Clinical trials: Mature Teeth
Apical Periodontitis
Assessment of Different Disinfection Protocols on Regenerative Potential of Mature Teeth
Regenerative endodontic procedures have been used to successfully treat human mature permanent teeth with necrotic pulps and apical periodontitis.
- Trial name
- NCT05557994
- Testing
- Method
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Minia University
Necrotic Pulp, Periapical; Infection
Volume Assessment of the Periapical Healing Following Regenerative Endodontic Procedures Using Cone- Bean Computed Tomography
3D volume assessment was done to evaluate the periapical healing following REPs in mature teeth.
- Trial name
- NCT04646538
- Testing
- Regenerative Endodontics Procedures (REPs)
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Concerned Growth Factor Versus Miniral Trioide Aggregate in Management of Mature Permanent Molar With Irreversible Pulpitis
Concerned Growth Factor VS Miniral Trioide Aggregate in Treatment of Mature Permanent Teeth of Children With Symptomatic Irreversible Pulpitis.
Concerned Growth factor versus Miniral Trioide aggregate in management of Mature permanent Molar of children with irreversible pulpitis
- Trial name
- NCT07138287
- Testing
- Concerned Growth factor in management of Mature permanent Molar with irreversible pulpitis
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Minia University
Pulpitis - Irreversible
A-prf,Nanochitosan Combined With A-prf Compared to Chitosan for Symptomatic Irreversible Pulpitis of Mature Teeth
Clinical and radiographic assessment of A-prf,A-prf combined with nanochitosan compared to chitosan for symptomatic irreversible pulpits in lower permanent first molar
- Trial name
- NCT06438523
- Testing
- PULPOTOMY OF MATURE PERMENANT TEETH
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Dental Pulp Necroses
Efficacy of Regenerative Endodontic Treatment With PRF as a Secondary Treatment of Mature Necrotic Incisors in Adolescents
Evalaution of clinical success of secondary treatment for total 40 permanent incisors with failed root canal treatment with apical radiolucency.
- Trial name
- PRF (NCT05517187)
- Testing
- no intervention, Platelet rich fibrin
- Where
- 2 sites in Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nahda University
Drug Effect
Evaluation of Antibacterial Effect of Allium Sativum, Calcium Hydroxide and Their Combination in Infected Mature Teeth
This study was to evaluate and compare garlic extract antibacterial effect when used as an intra-canal medicament in infected mature anterior teeth with calcium hydroxide and a mixture of calcium hydroxide and garlic, using real…
- Trial name
- Garlic (NCT05050071)
- Testing
- Allium Sativum, Polymerase chain reaction
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Pulpitis - Irreversible
Assessing Success of MTA and Pre-mixed Bioceramic in Mature Teeth With Irreversible Pulpitis With Full Pulpotomy.
Although many pulpotomy agents are commercially available, there is a dearth of clinical research comparing the efficacy of these agents in treating individuals with irreversible pulpitis.
- Trial name
- GCP (NCT05853185)
- Testing
- Pro Root MTA®, EBRRM®
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Liaquat University of Medical & Health Sciences
Pulpitis - Irreversible, Pulpitis
Vital Pulp Therapy vs. Root Canal Treatment in Mature Teeth With Irreversible Pulpitis
This study was designed as a prospective, randomized, controlled clinical trial with parallel groups and double blinding, following the principles of the Declaration of Helsinki for human experimentation and in accordance with…
- Conditions
- Pulpitis - Irreversible, Pulpitis, Pulpotomy, Root Canal Therapy
- Trial name
- NCT07355140
- Testing
- VPT Group and RCT Group
- Where
- Venezuela
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Universidad Central de Venezuela
Post-operative Pain
Using Three Different Final Irrigants and Showing Their Effects on the Success of Revascularization
this study will assess different irrigating materials on the success revascularization of necrotic mature teeth associated with PRF.
