Clinical trials: Maxillary Neoplasms
Oral Cavity Squamous Cell Carcinoma
Helical CT, PET/CT, MRI, and CBCT Alone or in Combination in Predicting Jaw Invasion in Patients With Oral Cancer
This clinical trial studies how well helical computed tomography (CT), positron emission tomography (PET)/CT, magnetic resonance imaging (MRI), and cone beam computed tomography (CBCT) work alone or in combination in predicting…
- Trial name
- NCT03053960
- Testing
- Computed Tomography, Positron Emission Tomography and Computed Tomography Scan, Cone-Beam Computed Tomography
- Volunteers
- 8 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Trigeminocardiac Reflex, Jaw Cysts
Assessing the Frequency of Trigeminocardiac Reflex in Maxillary and Mandibular Cyst Operations
The goal of this clinical trial is to investigate the frequency of trigeminocardiac reflex development during the surgical removal of large cystic structures within the maxillary and mandibular bones in healthy adults.
- Conditions
- Trigeminocardiac Reflex, Jaw Cysts, Hemodynamic Instability
- Trial name
- NCT06605716
- Testing
- Enucleation of cysts
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Head and Neck Cancer, Pain, Musculoskeletal
Continous Popliteal Block for Microvascular Free Flap Reconstruction in Ear, Nose and Throat Surgery
The aim of the study is to assess the effects of a continuous popliteal block on postoperative pain and recovery after major ear, nose and throat surgery with microvascular free flap reconstruction using a fibula graft.
- Trial name
- NCT03607227
- Testing
- Levobupivacaine, Saline Solution
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Region Skane
Mucormycosis
Rehabilitation With an Obturator in Maxillary Defects
During the COVID-19 pandemic, there was a lot of reporting of COVID-19-associated mucormycosis cases. Managing this condition posed a new challenge to clinicians.
- Trial name
- NCT06515743
- Testing
- Obturator Prosthetic Rehabilitation
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Menoufia University
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer
This phase I/Ib trial tests the safety and best dose of ipatasertib in combination with the usual treatment approach using chemotherapy together with radiation therapy ("chemo-radiation") in patients with head and neck cancer.
- Conditions
- Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Head and Neck Carcinoma of Unknown Primary, Locally Advanced Head and Neck Squamous Cell Carcinoma
- Trial name
- NCT05172245
- Testing
- Biopsy Procedure, Biospecimen Collection, Cisplatin
- Where
- 18 sites in United States, Canada
- Volunteers
- 46 people
- Sponsor
- National Cancer Institute (NCI)
Mandibular Neoplasms, Maxillary Neoplasms
Three-Dimensional Printing of Patient-Specific Titanium Plates in Jaw Surgery: A Pilot Study
Medical titanium plates are routinely used in fixing mobilized bone segments in jaw surgeries. Generally these plates are commercialized with standard construction specifications.
- Conditions
- Mandibular Neoplasms, Maxillary Neoplasms, Dentofacial Deformities, Maxillofacial Injuries
- Trial name
- 3DJP16 (NCT03057223)
- Testing
- 3D-printed patient-specific titanium plates
- Where
- Hong Kong
- Volunteers
- 96 people
- Sponsor
- The University of Hong Kong
Maxillary Neoplasms
Prevalence of Trismus in Patients With Maxillary Cancer With and Without Radiation Therapy in the Egyptian Population.
This study aims at evaluating the prevalence of trismus among maxillary cancer patients in the Egyptian population and the effect of radiotherapy on the occurrence of trismus.
- Trial name
- NCT05091814
- Testing
- radiotherapy
- Where
- Egypt
- Volunteers
- 360 people
- Sponsor
- Cairo University
Maxillary Sinus Neoplasms
Temporalis Myofascial Flap Effectiveness
This research is conducted as trial to improve lifestyle of patients with cranio-maxillofacial defects following major insults like trauma or tumor resection in form of speech problems or dysphagia by usage temporalis myofascial…
- Trial name
- NCT05298969
- Testing
- Temporalis Myofascial flap
- Where
- Egypt
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cancer Maxilla
Results of Different Modalities of Palatomaxillary Reconstruction
Results of different modalities of reconstruction after maxillectomy , prospective comparative study
- Trial name
- NCT07124988
- Testing
- regional flap, distant flap
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Sohag University
Maxillary Deficiency, Head and Neck Neoplasms
Predictors of Patient-Reported Outcomes for Maxillectomy Patients
The success of digitally fabricated obturator rehabilitation is determined not only by the prosthesis itself but also by the interaction between patient characteristics, oncologic history, prosthetic support, and…
- Trial name
- NCT07864974
- Testing
- Digitally Fabricated Obturator Prosthesis
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Dr. Merve Benli
Mandibular Neoplasms, Maxillary Neoplasms
3D-Printed Patient-Specific Surgical Plates Versus Conventional Surgical Plates in Jaw Reconstruction
Objectives: The aim of this randomised controlled clinical trial is to evaluate surgical accuracy and efficiency of computer-assisted jaw reconstruction using 3D-printed patient-specific titanium surgical plates versus…
- Conditions
- Mandibular Neoplasms, Maxillary Neoplasms, Dentofacial Deformities
- Trial name
- NCT04635865
- Testing
- 3D-printed patient-specific plate, Conventional commercial reconstruction plate
- Where
- Hong Kong
- Volunteers
- 92 people
- Sponsor
- The University of Hong Kong
Maxillary Neoplasms
PEEK Versus Metallic Attachment-retained Obturators
Patients' satisfaction evaluation and radiographic evaluation of the terminal abutments of attachment- retained maxillary obturators with metal framework versus milled PEEK framework in the management of maxillectomy cases.
