Clinical trials: Maxillofacial Deformity
Cleft Palate, Unilateral Cleft Palate
Palatoplasty Techniques Using PRF and Gentamicin-Loaded PRF in Cleft Palate
This prospective, randomized controlled trial evaluates the clinical efficacy of autologous Platelet-Rich Fibrin (PRF) and Gentamicin-Loaded PRF as regenerative and antimicrobial biological adjuncts in primary palatoplasty.
- Conditions
- Cleft Palate, Unilateral Cleft Palate, Bilateral Cleft Palate, Complete Cleft Palat
- Trial name
- NCT07752849
- Testing
- Standard palatoplasty ( control), Platelet _ Rich Fibrin ( PRF), gentamicin_ loaded PRF
- Where
- Yemen
- Volunteers
- 90 people
- Sponsor
- Al-Thawra Modern General Hospital
Pierre Robin Sequence
Pierre Robin Sequence Outcome Assessment Multi Institutional Study
The purpose of this prospective, multi-center, longitudinal study is to assess clinical outcomes related to the surgical treatment of PRS ( Pierre Robin Sequence) by MDO (Mandibular distraction osteogenesis).
- Trial name
- PROMIS (NCT02432638)
- Where
- United States
- Sponsor
- NYU Langone Health
Cleft Palate
Optic Nerve Sheath Diameter in Patients Undergoing Palatoplasty
The purpose of this study is to evaluate the change of the optic nerve sheath diameter according to the change of the neck position in pediatric patients undergoing palatoplasty.
- Trial name
- NCT03585608
- Testing
- Neck extension
- Where
- 2 sites in South Korea
- Volunteers
- 30 people
- Sponsor
- Asan Medical Center
Intubation; Difficult or Failed
Comparison of Two Airway Devices in Paediatric Patients With Difficult Airway
The aim of current study was to compare Flexible fiberoptic bronchoscopy (FFB) and Glidescope devices in terms of intubation success and duration of intubation in patients under 12 months of age with PRS.
- Trial name
- NCT06767995
- Testing
- Flexible fiberoptic bronchoscopy, Glidescope
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hacettepe University
Cleft Palate Children, Speech Sound Disorder
Speech Intervention Via Telepractice for Children With Repaired Cleft Palate
The goal of this interventional study is to see if online speech therapy works just as well as face-to-face speech therapy in children with cleft palate.
- Trial name
- NCT07434375
- Testing
- Speech therapy via teleprace, Face-to-face speech therapy
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Texas Tech University Health Sciences Center
Cleft Palate, Cleft Palate, Unilateral, Complete
MRI Assessment of Velopharyngeal Anatomy After Modified Furlow-Buccinator Flap in Late Primary Palate Repair
The goal of this case series study is to learn if magnetic resonance imaging (MRI) can show how well the palate and throat muscles work at rest and during speech after late cleft palate repair.
- Conditions
- Cleft Palate, Cleft Palate, Unilateral, Complete, Cleft Lip, Cleft Alveolus and Cleft Palate, Cleft Palate Repair
- Trial name
- NCT07514091
- Testing
- Modified Furlow Palatoplasty combined with buccinator myomucosal flap
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Cairo University
Cleft Palate
Optic Nerve Sheath Diameter Measurement in Cleft Palate Repair
The aim of this study is to evaluate the effect of the Boyle-Davis mouth opener, which is routinely used in cleft palate surgery, on intracranial pressure by USG-guided optic nerve sheath diameter measurement, which is a…
- Trial name
- NCT04718558
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Karadeniz Technical University
Pierre Robin Syndrome
Effect of Oral Feeding in Infants With Pierre Robin Syndrome
This was a randomized controlled study. The infants enrolled were randomly divided into the IOE group (with Intermittent Oro-Esophageal Tube Feeding) and the PNG group (with Nasogastric Tube Feeding), all receiving systemic…
- Trial name
- NCT06328959
- Testing
- intermittent oro-esophageal tube feeding, gastric tube feeding
- Volunteers
- 60 people
- Sponsor
- Copka Sonpashan
TMJ Disorder, Mandibular Deficiency
Virtual Planning of Total TMJ Replacement
Virtual Planning of Total TMJ Replacement
- Conditions
- TMJ Disorder, Mandibular Deficiency, TMJ Ankylosis
- Trial name
- TJR (NCT07643259)
- Testing
- Custom made TMJ
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Faculty of Dental Medicine for Girls
Maxillary Prognathism, Maxillary Retrusion
Custom Made Plate in Orthognathic Surgery
Orthognathic surgery has traditionally been used to correct dentofacial deformities. Conventional methods rely on 2D radiographic images, occlusal splints, and dental casts, but these approaches have limitations, such as errors…
- Trial name
- OGS (NCT06772688)
- Testing
- orthognathic surgery