- Trial name
- NCT03591172
- Testing
- Propolis, Nano-propolis, saline
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulp Necroses
Comparison Between Two Regenerative Scaffolds
This study was performed to compare endodontic regeneration outcome in necrotic mature single rooted teeth with periapical radiolucency using platelet rich fibrin (PRF) \& concentrated growth factor (CGF) as a different natural…
- Trial name
- NCT06227533
- Testing
- Endodontic regeneration using concentrated growth factor compared with Platelet rich fibrin
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Pulp Necroses, Periapical Lesion
Magnetic Resonance Imaging (MRI) of Pulp Regeneration
The present study was conducted to test whether pulp-like tissue can be regenerated in mature teeth with closed apex? And whether the size of the apical diameter affects the success of REPs? And whether Magnetic resonance imaging…
- Conditions
- Pulp Necroses, Periapical Lesion, Regeneration
- Trial name
- NCT03804450
- Testing
- Regenerative endodontic procedures (REPs)
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Irreversible Pulpitis, Mature Teeth
Effectiveness of Pulpotomy in the Management of Mature Permanent Tooth With Irreversible Pulpits
This study is to evaluate the effectiveness of pulpotomy in mature permanent tooth with irreversible pulpits, and compare the clinical efficacy of pulpotomy and root canal therapy.
- Trial name
- NCT05622266
- Testing
- Pulpotomy, Root Canal Therapy
- Where
- China
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Pulpitis, Pulp Exposure, Dental
Pulpotomy in Carious Permanent Mature Teeth: Pulp Survival and Risk Factors
This Trial evaluated the extent of pulp survival following pulpotomy in the permanent tooth pulp exposed by caries and identify potential risk factors for pulpal complications.
- Conditions
- Pulpitis, Pulp Exposure, Dental, Pulp and Periapical Tissue Disease
- Trial name
- NCT03490422
- Testing
- Pulpotomy
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- National University Health System, Singapore
Dental Pulp Capping, Dental Caries Extending to Pulp
Long-term Evaluation of Direct Pulp Capping
Calcium hydroxide and mineral trioxide aggregate have been used in vital pulp therapy with variable outcomes recorded by different study.
- Trial name
- NCT03403985
- Testing
- Calcium Hydroxide (Ca(OH)2), Mineral Trioxide Aggregate
- Where
- Jordan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Pulpitis - Irreversible
Prognostic Biomarkers for Pulpotomy Outcome
This study will recruit 180 molars diagnosed with irreversible pulpitis. Full pulpotomy will be performed on 120 teeth, while RCT (root canal treatment) will be conducted on another cohort of 60 teeth as the control for assessing…
- Trial name
- NCT06514053
- Testing
- Full pulpotomy, Root canal treatment
- Where
- Hong Kong
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Vital Pulp Therapy
Vital Pulp Therapy of Mature Permanent Teeth With Irreversible Pulpitis Using Bioceramic Material
This clinical trial is designed to study and compare the effect of two different types of chelating agents on the vital pulp therapy of mature permanent teeth with irreversible pulpitis using bioceramic material.
- Trial name
- NCT05970536
- Testing
- Apple vinegar or EDTA 17%
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sinai University
Pulp Revascularization
Outcome of Pulp Revascularization of Necrotic Mature Permanent Teeth Using Platelet-rich Fibrin
Regenerative endodontic procedures are intended to replace damaged tooth structures, including dentine and root structures, in addition to cells of the pulp-dentine complex.
- Trial name
- NCT06347640
- Testing
- induced bleeding, plasma rich fibrin
- Where
- Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Pulpitis
MMP-9 Expression in Permanent Mature Teeth With Symptomatic Pulpitis
Matrix metallopeptidase-9 (MMP-9) expression was compared in healthy and inflamed pulp and the outcome of coronal pulpotomy in teeth with symptomatic pulpitis was assessed.
- Trial name
- NCT03807674
- Testing
- Coronal pulpotomy
- Where
- Lithuania
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Eglė Gvazdaitytė
Irreversible Pulpitis
The Influence of Magnification and Clinical Experience on the Outcome of Pulpotomy in Mature Adult Teeth
The goal of this interventional randomized clinical trial is to test the effect of magnification and clinical experience of the operator on the success rate of full pulpotomy in mature adult molar teeth.
- Trial name
- NCT06231290
- Testing
- Adult full pulpotomy procedure
- Where
- Egypt
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Irreversible Pulpitis
Evaluation of Two Different Calcium Silicate Cements as a Treatment for Irreversible Pulpitis in Mature Molars
This randomized controlled clinical trial aims to evaluate the effect of two calcium silicate cements-Biodentine and EndoCem-on post-operative pain and treatment success in vital pulp therapy (VPT) for mature permanent mandibular…
- Trial name
- NCT07066410
- Testing
- intervention 1: endocem, Intervention 1: biodentine
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- British University In Egypt