Clinical trials: Maternal Health Disparities
Pregnancy, Postpartum Depression
Rosie the Chatbot: Leveraging Automated and Personalized Health Information Communication
Rosie the Chatbot is an educational chatbot that moms can have on their computers or cellphones and will work by moms typing in their questions about pregnancy, health, infant milestones, and other variety of health related…
- Conditions
- Pregnancy, Postpartum Depression, Infant Development, Infant Conditions
- Trial name
- NCT06053515
- Testing
- Rosie the Chatbot
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Emergency Maternity Care, Health Inequalities in Maternity Care Access
Disparities In Access to the Northwest Ambulance Service During Pregnancy, Birth and Postpartum Period and Its Association With Neonatal and Maternal Outcomes
This study is the first in the United Kingdom (UK) to look at how women and families from different backgrounds use ambulance services during the 'perinatal period' - through pregnancy, birth, and shortly after having a baby.
- Conditions
- Emergency Maternity Care, Health Inequalities in Maternity Care Access, Disparities in Access to Maternity Care, Deprivation
- Trial name
- DIAAS (NCT07049263)
- Where
- United Kingdom
- Volunteers
- 18,000 people
- Sponsor
- Manchester University NHS Foundation Trust
Pregnancy, Maternal Anemia
Better Birth Outcomes Through Technology, Education, and Reporting
This is a pragmatic randomized control trial to evaluate the BETTER intervention compared to standard obstetrical care (control) to determine whether it helps to reduce maternal anemia and other adverse pregnancy outcomes.
- Conditions
- Pregnancy, Maternal Anemia, Pre-Term Birth, Hypertensive Disorders
- Trial name
- BETTER (NCT06261398)
- Testing
- BETTER: motivational interviewing and text messaging, Standard of care
- Where
- 3 sites in United States
- Volunteers
- 550 people
- Sponsor
- Ohio State University
Pregnancy Related, Maternal Health
Accountability for Care Through Undoing Racism & Equity for Moms
This project-also known as "Accountability for Care through Undoing Racism \& Equity for Moms" or ACURE4Moms-aims to reduce Black-White maternal health disparities using multi-level interventions designed to decrease bias in…
- Conditions
- Pregnancy Related, Maternal Health, Maternal Mortality, Low Birthweight
- Trial name
- ACURE4Moms (NCT05484804)
- Testing
- Data Accountability and Transparency, Community-Based Doula (CBD) Support
- Where
- United States
- Volunteers
- 60,000 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Maternal Morbidity and Mortality, Health Disparities
The Maternal Health Multilevel Intervention for Racial Equity (MIRACLE) Project
This community-partnered study will scale a community, provider, and system-level implementation intervention to reduce African American maternal morbidity and mortality disparities in two Michigan counties (Genesee and Kent).
- Trial name
- MIRACLE (NCT05386316)
- Testing
- Multilevel intervention for racial disparities in severe maternal morbidity and mortality, Standard Enhanced Prenatal Care (EPC) services
- Where
- United States
- Volunteers
- 540,000 people
- Sponsor
- Michigan State University
Breastfeeding, Breastfeeding Support
Peer-Support Breastfeeding Program for Mothers in Severe Socioeconomic Deprivation: Feasibility Study
Breastfeeding provides well-established and "irreplaceable" health benefits for both mothers and infants. However, breastfeeding rates in France remain among the lowest in Europe and are strongly associated with socioeconomic…
- Conditions
- Breastfeeding, Breastfeeding Support, Health Disparities, Health Inequalities
- Trial name
- PARTAGE (NCT07499466)
- Testing
- Peer-Support Breastfeeding Intervention
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Kōmmour Prenatal Among Marshallese Pregnant Women
Exploring the Feasibility of Kōmmour Prenatal to Reduce Maternal and Infant Health Disparities
The purpose of the study is to culturally adapt and examine the feasibility of a group prenatal program (Kōmmour Prenatal) to reduce maternal and infant health disparities among Marshallese Pacific Islander women in the US.
- Trial name
- NCT04558619
- Testing
- Kōmmour Prenatal
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Tobacco Use, Tobacco Use Cessation
Integrating CHWs Into Prenatal Care for Maternal Smoking Cessation
This develops a novel behavioral tobacco cessation program for pregnant smokers in San Bernardino County.
- Conditions
- Tobacco Use, Tobacco Use Cessation, Tobacco Use in Childbirth
- Trial name
- SFHOPE (NCT06438549)
- Testing
- HCP-CHW Integration into Prenatal Care for Smoking Cessation, Control Arm
- Where
- 2 sites in United States
- Volunteers
- 105 people
- Sponsor
- Loma Linda University
Pregnancy, Post Partum
Deconstructing Maternal Burdens: Doulas and the Community Unite for Health
This study is a randomized controlled trial comparing two models of doula support for pregnant individuals enrolled in Medicaid: an enhanced doula support model, in which support starts earlier in pregnancy, occurs more…
- Conditions
- Pregnancy, Post Partum, Doula Care, Postpartum Depression (PPD)
- Trial name
- UNITE (NCT07799805)
- Testing
- Doula, Standard (non-enhanced) Medicaid doula support
- Where
- United States
- Volunteers
- 516 people
- Sponsor
- University of Florida
Breastfeeding
Breast for Success: A Family-Centered Intervention in Support of Breastfeeding Among High-risk Low-income Mothers
Breast for Success is a new direct service program focused on overcoming barriers to breastfeeding for low-income inner-city mothers by use of a culturally competent and home-based educational and support intervention.
