Clinical trials: Mastitis
Mastitis
Ductal Lavage in Non-lactating Female Women With Mastitis
RATIONALE and PURPOSE: For non-lactational mastitis patients pathologically diagnosis of idiopathic granulomatous mastitis (IGM) or periductal mastitis (PD), the investigators hypothesized that ductal lavage is able to relieve…
- Trial name
- NCT02794688
- Testing
- Ductal lavage therapy
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Mastitis Acute Female
The Effect of Chinese Herbal Medicine for Reducing the Application of Antibiotics in the Treatment of Acute Mastitis
The object of the study is to evaluate the effect of Pugongying (Herba Taraxaci) Granules to reduce the application of antibiotics for women with acute mastitis.
- Trial name
- NCT03756324
- Testing
- CHPM (Chinese Herbal Patent Medicine ), Antibiotics Cefdinir Capsules, Education
- Where
- 3 sites in China
- Volunteers
- 306 people
- Sponsor
- Beijing University of Chinese Medicine
Mastitis Chronic, Idiopathic Granulomatous Mastitis
Baricitinib in Idiopathic Granulomatous Mastitis
This study will explore the mechanism of targeted drug in treatment of idiopathic granulomatous mastitis, and clarify the clinical classification and corresponding markers.
- Trial name
- B-IGM (NCT05852171)
- Testing
- Baricitinib
- Where
- China
- Volunteers
- 20 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Idiopathic Granulomatous Mastitis, Granulomatous Mastitis
GRAnulomatous MAstitis REGistry Study
Idiopathic granulomatous mastitis (IGM) is a rare benign inflammatory breast condition with unknown cause, affecting approximately 2.4 per 100,000 women aged 20-40 years.
- Trial name
- GRAMAREG (NCT07422870)
- Where
- 2 sites in Germany
- Volunteers
- 1,000 people
- Sponsor
- European Breast Cancer Research Association of Surgical Trialists
Refractory Granulomatous Lobular Mastitis
Surgical Intervention for Refractory Granulomatous Lobular Mastitis
Granulomatous lobular mastitis (GLM) belongs to a group of benign diseases, which is mainly treated with glucocorticoids and surgical treatment.
- Trial name
- NCT04637711
- Testing
- Focus clearing + whole breast exploration and washing + one-stage micro plastic surgery No Intervention: Extensive lesion excision
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Wuhan University
Idiopathic Granulomatous Mastitis
Steroid Injection in Idiopathic Granulomatous Mastitis
Granulomatous mastitis (GM) is a non-infectious inflammatory breast condition typically affecting young women, often following breastfeeding. Management of GM often begins with anti-inflammatory medications and antibiotics.
- Trial name
- NCT06985537
- Testing
- Ultrasound guided intralesional Steroids injection (Triamicinolone)
- Volunteers
- 40 people
- Sponsor
- Assiut University
Mastitis
Study of Acupuncture and Care Interventions for the Treatment of Breast Inflammation During Breastfeeding
The objective of the study was to test the hypothesis that acupuncture treatment hastens recovery time from inflammatory symptoms of the breast during breastfeeding.
- Trial name
- NCT00405158
- Testing
- Acupuncture treatment, Administration of oxytocin nasal spray, Improved breast milk removal
- Where
- Sweden
- Volunteers
- 210 people
- Sponsor
- Karlstad University
Tongue Tie, Ankyloglossia
The Scope of Tongue-tie in Norway: Its Prevalence and Consequences for Child Health
The study is a prospective multi-centre clinical follow-up study of prevalence and severity of tongue-tie in neonates in Norway.
- Trial name
- NCT04056936
- Testing
- Frenotomy
- Volunteers
- 100 people
- Sponsor
- University of Oslo
Mastitis Postpartum
Optimizing Mastitis Identification and Treatment
The goal of this observational study is to gain more information about the aetiology and progression of mastitis and breast inflammation, in order to develop evidence-based clinical guidelines and treatment plans, especially…
- Trial name
- OPTIMIST (NCT05794945)
- Where
- 2 sites in Norway
- Volunteers
- 300 people
- Sponsor
- University of Tromso
Postpartum Complication
IMPACT: Improving Maternal Postpartum Access to Care Through Telemedicine
The purpose of this study is to compare two complex, multi-component evidence-based postpartum interventions in underserved populations of lower socioeconomic status in an effort to reduce maternal morbidity and mortality.
- Trial name
- IMPACT (NCT06218355)
- Testing
- Intensive Education, Enhanced Virtual Care
- Where
- 2 sites in United States
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Idiopathic Granulomatous Mastitis
Comparing Effectiveness of Steroids and Methotrexate in Treatment of Chronic Inflammatory Breast Disease
This research study is to determine the effectiveness of prednisolone and methotrexate for IGM patients over a period of one year, in terms of clinical and radiological response.
- Trial name
- IGM (NCT06943482)
- Testing
- Prednisolone, Methotrexate, Folic Acid 5 MG
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- National University Hospital, Singapore
Mastitis
Use of Probiotic Lactobacilli for the Treatment of Lactational Mastitis
A total of 300 women with lactational infectious mastitis will daily ingest 9 log10 cfu of Lactobacillus salivarius HN6, Lactobacillus reuteri CR20 or Lactobacillus fermentum LC40 for 4 weeks.
- Trial name
- NCT00716183
- Testing
- Lactobacillus salivarius HN6, Lactobacillus reuteri CR20, Lactobacillus fermentum LC40
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Universidad Complutense de Madrid
Breast-conserving Plastic Surgery, Granulomatous Mastitis
Effect of Different Surgical Approaches of Granulomatous Mastitis
The objective of this study was to prospectively investigate the effects of different surgical approaches on the recurrence rate and aesthetic outcome of patients with granulomatous mastitis.
- Trial name
- NCT06712524
- Testing
- Breast-conserving plastic surgery, Traditional breast surgery
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Hubei Cancer Hospital
Mastitis
Study of a Probiotic Strain to Prevent Mastitis and to Eradicate GBS Colonization
In previous studies, the investigators have seen that carefully-selected Lactobacillus strains are a good alternative to antibiotics for the treatment of lactational mastitis.
- Trial name
- PROBIOPREG (NCT01505361)
- Testing
- Lactobacillus salivarius PS2, Excipient (milk powder)
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Breast Infection
Outcomes of a Novel Technique of Mini- Incision and Self-Express (MISE) for Breast Abscess
Conventional techniques for treatment of breast abscess, such as incision and drainage/percutaneous drainage, have disadvantages. Bedside Mini-Incision and Self-Express (MISE) is a novel technique for breast abscess.
- Trial name
- NCT05762016
- Testing
- Bedside Mini-Incision and Self-Express (MISE)
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- KK Women's and Children's Hospital
Granulomatous Mastitis
Immune Cells in Patients With Granulomatous Mastitis
Granulomatous mastitis is a rare, chronic, benign inflammatory disease of the breast that plays a role in many varying etiologies, including infectious and non-infectious causes.
- Trial name
- NCT04543149
- Testing
- Flow cytometric immunophenotyping
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Breast Feeding, Mastitis
Identification of Biomarkers of Mastitis
Breastfeeding is the optimal feeding for infants. WHO currently promotes breastfeeding and recommends it to be exclusive until the baby is 6 months old.
- Conditions
- Breast Feeding, Mastitis, Mastitis Acute Female
- Trial name
- NCT05021042
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- LactApp Women's Health
Mastitis
Osteopathic Manipulative Treatment for Recurrent Mastitis
This study will investigate whether Osteopathic Manipulative Treatment (OMT) is effective in treating recurrent mastitis without the use of antibiotics and if it helps in preventing future recurrence of mastitis in individuals…
- Trial name
- NCT05132426
- Testing
- Osteopathic Manipulative Treatment (OMT)
- Where
- United States
- Sponsor
- Western University of Health Sciences
Plasma Cell Mastitis
A Single Arm Study of Traditional Chinese Medicine for Plasma Cell Mastitis
This is a single-center, single-arm, open-label trial evaluating the efficacy and safety of traditional Chinese medicine for plasma cell mastitis.
- Trial name
- NCT05530226
- Testing
- Traditional Chinese medicine
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shengjing Hospital
Mastitis, Breast Milk
Effect of Probiotics Consumed During Pregnancy on the Incidence of Mastitis
The aim of the present study is to evaluate the effect of consumption during pregnancy and the lactation period of the probiotic L. fermentum CECT5716 on the incidence of mastitis.
- Conditions
- Mastitis, Breast Milk, Lactation, Women's Health
- Trial name
- NCT04032899
- Testing
- Lactobacillus fermentum CECT5716, Maltodextrin
- Where
- 3 sites in Spain
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Biosearch S.A.