Clinical trials: Mastodynia
Pain Syndrome, Pain, Postoperative
The Impact of Pecs Blocks on Postmastectomy Pain Syndrome
The aim of the present study is to investigate the incidence of chronic pain following breast cancer surgery in Cyprus, discover its associated risk factors and explore the impact of Pecs Blocks on the appearance of post…
- Conditions
- Pain Syndrome, Pain, Postoperative, Chronic Pain, Breast Cancer
- Trial name
- NCT04586751
- Testing
- Pecs block, no Pecs block
- Where
- 3 sites in Cyprus, Greece
- Volunteers
- 64 people
- Sponsor
- Aretaieion University Hospital
Breast Cancer, Breast Pain
Post Mastectomy Pain Syndrome After Preoperative Stellate Ganglion Block for Breast Cancer Surgeries
This study investigate the effect of pre-operative ultrasound guided stellate ganglion block with local anesthetic on the frequency of neuropathic pain syndromes in the first 6-month post cancer breast surgeries with axillary…
- Trial name
- NCT04238377
- Testing
- Stellate Ganglion Block, Multimodal Analgesia
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- National Cancer Institute, Egypt
Breast Cancer
The Effect of Metoprolol on Anaesthesia, the Need for Analgesics, and Pain in Breast Cancer Patients
The purpose of the study is to test the effects of metoprolol on anaesthesia and the need for perioperative analgesics in patients undergoing breast surgery.
- Trial name
- NCT02269696
- Testing
- Metoprolol, Normal saline
- Sponsor
- Kuopio University Hospital
Mastalgia
A New Treatment Option for Mastalgia
The main objective of this study is to determine the effectiveness of transcutaneous electrical nerve stimulation (TENS) treatment on pain and quality of life in mastalgia, which treatment has not yet reached a consensus.
- Trial name
- NCT06168110
- Testing
- TENS
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Ankara University
Fibrocystic Breast Condition (FBC)
A Randomized Double-blind, Placebo Controlled, Multi-center Study to Evaluate the Safety, Tolerability and Potential Effects of the Dietary Supplement Violet™ Molecular Iodine (I2) on Breast Health in Women With Cyclic Breast Discomfort and Tenderness
This is a randomized, double-blind, placebo controlled, multi-center study to evaluate the safety, tolerability and potential effects of dietary supplement Violet™ Iodine on breast health in women with cyclic breast discomfort…
- Trial name
- NCT02676336
- Testing
- Violet™ Molecular Iodine (I2)
- Where
- 2 sites in United States, Canada
- Volunteers
- 31 people
- Sponsor
- BioPharmX, Inc.
Breast Disease, Breast Neoplasms
Pattern of Clinical Presentation of Different Breast Disease in Surgical Opd at BPKIHS
Research Title PATTERN OF CLINICAL PRESENTATION OF DIFFERENT BREAST DISEASE IN SURGICAL OPD AT BPKIHS Rationale: The Study will help us to know about pattern of presentation of different breast diseases Aims and Objectives: 1.
- Conditions
- Breast Disease, Breast Neoplasms, Breast Pain, Breast Fibroadenoma
- Trial name
- NCT06026176
- Where
- Nepal
- Volunteers
- 1,023 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Fibrocystic Disease of Breast, Fibrocystic Changes of Breast
Study for Treatment of Moderate or Severe, Periodic, "Cyclic", Breast Pain
History of clinical breast pain for at least the last six months. At least six days of moderate or severe breast pain per cycle. Fibrosis, cysts, nodules involving at least 25% of the surface of one breast.
- Conditions
- Fibrocystic Disease of Breast, Fibrocystic Changes of Breast, Fibrocystic Mastopathy, Pain
- Trial name
- NCT00237523
- Testing
- IoGen (molecular iodine)
- Where
- 39 sites in United States
- Volunteers
- 175 people
- Sponsor
- Symbollon Pharmaceuticals
Mastalgia
Electromyography of the Pectoral Muscle in Mastalgia Patients
Mastalgia is a common problem for women. The aim of this study is to investigate the role of neuromuscular pathologies of the thorax wall at mastalgia ethiopathogenesis.
- Trial name
- NCT02784379
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Breast Cancer
The Effect of Ultrasonography-guided Fascial Plane Blocks in Breast Cancer Surgery Patients
The aim of this study was to evaluate the efficacy of serratus anterior plane (SAP) block, pectoserratus plane (PECS II) block, and erector spinae plane (ESP) block on postoperative acute pain, quality of recovery and chronic…
- Trial name
- NCT06419504
- Testing
- SAP block group, PECS II block group, ESP block group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Antalya Training and Research Hospital
Chronic Pain
Pulsed Radiofrequency for Chronic Mastalgia of Fibrocystic Disease of the Breast
The investigators will evaluate the analgesic efficacy of pulsed radiofrequency on the thoracic paravertebral nerves for patients with chronic mastalgia of fibrocystic disease of the breast
- Trial name
- NCT03888963
- Testing
- PRF
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Assiut University
Mastodynia
Evaluation of Sleep Quality, Nutrition, Anxiety and Depression in Mastalgia
The aim of this study is to investigate the sleep quality, anxiety and depression levels in women with mastalgia using internationally validated scales.