- Trial name
- BFS (NCT01272661)
- Testing
- Enhanced Curriculum, Enhanced Curriculum+Breastfeeding Doula, Enhanced Curriculum +Father Support
- Where
- United States
- Volunteers
- 1,296 people
- Sponsor
- University Hospitals Cleveland Medical Center
Infant Mortality, Infant Death
Today Not Tomorrow Pregnancy and Infant Support Program (TNT- PISP)
This pilot project aims to implement and investigate the feasibility and acceptability of a unique community based prenatal care and support model for African American women and infants in Dane County.
- Conditions
- Infant Mortality, Infant Death, Racial Bias, Prenatal Stress
- Trial name
- NCT04100577
- Testing
- Today Not Tomorrrow Pregnancy and Infant Support Program
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Perinatal Depression
Dialectical Behavior Therapy for Pregnant Women
The cumulative effects of adverse childhood experiences (ACEs) can lead to prolonged activation of stress response systems, known as toxic stress.
- Trial name
- NCT03938350
- Testing
- Dialectical Behavior Therapy (DBT) Skills Training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Emory University
Physical Activity, Sedentary Behavior
Teen Mom Study Feasibility Trial
The proposed multicomponent digital health intervention has the potential to significantly impact the trajectory of maternal health in a rural, pregnant, Black adolescent population with the highest risks for cardiometabolic…
- Conditions
- Physical Activity, Sedentary Behavior, Gestational Weight Gain, Social Determinants of Health
- Trial name
- NCT05843903
- Testing
- #BabyLetsMove
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Postpartum Depression (PPD), Cardiac Event
Living Healthy for Moms RCT
LHMoms is a novel integrated care intervention that focuses intensively on care continuity and community-to-healthcare linkages for postpartum birthing individuals.
- Trial name
- LHMoms (NCT06666400)
- Testing
- LHMoms Intervention, No intervention
- Where
- 4 sites in United States
- Volunteers
- 21 people
- Sponsor
- Columbia University
Obesity, Obesity, Childhood
In-home Obesity Prevention to Reach Low-income Infants
Existing obesity prevention efforts have had limited success among underserved, low-income children. This study capitalizes on the strengths of a nationwide ongoing Home Visitation Program (HVP), which serves at-risk, low-income…
- Conditions
- Obesity, Obesity, Childhood, Obesity; Familial
- Trial name
- NCT03529695
- Testing
- Standard HVP Curriculum, Obesity Prevention
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Mental Health, Child Wellbeing
Generation Victoria Cohort 2020s: A Statewide Longitudinal Cohort Study of Victorian Children and Their Parents
Generation Victoria (GenV) is a longitudinal, population-based study of Victorian children and their parents that will bring together data on a wide range of conditions ,exposures and outcomes.
- Conditions
- Mental Health, Child Wellbeing, Infant Health, Child Health
- Trial name
- GenV (NCT05394363)
- Where
- Australia
- Volunteers
- 150,000 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Premature Birth, Low Birth Weight
Pilot Trial of CenteringPregnancy With Mindfulness Skills
In the U.S., rates of preterm birth and low birth weight have increased over the past 30 years. Poor birth outcomes are especially high among racial/ethnic minority populations.
- Conditions
- Premature Birth, Low Birth Weight, Postpartum Depression
- Trial name
- NCT01646463
- Testing
- CenteringPregnancy, CenteringPregnancy with Mindfulness Skills
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pregnancy Related, Postpartum Sadness
Fourth Trimester - A Web-based Tool for Postpartum Care to Address the Needs of Underserved Women
The postpartum period is a critical time for both maternal and child health, and more than half of all maternal deaths occur postpartum, from one day to one year after birth.
- Trial name
- NCT04475718
- Testing
- Fourth Trimester Mobile Tool
- Where
- 2 sites in United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Carelon Research
Maternal Mortality Disparities, Maternal Morbidity Disparities
Scaling up Maternal Health Equity Best Practices
This study works with prenatal and postnatal care providers in 12 Michigan counties to scale up best practices for maternal health equity.
- Trial name
- NCT06541951
- Testing
- Services as usual, Scale-up implementation approach
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Substance-Related Disorders
Growing Together: Women in Opioid Treatment and Their Infants
This study evaluates the effectiveness of the home-based therapeutic parenting intervention BRIGHT with pregnant women and postpartum mothers with opioid use disorders (OUDs) and their infants.
- Trial name
- NCT03866694
- Testing
- BRIGHT, STAR/TAU+
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Boston University Charles River Campus