Clinical trials: Meals
Diabetes Mellitus, Type 1 Diabetes
Medtronic Treat to Range (TTR) Closed-Loop Control
The purpose of this study is to evaluate a treat-to-range automated insulin management system using continuous glucose monitoring (CGM) and subcutaneous insulin pump infusion in individuals with type 1 diabetes.
- Conditions
- Diabetes Mellitus, Type 1 Diabetes, Metabolic and Nutritional Disorders
- Trial name
- NCT01490151
- Testing
- TTR controller (Medtronic)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Stanford University
Men With Mild Abdominal Obesity
Protein Bioavailability of Wolffia Globosa (Mankai); Acute Test Meal Effects
The investigators aim to test the protein bioavailability of new specific developed strain of duckweed [Wolffia globose, Mankai] , an aquatic plant, which might serve as a protein source and contains all the 9 essential and the 6…
- Trial name
- Mankai (NCT03020225)
- Testing
- White cheese, Green peas, Mankai
- Where
- Israel
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ben-Gurion University of the Negev
Obesity, Morbid, Obesity
Topiramate in Adolescents With Severe Obesity
The prevalence of severe pediatric obesity is on the rise and youth with this condition are at elevated risk for developing chronic diseases such as cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM).
- Conditions
- Obesity, Morbid, Obesity, Weight Loss
- Trial name
- NCT01859013
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Minnesota
Childhood Obesity
Obesity Prevention in Head Start
Family style dining is a widely-advocated approach by which to feed children in early education settings. While family-style dining is hypothesized to allow children to attend to their hunger and satiety and consume only the…
- Trial name
- NCT03672227
- Testing
- Mealtime Matters Training
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Type 2 Diabetes
Vildagliptin Versus Dapagliflozin on Glucagon
The aim of the study is to assess if vildagliptin and dapagliflozin have dissociated effects on glucagon secretion after a mixed meal ingestion in metformin-treated subjects with type 2 diabetes and whether this is associated…
- Trial name
- NCT02475070
- Testing
- Vildagliptin, Dapagliflozin
- Where
- Sweden
- Volunteers
- 28 people
- Sponsor
- Lund University
Feeding Behavior
Variations in Palatability and Portion Size of Vegetables on Meal Intake of Preschool Children
The aim of the study is to determine the effect of varying both the palatability and portion size of vegetables served to preschool children at a meal on the outcomes of food and energy intake at the meal.
- Trial name
- NCT03926065
- Testing
- Plain Vegetables Served in 100% Portion Size, Plain Vegetables Served in 200% Portion Size, Enhanced Vegetables Served in 100% Portion Size
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Penn State University
Hypertension
Efficacy and Safety of Aliskiren 75 mg, 150 mg, and 300 mg in Elderly Patients With Essential Hypertension When Given With a Light Meal in a 8 Week Placebo-controlled Study
This study will evaluate the efficacy and safety of aliskiren 75 mg, 150 mg, and 300 mg in elderly patients with essential hypertension when given with a light meal.
- Trial name
- NCT00706134
- Testing
- Aliskiren 75 mg, Aliskiren 150 mg, Aliskiren 300 mg
- Where
- 8 sites in Argentina, Czechia and 6 more
- Volunteers
- 756 people
- Sponsor
- Novartis
Type 1 Diabetes
Extended Bolus for Meals in a Closed-loop System
This study aims to evaluate whether the use of an extended bolus will improve glucose control with high-fat high protein meals using a closed-loop system.
- Trial name
- NCT05454891
- Testing
- Tandem t:slim X2 insulin pump: Extended bolus of insulin then standard bolus of insulin, Tandem t:slim X2 insulin pump: Standard bolus of insulin then extended bolus of insulin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Heartburn
Proof of Concept Study Efficacy of an Antacid/Lansoprazole Combination for Relief of Heartburn
This study will investigate the safety and efficacy of an antacid/Lansoprazole combination product for the relief of heartburn after consuming a heartburn-inducing meal.
- Trial name
- NCT01037452
- Testing
- Calcium carbonate/magnesium hydroxide/Lansoprazole 15 mg, Lansoprazole, Calcium carbonate/magnesium hydroxide
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Novartis
Effects of Different Meals on the QT/QTc Interval, Insulin and Oral Hypoglycemic [Antidiabetic] Drugs Causing Adverse Effects in Therapeutic Use
Food and Insulin Effect on QT/QTC Interval of ECG
Moxifloxacin is routinely used as a probe to confirm assay sensitivity in thorough electrocardiogram (ECG) studies. It has been shown that a meal shortens the QT interval, which may affect pharmacokinetics (PK) and/or…
- Conditions
- Effects of Different Meals on the QT/QTc Interval, Insulin and Oral Hypoglycemic [Antidiabetic] Drugs Causing Adverse Effects in Therapeutic Use, C-Peptide Effects on the QT/QTc Interval, Moxifloxacin ECG Profile in Fed and Fasted State
- Trial name
- C11035 (NCT01642485)
- Testing
- Moxifloxacin 400 mg fasted, FDA breakfast, Continental breakfast
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Richmond Pharmacology Limited
Healthy
Fed Bioequivalence Study of Fenofibric Acid Versus TriCor® (Fenofibrate)
This study will evaluate the bioequivalence of 105 mg fenofibric acid tablets relative to 145 mg fenofibrate tablets in healthy volunteers when administered following a breakfast of standard composition.
