Clinical trials: Mechanical Circulatory Support
Cardiogenic Shock Acute, Acute Myocardial Infarction
Danish Cardiogenic Shock Trial
Cardiogenic shock a serious complication of a heart attack (myocardial infarction). Despite rapid invasive treatment, circulatory support using positive inotropes and mechanical support with intra-aortic balloon counterpulsation…
- Trial name
- DanShock (NCT01633502)
- Testing
- Conventional circulatory support, Impella CP
- Where
- 13 sites in Denmark, Germany and 1 more
- Volunteers
- 360 people
- Sponsor
- Odense University Hospital
Cardiogenic Shock Acute, Cardiogenic Shock
Cardiovascular Outcomes Registry in Cardiogenic SHOCK (COR-SHOCK)
The goal of this observational study is to evaluate the clinical outcomes and management approaches of cardiogenic shock throughout the years in adult patients admitted to a Cardiology Department.
- Conditions
- Cardiogenic Shock Acute, Cardiogenic Shock, Cardiogenic Shock Post Myocardial Infarction
- Trial name
- COR-SHOCK (NCT07597291)
- Where
- Portugal
- Volunteers
- 800 people
- Sponsor
- Hospital de Santa Cruz, Portugal
Mechanical Circulatory Support
Cerebral Oximetry, Pulmonary Artery Catheter Parameters and ECMO Flow in Patients Supported With Veno-arterial ECMO
for patients connected to VA ECMO due to cardiogenic shock, monitoring: 1. Cerebral Oximetry 2. ECMO Parameters ECMO blood flow (L/min) every 12 hours. Sweep gas flow Cannulation configuration 3.
- Trial name
- ECMO (NCT07526181)
- Volunteers
- 30 people
- Sponsor
- Assiut University
Heart Failure, Cardiovascular Diseases
Anti-thrombotic Monotherapy in HeartMate 3 Left Ventricular Assist System (LVAS)
The purpose of this prospective controlled study is to obtain a multi-center safety and feasibility data on patients managed with anti-thrombotic monotherapy with HeartMate 3 LVAS.
- Trial name
- NCT03781258
- Testing
- Warfarin
- Where
- Czechia
- Volunteers
- 20 people
- Sponsor
- Institute for Clinical and Experimental Medicine
End-stage Heart Failure, Cardiomyopathies
Noninvasive Cardiovascular Diagnosis of Patients With Fully Magnetically Levitated Blood Pumps
Left Ventricular Assist Device (LVAD) therapy has become a well-established treatment option for endstage heart-failure either as a bridge to transplant (BTT) or destination therapy (DT).
- Conditions
- End-stage Heart Failure, Cardiomyopathies, Mechanical Circulatory Support
- Trial name
- HM3_Snoopy (NCT04641416)
- Testing
- Routinely performed echo, ECG and hemodynamic monitoring
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Thomas Schlöglhofer, PhD, MSc
Heart Failure, Acute Decompensated Heart Failure
Feasibility Study to Support Cardiorenal Function in Acute Decompensated Heart Failure With Diuretic Resistance
Evaluation of the safety and efficacy of the ModulHeart System in patients hospitalized with acute decompensated heart failure (ADHF) and diuretic resistance
- Conditions
- Heart Failure, Acute Decompensated Heart Failure, Cardiorenal Syndrome, Heart Failure, Congestive
- Trial name
- NCT06174623
- Testing
- ModulHeart Support
- Where
- 5 sites in Australia, Georgia
- Volunteers
- 5 people
- Sponsor
- Puzzle Medical Devices Inc.
Heart Failure, Systolic, Mechanical Circulatory Support
Cardiac Output in Heart Failure Patients With Mechanical Pumps
This study will be looking at how cardiovascular hemodynamics, including cardiac output and flow through a left ventricular assist device (LVADs), change in response to alterations in preload, afterload, and contractility, and…
- Conditions
- Heart Failure, Systolic, Mechanical Circulatory Support, Cardiovascular Hemodynamics
- Trial name
- NCT05195931
- Testing
- preload challenge, afterload challenge, contractility assessment
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Colorado, Denver
Heart Failure, Mechanical Circulatory Support
Cell Therapy and Myocardial Recovery in Heart Failure Patients Undergoing Left Ventricular Assist Device Support
The goal of CELL-VAD Pilot trial is to investigate a personalized stem cell therapy approach for patients with advanced non-ischemic chronic heart failure (NICM) who are supported by LVAD.
- Trial name
- CELL-VAD (NCT06154044)
- Testing
- CD34+ stem cell therapy
- Where
- Slovenia
- Volunteers
- 10 people
- Sponsor
- University Medical Centre Ljubljana
Cardiogenic Shock Acute, Bypass, Cardiopulmonary
Prognosis of Patients With Mixed Cardiogenic-Vasoplegic Shock
Mixed cardiogenic-vasoplegic shock (M-CS) represents a distinct and severe phenotype of cardiogenic shock characterized by concomitant myocardial dysfunction and inappropriate systemic vasodilation.
- Conditions
- Cardiogenic Shock Acute, Bypass, Cardiopulmonary, Septic Shock, Mechanical Circulatory Support
- Trial name
- PROMIX (NCT07354568)
- Where
- France
- Volunteers
- 2,500 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens