Clinical trials: Mean Arterial Pressure
Healthy
Validation Study of Mean Arterial Pressure (MAP) Parameter of Masimo INVSENSOR00073
The aim of the study is to validate the Mean Arterial Pressure (MAP) parameter of Masimo INVSENSOR00073 against the gold standard blood pressure measurements from the arterial line while subject undergo a blood pressure variation…
- Trial name
- NCT06334055
- Testing
- Masimo INVSENSOR00073
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Hypertension, Hypertension, Systolic
Treatment of Hypertension During Sleep
On the basis of new evidence on the relationship between achieved office blood pressure (BP) measurements (OBPM) and the risk of cardiovascular disease (CVD) morbidity and mortality documented in the SPRINT trial, the recent 2017…
- Trial name
- THADEUS (NCT03457168)
- Testing
- Treatment of elevated asleep SBP mean
- Where
- 9 sites in Spain
- Volunteers
- 5,320 people
- Sponsor
- University of Vigo
Cardiovascular Diseases
Closed-loop Control Mean Arterial Pressure In Intensive Care Patients
The purpose of this case series is to evaluate the performance of a novel closed-loop (automated) vasopressor administration system that delivers norepinephrine using feedback from standard hemodynamic monitor (EV1000 Monitor)…
- Trial name
- NCT04357197
- Testing
- Closed-loop
- Sponsor
- Erasme University Hospital
Coronary Artery Disease, Postoperative Complications
Intraoperative Targeted Versus Liberal Blood Pressure Management in Patients Undergoing Off-pump Coronary Artery Bypass Grafting
The goal of this clinical trial is to learn whether two approaches to anesthesia and blood pressure management can improve care for adults having off-pump coronary artery bypass grafting (OPCAB).
- Trial name
- NCT07787364
- Testing
- Targeted Blood Pressure Management, Liberal Blood Pressure Management, Remimazolam
- Volunteers
- 416 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Respiratory Failure, Hypotension and Shock
Using Vasopressor Medication to Support Blood Pressure During Intubation Procedure
The purpose of this study is to investigate whether protocolized vasopressor use for patients with normal blood pressure undergoing rapid sequence intubation improves hemodynamic parameters and mitigates adverse events.
- Conditions
- Respiratory Failure, Hypotension and Shock, Hypotension on Induction, Intubation Complication
- Trial name
- RAPID PRESS (NCT05355974)
- Testing
- Norepinephrine, Lactated Ringers, Intravenous, normal saline
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Wright State University
Hypotension on Induction, Cardiac Surgery
The Impact of Multiple Antihypertensive Therapy on Post-Induction Hypotension Burden in Cardiac Surgery Patients
This study aims to investigate the impact of multiple preoperative antihyperstensive drug use on the burden of post-induction hypotension (PIH) in patients undergoing elective cardiac surgery.
- Conditions
- Hypotension on Induction, Cardiac Surgery, Antihypertensive Agents, Anesthesia, Intravenous
- Trial name
- NCT07541222
- Testing
- Chronic Antihypertensive Medication Use
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Konya City Hospital
Low Bispectral Index, Low Mean Arterial Blood Pressure
Randomized Trial of Alerts in Patients Demonstrating a "Triple Low"
The investigators propose to test the theory that smart alarms for the Triple Low State incorporated into a decision support system built into an electronic anesthesia record will prompt clinicians to intervene earlier in…
- Conditions
- Low Bispectral Index, Low Mean Arterial Blood Pressure, Low End-tidal Anesthetic Concentration
- Trial name
- NCT00998894
- Where
- United States
- Volunteers
- 9,846 people
- Sponsor
- The Cleveland Clinic
Anterior Cerebral Artery Syndrome, Anterior Cerebral Artery Stroke
Transcranial Doppler Evaluation After Endovascular Thrombectomy for Acute Ischemic Stroke (PRECISE-TCD)
Endovascular thrombectomy (EVT) improves outcomes in acute ischemic stroke caused by large vessel occlusion. Despite successful recanalization, early neurological deterioration (END) remains frequent and is associated with poor…
- Conditions
- Anterior Cerebral Artery Syndrome, Anterior Cerebral Artery Stroke, Acute Ischemic Stroke, Cardioembolic Stroke
- Trial name
- NCT07013396
- Testing
- Transcranial Doppler (TCD) examination
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Virginia Commonwealth University
Heart; Surgery, Heart, Functional Disturbance as Result
Trial to Compare Different Strategies of Mean Arterial Pressure Management During Cardiopulmonary By-pass
Background: One of the main goals of the Cardiopulmonary By-Pass (CPB) is targeting an adequate Mean Arterial Pressure (MAP), in order to maintain appropriate perfusion pressures in all end-organs during heart surgery.
