Clinical trials: Mastitis
Granulomatous Mastitis
Could Intralesional Steroid be the Novel Treatment for Granulomatous Mastitis?
Idiopathic granulomatous mastitis (IGM) is a rare, benign inflammatory breast disease that mimics malignancy owing to its features of appearance.In our research, we intended to compare the efficiency of local (intralesional)…
- Trial name
- IGM (NCT04596046)
- Testing
- steroid injecting
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Granulomatous Mastitis
Analysis of Various Treatment Methods of Granulomatous Lobular Mastitis
Granulomatous lobular mastitis (GLM) is a rare benign breast disease that is difficult to distinguish from breast cancer based on clinical and imaging findings, and there is currently no standard treatment.
- Trial name
- NCT06565845
- Testing
- Surgery, triple anti-tuberculosis drug
- Where
- China
- Volunteers
- 350 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Mastitis
Study of a Probiotic Strain to Prevent Mastitis and to Eradicate GBS Colonization
In previous studies, the investigators have seen that carefully-selected Lactobacillus strains are a good alternative to antibiotics for the treatment of lactational mastitis.
- Trial name
- PROBIOPREG (NCT01505361)
- Testing
- Lactobacillus salivarius PS2, Excipient (milk powder)
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Mastitis
Effect of a Nursing Teaching Protocol on Mastitis Prognosis: Quasi-Experimental Research Design
Aim: Evaluate the effect of a nursing teaching protocol on mastitis prognosis. Research design: Quasi-experimental research design was utilized.
- Trial name
- Mastitis (NCT05974956)
- Testing
- Mastitis care teaching protocol
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postpartum Complication
IMPACT: Improving Maternal Postpartum Access to Care Through Telemedicine
The purpose of this study is to compare two complex, multi-component evidence-based postpartum interventions in underserved populations of lower socioeconomic status in an effort to reduce maternal morbidity and mortality.
- Trial name
- IMPACT (NCT06218355)
- Testing
- Intensive Education, Enhanced Virtual Care
- Where
- 2 sites in United States
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Mastitis
Physical Therapy Intervention for Puerperal Mastitis
Puerperal mastitis is one of the most commonly reported problems during breastfeeding. Women frequently report breast pain, tenderness, redness, engorgement, fever, malaise, chills, lethargy, sweating, headache, nipple damage and…
- Trial name
- NCT04569136
- Testing
- Education, Therapeutic ultrasound, Breast massage
- Where
- Taiwan
- Volunteers
- 37 people
- Sponsor
- National Cheng Kung University
Breast Pain
L.Fermentum CECT5716 in Treatment of Breast Pain
The main objective of this intervention study is to evaluate the efficacy of Lactobacillus fermentum CECT5716 to reduce the presence in the milk of genera Staphylococcus and Streptococcus as risk factors for mastitis in women…
- Trial name
- NCT02093338
- Testing
- Lactobacillus fermentum CECT5716
- Where
- Spain
- Volunteers
- 127 people
- Sponsor
- Biosearch S.A.
Granulomatous Mastitis
Immune Cells in Patients With Granulomatous Mastitis
Granulomatous mastitis is a rare, chronic, benign inflammatory disease of the breast that plays a role in many varying etiologies, including infectious and non-infectious causes.
- Trial name
- NCT04543149
- Testing
- Flow cytometric immunophenotyping
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Granulomatous Mastitis
Ductal Lavage Versus Corticosteroids Therapy for Idiopathic Granulomatous Mastitis
A single-arm, proof-of-concept trial has shown the safety and efficacy of ductal lavage as a treatment for idiopathic granulomatous mastitis patients (Manuscript accepted in Journal of Surgical Research 2018).
- Trial name
- NCT03724903
- Testing
- Ductal lavage, Corticosteroid therapy
- Where
- 2 sites in China
- Volunteers
- 140 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Granulomatous, Mastitis
Granulomatous Mastitis Current Approach and Treatment
The aim of this study was to retrospectively review the granulomatous mastitis and evaluated current approach and treatment. HYPOTHESIS Although there is no common protocol for the treatment and management process of GM, the…
- Trial name
- NCT02667132
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Granulomatous Mastitis Working Group
Plasmacytic Mastitis, Granulomatous Lobular Mastitis
Efficacy and Safety of Sanyong Jiedu Granules in Treating Lumps-Type Non-Lactational Mastiti
To evaluate the efficacy and safety of Sanyong Jiedu Granules in treating non-lactational mastitis with lump formation, and to investigate the relationship between its clinical efficacy and treatment duration.
- Trial name
- NCT07512648
- Testing
- Sanyong Jiedu Granules, Standard Medication
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Caigang Liu
Breast Infection
Painful Breastfeeding and Bacterial or Yeast Infection
The aim of this study is to investigate the prevalence of yeast and bacteria in women with breastfeeding pain and to identify signs and symptoms.
- Trial name
- NCT01631461
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Refractory Granulomatous Lobular Mastitis
Combined Intralesional Triamcinolone Injection With Whole Breast Detection Radical Surgery
Granulomatous lobular mastitis (GLM) is a rare, chronic benign inflammatory disease of the breast, of unknown etiology. Pathologically, GLM typically manifests as non-caseating granulomatous lesions with leukomonocytes…
- Trial name
- NCT05281419
- Testing
- Intralesional triamcinolone injection, No intralesional triamcinolone injection
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Wuhan University
Mastitis Postpartum
Optimizing Mastitis Identification and Treatment
The goal of this observational study is to gain more information about the aetiology and progression of mastitis and breast inflammation, in order to develop evidence-based clinical guidelines and treatment plans, especially…
- Trial name
- OPTIMIST (NCT05794945)
- Where
- 2 sites in Norway
- Volunteers
- 300 people
- Sponsor
- University of Tromso
Idiopathic Granulomatous Mastitis
Risk Factors and the Role of Albumin-to-globulin Ratio in Idiopathic Granulomatous Mastitis
Albumin-to-globulin ratio (AGR) is an inflammation-based index that has been shown to have a role in many cancers and inflammatory diseases.
- Trial name
- NCT05409586
- Testing
- segmental mastectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people
- Sponsor
- Samsun Education and Research Hospital
Breast-conserving Plastic Surgery, Granulomatous Mastitis
Effect of Different Surgical Approaches of Granulomatous Mastitis
The objective of this study was to prospectively investigate the effects of different surgical approaches on the recurrence rate and aesthetic outcome of patients with granulomatous mastitis.
- Trial name
- NCT06712524
- Testing
- Breast-conserving plastic surgery, Traditional breast surgery
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Hubei Cancer Hospital
Refractory Granulomatous Lobular Mastitis
Surgical Intervention for Refractory Granulomatous Lobular Mastitis
Granulomatous lobular mastitis (GLM) belongs to a group of benign diseases, which is mainly treated with glucocorticoids and surgical treatment.
- Trial name
- NCT04637711
- Testing
- Focus clearing + whole breast exploration and washing + one-stage micro plastic surgery No Intervention: Extensive lesion excision
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Wuhan University
Mastitis Acute Female
The Effect of Chinese Herbal Medicine for Reducing the Application of Antibiotics in the Treatment of Acute Mastitis
The object of the study is to evaluate the effect of Pugongying (Herba Taraxaci) Granules to reduce the application of antibiotics for women with acute mastitis.
- Trial name
- NCT03756324
- Testing
- CHPM (Chinese Herbal Patent Medicine ), Antibiotics Cefdinir Capsules, Education
- Where
- 3 sites in China
- Volunteers
- 306 people
- Sponsor
- Beijing University of Chinese Medicine
Granulomatous Mastitis
Antibiotics vs Corticosteroids in Treatment of Granulomatous Lobular Mastitis
The goal of this clinical trial is to find the most effective and safe medical treatment for Granulomatous Lobular Mastitis (GLM) - a rare, chronic inflammatory breast disease that affects young and middle-aged women, often…
- Trial name
- GRANMAS (NCT07454772)
- Testing
- Steroid, Antibiotic
- Where
- India
- Volunteers
- 72 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Mastitis
Use of Probiotic Lactobacilli for the Treatment of Lactational Mastitis
A total of 300 women with lactational infectious mastitis will daily ingest 9 log10 cfu of Lactobacillus salivarius HN6, Lactobacillus reuteri CR20 or Lactobacillus fermentum LC40 for 4 weeks.
- Trial name
- NCT00716183
- Testing
- Lactobacillus salivarius HN6, Lactobacillus reuteri CR20, Lactobacillus fermentum LC40
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Universidad Complutense de Madrid