Clinical trials: Mathematics Disorder
Matched-Pair Analysis, Blood Gas Analysis
Mathematical Arterialization of Venous Blood Gas
Objective: Arterial blood gas (ABG) analysis is essential in the clinical assessment of potential acutely ill patients. Venous to arterial conversion (v-TAC), a mathematical method, has recently been developed to convert…
- Conditions
- Matched-Pair Analysis, Blood Gas Analysis, Emergency Service, Hospital
- Trial name
- NCT03309410
- Testing
- Venous to arterial conversion (v-TAC)
- Volunteers
- 30 people
- Sponsor
- Aalborg University
Type 2 Diabetes, Insulin Dependent Diabetes
Mathematical Modeling of Blood Sugar and Hormone Responses in Insulin-Dependent Type 2 Diabetes
This observational study aims to collect detailed metabolic and physiologic data from adults with insulin-dependent type 2 diabetes mellitus following consumption of a mixed meal tolerance test.
- Trial name
- MT2D (NCT07650682)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Depression, Anxiety
Storytelling and Mindfulness for Graduate Student Wellbeing
The purpose of this study is to evaluate an intervention for improving Science, Technology, Engineering, and Math (STEM) graduate student wellbeing.
- Conditions
- Depression, Anxiety, Burnout, Student
- Trial name
- NCT05826860
- Testing
- Mindfulness Practice, Storytelling Workshop
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Diastolic Heart Failure
Mathematical Modeling to Determine Basic Muscle Properties in the Failing Heart
According to the most recent information released by the American Heart Association, heart failure affects 5.8 million Americans and over 23 million people worldwide.
- Trial name
- NCT01778894
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Diabetes Mellitus, Type 1
Carbohydrate Count Aided by a Simulation in People With Type 1 Diabetes Mellitus. A Protocol for a Clinical Trial
Insulin remains the only approved treatment for type 1 diabetes mellitus patients and is used by many with type 2 diabetes. Carbohydrate counting is the most recommended way to prescribe prandial insulin dose because it is safe…
- Trial name
- NCT05181917
- Testing
- STUDIA app
- Where
- Colombia
- Volunteers
- 28 people
- Sponsor
- Hospital Pablo Tobón Uribe
COPD (Chronic Obstructive Pulmonary Disease)
Mathematical Analysis of Signals and Clinical Parameters Provided by Non-invasive Home Ventilation Devices
This study will look at people with COPD who use a home breathing machine called non-invasive ventilation (NIV). NIV machines collect information about your breathing, such as air flow, pressure, and mask leaks.
- Trial name
- SAGE-NIV (NCT07267104)
- Testing
- The intervention involves download data of ventilator with clinical dates of the patient and model ventilator and parameters in acute exacebartion fo COPD
- Where
- Spain
- Volunteers
- 75 people
- Sponsor
- Corporacion Parc Tauli
Metastatic Breast Cancer
A Pilot Dose Escalation Trial of a Densified Chemotherapy Association of Docetaxel and Epirubicin Driven by Mathematical Modeling in Metastatic Breast Cancer Patients: The MODEL1 Study
To determine the maximum tolerated dose of a densified regimen of the association of docetaxel (DTX) and epirubicin (EPI), supported by the concomitant administration of hematopoietic growth factors in patients with metastatic…
- Trial name
- MODEL1 (NCT02392845)
- Testing
- Combination of Docetaxel (DTX) and Epirubicin (EPI)
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Hospices Civils de Lyon
Pancreatic Neoplasms
Pre-planning Mathematical Models in EUS-guided Laser Ablation of Pancreatic Lesions
Pancreatic ductal adenocarcinoma (PDAC) is the fourth cause of cancer death in Western countries. More than 50% of the patients with PDAC has a local advanced or metastatic disease at the time of the diagnosis.
- Trial name
- LA-EUS MOD (NCT05549960)
- Testing
- The medical device used in this study is a 980 nm wavelength diode laser with maximum output of 30 W (EUFOTON Laser Spectrum).
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Campus Bio-Medico University
Well-being in Elementary School Children, Mental Health in Elementary School Children
A Cluster-randomized Control Trial of PAX Good Behavior Game in Swedish Elementary Schools
Two important challenges that primary school in Sweden is confronted by are increasing levels of mental illness among children and adolescents and increasing rates of stress related symptoms and sick leave associated with mental…
- Conditions
- Well-being in Elementary School Children, Mental Health in Elementary School Children, Work-related Stress in Teachers, Academic Performance in Elementary School Children
- Trial name
- NCT05407623
- Testing
- PAX Good Behavior Game, Count on Me!, Collegial Learning Community
- Where
- Sweden
- Volunteers
- 2,184 people
- Sponsor
- Linnaeus University
Cervical Cancer
Molecular Markers in Cervical Cancer Screening in the Feasibility of the Mathematical Markov Model Analysis
The purpose of this study is to: 1. make p16INK4A as a cervical cancer screening of tumor markers, cytology improve existing diagnostic sensitivity, specificity, repeatability and validity, so as to effectively prompted the early…
- Trial name
- NCT00889902
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wuhan University
Substance Abuse
Nurse-Led Heart Math Training Program With Substance Use Disorder
Substance use disorders (SUDs) pose significant challenges to individuals' psychological well-being, resilience, and emotional adjustment.
