Clinical trials: Mechanical Stress
Respiratory Failure
Comparison of the Efficacy for Stress Ulcer Prophylaxis Between the Patients Received Lansoprazole OD and Control Group Weaning From Mechanical Ventilator in Respiratory Care Center: a Randomized Control Trial
The purpose of this study is to determine whether lansoprazole administered nasogastrically is effective for stress ulcer prophylaxis in respiratory intensive care unit.
- Trial name
- NCT00708149
- Testing
- lansoprazole OD
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Far Eastern Memorial Hospital
Surgery, Critical Illness
Sedation Optimisation Strategy (S.O.S.) Ventilation
Use of sedatives and analgesics is common in mechanically ventilated patients hospitalized in Intensive Care Unit (ICU). That is called " sedation " and aimed to reduce both pain and anxiety and also to allow an effective and…
- Conditions
- Surgery, Critical Illness, Mechanical Ventilation Complication, Organ Dysfunction Syndrome
- Trial name
- NCT01486121
- Testing
- Therapy strategy
- Where
- 3 sites in France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Montpellier
Superior Limbic Keratoconjunctivitis, Dry Eye Syndromes
Diadenosine Polyphosphates and Mucin Associated With Ocular Surface Disorders
Dry eye disease, ocular graft-versus-host disease (GVHD), and superior limbic keratoconjunctivitis (SLK) are all ocular surface disorders which mostly involve the outer surface of the eye.
- Conditions
- Superior Limbic Keratoconjunctivitis, Dry Eye Syndromes, Graft Vs Host Disease
- Trial name
- NCT03731624
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Prematurity, Mechanical Ventilation
The Effect of Breast Milk Odor and Swaddling on Physiological Parameters and Stress Levels in Premature Infants Receiving Ventilator Support
It will be done to shorten the hospital stay of the newborn and increase the quality of care by proving the positive effect of the safe wrapping method and the smell of breast milk on the physiological parameters and stress level…
- Trial name
- NCT07681934
- Testing
- Breast Milk Smell, Arson, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- KTO Karatay University
Critical Illness
Cortisol Levels as a Measure of Accumulated Physiological Stress in ICU Patients Undergoing Mechanical Ventilation
Critical illness is a situation of severe and prolonged stress for patients with mechanical ventilation (MV). Between 40-80% of these patients present the Post-ICU syndrome, a set of physical, cognitive, psychological alterations…
- Trial name
- Corti-COG (NCT03736135)
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- Corporacion Parc Tauli
Nasal Injury
The Effect of Hydrocolloid Tape and Facial Massage in Premature Infants During Noninvasive Mechanical Ventilation
The aim of this study is to assess the effect of nasal injury prevention interventions (NIPI) (hydrocolloid tape and facial massage) on nasal septum injury, stress and comfort of premature neonates (28-35 weeks gestation)…
- Trial name
- NIPI (NCT05844345)
- Testing
- Hydrocolloid barrier group, Facial Massage group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ordu University
Stress (Psychology)
Effects of Mechanical Massage on Sleep Quality, Immunity, and Stress
This bicentric, randomized, single-blind clinical investigation aims to evaluate the effects of a multisession mechanical massage (endermologie) program on sleep quality, immune function, and stress levels in individuals…
- Trial name
- NCT07811284
- Testing
- Mechanized Massage (LPG Cellu M6 Alliance)
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bescored
Critical Illness
Music Listening: A Mechanistic Trial
A randomized within-subject crossover trial to compare the effects of live and recorded music listening on biomarkers of stress and pain among children receiving mechanical ventilation in the pediatric intensive care unit.
- Trial name
- NCT05541029
- Testing
- Live music, Recorded music, Usual care
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- University of Pittsburgh
Stress Urinary Incontinence, Urge Urinary Incontinence
Transcutaneous Mechanical Nerve Stimulation in the Treatment of Incontinence
During transcutaneous mechanical nerve stimulation in spinal cord injured men an increase in pressure was observed in the external urethral sphincter along with an increase in bladder capacity.
- Trial name
- NCT01366066
- Testing
- Transcutaneous mechanical nerve stimulation
- Where
- Denmark
- Volunteers
- 4 people
- Sponsor
- Copenhagen University Hospital at Herlev
Acute Respiratory Failure, Shock
Psychological Trauma and Resilience After Critical Illness
Critically ill patients experience a severe physical disease, associated with a psychotrauma, which may lead to post-traumatic stress disorder (17 to 30% of patients after critical illness) and persistent symptoms of anxiety and…
- Trial name
- RESIREA (NCT05193123)
- Where
- 23 sites in France
- Volunteers
- 200 people
- Sponsor
- Nantes University Hospital
Diaphragm Injury, Lung Injury
Lung and Diaphragm-Protective Ventilation by Means of Assessing Respiratory Work
This study is designed to test a proposed strategy for lung- and diaphragm-protective ventilation (LDPV) in patients with acute hypoxemic respiratory failure.
