Clinical trials: Maxillofacial Deformity
Buccal Fat Pad, Cleft Palate
Evaluating Salivary α - Amylase Levels Following Trigona Sp Honey Application To Post Palatoplasty Patients: A Pilot Randomized Clinical Study
Palatoplasty is a surgical procedure performed to restore palatal continuity and improve velopharyngeal function in patients with cleft palate.
- Conditions
- Buccal Fat Pad, Cleft Palate, Honey, Salivary Alpha Amylase
- Trial name
- NCT07610993
- Testing
- Trigona sp honey with the buccal fat pad technique, framicetyn sulfate dressing with the buccal fat pad technique, Trigona sp. honey dressing without the buccal fat pad technique
- Where
- Indonesia
- Volunteers
- 24 people
- Sponsor
- Hasanuddin University
Maxillar Hypoplasia
Evaluation of Masticatory Muscle Activity in Pediatric Patients Undergoing Rapid Maxillary Expansion
Transverse maxillary constriction is a malocclusion that subsists when the distance between the upper first molars palatal cuspids is lower than the distance between the lower first molars vestibular center fossae.
- Trial name
- NCT05820438
- Testing
- Electromyography
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- University of Pavia
Maxillofacial Abnormalities
Does Subspinal Le Fort I Osteotomy Affect the Nasal Airway Volume
After the description of Le Fort fractures, maxillary osteotomies are used to correct dentofacial deformities. The profile changes on nasolabial region resulting from a Le Fort I osteotomy, also that affects nasal airway.
- Trial name
- NCT06281197
- Testing
- Conventional, Subspinal
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Cleft Lip and Palate
Three Dimensional Facial Growth Analysis
Cleft lip and palate is the most common facial birth defect affecting one in 700 babies, and frequently leads to problems in feeding, breathing, speech and/or hearing, and aesthetic problems often leading to social and…
- Trial name
- NCT03514563
- Testing
- MRI imaging, Optical scan, 3D photography
- Where
- United Kingdom
- Volunteers
- 1 people
- Sponsor
- University of Hull
Cleft Palate, Hemorrhage
Acid Tranexamic Effectiveness in Reducing the Intraoperative Bleeding in Palatoplasty
Randomized study evaluating the role of tranexamic acid in reducing intraoperative bleeding in palatoplasty.
- Trial name
- NCT02422056
- Testing
- Tranexamic Acid, Saline
- Volunteers
- 66 people
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Cleft Lip and Cleft Palate, Cleft Lip Palate
Early Intervention in Infants With Unrepaired Cleft Palate: Language, Palatal Function, and Articulation.
The goal of this clinical trial is to learn if teaching speech skills to infants with cleft palates, prior to palate repair, will help them to develop speech and language skills.
- Conditions
- Cleft Lip and Cleft Palate, Cleft Lip Palate, Cleft Lip and/or Palate, Cleft Palate
- Trial name
- NCT07219901
- Testing
- Early intervention for language, articulation and palatal function skills
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Old Dominion University
Cherubism
Genetic and Functional Analysis of Cherubism
The goal of this research study is to identify genes and regulatory elements on chromosomes that cause cherubism. Together with the investigators collaborators the investigators also study blood samples and tissue samples from…
- Trial name
- CBM (NCT01630447)
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- UConn Health
Cleft Palate
Comparison of Different Feeding Appliances for Cleft Palate Babies
This study will compare flexible , rigid feeding plates and a special feeding bottle for children with cleft palate.
- Trial name
- NCT06103162
- Testing
- flexible feeding plate
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University
Maxillofacial Deformity, Maxillofacial Abnormalities
a Comparative Analysis of Subspinal and Conventional Le Fort I Osteotomy on Nasolabial Soft Tissues
Following surgical operations, patients have aesthetic expectations as well as functional ones. To minimize undesirable aesthetic results after surgery and to increase the effectiveness of the surgery, the surgical method used…
- Conditions
- Maxillofacial Deformity, Maxillofacial Abnormalities, Maxillo-facial Surgery
- Trial name
- NCT07549659
- Testing
- conventional le fort I osteotomy type, subspinal le fort I osteotomy type
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Premature Infants, Pierre Robin Sequence
Comparison of Sucking in Premature Infants and Infants With Pierre Robin Sequence
The NUTROBIN study aims to analyze sucking in two populations of vulnerable children who require intensive and prolonged care, and whose treatment has an impact on the subsequent development of oral function.
