Clinical trials: Maternal Deaths
Stillbirth and Fetal Death, Perinatal Death
Mothers Working to Prevent Early Stillbirth Study 20-28
This project aims to identify factors linked to pregnancy losses occurring between 20 and 28 weeks of pregnancy that can be modified by changing mother's behaviour or healthcare provision.
- Trial name
- MiNESS20-28 (NCT06005272)
- Testing
- Questionnaire
- Where
- United Kingdom
- Volunteers
- 948 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Maternal Mortality, Access to Health Care
Project to Use Community Health Workers to Reduce Maternal Deaths
The purpose of this trial is to establish if several interventions will help women in rural Tanzania access health care services during pregnancy and at the time of delivery.
- Trial name
- EWH (NCT03024905)
- Testing
- Village meeting and travel vouchers, Birth kit with misoprostol
- Where
- Tanzania
- Volunteers
- 17,000 people, healthy volunteers welcome
- Sponsor
- Bruyère Health Research Institute.
Maternal Death During Childbirth, Pregnancy Complications
Wireless Physiologic Monitoring in Postpartum Women
To estimate the clinical effectiveness of wireless physiologic monitoring of women in the first 24 hours after cesarean delivery at Mbarara Regional Referral Hospital
- Trial name
- WIMS (NCT04060667)
- Testing
- Wireless physiologic monitoring
- Where
- Uganda
- Volunteers
- 3,191 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Preeclampsia
Prevention of Maternal and Perinatal Complications by Enoxaparin in Women With Previous Severe Preeclampsia
Preeclampsia (PE) complicates 2-8% of pregnancies. It is associated with an increased risk of adverse maternal (death, eclampsia, abruptio placenta, HELLP syndrome) and perinatal (perinatal death, growth restriction, prematurity)…
- Trial name
- HEPEPE (NCT00986765)
- Testing
- Lovenox® (enoxaparin), Aspegic ® (Aspirin)
- Where
- France
- Volunteers
- 257 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Prevention of Sudden Death
Training Mothers of Infants in Infant Cardiopulmonary Resuscitation (CPR)
This research will be a prospective, cohort study to determine if mothers of infants/newborns are more willing to complete CPR training using a 22-minute instructional DVD and infant manikin versus traditional four hour didactic…
- Trial name
- NCT00570869
- Testing
- CPR Anytime
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Lehigh Valley Hospital
Maternal Mortality
Effectiveness of the Education Program on Increasing the Competency Level of Health Cadres in Indonesia
Ending preventable maternal mortality (EPMM): By 2030, every country should reduce its maternal mortality ratio (MMR) by at least two-thirds from the 2010 baseline.
- Trial name
- NCT06134518
- Testing
- The education program, the initial orientation from the PHCs
- Where
- Indonesia
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Hiroshima University
Hypertension, Morality
Mortality Outcome of Controlled Hypertension
This review focuses on the assumption of mortality outcome of participants remaining label hypertension care is adequately managed when pressure targets are met with both qualitative and quantitaive method.
- Conditions
- Hypertension, Morality, Death, Pre-Eclampsia
- Trial name
- MOCH1 (NCT07187596)
- Where
- Thailand
- Volunteers
- 2,547 people
- Sponsor
- DejthidaNathaphong
Obstetric Labor Complications, Stillbirth
The PartoMa Project: For Improving Monitoring, Action and Triage During Labour
OVERALL OBJECTIVE In an East African referral hospital, to develop and analyze the effect of locally agreed and achievable guidelines and a continual in-house training program for strengthening partogram-based…
- Conditions
- Obstetric Labor Complications, Stillbirth, Maternal Death
- Trial name
- PartoMa (NCT02318420)
- Testing
- The PartoMa intervention
- Where
- Tanzania
- Volunteers
- 3,087 people
- Sponsor
- Ib Christian Bygbjerg
Anemia, Low Birth Weight
Dietary Diversity is Associated With Maternal Anemia and Key Prenatal Outcomes in Ethiopia
Background: Maternal and child under-nutrition is the underlying cause of death for millions across the globe. Anemia during pregnancy is among the leading nutritional disorders with serious short and long term consequences to…
- Conditions
- Anemia, Low Birth Weight, Pre-Term Birth, Still Birth
- Trial name
- NCT02620943
- Where
- Ethiopia
- Volunteers
- 374 people
- Sponsor
- Dilla University
Pre-Eclampsia, Hypertension, Pregnancy-Induced
Low Dose Calcium to Prevent Preeclampsia
The purpose of this study is to assess, in pregnant women with calcium-poor diets, what is the effectiveness of low-dose (500 mg/day) calcium supplements associated with an educational intervention, compared to the educational…
- Conditions
- Pre-Eclampsia, Hypertension, Pregnancy-Induced, Dietary Calcium Deficiency
- Trial name
- AMCAL (NCT02338687)
- Testing
- calcium, Educational sessions
- Where
- Brazil
- Volunteers
- 1,040 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Circulating Cell Free Fetal DNA, Intrauterine Fetal Demise
The Use of Cell Free Fetal DNA in the Maternal Blood in the Evaluation of Intrauterine Fetal Demise and Miscarriage
Women presenting to Washington Hospital Center with fetal loss would be offered participation in the study. The objective is to determine if ccffDNA obtained from maternal blood is present in the setting of missed abortion or…
- Conditions
- Circulating Cell Free Fetal DNA, Intrauterine Fetal Demise, Miscarriage
- Trial name
- NCT01916928
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Maternal Death, Cardiac Arrest
Assessing a New Proforma for Maternal Cardiac Arrest
During the Multidisciplinary Obstetric and Midwifery Simulation (MOMS) course, groups of delegates manage simulated clinical emergencies, whilst the remaining delegates observe the scenario via a video link.
