Clinical trials: Maxillofacial Deformity
Obstructive Sleep Apnea, Sleep Apnea, Obstructive
Orthognathic Surgery and Obstructive Sleep Apnea Assessed by Mandibular Jaw Movement Monitoring (SUNRISE-ORTHO)
Orthognathic surgery changes the skeletal framework of the upper airway, but its functional effect on sleep-disordered breathing remains poorly documented, particularly with respect to respiratory effort.
- Conditions
- Obstructive Sleep Apnea, Sleep Apnea, Obstructive, Dentofacial Deformities
- Trial name
- SUNRISE-ORTHO (NCT07910461)
- Testing
- Orthognathic surgery (BSSO with or without Le Fort I osteotomy), Sunrise mandibular jaw movement monitoring, Facial multidetector CT in natural head position
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- CHR Sambre et Meuse Site Meuse
Maxillofacial Abnormalities, Maxillofacial Injuries
Vitamin C Level Effect in Orthognathic Surgery
Comparing the pre and post-operative blood plasma levels of vitamin C according to oxidative stress and investigate the correlation between post-operative analgesia requirement and vitamin C levels following orthognathic surgery.
- Conditions
- Maxillofacial Abnormalities, Maxillofacial Injuries, Maxillofacial Trauma
- Trial name
- NCT04416386
- Testing
- Vitamin C
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Medipol University
Palatal Expansion Technique, Malocclusion
Comparison Between Two Rates of Activation of Miniscrew-Supported Upper Jaw Expander in Adolescents
Miniscrew-supported maxillary expanders provide advantages over conventional tooth-supported expanders. However, there is no consensus in the literature regarding their activation protocol.
- Conditions
- Palatal Expansion Technique, Malocclusion, Posterior Crossbite, Maxillary Hypoplasia
- Trial name
- NCT04225637
- Testing
- Miniscrew-Supported Maxillary Expander- Slow activation, Miniscrew-Supported Maxillary Expander- Rapid activation
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Facial Neoplasms, Head and Neck Neoplasms
Clinical Trial of New Elastomer for Maxillofacial Prosthetics
The purpose of this study is to evaluate a new rubber material used to make prosthetic replacements of the face lost to cancer, trauma, or birth defects.
- Conditions
- Facial Neoplasms, Head and Neck Neoplasms, Head Injuries, Penetrating, Birth Injuries
- Trial name
- NCT00123097
- Testing
- Chlorinated polyethylene elastomer
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Louisville
Three Dimensional, Dento-Skeletal
Three Dimensional Evaluation of Dento-Skeletal Effects of Leaf Self Expander in Cleft Lip and Palate Patients
This study aims to evaluate the dento-alveolar changes after maxillary expansion in cleft lip and palate patients by Leaf Self Expander, as compared to conventional Rapid Maxillary Expander using digital cast analysis and…
- Conditions
- Three Dimensional, Dento-Skeletal, Leaf Self Expander, Cleft Lip
- Trial name
- NCT07384338
- Testing
- Rapid maxillary expansion, Leaf Self Expander
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Maxillofacial Abnormalities
Maxillofacial Rehabilitation Using Motor Imagery vs Sham After Orthognathic Surgery
Dento-maxillary dysmorphoses are defined as an anomaly in the relative growth of the maxilla and/or mandible. They lead to functional disorders (i.e., disturbances in chewing or oral communication) and aesthetic issues with…
- Trial name
- MAXIMAND (NCT06263374)
- Testing
- Motor imagery of the jaw, Control task (Sudoku or Crossword puzzle)
- Where
- 3 sites in France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Mandibular Prognathism, Orthognathic Surgery
Evaluating the Accuracy of Soft Tissue Prediction in Patients With Mandibular Prognathism After Orthognathic Surgery Using Handheld Scanner Versus Optical Scanner A Prospective Clinical Trial
Aim of study: To evaluate the accuracy of soft tissue prediction in orthognathic surgery using handheld scanners versus optical scanners.
- Trial name
- NCT06724497
- Testing
- face scanning pre and post orthognathic surgery
- Where
- Egypt
- Volunteers
- 11 people
- Sponsor
- Cairo University
Maxillary Deficiency
Maxillary Sinus Augmentation Via the "Bone Lid Technique"
Maxillary sinus augmentation is one of the most performed procedures to increase the bone quantity of the atrophic maxilla in order to allow implant placement.
- Trial name
- SINUSLID_2023 (NCT06222970)
- Testing
- Bone lid repositioning in course of sinus lift
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pisa
Maxillofacial Injuries, Maxillofacial Trauma
Superficial Cervical Plexus Block for Orthognathic Surgery
US-guided superficial cervical plexus block (SCPB) may be used for several head and neck surgeries. Local anesthetic is injected under the sternocleidomastoid muscle for SCPB.
- Conditions
- Maxillofacial Injuries, Maxillofacial Trauma, Maxillofacial Abnormalities, Maxillofacial Dysostosis
- Trial name
- NCT04442009
- Testing
- Group SCPB
- Where
- Turkey (Türkiye)
- Sponsor
- Medipol University
Cleft Lip, Cleft Palate
Systematic Pediatric Care for Oral Clefts - South America
Cleft lip and palate are a significant component of morbid human birth defects in the developing world. This study measures the impact of having a child born with a cleft lip on subsequent maternal/infant family health, and…
- Conditions
- Cleft Lip, Cleft Palate, Congenital Defects
- Trial name
- NCT00097149
- Testing
- Systematic pediatric care
- Where
- Brazil
- Volunteers
- 696 people
- Sponsor
- NICHD Global Network for Women's and Children's Health
Cleft Lip and Cleft Palate, Cleft Lip Bilateral
Improving the Outcomes of Nasoalveolar Molding in Complete Bilateral Cleft Lip and Palate Neonates Using a Modification in the Design of the Conventional Molding Appliance.
The goal of this clinical trial was to improve the outcome of using the nasoalveoalr molding appliances in patients with complete bilateral cleft lip and palate.
- Conditions
- Cleft Lip and Cleft Palate, Cleft Lip Bilateral, Complete Bilateral Cleft Lip and Palate
- Trial name
- NCT07814625
- Testing
- vomer molding appliance, conventional molding appliance
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Tanta University
Cleft Palate
Dexmedetomidine vs Placebo for Pediatric Cleft Palate Repair
The primary objective of this study is to evaluate the efficacy of administering intravenous dexmedetomidine as a single preemptive dose to placebo in reducing the total 24 hour dose of opioids as measured on a weight adjusted…
- Trial name
- NCT02915042
- Testing
- Dexmedetomidine
- Volunteers
- healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Maxillary Hypoplasia, Cleft Lip Palate
Time and Type Dependent Evaluation of Different Techniques for Correction of Cleft Maxillary Hypoplasia
Maxillary hypoplasia in CLP deformities results from congenital reduction in midfacial growth and the effects of the surgical scar from CLP repair.Turvey et al.
- Conditions
- Maxillary Hypoplasia, Cleft Lip Palate, Orthognathic Surgery
- Trial name
- NCT06852196
- Testing
- orthognathic surgery ,lefort 1,bsso ,DO, distraction osteogenesis
- Volunteers
- 22 people
- Sponsor
- Assiut University
Schizophrenia, Micrognathia
The Relevance Between the microRNA-30e in Plasma and the Prognosis of Schizophrenia Patients
This study investigates the relationship of circulating microRNA-30e and schizophrenia, and shows the relevance of the aberrant microRNA-30e expression in plasma with the variation disease status.
- Trial name
- NCT03007303
- Testing
- Atypical Antipsychotic, atypical antipsychotic combined with MECT
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dalian Seventh People's Hospital
Palate, Cleft
Evaluation of Quality of Life After Orthognathic Surgery in a Cleft Lip and Palate Context
The purpose of this study is to compare, prospectively, the quality of life of patients with cleft lip and palate before and after orthognathic surgery.
- Trial name
- ORTHOQOL (NCT04049058)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Lille
Maxillofacial Abnormalities
Evaluation of the Long-term Results of Extended Supra-basillary Genioplasty of the "Chin Wing" Type Without Bone Graft
The correction of maxillomandibular dysmorphoses, responsible for both functional discomfort (lip incompetence, ventilation disorders, periodontal disease) but also aesthetic, calls in particular for genioplasty, of which there…
- Trial name
- SASCWatch (NCT06183853)
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Strasbourg, France
Orthognathic Surgical Procedures, Psychiatric Disorders
Incidence of Body Dysmorphic Disorder (BDD) in a Population of Patients Undergoing Orthognathic Surgery
Assessment of the incidence of Body dismorphic disorder in a population candidated to orthognathic surgery
- Conditions
- Orthognathic Surgical Procedures, Psychiatric Disorders, Prognathism
- Trial name
- IBDOS (NCT06879275)
- Testing
- Questionnaire and Physical Exam
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Venous Malformation
Complications of Ethanol-amine Oleate Intralesional Sclerotherapy
The aim of this study is to clarify complications of Ethanolamine Oleate intralesional injections of maxillofacial venous formations in pediatric patients
- Trial name
- NCT04930952
- Testing
- Ethanol-amine Oleate Sclerotherapy Injection
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Dentofacial Deformities
The Use of Bone-borne Guides in Orthognathic Surgery Cases
The present study was conducted to evaluate a new design of the intermediate stent that is used in orthognathic surgery cases requiring Le Fort I osteotomy.
- Trial name
- NCT04224805
- Testing
- Bone-borne CAD/CAM splint, 3D interocclusal conventional splint
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Cleft Palate
Cleft Palate With Intravelar Veloplasty Repair
Cleft palate repair is the most important component of cleft surgery, not only in that it determines the outcome as far as speech and communication are concerned, but also in that it potentially has the greatest impact on…
- Trial name
- NCT05196555
- Testing
- Repair of cleft palate with intravelar veloplasty (IVVP)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Hams Hamed Abdelrahman