- Conditions
- Premature Infants, Pierre Robin Sequence, Feeding Disorder
- Trial name
- NUTROBIN (NCT07604818)
- Testing
- Succiometry
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Hospices Civils de Lyon
Malocclusion, Angle Class II, Malocclusion, Angle Class III
Comparing 3D-Printed and Milled Titanium Plates in Jaw Surgery (Le Fort I): Accuracy and Operative Time
The purpose of this study is to find out if 3D printed patient-specific titanium plates improve surgical accuracy and decrease operative time compared to milled patient-specific titanium plates in patients having Le Fort I…
- Conditions
- Malocclusion, Angle Class II, Malocclusion, Angle Class III, Dentofacial Deformities, Osteotomy, Le Fort I
- Trial name
- TiPlateRCT (NCT07841067)
- Testing
- 3D-Printed Patient-Specific Titanium Plates, Milled Patient-Specific Titanium Plates
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Future University in Egypt
Post-Traumatic Orbital Deformity
Resorbable Polymer Plates in Repair of Blowout Orbital Floor Fractures
It is a prospective study to evaluate the use of resorbable plates for the repair of blow out orbital floor fractures over a follow up period of one year at both cosmetic and functional levels.
- Trial name
- NCT03683615
- Testing
- repair of orbital floor fractures using resorbable plates
- Volunteers
- 20 people
- Sponsor
- Minia University
Malocclusion, Anxiety
Patient Education Before Orthognathic Surgery
To evaluate the effectiveness in the use of an educational material through: Assessment of knowledge about post-operative orthognathic surgery; assessing levels of anxiety with the survey of Anxiety Inventory-STATE-TRAIT…
- Conditions
- Malocclusion, Anxiety, Micrognathism, Prognathism
- Trial name
- NCT01803204
- Testing
- Booklet - Preoperative Educational
- Where
- Brazil
- Volunteers
- 48 people
- Sponsor
- University of Sao Paulo
Cleft Palate, Pain
Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following cleft palate surgery in infants and young children.
- Conditions
- Cleft Palate, Pain, Postoperative Care, Perioperative Care
- Trial name
- OPAL-Cleft (NCT06962306)
- Testing
- Methadone hydrochloride, Fentanyl/Hydromorphone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Zygomatic Fractures
Evaluation of Navigation Assisted Reconstruction of Posttraumatic Zygomatic Deformity
Treatment of late deformities following fractures of the orbitozygomaticomaxillary complex can be considered a formidable challenge, even to the skilled surgeon.
- Trial name
- NCT01487018
- Testing
- Navigation Surgery, Traditional Surgery
- Where
- China
- Volunteers
- 103 people
- Sponsor
- Peking University
Surgical Complication, Paresthesia
Trial of Bilateral Sagittal Split Osteotomy Induced Paresthesia Using Ultrasonic vs. Reciprocating Saw Instrumentation
The aim of this prospective study is to analyze the postoperative paresthesias experienced in patients who undergo bilateral sagittal split osteotomies (BSSO) using an ultrasonic saw, versus a reciprocating saw.
- Conditions
- Surgical Complication, Paresthesia, Fracture, Nerve Injury
- Trial name
- NCT05205616
- Testing
- Sonopet ultrasonic saw, Reciprocating saw
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cleft Lip, Cleft Palate
Allied Cleft & Craniofacial Quality-Improvement and Research Network (ACCQUIREnet)
The Allied Cleft \& Craniofacial Quality-Improvement and Research Network (ACCQUIREnet) is a group of multidisciplinary cleft teams that have implemented a system for prospective collection of outcomes data, based on the ICHOM…
- Conditions
- Cleft Lip, Cleft Palate, Cleft Lip and Palate
- Trial name
- ACCQUIREnet (NCT02702869)
- Testing
- cleft lip repair, cleft palate repair, oronasal fistula repair
- Where
- 11 sites in United States, Canada
- Volunteers
- 1,000 people
- Sponsor
- Duke University
Mandible Tumor, Mandibular Injuries
Evaluation of EpiBone-CMF for Mandibular Ramus Reconstruction
EpiBone-Craniomaxillofacial (EB-CMF) is an autologous, anatomically shaped bone graft created specifically for the patient's defect, using the patients own adipose-derived mesenchymal stem cells.
- Conditions
- Mandible Tumor, Mandibular Injuries, Mandible; Deformity
- Trial name
- EB-CMF (NCT03678467)
- Testing
- EB-CMF
- Where
- 3 sites in United States
- Volunteers
- 6 people
- Sponsor
- Epibone, Inc.
Implant Site Reaction, Maxillary Deficiency
Radiographic Assessment of Bone Gain Following Sinus Lifting With Simultaneous Implant Placement Using Crestal Approach With Membrane Control Technique for Bone Augmentation of Atrophied Maxillary Posterior Ridge
This study aims to evaluate the quantity and quality of the native and the newly bone around dental implants that's simultaneously installed with sinus lifting
- Trial name
- NCT06446687
- Testing
- Dental implant with sinus lifting.
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Adiposity, Micrognathism
A Fatty Flap Taken From the Double Chin for Chin Enhancement: a New Surgical Technique
The double chin is a troublesome component of the lower third of the face. It gives an embarrassing and unpleasant facial appearance to both men and women leading them to ask for liposuction.
- Trial name
- NCT05515016
- Testing
- chin enhancement with a fatty flap sculpted from the double chin
- Volunteers
- 10 people
- Sponsor
- Mohamed Tahar Maamouri University Hospital