- Trial name
- NCT00960687
- Testing
- Fenofibric Acid (Fibricor™) 105 mg Tablet, Fenofibrate (Tricor®) 145 mg Tablet
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Mutual Pharmaceutical Company, Inc.
Malnutrition
COPD: Oral Nutrition Supplements vs. Energy- and Protein Dense in Between Meal Snacks.
At least one fifth of patients in European hospitals are malnourished. Malnutrition is associated with negative consequences, including higher rates of complications, longer hospital stay, impaired wound healing and increased…
- Trial name
- COPD (NCT02251496)
- Testing
- In between meals snacks (Snacks-group), Oral nutrition supplement (ONS-group)
- Where
- Iceland
- Volunteers
- 34 people
- Sponsor
- University of Iceland
Hypogonadism
The Effect of Various Amounts of Fat on PK of Oral Testosterone Undecanoate
A Phase 2, open-label, randomized, cross-over, pharmacokinetic study designed to determine the effect of meals of various amounts of fat given immediately prior to dosing on the pharmacokinetics of oral testosterone undecanoate.
- Trial name
- NCT02921386
- Testing
- Oral Testosterone Undecanoate
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Clarus Therapeutics, Inc.
Asthma in Children, Pollution; Exposure
AIM to Improve Asthma: Airflow Improvements During Meal-Prep
The investigators propose a pilot trial of kitchen ventilation in the homes of children using a youth engaged research strategy.
- Trial name
- AIM (NCT04464720)
- Testing
- Cooking Ventilation Intervention
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of California, Berkeley
Food Selection
Climate Impact Label Design and Fast-Food Meal Selection
The primary objective of this study is to test the relative effects of climate-impact menu label designs on the healthfulness of consumers' fast-food meal choices.
- Trial name
- NCT06678178
- Testing
- Control (QR) Labels, Warning High Climate Impact Labels, Traffic Light Labels
- Where
- United States
- Volunteers
- 6,622 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Diabetes, Diabetes Mellitus, Type 2
Comparison of Insulin Detemir, Insulin Aspart and Biphasic Insulin Aspart 30 With OAD Treatment in Type 2 Diabetes
This trial is conducted in Europe. The aim of this research study is to compare the efficacy (reduction in HbA1c and in blood glucose levels) of insulin detemir, insulin aspart and biphasic insulin aspart 30, when added to…
- Trial name
- 4T (NCT00184600)
- Testing
- biphasic insulin aspart, insulin detemir, insulin aspart
- Where
- 63 sites in Ireland, United Kingdom
- Volunteers
- 708 people
- Sponsor
- Novo Nordisk A/S
Overweight, Obese
The Effect of Protein-enriched Diet on Body Composition and Appetite
Obesity is a major problem worldwide and current dietary interventions are not proving to be enough to cease the increase in levels of obesity and its detrimental side effects, such as nonalcoholic fatty liver disease (NAFLD).
- Conditions
- Overweight, Obese, Metabolic Syndrome, Non Alcoholic Fatty Liver Disease
- Trial name
- ProteinRich (NCT01634048)
- Testing
- High Protein, low calorie meal replacement
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Pediatric Obesity, Insulin Resistance
High-fat Meal Challenge in Pediatrics
The objective is to determine if how physical fitness, measured using a treadmill maximal oxidative capacity test, is associated with the capacity to metabolize a high-fat meal in pediatrics (ages 8-17 years).
- Trial name
- NCT05230433
- Testing
- High-fat Challenge
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Diabetes Mellitus, Type 1
A Meal Test Study of LY900014 in Participants With Type 1 Diabetes Mellitus
Two forms of insulin lispro (LY900014 and Humalog®) and two forms of insulin aspart (NovoRapid® and Fiasp®) will be given to trial participants with diabetes mellitus type 1 by injection under the skin.
- Trial name
- NCT03449433
- Testing
- LY900014, Insulin Lispro, Insulin Aspart
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Cardiovascular Diseases
Brazilian Heart-Prevent Meal - A Pilot Randomized Clinical Trial
The purpose of this study is to evaluate the effectiveness of a brazilian cardioprotective diet plan to reduce cardiovascular risk factors of new cardiovascular events.
- Trial name
- NCT01453166
- Testing
- Brazilian heart-prevent meal, Heart prevent control meal weekly, Heart prevent control Meal monthly
- Where
- Brazil
- Volunteers
- 122 people
- Sponsor
- Hospital do Coracao