- Trial name
- MAP (NCT05740397)
- Testing
- Management of mean arterial pressure during cardiopulmonary by-pass in cardiac surgery interventions. The MAP will be mantained in the range of values of each study arm
- Where
- Italy
- Volunteers
- 900 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Arterial Hypotension
Dopamine Versus Dobutamine for Treatment of Arterial Hypotension in Term and Preterm Neonates
The purpose of this study is to examine the effects of Dobutamine as compared to Dopamine in term and preterm neonates with arterial hypotension on cerebral and renal oxygenation, fractional tissue oxygen extraction, mean…
- Trial name
- NCT01427686
- Testing
- Dobutamine, Dopamine
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Ulm
Intubation, Nociceptive Pain
NoL, HR and MABP Responses to Tracheal Intubation Performed With MAC Blade Versus Glidescope
Prospective, randomized and controlled who will be conducted in Maisonneuve-Rosemont hospital and whose objectives are: To observe if the alterations of the NoL index and the standard monitoring (Mean Arterial Blood Pressure and…
- Conditions
- Intubation, Nociceptive Pain, Anesthesia, Laryngoscopy
- Trial name
- NoLint (NCT03277872)
- Testing
- Laryngoscopy with GlideScope (GVL) Blade, Laryngoscopy with MacIntosh (MAC) Blade
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Health, Subjective
Effects of Blood Flow Restriction Training on Exercises in Healthy Individuals.
Partial restriction of blood flow to working muscles during exercise is proven to increase muscle mass and strength even with low-intensity of exercise.
- Trial name
- NCT06254586
- Testing
- Aerobic exercises, Resisted exercises
- Where
- Saudi Arabia
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Prince Sattam Bin Abdulaziz University
Septic Shock, Acute Kidney Injury
Personalized Mean Arterial Pressure Management on Renal Function During Septic Shock
Sepsis is the most severe complication of infections. Sepsis-associated Acute kidney injury (AKI) is commonly encountered in critically ill patients and independently predicts poor outcome.
- Trial name
- DORESEP (NCT01473498)
- Testing
- Haemodynamic management
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Secondary Peritonitis, Post-induction Hypotension
Low-dose Norepinephrine Infusion for Prevention of Post-induction Hypotension in Emergency Surgery for Peritonitis
This study tests whether giving a low-dose norepinephrine infusion just before induction of anesthesia can reduce low blood pressure during emergency surgery for peritonitis.
- Trial name
- NCT07529795
- Testing
- Norepinephrine (0.05 μg/kg/min)
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Bach Mai Hospital
Septic Shock, Vasodilatory Shock
Vasopressin Use in Septic Shock From Türkiye
The goal of this observational study is to examine the early hemodynamic effects and clinical outcomes of vasopressin use in patients with septic shock.
- Conditions
- Septic Shock, Vasodilatory Shock, Critical Illness Sepsis, Severe, Critical Illness
- Trial name
- (VASCO-TURK) (NCT06953297)
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people
- Sponsor
- Karadeniz Technical University
Blood Pressure
Performance Measurement in Cardiac Surgery
This study aimed to evaluate the relationship between the perioperative blood pressure and postoperative mortality after cardiac surgery using performance measurement (PM) of mean arterial pressure (MAP).
- Trial name
- NCT03785132
- Testing
- Cardiac surgery
- Where
- South Korea
- Volunteers
- 1,300 people
- Sponsor
- Seoul National University Hospital
Head Trauma, Traumatic Coma
The Effect of Auditory and Tactile Stimuli in Traumatic Coma
This study focused on examining the effects of auditory and tactile stimuli to reduce sensory deprivation on consciousness, oxygen saturation and mean arterial pressure in traumatic coma patients.
- Conditions
- Head Trauma, Traumatic Coma, Nursing Caries
- Trial name
- NCT05195606
- Testing
- Auditory stimulus, Tactile stimulus
- Volunteers
- 90 people
- Sponsor
- Akdeniz University
Hypotension During Surgery, NGAL
Controlled Hypotension and Renal Injury During Septoplasty
This prospective randomized single-blind study investigated the effects of two different mean arterial pressure (MAP) targets during controlled hypotension on renal injury in patients undergoing septoplasty.
- Conditions
- Hypotension During Surgery, NGAL, Kidney Injury
- Trial name
- NCT07662577
- Testing
- Controlled Hypotension (MAP 50-57 mmHg), Controlled Hypotension (MAP 58-65 mmHg)
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Mitral Insufficiency, Mitraclip
Hemodynamic Estimation of the Result of the MitraClip Technique: Interest of the Ratio of Mean Arterial Pressure (MAP) to Pressure of the Mean Left Atrium (POG) (MitraPOG)
this research is based on the hypothesis that the measurement of the ratio of mean arterial pressure to mean left atrium pressure and of its evolution during the procedure, would make it possible to assess the immediate success…
- Trial name
- MitraPOG (NCT05123430)
- Testing
- Monitoring of the pressure of the middle left atrium
- Where
- France
- Volunteers
- 30 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Type 2 Diabetes Mellitus, Hypertension
Empagliflozin Versus Non-SGLT2 Oral Drugs for Blood Pressure in Type 2 Diabetes
This randomized controlled trial studied whether empagliflozin lowers blood pressure better than non-SGLT2 oral hypoglycemic treatment in adults with type 2 diabetes mellitus and hypertension.
- Trial name
- EMPA-BP (NCT07541456)
- Testing
- Empagliflozin, Metformin
- Where
- Pakistan
- Volunteers
- 300 people
- Sponsor
- Dr. Zarmina Younes