Clinical trials: Maternal; Procedure
Maternal Distress, Perinatal Depression
A Common Elements-based Intervention to Improve Maternal Psychological Well-being and Mother-infant Interaction
Background: Millions of children in low resource settings are at high risk of poor development due to factors such as undernutrition, inadequate stimulation and maternal depression.
- Conditions
- Maternal Distress, Perinatal Depression, Development Delay, Language Delay
- Trial name
- NCT04252807
- Testing
- Intervention arm, Treatment as Usual
- Where
- Pakistan
- Volunteers
- 250 people
- Sponsor
- Human Development Research Foundation, Pakistan
Exercise, Women
Conmigo: A Mother-daughter Intervention to Promote Physical Activity
Regular physical activity (PA) contributes to reduced risk of obesity, chronic disease, cardiovascular disease, and cancer, and can improve emotional and mental health, learning, productivity, and social skills.
- Conditions
- Exercise, Women, Hispanic Americans, Child
- Trial name
- Conmigo (NCT04736030)
- Testing
- Intervention
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Dietary Habits, Health Knowledge, Attitudes, Practices
Evaluation Nutrition Education Intervention on Pulse and Cereal Mix for Complementary Food in Southern Ethiopia
The overall purpose of the study is to evaluate nutrition education interventions to promote pulse incorporated complementary food to the wider rural community through the government system to improve maternal knowledge, attitude…
- Conditions
- Dietary Habits, Health Knowledge, Attitudes, Practices, Wasting
- Trial name
- NCT02638571
- Testing
- enhanced education on pulse use in complementary foods
- Volunteers
- 772 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Pregnancy-Related Condition, Unspecified, Overweight or Obesity
Supporting Lifestyle Change in Obese Pregnant Mothers Through Wearable Internet-of-Things (SLIM)
Maternal obesity increases risks for the mother and her child. It is crucial to arouse the pregnant and postpartum women´s willingness of change and motivation to take care of their own and their unborn child´s health.
- Trial name
- SLIM (NCT04826861)
- Testing
- SLIM intervention
- Where
- Finland
- Volunteers
- 55 people
- Sponsor
- University of Turku
Substance Use Treatment, Perinatal Substance Use
Improving Outcomes for Early Postpartum Mothers in Outpatient MOUD Treatment
Drug overdose is a leading cause of death among postpartum women and opioid-related mortality is 4 times higher in the postpartum period when compared to the third trimester of pregnancy.
- Conditions
- Substance Use Treatment, Perinatal Substance Use, Parenting
- Trial name
- NCT07071766
- Testing
- Proud of Baby and Me
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Arkansas
Obesity, Weight Gain
Diet, Physical Activity and Breastfeeding Intervention on Maternal Nutrition, Offspring Growth and Development
NCDs are observed mostly in adults, however there is strong evidence that suggests NCDs origin early in life, thus the first 1000 days of life (conception to age 2yrs).
- Conditions
- Obesity, Weight Gain, Metabolic Diseases, Birth Weight
- Trial name
- NCT01916603
- Testing
- Normative Intervention
- Where
- Chile
- Volunteers
- 2,400 people
- Sponsor
- University of Chile
Postpartum Depression, Postpartum Anxiety
Mother-infant Bonding in the Brain: a Mindfulness-based Intervention
The study investigates the effectiveness of the mindfulness-based intervention "Mindful with your Baby" in women with babies between 5-9 months postpartum who experience heightened levels of postpartum depression, anxiety and/or…
- Conditions
- Postpartum Depression, Postpartum Anxiety, Parental Stress
- Trial name
- NCT05830266
- Testing
- "Mindful with your Baby" group-based therapist-guided intervention, "Mindful with your baby" self-guided online intervention
- Where
- Netherlands
- Volunteers
- 64 people
- Sponsor
- Tilburg University
Improving Young Child Nutrition
Integrated Education Intervention to Improve Infant and Young Child Nutrition and Growth in Ghana
In Ghana the level of malnutrition is high among children below five years of age, particularly in rural areas. The objective of the study was to investigate the effects of an education intervention aimed at addressing poor…
- Trial name
- NCT01612442
- Testing
- nutrition and agricultural education, nutrition education
- Where
- Ghana
- Volunteers
- 367 people, healthy volunteers welcome
- Sponsor
- McGill University
Mother-Infant Bonding
Mandala Intervention on Mother-Infant Bonding and Parenting Self-Efficacy After Negative Birth Experiences
The purpose of this randomized controlled trial is to evaluate the impact of a mandala-based art intervention on mother-infant bonding and parenting self-efficacy among primiparous women (first-time mothers) who have had a…
- Trial name
- NCT07461922
- Testing
- Mandala Coloring, Free Coloring
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Vasa Previa, Pregnancy Complications
Fetoscopic Laser Photocoagulation in Management of Vasa Previa
In this research study, the investigators want to learn more about the safety and effectiveness of a fetal surgery, known as fetoscopic laser photocoagulation (FLP), for the treatment of a pregnancy condition called vasa previa…
- Conditions
- Vasa Previa, Pregnancy Complications, Maternal; Procedure, In Utero Procedure Affecting Fetus or Newborn
- Trial name
- FLUMEN (NCT06290232)
- Testing
- Fetoscopic Laser Photocoagulation
- Where
- United States
- Sponsor
- Boston Children's Hospital
Gestational Diabetes Mellitus (GDM)
SFEE Diet Management for Gestational Diabetes Mellitus
This study aims to evaluate the impact of the Self-Family-Environment Empowerment (SFEE) diet management intervention on glycemic control, maternal outcomes, and dietary adherence in pregnant women with gestational diabetes…
- Trial name
- SFEE (NCT06707064)
- Testing
- SFEE Diet Management Intervention, Standard Dietary Advice
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Ji Jing
Breast Cancer
Enhancing Connections: Helping the Mother With Breast Cancer Support Her Child
This is a 6-state randomized controlled trial (RCT) that uses a behavioral intervention to enhance parenting skills for school age children when a mother is recently diagnosed with early stage breast cancer.
