Clinical trials: Mastitis, open to volunteers
Idiopathic Granulomatous Mastitis, Granulomatous Mastitis
GRAnulomatous MAstitis REGistry Study
Idiopathic granulomatous mastitis (IGM) is a rare benign inflammatory breast condition with unknown cause, affecting approximately 2.4 per 100,000 women aged 20-40 years.
- Trial name
- GRAMAREG (NCT07422870)
- Where
- 2 sites in Germany
- Volunteers
- 1,000 people
- Sponsor
- European Breast Cancer Research Association of Surgical Trialists
Refractory Granulomatous Lobular Mastitis
Surgical Intervention for Refractory Granulomatous Lobular Mastitis
Granulomatous lobular mastitis (GLM) belongs to a group of benign diseases, which is mainly treated with glucocorticoids and surgical treatment.
- Trial name
- NCT04637711
- Testing
- Focus clearing + whole breast exploration and washing + one-stage micro plastic surgery No Intervention: Extensive lesion excision
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Wuhan University
Idiopathic Granulomatous Mastitis
Steroid Injection in Idiopathic Granulomatous Mastitis
Granulomatous mastitis (GM) is a non-infectious inflammatory breast condition typically affecting young women, often following breastfeeding. Management of GM often begins with anti-inflammatory medications and antibiotics.
- Trial name
- NCT06985537
- Testing
- Ultrasound guided intralesional Steroids injection (Triamicinolone)
- Volunteers
- 40 people
- Sponsor
- Assiut University
Mastitis Postpartum
Optimizing Mastitis Identification and Treatment
The goal of this observational study is to gain more information about the aetiology and progression of mastitis and breast inflammation, in order to develop evidence-based clinical guidelines and treatment plans, especially…
- Trial name
- OPTIMIST (NCT05794945)
- Where
- 2 sites in Norway
- Volunteers
- 300 people
- Sponsor
- University of Tromso
Postpartum Complication
IMPACT: Improving Maternal Postpartum Access to Care Through Telemedicine
The purpose of this study is to compare two complex, multi-component evidence-based postpartum interventions in underserved populations of lower socioeconomic status in an effort to reduce maternal morbidity and mortality.
- Trial name
- IMPACT (NCT06218355)
- Testing
- Intensive Education, Enhanced Virtual Care
- Where
- 2 sites in United States
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Idiopathic Granulomatous Mastitis
Comparing Effectiveness of Steroids and Methotrexate in Treatment of Chronic Inflammatory Breast Disease
This research study is to determine the effectiveness of prednisolone and methotrexate for IGM patients over a period of one year, in terms of clinical and radiological response.
- Trial name
- IGM (NCT06943482)
- Testing
- Prednisolone, Methotrexate, Folic Acid 5 MG
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- National University Hospital, Singapore
Breast-conserving Plastic Surgery, Granulomatous Mastitis
Effect of Different Surgical Approaches of Granulomatous Mastitis
The objective of this study was to prospectively investigate the effects of different surgical approaches on the recurrence rate and aesthetic outcome of patients with granulomatous mastitis.
- Trial name
- NCT06712524
- Testing
- Breast-conserving plastic surgery, Traditional breast surgery
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Hubei Cancer Hospital
Non-Puerperal Mastitis
Ablation Versus Non-ablation Strategies for Non-puerperal Mastitis: A Prospective Real-world Registry Study
The goal of this prospective registry cohort study is to evaluate the efficacy and quality-of-life impact of ablation therapy in patients with non-puerperal mastitis.
- Trial name
- NCT07894614
- Testing
- Ablation, Observation
- Where
- China
- Volunteers
- 340 people
- Sponsor
- Song Hongping
Plasmacytic Mastitis, Granulomatous Lobular Mastitis
Efficacy and Safety of Sanyong Jiedu Granules in Treating Lumps-Type Non-Lactational Mastiti
To evaluate the efficacy and safety of Sanyong Jiedu Granules in treating non-lactational mastitis with lump formation, and to investigate the relationship between its clinical efficacy and treatment duration.
- Trial name
- NCT07512648
- Testing
- Sanyong Jiedu Granules, Standard Medication
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Caigang Liu
Breast Diseases, Mastitis Granulomatous
A Randomized Controlled Study of Conservative Treatment of Granulomatous Lobular Mastitis Combined With Psychiatric Disorders
Granulomatous lobular mastitis (GLM) is a relatively rare chronic inflammatory disease of the breast in clinical practice. A small number of patients develop hyperprolactinemia during psychiatric drug treatment, and most of these…
- Conditions
- Breast Diseases, Mastitis Granulomatous, Psychiatric Disorder
- Trial name
- GLMwPD (NCT05395949)
- Testing
- conservative treatment
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Wuhan University
Breast Abscess
Evaluation of Non-Surgical Treatment of Breast Abscess
Breast abscess is a localized suppurative complication of breast infection commonly managed by ultrasound-guided needle aspiration combined with antibiotic therapy.
- Trial name
- NCT07777783
- Testing
- Ultrasound-guided needle aspiration and antibiotics
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Granulomatous Mastitis
Antibiotics vs Corticosteroids in Treatment of Granulomatous Lobular Mastitis
The goal of this clinical trial is to find the most effective and safe medical treatment for Granulomatous Lobular Mastitis (GLM) - a rare, chronic inflammatory breast disease that affects young and middle-aged women, often…
- Trial name
- GRANMAS (NCT07454772)
- Testing
- Steroid, Antibiotic
- Where
- India
- Volunteers
- 72 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Granulomatous Lobular Mastitis, Granulomatous Mastitis
Tocilizumab for the Treatment of Refractory Granulomatous Lobular Mastitis
Non-Lactational Granulomatous Lobular Mastitis (NL-GLM) is an inflammatory disease of unknown etiology, characterized clinically by local breast masses, accompanied by redness and swelling of the overlying skin, sinus tract…
- Trial name
- NCT07595900
- Testing
- Tocilizumab
- Volunteers
- 31 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Maternal Health Services, Infant, Newborn
Comparing Integrative Midwife-led vs. Fragmented Inpatient Postpartum Care: Impact on Satisfaction and Transition to Motherhood
The goal of this clinical trial is to compare two different forms of postnatal care to find out which is most beneficial for mothers and their children after birth and with which they are most satisfied.
- Conditions
- Maternal Health Services, Infant, Newborn, Postnatal Care, Breast Feeding
- Trial name
- SMILE (NCT07077941)
- Testing
- Integrative care
- Where
- Austria
- Volunteers
- 784 people
- Sponsor
- Medical University of Vienna