- Trial name
- PEEK (NCT04778254)
- Testing
- PEEK attachment retained obturator, metalic attachment retained obturator, conventional obturator
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Cairo University
Odontogenic Maxillary Cysts
Effect of Biphasic Bone Graft Material With Autologous Platelet-rich Fibrin on Bone Regeneration in a Maxillary Cyst
Effect of Biphasic Bone Graft Material (BGM) in combination with autologous platelet-rich fibrin (PRF) on bone regeneration in an odontogenic maxillary cyst: a randomized clinical trial
- Trial name
- NCT03003013
- Testing
- Biphasic Bone Graft Material (BGM) in Combination With Autologous Platelet-rich Fibrin (PRF)
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Head and Neck Carcinoma, Hypopharyngeal Carcinoma
Exercise Training and Behavioral Modification for the Improvement of Physical Activity in Head and Neck Cancer Patients Undergoing Cancer Treatment
This clinical trial evaluates the tolerability of a physical activity program in head and neck cancer patients who are undergoing cancer treatment.
- Conditions
- Head and Neck Carcinoma, Hypopharyngeal Carcinoma, Laryngeal Carcinoma, Maxillary Sinus Carcinoma
- Trial name
- NCT04788264
- Testing
- Medical Device Usage and Evaluation, Consultation, Exercise Intervention
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Thomas Jefferson University
Maxillary Cyst
Deproteinized Bovine Bone in Alveolar Bone Critical Size Defect (>2cm) Secondary to Cyst Removal
The aim of this study was to evaluate the effect of the use of deproteinized bovine bone as a filler material of critical-sized (diameter >=20 mm) bony defects derived from the excision of maxillary and mandibular cysts.
- Trial name
- NCT02612740
- Testing
- Deproteinized bovine bone, granules of deproteinized bovine bone (Bio-Oss)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Padova, School of Dental Medicine
Oral Tumor
Vascularized Free Fibula Flap and Computer-guided Implant Surgery
The rehabilitation of patients affected by defects of the jaws after tumor resection is still very challenging. Resection can lead to significant facial deformity, impaired oral functions such as speech, swallowing, saliva…
- Trial name
- NCT01561534
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- University of Bari
Maxillary Cyst
Using of Bone Marrow Stem Cell Concentrate with Platelet Rich Fibrin and Bone Graft in Bone Reconstruction of Upper Jaw Bony Cystic Defects, Comparing with Platelet Rich Fibrin with Bone Graft
Will the use of bone marrow stem cells with platelet rich fibrin enhance and accelerate the bone regeneration in the upper jaw cystic defects ?
- Trial name
- NCT06662604
- Testing
- Bone marrow stem cells concentrate , platelet rich fibrin , bone graft, platelet rich fibrin and bone graft
- Volunteers
- 22 people
- Sponsor
- Cairo University
Maxillary Neoplasms
Reconstruction of Maxillary and Midfacial Defects Using Latissimus Dorsi Scapular Free Flaps
Bony reconstruction of the midface with free tissue transfer is complex and challenging due to structural considerations such as the need for orbital support, patency of the nasal cavity, restoration of the palate and alveolus…
- Trial name
- NCT04522700
- Testing
- scapular free flap
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- hassan harby mohamed
Maxillary Tumors
Aesthetic Reconstruction of Onco-surgical Maxillary Defects Using FSF With and Without CAD/CAM Customized Cutting Guide
The aim of the study is to compare aesthetic results and operation time of Free Scapular flap with and without CAD/CAM customized osteotomy guide for reconstruction of maxillary Defects.
- Trial name
- NCT03757286
- Testing
- FSF with CAD\CAM customized cutting guide, FSF without customized cutting guide
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Cairo University
Alveolar Bone Grafting, Bone Augmentation
Bone Augmentation Using Particulated Biomaterial and Autogenous Bone, Stabilized by Collagen Membrane and Pins (PaMP)
Twenty four patients with bone resorption on the anterior maxilla will be divided into two groups with different kinds of grafting: bone block associated with particulated biomaterial and particulated mixture of autogenous bone…
- Trial name
- PaMP (NCT02406924)
- Testing
- Biopsy, Computerized Tomography, Standardized periapical radiographs
- Volunteers
- 24 people
- Sponsor
- Pedro Tortamano