- Conditions
- Diaphragm Injury, Lung Injury, Respiratory Insufficiency, Mechanical Ventilation Complication
- Trial name
- LANDMARK (NCT03612583)
- Testing
- Lung- and Diaphragm-Protective Ventilation
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- University Health Network, Toronto
Respiratory Distress Syndrome, Adult
A Validation/Interventional Study on Stress Index in Predicting Mechanical Stress in ARDS Patients
30% of ARDS patients ventilated according to NIH protocol presents CT scan evidence of hyperinflation. Functional analysis of pressure-time curve (Stress Index=SI) has been shown to identify this condition in experimental…
- Trial name
- NCT00465374
- Testing
- Change ventilatory parameters with stress index monitoring
- Where
- Italy
- Sponsor
- University of Turin, Italy
HIV Infections
A Pilot Study for Toxicity Evaluation of HIV Rectal Microbicides
The purpose of this study is to determine if detectable changes in permeability of the lining of the colon are caused by either application of HIV microbicide gels or medical procedures, such as flexible sigmoidoscopy.
- Trial name
- NCT00389311
- Testing
- Normosol-R, Nonoxynol-9, Gastrointestinal instrumentation
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Strength Training, Muscle Strength, Muscle Mass, Inflammatory Processes
The Role of Mechanical Stress and Muscle Fatigue in Strength Gains
The purpose of this study is to compare the impact of different levels of mechanical stress and muscle fatigue in strength training conditions on muscle strength, muscle mass and inflammatory processes.
- Trial name
- NCT01216774
- Testing
- Strength training
- Where
- Belgium
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Mechanical Ventilation Complication
Reduce Pediatric Sedation to Reduce Mechanical Ventilation Complication in ICU
Mechanical ventilation is a common procedure used in pediatric intensive care units (ICU). Its use requires almost always the establishment of a sedation.
- Trial name
- PEDIASED (NCT02040168)
- Where
- France
- Volunteers
- 106 people
- Sponsor
- Nantes University Hospital
Caregiver, Mindfulness
Resourcefulness Training and Decentering on Self-Management in Caregivers of Technology Dependent Children
The investigators will conduct a randomized clinical trial pilot study to examine the effectiveness of a theoretically based intervention (called ReMind) encompassing two key components: (a) Resourcefulness Training for parent…
- Conditions
- Caregiver, Mindfulness, Mechanical Ventilation Pressure High, Gastrostomy
- Trial name
- NCT02993887
- Testing
- Resourcefulness Training, Mindfulness
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Monckeberg Medial Calcific Sclerosis
Mechanical Stress Effects on the Cardiovascular Adaptations of Peripheral Arterial Calcifications Among Athletes
The main objective of this study is to obtain data for the integrated analysis of morphological, functional and biomechanical parameters pertaining to lower limb arteries in various categories of elite athletes (without…
- Trial name
- MediaSport (NCT01577576)
- Where
- 2 sites in France
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Sedative Drug Consumption, Mechanically Ventilated ICU Patients
Efficacy of Music on Reduction of Sedative Drugs in Mechanically Ventilated Intensive Care Unit Patients
Major objective: a three-days interventional cross-over trial [one day music on, one day wash-out, one day music off][two periods of listening/day], to evaluate: 1. Impact on sedative drug consumption. 2.
- Trial name
- MUSIC (NCT00880035)
- Testing
- MP3 music program listening
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Université de Sherbrooke
Forward Head Posture
Relationship of Forward Head Posture With Burnout and Quality of Life
The goal of this observational study is to investigate the relationship of forward head posture with burnout and quality of life in patients with mechanical neck pain.
- Trial name
- NCT07891260
- Testing
- postural, physical, and cognitive assessment
- Volunteers
- 50 people
- Sponsor
- Cairo University
Inflammation
Study of the Influence of Various Tidal Volumes on Exhaled Breath Condensate (EBC) in Mechanically Ventilated Patients
The aim of the present study is to evaluate the effect of low (6 ml/kg) and high (12 ml/kg) tidal volume ventilation on inflammatory and oxidative stress biomarkers in the exhaled breath condensate (EBC) of ICU patients without…
- Trial name
- TDEBC (NCT00910026)
- Testing
- low tidal volume ventilation, high tidal volume ventilation
- Where
- Greece
- Volunteers
- 20 people
- Sponsor
- Larissa University Hospital