Clinical trials: Measure Development
Infertility
2D Versus SonoAVC Scanning in High Responders
Accurate follicular monitoring of Controlled Ovarian Stimulation by transvaginal ultrasound is considered important for the success of human in vitro fertilization (IVF).
- Trial name
- NCT03610009
- Testing
- 2D ultrasound, SonoAVC
- Where
- Greece
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Eugonia
Urinary Incontinence, Urinary Retention
Codesign of an Optical Device to Measure Urine Flow and Volume
The study is seeking to understand the needs of patients and healthcare practitioners for an innovation in the way that changes in bladder function are assessed.
- Conditions
- Urinary Incontinence, Urinary Retention, Urinary Tract Infections, Overactive Bladder
- Trial name
- NCT05576311
- Testing
- Focus Group
- Volunteers
- 45 people
- Sponsor
- Teesside University
Crohns Disease
Development of a Novel Endoscopic Index and Patient-reported Outcome Measure for Clinical Trials in Participants With Permanent Ileostomy
To date, patients with Crohn's Disease (CD) and permanent ileostomies have been excluded from clinical trials for new treatments.
- Trial name
- NCT06670638
- Where
- 5 sites in United States, Canada
- Volunteers
- 50 people
- Sponsor
- Alimentiv Inc.
Achilles Tendon Rupture
The Achilles Tendon Length Measure (ATLM) - Development and Validation
The purpose of this study is 1) to develop and validate a new measurement to assess the length of the Achilles tendon after rupture, and 2) to examine if goniometer measurement of the ankle joint is a better method.
- Trial name
- NCT02044016
- Where
- Denmark
- Volunteers
- 28 people
- Sponsor
- Hvidovre University Hospital
Congestive Heart Failure
BNP Measurement Reduces Resource Utilization for Patients With CHF Admitted Thorough the ED
Measurement of brain natriuretic peptide (BNP) in dyspneic patients increases diagnostic accuracy for congestive heart failure (CHF). Limited information is available regarding economic outcomes attributable to BNP assay.
- Trial name
- NCT00587938
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
HIV/AIDS
The I-Score Study: Developing a New Patient-Reported Tool for the Routine HIV Care of Patients on Antiretroviral Therapy
The purpose of this Canada-France study is to develop and validate a multidimensional patient-reported measure of perceived barriers to antiretroviral therapy adherence for HIV-positive patients undergoing treatment that will be…
- Trial name
- NCT02586584
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- Dr. Bertrand Lebouche
Nursing Education, Vital Signs
Game-Based 3D Simulation for Vital Signs Training in Nursing Education
This study aims to improve nursing students' skills in measuring vital signs using a 3D animation-based game simulation. Measuring vital signs is a key responsibility for nurses and requires both knowledge and hands-on practice.
- Conditions
- Nursing Education, Vital Signs, Animation, Academic Acheivement
- Trial name
- NCT07009275
- Testing
- The game-based simulation application developed using 3D animation technology
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Type 2 Diabetes
Study Enabling the Collection of Clinical Data Necessary for the Second Phase of Development of the Glycemic Measurement Device by Analysis of Exhaled Air
A pilot study carried out by the company ALPHA-MOS in 2017-19 showed that the analysis of volatile organic compounds contained in exhaled air could reliably predict blood glucose levels.
- Trial name
- BOYDSENSE DATA (NCT06614101)
- Testing
- Exhaled air analysis
- Where
- 2 sites in France
- Volunteers
- 235 people
- Sponsor
- University Hospital, Toulouse
Cardiovascular, Psychological Stress
Effects of Antioxidants on Cardiovascular Risk Measures (Spice Study)
The purpose of this study is to assess whether feeding highly antioxidant spices of providing these same antioxidants as capsules is able to affect cardiovascular risk measures.
- Trial name
- Spice (NCT00954902)
- Testing
- High Antioxidant Spice Blend, Trier Psychological Stressor
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Penn State University
Healthy Participants
Development of Novel Measures for Alzheimer's Disease Prevention Trials
This protocol focuses on novel measures of cognition and everyday function that have robust psychometrics and reduced practiced effects.
- Trial name
- NoMAD (NCT03900273)
- Testing
- No Practice Effects (NPE) cognitive battery, and Miami Computerized Functional Assessment Scale (CFAS), Preclinical Alzheimer's Cognitive Composite (PACC), Alzheimer's Disease Assessment Scale-Cognitive Scale (ADAS-Cog), and Functional Assessment Questionnaire (FAQ)
- Where
- 4 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Coronary Artery Disease
Development and Validation of a Scale to Measure Fear of ACTivity in Patients With Coronary Artery Disease
Low motivation to exercise is one of the barriers to participation in cardiac rehabilitation. Fear of activity after a cardiac event is associated with low levels of physical activity.