- Conditions
- Maternal Death, Cardiac Arrest, Heart Arrest
- Trial name
- NCT04260386
- Testing
- Non-Interventional
- Where
- United Kingdom
- Volunteers
- 39 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Pregnancy, Pregnancy Complications
AI-POCUS for Maternal and Neonatal Health in Ethiopia
Maternal and neonatal health remains one of the most pressing global health challenges, particularly in low- and middle-income countries (LMICs).
- Conditions
- Pregnancy, Pregnancy Complications, Preterm Birth, Fetal Growth Restriction
- Trial name
- AIM-ETH (NCT07171086)
- Testing
- AI-POCUS (BabyChecker, Delft Imaging), AI-POCUS (Edan, China)
- Where
- Ethiopia
- Volunteers
- 1,059 people, healthy volunteers welcome
- Sponsor
- Tsinghua University
Postpartum Infection
Trends in Pregnancy Outcomes Beyond Twenty Weeks Gestational Age in Assisted Reproductive Technology Conceived Pregnancies in British Columbia
Examining outcomes beyond 20 weeks gestational age in pregnancies conceived by ART compared to spontaneously conceived pregnancies 1.
- Trial name
- NCT06726603
- Testing
- Assisted Reproductive Technology
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Preeclampsia, Intrauterine Growth Restriction
sFlt1/PlGF and Planned Delivery to Prevent Preeclampsia at Term.
Preeclampsia (PE) affects ~5% of pregnancies. Although improved obstetrical care has significantly diminished associated maternal mortality, PE remains a leading cause of maternal morbidity and mortality in the world.
- Conditions
- Preeclampsia, Intrauterine Growth Restriction, Maternal Hypertension, Neonatal Outcome
- Trial name
- PE37 (NCT04766866)
- Testing
- sFlt1/PlGF screening in maternal blood at 35 to 36.6 weeks of gestation
- Where
- 21 sites in Belgium, Colombia and 7 more
- Volunteers
- 9,132 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Sudden Infant Death
The Effect of Video-Assisted Sudden Infant Death Syndrome Prevention Training Program and Counseling Practice on Mothers' Knowledge Level and Self-efficacy: Randomized Controlled Study
Sudden Infant Death Syndrome (SIDS) is one of the leading causes of infant mortality in the postneonatal period, but it can be prevented and its incidence can be reduced by creating a safe sleep environment with modifiable risk…
- Trial name
- NCT05823051
- Testing
- VASIDS-TP and Counseling Practice
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Dilara Aydin Tozlu
Maternal Death, Maternal Infections Affecting Fetus or Newborn
Azithromycin-Prevention in Labor Use Study (A-PLUS)
Maternal and neonatal infections are among the most frequent causes of maternal and neonatal deaths, and current antibiotic strategies have not been effective in preventing many of these deaths.
- Conditions
- Maternal Death, Maternal Infections Affecting Fetus or Newborn, Neonatal SEPSIS, Maternal Sepsis During Labor
- Trial name
- NCT03871491
- Testing
- Azithromycin
- Where
- 8 sites in Bangladesh, Democratic Republic of the Congo and 5 more
- Volunteers
- 58,747 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Neonatal Hypoxia and Asphyxia
Can Shorter Time Intervals Help the Baby Survive the Triad Effect of Maternal Hypertension, Caesarean Section and Spinal Anesthesia?
Patients were classified into two equal groups using the presence or absence of hypertension during pregnancy into: hypertensive group (BP>140/90) and normotensive group (BP≤140/90.
- Trial name
- NCT03461913
- Testing
- Cesarean section
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Suspected Damage to Fetus From Other Disease in the Mother, Affecting Management of Mother, With Delivery, Patient Death or Serious Disability Associated With A Haemolytic Reaction Due to the Administration of ABO-Incompatible Blood or Blood Products
The Use of Lung Ultrasonography in the Delivery Room in Neonates
Lung ultrasonography has become frequently used in neonatal intensive care units because it is a diagnostic, useful, harmless, radiation-free, bedside, reproducible and practical method.
- Trial name
- LUSIN (NCT06314789)
- Testing
- doing lung ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University