- Trial name
- HeartMathsub (NCT06437366)
- Testing
- Nurse-Led Heart Math Training Program
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Hemodialysis Complication, Arrhythmias
Potassium Kinetic During and After Hemodialysis and Potassium Profiling to Prevent Arrhythmias
The primary objective of the study is the development of a mathematical model for predicting potassium kinetics during and after the dialytic session. The secondary objectives of the study are: 1.
- Conditions
- Hemodialysis Complication, Arrhythmias, Potassium Imbalance
- Trial name
- PANDORA (NCT04563091)
- Testing
- Hemodialysis with online HFR
- Where
- Italy
- Volunteers
- 6 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Trauma, Critical Illness
Mathematical Modeling of the Acute Inflammatory Response Following Injury
The purpose of this research study is to gather clinical and biologic information from severely injured patients to better understand and characterize the host response to injury and inflammation across several domains.
- Trial name
- NCT00250523
- Where
- United States
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- National Institute of General Medical Sciences (NIGMS)
Breast Cancer
Mathematical Modeling to Predict Response to Neoadjuvant Chemotherapy in Breast Cancer
This is a feasibility study evaluating the use of a mathematical model to predict response to standard neoadjuvant anthracycline / taxane based chemotherapy in patients with breast cancer.
- Trial name
- NCT03983538
- Testing
- Mathematical modeling to predict response to chemotherapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- New Mexico Cancer Research Alliance
Cognition Disorder, Brain Mapping
Facilitating Numerical Processing With Transcranial Stimulation in Developmental Dyscalculia
Background: Developmental dyscalculia is a learning disability in which individuals have difficulty learning or comprehending mathematics or other number concepts (such as keeping score during games, measuring time, or estimating…
- Trial name
- NCT01195961
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Atherosclerosis, Stent Complication
Fatigue Behavior of Peripheral STENt of the Superficial Femoral Artery
Endovascular treatment of superficial femoral artery stenosis/obstruction is still the subject of debate in the scientific literature.
- Trial name
- FASTEN-PRO (NCT06198920)
- Testing
- Stenting of the superficial femoral artery
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Policlinico S. Donato
Polycystic Ovary Syndrome, Endometriosis
Mathematical Model for the Human Menstrual Cycle, Endocrinological Diseases and Fertility Treatment-PAEON
Development of a bio-mathematical model of the human female cycle
- Conditions
- Polycystic Ovary Syndrome, Endometriosis, Hyperprolactinemia
- Trial name
- PAEON (NCT02098668)
- Testing
- Fertility treatment
- Where
- Switzerland
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Thyroid Diseases, Congenital Hypothyroidism
Prospective Evaluation of OptiThyDose
The aim of this multicentric, randomised, two-arms and single-blinded clinical trial is to prospectively evaluate OptiThyDose for Congenital hypothyroidism (CH) and Graves' disease (GD).
- Conditions
- Thyroid Diseases, Congenital Hypothyroidism, Graves Disease
- Trial name
- NCT06864351
- Testing
- OptiThyDose
- Where
- 7 sites in Armenia, France and 1 more
- Volunteers
- 150 people
- Sponsor
- University Children's Hospital Basel
Anomalous Coronary Artery Origin, Anomalous Coronary Artery Arising from the Opposite Sinus
New Patient-specific Functional Assessment of the Anomalous Aortic Origin of Coronary Arteries.
Anomalous Aortic Origin of the Coronary Arteries (AAOCA) is a rare congenital disease that may cause sudden death in young subjects.
- Conditions
- Anomalous Coronary Artery Origin, Anomalous Coronary Artery Arising from the Opposite Sinus, Anomalous Coronary Artery Course, Anomalous Coronary Artery with Aortic Origin and Course Between the Great Arteries
- Trial name
- NECESSARY (NCT05159791)
- Testing
- Invasive coronary blood flow assessment and simulations and fluid dynamic patient specific simulation
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Policlinico S. Donato
Math Learning Disability
Understanding Cognitive-Academic Bidirectionality in Math Learning Disabilities
The goal of this clinical trial is to test the effects of an innovative intervention designed to improve math skills in first graders at risk for math disabilities.
- Trial name
- NCT07220746
- Testing
- Coordinated Treatment, Math Treatment
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Vanderbilt University