Clinical trials: Mastodynia
Breast Neoplasms
The Use of Pentoxifylline and Vitamin E in the Treatment of Chronic Breast Pain
An estimated 20 - 45 % of women treated with breast conserving treatment experience chronic pain in the treated breast. The aetiology of this is poorly understood. Some of these women have signs of chronic radiation mastitis.
- Trial name
- NCT00188669
- Testing
- pentoxifylline, alpha-Tocopherol
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University Health Network, Toronto
Moderate to Severe Cyclic Mastalgia
An Open-Label, MultiCenter Evaluation of the Use of Topically Administered FP1198 in Subjects With Pain Associated With Cyclic Mastalgia
The purpose of this study is to determine the safety of topical FP1198 for the treatment of moderate to severe cyclic breast pain (cyclic mastalgia) and to examine the clinical activity of FP1198.
- Trial name
- NCT01105793
- Testing
- Danazol
- Where
- 4 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- FemmePharma Global Healthcare, Inc.
Breast Pain
Local Anesthetic for Total Mastectomy Surgery
Pain following mastectomy surgery for breast cancer can be significant. Poorly managed pain in the immediate time-period following surgery can potentially lead to long-term (chronic) pain conditions.
- Trial name
- NCT02893384
- Testing
- Local Anesthetic Injection above the serratus anterior
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Breast Cancer, Survivorship
Dance Study for Post-surgical Pain in Breast Cancer Survivors
The purpose of this study is to examine how a 12-week, virtual dance program may improve pain and quality of life in participants with persistent post-surgical pain, or PPSP, following mastectomy or lumpectomy.
- Conditions
- Breast Cancer, Survivorship, Pain, Postoperative
- Trial name
- NCT06758102
- Testing
- Dance Program
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Premenstrual Syndrome, Mastodynia
Efficacy and Safety of 20 mg (2 Tablets of 10mg)VAC BNO 1095 FCT on Cyclic Mastodynia and PMS
The purpose of this study is to proof the efficacy and safety of 20 mg (2 tablets of 10 mg) VAC BNO 1095 film-coated tablets in patients suffering from cyclic mastodynia and PMS (pre menstrual syndrome).
- Trial name
- NCT01870687
- Testing
- 20mg VAC BNO 1095 FCT
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Bionorica SE
Breast Cancer
Addtional Effect of Hyperbaric Oxygen to Programmed Physical Activity on Musckoloskeletal Pain in Breast Cancer Elderly
patienst who survived from breast cancer are prescribed long administraion of aromatase inhbitors.. these inhibitors usually induce musckloskeletal pains.
- Trial name
- NCT07662629
- Testing
- hyperbaric therapy and exercise, exercise
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Breast Pain
Premedication to Reduce Discomfort With Screening Mammography
This study will explore the effect of pre-medication with acetaminophen, ibuprofen, and topical lidocaine gel (Topicaine) on the perception of discomfort and overall satisfaction with the mammography experience.
- Trial name
- NCT00382083
- Testing
- 1000 mg acetaminophen, 800 mg ibuprofen, 1 oz 4% lidocaine gel
- Where
- United States
- Sponsor
- Mountain States Tumor and Medical Research Institute
Mammographic Breast Density
Study of the Effects of Cyclodynon on Reducing the Cumulative Risk of Breast Cancer Development in a Female Aged 40-52
Increased mammographic density of mammary gland tissues and hyperprolactinaemia are regarded as one of the risk factors for the development of breast cancer in women aged 40 to 52 years, which necessitates closer monitoring of…
- Trial name
- BIO-CYCL (NCT04498013)
- Testing
- Cyclodynon, Lifestyl modification
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Dr. Struk Tetiana
Breast Pain, Post-Op Complication
Serratus and Parasternal Infrapectoral Block for Breast Surgery.
Effective pain control is important following breast surgery as it improves quality of recovery, decreases the risk of chronic pain development and reduction of overall health care cost.
- Trial name
- NCT03708302
- Testing
- Unilateral serratus plane block, Unilateral parasternal infrapectoral block
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Western University, Canada
Breast Cancer Survivor
Enhanced Pain Coping in Cancer (EPIC): A Study of Managing Treatment-Related Joint Pain in Breast Cancer Survivors
The researchers are doing this study to compare two different types of group therapy and find out whether they are effective approaches for helping breast cancer survivors manage joint pain caused by aromatase inhibitors (AI).
- Trial name
- NCT06728579
- Testing
- Mindfulness Oriented Recovery Enhancement (MORE), Questionnaires, Supportive Psychotherapy (SG)
- Where
- 9 sites in United States
- Volunteers
- 200 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Mastalgia
Omega-3 Fatty Acids Plus Vitamin E Cosupplementation Versus Vitamin E in Fibrocystic Breast Patient
to identify the effect of omega-3 plus vitamin E cosupplementation on mastalgia in patients with FCC and to compare its effect with that of vitamin E only.
- Trial name
- FCC (NCT04694027)
- Testing
- Omega 3 fatty acid, VitaE
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Breast Fibroadenoma
Analgesic Efficacy of Pulsed Radiofrequency in Non-cyclic Mastalgia
Background: Breast pain, mastalgia or mastodynia, is recognized as an organic benign breast disease. Mastalgia may be bilateral, may be in only one breast or part of one breast, and may radiate to the axilla and down the medial…
- Trial name
- NCT03715413
- Testing
- pulsed radiofrequency of 2nd , 3rd and 4th thoracic dorsal root ganglia., Tamoxifen
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Breast Cancer
Clinical Trial Evaluating the Efficacy and Implementation of an Early Adapted Physical Activity to Prevent and Manage Aromatase Inhibitor-induced Musculoskeletal Pain in Breast Cancer (APIS)
Aromatase inhibitors (AI) are the standard adjuvant hormone therapy for postmenopausal women with hormone-sensitive breast cancer.
- Trial name
- APIS (NCT07295457)
- Testing
- Adapted Physical Activity started early, Adapted Physical Activity begins at the start of hormone therapy
- Where
- 2 sites in France
- Volunteers
- 182 people
- Sponsor
- Hospices Civils de Lyon
Breast Cancer, Chemotherapy-Induced Neutropenia
Correlation Between ANC and Bone Pain in Breast Cancer Patients Receiving Long-Acting G-CSF
This prospective, multicenter, non-randomized controlled study aims to evaluate bone pain associated with prophylactic use of long-acting granulocyte colony-stimulating factors (G-CSFs) in patients with breast cancer receiving…
- Conditions
- Breast Cancer, Chemotherapy-Induced Neutropenia, Febrile Neutropenia, Bone Pain
- Trial name
- Bone Pain (NCT07806084)
- Volunteers
- 132 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Mastalgia
Mastalgia Treatment: Is There a Role for Osteopathic Manipulative Treatment
There are many current medical treatments for mastalgia, but few have been proven effective. Our objective is to evaluate the effectiveness of osteopathic manipulative treatment as compared to a light touch protocol and standard…
- Trial name
- NCT01643837
- Testing
- Osteopathic Manipulative Treatment, Osteopathic Manipulative Light Touch Protocol (LT)
- Where
- 2 sites in United States
- Sponsor
- New York Institute of Technology
Neurotoxicity, Pain
D-cycloserine in the Management of Chemotherapy-Induced Peripheral Neuropathic Pain
D-cycloserine may help lessen pain and other symptoms of peripheral neuropathy caused by chemotherapy. It is not yet known whether D-cycloserine is more effective than a placebo in treating peripheral neuropathy caused by…
- Conditions
- Neurotoxicity, Pain, Breast Cancer
- Trial name
- NCT00301080
- Testing
- D-cycloserine
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- Northwestern University
Postoperative Pain Breast Reduction, Mammaplasty
SPSIP Block for Pain Control After Breast Reduction Surgery
The goal of this clinical trial is to learn whether an ultrasound-guided serratus posterior superior intercostal plane block (SPSIP block) can lower the need for opioid pain medicine after breast reduction surgery.
- Conditions
- Postoperative Pain Breast Reduction, Mammaplasty, Analgesia, Nerve Block
- Trial name
- SPSIP-RM (NCT07657949)
- Testing
- Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block, Standard Perioperative Pain Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cumhuriyet University Hospital
Cyclical Breast Pain
Randomized Clinical Trial of Vitamin E and Evening Oil of Primrose for the Managment of Breast Pain
This study is being done to find out what effects Vitamin E or Evening Oil of Primrose has on cyclical breast pain.
- Trial name
- NCT00275600
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Postoperative Pain, Chronic Post Operative Pain
Comparative Analysis of Three Locoregional Anesthesia Methods in Breast Tumour Pathology Surgery
The present study compares the Erector Spinae Plane (ESP) block, Pectoral (PECS II) block, and Serratus-Intercostal Fascial Plane (SIFP) block.
- Conditions
- Postoperative Pain, Chronic Post Operative Pain, Breast Tumor, Locoregional Anesthesia
- Trial name
- NCT05185752
- Testing
- SIFP Block Locoregional Interfascial Anesthesic Technique, PECS II block: Locoregional Interfascial Anesthesic Technique, ESP block: Locoregional Interfascial Anesthesic Technique
- Where
- Spain
- Volunteers
- 103 people
- Sponsor
- University of Valencia
Acupuncture, Mastodynia
Acupuncture for Breast Pain
This study is conducted to assess the efficacy and safety of acupuncture in moderate to severe cyclic breast pain.
- Trial name
- NCT05548374
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences