Clinical trials: Maternal Outcome
Pre-Eclampsia
Maternal and Neonatal Outcome in Severe Preeclampsia
In normal pregnancy the spiral arteries in the placental bed are invaded by trophoblast, which becomes incorporated into the vessel wall and replaces the endothelium, muscular layer and neural tissue
- Trial name
- NCT04126122
- Testing
- Ultrasonography to assess fetus and mother
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Obesity, Maternal, Weight Gain, Maternal
The Difference of Weight Gain Tendencies and Obesity During Pregnancy
Background: Excess weight and obesity are a global pandemic, particularly among women of childbearing age. Pre-pregnancy obesity is linked to adverse maternal and neonatal outcomes, including preterm birth, macrosomia…
- Conditions
- Obesity, Maternal, Weight Gain, Maternal, Birth Weight, Birth Outcome, Adverse
- Trial name
- NCT06540014
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Maternal Care Patterns, Nutrition, Healthy
The 1000 First Day of Life : Effect of Multi Micronutrients Supplementation on Pregnancy Outcomes
To monitor the effects of multi micronutrients supplementations during pregnancy towards pregnancy outcomes
- Conditions
- Maternal Care Patterns, Nutrition, Healthy, Nutritional Deficiency, Maternal-Fetal Relations
- Trial name
- NCT06035315
- Testing
- Multiple Micronutrients during pregnancy
- Where
- 2 sites in Indonesia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Environmental Exposure, Pregnancy Outcome
The Ma'Anshan Birth Cohort (MABC)
The Ma'anshan Birth Cohort (MABC) is a population-based prospective pregnancy and birth cohort study that aims to explore the early environmental and genetic determinants of maternal and child health, with a focus on health…
- Conditions
- Environmental Exposure, Pregnancy Outcome, Birth Defects, Child Development
- Trial name
- NCT03215368
- Where
- China
- Volunteers
- 3,474 people, healthy volunteers welcome
- Sponsor
- Anhui Medical University
Metformin for Obese Pregnant Women
Maternal and Fetal Outcome With Metformin Therapy for Obese Pregnant Women .
To evaluate the role of metformin in pregnant women with obesity (BMI above 30) , on maternal and infant outcome.
- Trial name
- NCT05554679
- Testing
- Metformin
- Where
- Egypt
- Volunteers
- 178 people
- Sponsor
- Assiut University
Parturition Complication
Impact of Traumatic Childbirth on Mother-baby Dyadic Interaction and Maternal Psychological Outcome: a Prospective Study
While a significant percentage of women in France have difficult pregnancies and negative childbirth experiences, there is still lack of documentation on the impact of these traumatic experiences on maternal health and…
- Trial name
- TOPASE+ (NCT06587373)
- Testing
- Assessment of the quality of mother-child dyadic relationships
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Effect of Insomnia and Sleep Deprivation in 3rdtrimester
Effect of Clinical Insomnia and Sleep Deprivation on Maternal-fetal Outcome Among Egyptian Females in 3rd Trimester
This prospective observational study aims at investigating whether insomnia or sleep deprivation during the 3rd trimester of pregnancy can be implicated in the occurrence of adverse maternal or fetal outcome.
- Trial name
- NCT04612361
- Testing
- insommnia severity index questionnaire
- Where
- Egypt
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Dr. Osman Hospital
Abruptio Placentae; Affecting Fetus or Newborn
Normotensive and Hypertensive Placental Abruptions
Placental abruption is a significant cause of both maternal morbidity and neonatal morbidity and mortality. Most abruptions accept to be related to a chronic placental disease process.
- Trial name
- NCT04449601
- Testing
- clinical assesment
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Hatice Akkaya
Pregnancy
DHA Supplementation and Pregnancy Outcome
Supplementation with DHA during pregnancy will increase gestational length and improve cognitive development.
- Trial name
- NCT02219399
- Testing
- 600 mg DHA, 300 mg DHA
- Where
- 2 sites in United States
- Volunteers
- 871 people
- Sponsor
- Colorado State University
Maternal Behavior, Mobile Health
A Prospective Randomized Controlled Trial of Mobile Medical Used for Management of Pregnant Women
A multicenter, randomized controlled trial was conducted to investigate whether health education and life style management through WeChat group chat was: 1. more effective in improving pregnancy outcomes in normal pregnant women.
- Conditions
- Maternal Behavior, Mobile Health, Pregnancy Outcome, GDM
- Trial name
- NCT03748576
- Testing
- telemedicine: management through WeChat group chat
- Where
- China
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Hypertension Induced by Pregnancy, Pre-Eclampsia
Placental Growth and Adverse Pregnancy Outcomes
The purpose of this study to determine if measurement of maternal serum biomarkers and evaluation of the placenta by ultrasound can improve prediction of adverse pregnancy outcomes.
- Conditions
- Hypertension Induced by Pregnancy, Pre-Eclampsia, IUGR
- Trial name
- NCT01669525
- Where
- United States
- Volunteers
- 1,043 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Termination of Pregnancy
Obstetric & Pediatric Evolution Following Parental Refusal for Early Termination of Pregnancy Despite Fetal Risk
More and more parents decide to maintain pregnancy which could have been interrupted because of serious fetal pathologies. In this observational study, the investigators examine obstetrical and pediatric evolution of these…
- Trial name
- NCT03393455
- Testing
- not accurate
- Where
- France
- Volunteers
- 211 people
- Sponsor
- University Hospital, Montpellier
Premature Rupture of Membrane
Fetal and Maternal Outcome in Preterm Premature Rupture of Membranes (PPROM)
The aim of this study is to compare fetal and maternal outcome in cases of PPROM before 34 weeks versus after 34 weeks.
- Trial name
- NCT03491826
- Testing
- rupture of membrane
- Where
- Egypt
- Volunteers
- 1,011 people
- Sponsor
- sarah mohamed hassan
Pregnancy
Correlation Between PIF Maternal Serum Levels and Pregnancy Outcome
PIF: biomarker of pregnancy, miscarriage, premature birth, preeclampsia, placenta accreta. Except for serum hCG, no pregnancy-complication markers are widely employed to predict the need for medical intervention.
- Trial name
- PIFBlood1 (NCT01805102)
- Where
- 5 sites in United States, France and 1 more
- Volunteers
- 500 people
- Sponsor
- BioIncept LLC
SARS CoV-2, Developmental Disorder
Neurological Development In Toddlers After Maternal SARS-CoV-2 Infection During Pregnancy
Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) is a virus that causes neurological symptoms in a significant proportion of patients in addition to respiratory symptoms.
- Conditions
- SARS CoV-2, Developmental Disorder, Pregnancy Related
- Trial name
- CRONOS-Kids (NCT06968897)
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Obesity
Pregnancy-Related Obesity Prevention Through Education & Communication Technology in AFRICA:The PROTECT-AFRICA STUDY
The purpose of this study is to investigate whether overweight but not obese pregnant African women having unlimited access to a health education-information technology (IT) based intervention package gain weight within the…
- Trial name
- PROTECT-AFRI (NCT01948323)
- Testing
- HEDUAfrica IT package+ standard care
- Where
- 2 sites in South Africa
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Diabetes, Gestational, Pregnancy Diabetic
Long-term Outcome After Gestational Diabetes and Diabetes in Pregnancy
The primary objectives of the proposed project are to assess the long-term effects of prenatal exposure to gestational diabetes or diabetes on the maturation and health of the offspring.
- Trial name
- MuKiLOG (NCT04417452)
- Testing
- Basic data collection (online survey or written form), Physical examination, Psychometric examination
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Jena University Hospital
Analgesia, Epidural, Instrumental Delivery
The Randomised Epidural Analgesia in Term Delivering Women Trial (TREAT)
The objective of the study: to assess the impact of a proactive policy of offering EA at the start of labour as compared to a restrictive policy or care as usual.
- Conditions
- Analgesia, Epidural, Instrumental Delivery, Maternal Outcome, Neonatal Outcome
- Trial name
- TREAT (NCT01261689)
- Testing
- Ropivacaine/ Sufentanil according to local hospital protocol, Care-as usual pain treatment
- Where
- 2 sites in Netherlands
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Maternal Death, Maternal Complication of Pregnancy
Assessing the Maternal Outcome Monitoring Systems
Pregnancy-related death is a growing public health issues, which are of particular concern to minority groups, including African-Americans and Spanish-speaking Latinas.
- Trial name
- MOMS (NCT06415942)
- Testing
- Maternal Outcome Monitoring and Support system
- Where
- 2 sites in United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Columbia University
Maternal Health, Infant Health
Using Advanced Data Systems to Improve Health in Early Life in Rural Nepal
The goal of this cluster randomized controlled trial is to study the effect of a mobile-phone based application used by pregnant women on maternal and newborn health indicators.
- Conditions
- Maternal Health, Infant Health, Institutional Delivery, Birth Preparedness and Complication Readiness
- Trial name
- CITH (NCT05697822)
- Testing
- Mobile Phone and Cloud-based Electronic Contact and Recording System
- Where
- Nepal
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Amit Arjyal