- Trial name
- NCT04690218
- Testing
- Hospital anxiety and depression scale, Pittsburgh Sleep Quality Index, Nutritional Status Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Breast Neoplasms, Survivors
The Effect of Pain Neuroscience Education and Behavioural Graded Activity on Chronic Pain in Breast Cancer Survivors
Chronic pain in breast cancer survivors (BCS) is of considerable concern as it impacts the health-related quality of life (HRQoL) and activities of daily living negatively.
- Conditions
- Breast Neoplasms, Survivors, Chronic Pain
- Trial name
- BCS-PAIN (NCT04531917)
- Testing
- Pain Neuroscience Education, Behavioural Graded Activity, Usual care
- Where
- Belgium
- Volunteers
- 122 people
- Sponsor
- Universitair Ziekenhuis Brussel
Breast Cancer
Effect of Patient Education on Reported Bone Pain in Breast Cancer Patients Receiving Chemotherapy and Pegfilgrastim
The purpose of this study is to determine if patient education can affect patient reported bone pain in breast cancer patients receiving chemotherapy and pegfilgrastim.
- Trial name
- VINE (NCT01752907)
- Testing
- General Education DVD, Bone Pain Education DVD
- Where
- 51 sites in United States
- Volunteers
- 304 people
- Sponsor
- Amgen
Breast Pain, Non-cyclical Mastalgia
Treatment of Breast Pain Using A Medication (Diclofenac) Applied to the Skin
The study was a randomized, double-blinded, crossover trial of topical diclofenac and placebo (10 weeks of each) for the treatment of noncyclic breast pain.
- Conditions
- Breast Pain, Non-cyclical Mastalgia, Surgical Scar-Related Breast Pain
- Trial name
- NCT00276419
- Testing
- Diclofenac
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Mayo Clinic
Gynaecomastia, Prostate Cancer
Casodex - Nolvadex Combination
This study looks at the relationship in the dose of nolvadex and the incidence of gynaecomastia and also Prostate Specific Antigen (PSA) inhibition when co-administered with Casodex.
- Trial name
- NCT00637871
- Testing
- Casodex, Tamoxifen
- Sponsor
- AstraZeneca
Prostate Cancer
Compare the Value of Prophylactic Versus Therapeutic Breast Radiotherapy in CASODEX
The primary objective of this trial is to examine the value of prophylactic versus therapeutic breast radiotherapy in Casodex monotherapy induced gynaecomastia and/or breast pain.
- Trial name
- COMART (NCT00590213)
- Testing
- Casodex 150mg, Radiotherapy, Haematology
- Where
- 9 sites in Turkey (Türkiye)
- Volunteers
- 125 people
- Sponsor
- AstraZeneca
Cyclic Breast Pain, Cyclic Mastalgia
Study of Afimoxifene Gel to Treat Cyclic Mastalgia in Premenopausal Women
The purpose of this study is to evaluate the efficacy of two doses of 4-hydroxy tamoxifen (4-OHT) compared with placebo on the intensity of cyclic mastalgia in pre-menopausal women with regular menstrual cycles who are not taking…
- Trial name
- NCT00272714
- Testing
- Afimoxifene (0.057%) in hydroalcoholic gel
- Volunteers
- 146 people
- Sponsor
- ASCEND Therapeutics
Bone Pain in Stage I - III Breast Cancer
NOLAN: Naproxen or Loratadine and Neulasta
The primary objective of the study is to estimate the difference in bone pain between breast cancer patients receiving chemotherapy and pegfilgrastim and either no prophylactic intervention, prophylactic naproxen, or prophylactic…
- Trial name
- NOLAN (NCT01712009)
- Testing
- Naproxen, Loratadine, Pegfilgrastim
- Where
- 83 sites in United States
- Volunteers
- 600 people
- Sponsor
- Amgen
Breast Pain
L.Fermentum CECT5716 in Treatment of Breast Pain
The main objective of this intervention study is to evaluate the efficacy of Lactobacillus fermentum CECT5716 to reduce the presence in the milk of genera Staphylococcus and Streptococcus as risk factors for mastitis in women…
- Trial name
- NCT02093338
- Testing
- Lactobacillus fermentum CECT5716
- Where
- Spain
- Volunteers
- 127 people
- Sponsor
- Biosearch S.A.
Pain, Breast Cancer
Pilot Functional Imaging Study to Evaluate Mechanisms Underlying Chronic Pain in Breast Cancer Patients
The purpose of this study is to better understand why some women with breast cancer develop chronic pain.
- Trial name
- NCT01639417
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Lynn Henry