- Trial name
- EC R01 (NCT00194571)
- Testing
- Educational counseling intervention
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- University of Washington
Post-traumatic Stress Disorder, Dissociation
An Intervention to Enhance Well-Being in Trauma Exposed New Mothers
This pilot randomized controlled trial will evaluate the feasibility and effectiveness of a mobile neurofeedback intervention for increasing maternal overall well-being, and measuring whether mothers experience any subsequent…
- Conditions
- Post-traumatic Stress Disorder, Dissociation, Maternal Care Patterns, Infant Behavior
- Trial name
- NCT05474534
- Testing
- Neurofeedback (MUSE 2)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Wayne State University
Parent Child Relationship, Child Social-Emotional Development
The Impact of an Evidence-Based Parenting Service on Maternal Sensitivity and Infant Cellular Aging in a Population of Under-Resourced Families
The goal of this clinical trial study is to learn how stress in childhood, or Early Life Adversity (ELA), gets "under the skin" and influences long-term health.
- Conditions
- Parent Child Relationship, Child Social-Emotional Development, Telomere Length, Epigenetic Aging
- Trial name
- NCT06740266
- Testing
- Promoting First Relationships in Primary Care (PFR-PC)
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Washington
Fetal Growth Restriction (FGR)
Melatonin and Perinatal Outcomes in MVM-Related Fetal Growth Restriction (MIMVMFGR)
The goal of this clinical trial is to evaluate the efficacy and safety of melatonin in the treatment of early-onset severe maternal vascular malperfusion-related fetal growth restriction (MVM-FGR), and to determine its effects on…
- Trial name
- MIMVMFGR (NCT07549295)
- Testing
- Melatonin
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Opaque Bottles, Conventional, Clear Bottles
Opaque Bottle Study
The proposed research aimed to conduct an intervention study assessing the effect of feeding mode (clear versus opaque bottle) on the quality and outcome of infant feeding interactions.
- Trial name
- NCT03711370
- Testing
- Clear Bottle, Opaque Bottle
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Language Development, Language Delay
A Language Intervention Study of Preterm Infants
This is a randomized controlled trial to study a reading intervention in the NICU among preterm infants using LENA (Language Environment Analysis) recordings, linguistic feedback, and a language curriculum to improve the neonatal…
- Conditions
- Language Development, Language Delay, Mother-Infant Interaction, Maternal Behavior
- Trial name
- NCT03688386
- Testing
- Reading intervention, Infant bonding, LENA recording
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Newborn, Pain
The Effectiveness of Two Different Methods Applied During Heel Blood Collection on Pain Level of Healthy Term Newborns
This study was planned to evaluate the effect of two different non-pharmacologic pain relief methods (swaddling and maternal holding) on healthy term newborn's pain levels during heel stick. Study hypotheses are; Hypothesis 1.
- Conditions
- Newborn, Pain, Maternal; Procedure, Needle Stick
- Trial name
- NCT04625010
- Testing
- Swaddling, Maternal holding
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Pregnancy, Anesthesia
Continuous Noninvasive Method for Estimating and Predicting Maternal and Fetal Hemodynamic Changes During Regional Anesthesia
Machine learning techniques and algorithms originally developed for use in the field of robotics can be applied to continuous, noninvasive physiological waveform data to discover hidden, hemodynamic relationships.
- Trial name
- NCT01699243
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- University of Colorado, Denver
Obesity, Childhood, Asthma in Children
Asthma and Obesity Diet Versus Exercise
Obesity is recognized as a pro-inflammatory condition associated with multiple chronic diseases, including asthma. The specific mechanisms linking asthma and obesity remain hypothetical.
- Conditions
- Obesity, Childhood, Asthma in Children, Inflammatory Response, Metabolic Syndrome
- Trial name
- NCT03644355
- Testing
- Lifestyle counseling
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans