self-care treatment.
- Trial name
- TrP-TMD (NCT03619889)
- Testing
- Manual pressure release technique on trigger points.
- Where
- Spain
- Volunteers
- 74 people
- Sponsor
- Universidad Complutense de Madrid
Temporomandibular Disorder, Myofascial Pain
Myorelaxant Effect of Cannabis Cream Topical Skin Application in Patients With TMD
Evaluation of myorelaxant effect of cannabis cream.compared to placebo cream in topical skin application in patients with TMD
- Conditions
- Temporomandibular Disorder, Myofascial Pain, Cannabis, Electromyography
- Trial name
- NCT03994640
- Testing
- Cannabis Cream
- Where
- Poland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Myofacial Pain Syndrome, Local Myalgia
Effect of Occlusal Splint on Head and Neck Muscles in Patients With Bruxism and Myofascial Pain
The study group will be selected from patients who previously presented with various temporomandibular disorder (TMD) complaints to the "Temporomandibular Disorders Clinic" of the Department of Complete and Removable Dentures at…
- Conditions
- Myofacial Pain Syndrome, Local Myalgia, Masticatory Muscle Pain, Bruxism
- Trial name
- NCT07090551
- Testing
- occlusal splint therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Myofascial Pain - Dysfunction Syndrome of TMJ
Efficiency of Botulinum Toxin type-a in the Management of the Myofascial Pain
Study Title: Investigation of the Relationship Between Clinical Outcomes and Pain Mediators in the Treatment of Masticatory Muscle Disorders Associated with Myospasm Using Onabotulinum Toxin A Study Importance: Temporomandibular…
- Trial name
- NCT06840730
- Testing
- Botulinum Toxin A (Botox )
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Hacettepe University