- Trial name
- Fact-CAD (NCT03858829)
- Testing
- Psychometric analysis
- Volunteers
- 250 people
- Sponsor
- Hitit University
Rhinitis, Nasal Polyps
Development and Validity of the DyNaChron Questionnaire for Chronic Nasal Dysfunction
Nasal symptoms are the main elements that lead to a therapeutic decision and allow for evaluating treatment effects or natural evolution.
- Trial name
- DyNaChron (NCT02879929)
- Volunteers
- 759 people
- Sponsor
- Central Hospital, Nancy, France
Opioid Craving, Opioid Use Disorder
Developing a Clinical Outcome Assessment for Opioid Craving
The purpose of this study is to collect information about opioid craving so that the investigators can develop an opioid craving assessment to improve treatments for individuals with opioid use disorder.
- Conditions
- Opioid Craving, Opioid Use Disorder, Measure Development
- Trial name
- NCT05109429
- Testing
- Neutral Cue-induced Craving, Visual Opioid Cue-induced Craving, Visual and Tactile Opioid Cue-induced Craving
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Coronary Heart Disease
Pharmaceutical Follow-up of Coronary Heart Disease (CHD) Patients
Objectives To explore the impact of a clinical pharmacist-led 12 month lasting follow-up program for patients with established coronary heart disease (CHD) discharged from the North Norway University Hospital.
- Trial name
- NCT01115608
- Testing
- Pharmacist follow-up
- Where
- Norway
- Volunteers
- 102 people
- Sponsor
- Hospital Pharmacy of North Norway Trust
Hereditary Hemorrhagic Telangiectasia
Development of a Quality of Life Measurement Scale in Hereditary Haemorrhagic Telangiectasia (HHT) Disease.
Hereditary Haemorrhagic Telangiectasia (HHT) is a rare inherited genetic disease of autosomal dominant inheritance with a prevalence of 1/6000.
- Trial name
- ELECT-RO (NCT03695874)
- Testing
- Phase 1 : fill out 1 scale, Phase 2 : fill out 1 scale and 4 questionnaires
- Where
- France
- Volunteers
- 643 people
- Sponsor
- Hospices Civils de Lyon
Klinefelter Syndrome, Diabetes
Body Composition, Bone Mineral Density, Insulin Sensitivity and Echocardiographic Measurements in Klinefelter Syndrome
Klinefelter syndrome (KS) is the most common sex-chromosome disorder with a prevalence of one in 660 men and is a frequent cause of hypogonadism and infertility.
- Conditions
- Klinefelter Syndrome, Diabetes, Osteoporosis, Metabolic Syndrome
- Trial name
- NCT00523835
- Where
- Denmark
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Syringomyelia, Chiari Malformation
Development of a Patient-reported Outcome Measure for Chiari Malformation and Syringomyelia
Chiari malformation corresponds to the herniation of cerebellar tonsils into the foramen magnum resulting in obstruction of cerebrospinal fluid circulation, which may eventually lead to the formation of an intramedullary cavity…
- Trial name
- BCS-score (NCT06011226)
- Testing
- focus groups, questionnaire
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Neurofibromatosis Type 1, Neurofibroma
Development of Patient-Reported Outcome Measures Assessing Tumor Visibility and Appearance Concerns in Neurofibromatosis Type 1: A Qualitative Study
Background: Neurofibromatosis 1 (NF1) is a disease that causes tumors to grow along the nerves. These include plexiform neurofibromas (pNF) and cutaneous neurofibromas (cNF). Both pNF and cNF can be visible to other people.
- Trial name
- NCT06880991
- Testing
- Arm 1
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- National Cancer Institute (NCI)
Lung Transplantation
Development a Method to Extract Antibiotic Concentration From Interstitial Lung and Epithelial Lining Fluid.
Infections are critical factors for the survival of critically ill patients. A serious problem is the high variability of antibiotic concentrations in critically ill patients.
- Trial name
- ALF (NCT03970265)
- Testing
- extraction of ELF and ILF from explanted lung tissue; meropenem concentration in ELF and ILF; ELF on postoperative day 1-5 when bronchoscopy is performed within clinical routine.
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Behçet Disease, Behcet's Disease Aggravated
Behçet's Disease Overall Damage Index
Damage in vasculitis, as well as in other chronic inflammatory disorders, accrues over time resulting in impairment of quality of life, development of disability and increased mortality.
- Trial name
- BODI (NCT03803462)
- Testing
- Behçet's disease Overall Damage Index (BODI)
- Where
- 10 sites in Greece, Italy and 3 more
- Volunteers
- 210 people
- Sponsor
- University of Cagliari