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Faculty of Dental Medicine for Girls
Impacted Teeth
Exact Localisation of Impacted and Supernumerary Teeth by Cone Beam Computer Tomography
The purpose of this investigation is an exact preoperative 3D-localisation of impacted and supernumerary teeth in the maxilla using Cone Beam Computer Tomography
- Trial name
- NCT01002131
- Testing
- CBCT
- Where
- Norway
- Volunteers
- 61 people
- Sponsor
- Norwegian University of Science and Technology
Otitis Media, Cleft Palate
Furlow Palatoplasty With Tensor Tenopexy
This study compares a standard method for palate repair (the Furlow palatoplasty) with a modification of that method to determine which, if either, is more effective in reducing the duration of middle-ear disease (fluid in the…
- Trial name
- NCT01535131
- Testing
- palatoplasty
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- University of Pittsburgh
Pierre Robin Syndrome
Effect of Oral Feeding in Infants With Pierre Robin Syndrome
This was a randomized controlled study. The infants enrolled were randomly divided into the IOE group (with Intermittent Oro-Esophageal Tube Feeding) and the PNG group (with Nasogastric Tube Feeding), all receiving systemic…
- Trial name
- NCT06267950
- Testing
- systematic therapy, intermittent oro-esophageal tube feeding, gastric tube feeding
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Zeng Changhao
Maxillofacial Abnormalities, Mandible Prognathism
Condylar Position Changes and TMJ Functions After BSSO Mandibular Setback, Low Medial Cut.
This study hypotheses that using low medial cut osteotomy BSSO in mandibular setback can be an efficient and effective method to limit the bony segment interferences , decreasing muscles stripping during osteotomy ,decrease…
- Conditions
- Maxillofacial Abnormalities, Mandible Prognathism, Skeletal Malocclusion
- Trial name
- NCT05713084
- Testing
- mandibular setback using BSSRO
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Maxillary Deficiency
Paranasal Sinus Volumes of Maxillary Deficiency Patients Requiring Le Fort Osteotomy
The present study aims to compare ethmoid, sphenoid and maxillary sinus volumes of patients with maxillary deficiency requiring Le Fort osteotomy with healthy patients, by employing computed tomography imaging.
- Trial name
- NCT04637568
- Testing
- Computerized tomography
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara University
Mandibular Retrognathism, Mandibular Hypoplasia
Twin Block Appliance in Incremental Versus Maximum Bite Advancement in Skeletal Class II
The aim of this study is to compare to different protocols to treat Class II malocclusion in growing subjects using the twin block appliance
- Trial name
- NCT04562545
- Testing
- Modified Twin Block, Twin Block Appliance set to maximum bite
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Birth Defects, Cleft Palate
Svangerskap, Arv, Og Miljo (Pregnancy, Heredity and Environment)
This proposal describes a population-based case-control study of all Norwegian infants born with cleft lip or palate over a five-year period. The study will be jointly supported by the U.S.
- Conditions
- Birth Defects, Cleft Palate, Cleft Lip
- Trial name
- NCT00340977
- Where
- 2 sites in Norway
- Volunteers
- 4,091 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Cleft Palate
Efficacy of Oral Versus Intravenous Acetaminophen for Primary Pediatric Cleft Palate Repair
The purpose of this investigator-initiated study is to determine whether acetaminophen is an effective pain reliever for primary cleft palate repair in children and possesses opioid sparing effects.
- Trial name
- NCT01500109
- Testing
- Oral acetaminophen, Ofirmev®, Opioid only
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Loma Linda University
Cleft Palate
The Use of Fibrin Sealant to Reduce Post Operative Pain in Cleft Palate Surgery
Cleft Palate is a condition which affects up to 1 in 500 live births. Current treatment is surgery to correct the underlying anomaly. Children born with cleft palate typically undergo surgery at age 12 months.
- Trial name
- NCT02953145
- Testing
- Tisseel
- Where
- Canada
- Sponsor
- University of Alberta
Receding Chin
Esthetic Outcome of Isolated Advancement Genioplasty With and Without Submental Liposuction in Treatment of Skeletal Chin Deficiency
This study is to measure the eshetic outcome of of isolated advancement genioplasty with and without submental liposuction in treatment of skeletal chin deficiency in double chin patients
- Trial name
- NCT04283708
- Testing
- Submental liposuction
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Cairo University