Clinical trials: Mechanical Ventilation After Surgery
Mechanical Ventilation, Thoracic Surgery
Effects of Oxygen Supply After Lung Isolation in Thoracic Surgery
The goal of this randomized clinical trial is to compare a liberal versus restrictive oxygen supply (fraction of inspired oxygen, FiO2) strategy in patients scheduled for thoracic surgery requiring one-lung ventilation during…
- Conditions
- Mechanical Ventilation, Thoracic Surgery, One-Lung Ventilation
- Trial name
- NCT05946707
- Testing
- restrictive oxygen supply, liberal oxygen supply
- Where
- Austria
- Volunteers
- 55 people
- Sponsor
- Medical University Innsbruck
Oxycodone, Analgesia
Efficacy and Safety of Oxycodone Hydrochloride for Long-term Analgesia in ICU Patients
The goal of this clinical trial is to learn if oxycodone hydrochloride works to manage pain in patients requiring mechanical ventilation. It will also assess the safety of oxycodone hydrochloride.
- Conditions
- Oxycodone, Analgesia, Mechanical Ventilation, Postoperative
- Trial name
- NCT06444997
- Testing
- Oxycodone Hydrochloride, Remifentanil
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Zhongshan Hospital
Mechanical Ventilation
RespirAq Humidifier Usability During Invasive Ventilation
This study aims to capture preliminary safety and effectiveness information on a near-final humidifier device design and to provide data for more extensive research, if required.
- Trial name
- NCT04765878
- Testing
- RespirAq Humidification
- Volunteers
- 20 people
- Sponsor
- Auckland University of Technology
Morality, Hypothermic Circulatory Arrest Time
A Comparative Study of Different Hypothermic Circulatory Arrest Strategies on Aortic Surgery.
By comparing the clinical outcome of patients underwent different hypothermic circulatory arrest (mild hypothermic versus moderate hypothermic) during aortic arch surgery, this study aims to determine the optimal hypothermic…
- Conditions
- Morality, Hypothermic Circulatory Arrest Time, Aortic-cross Clamping Time, Cardiopulmonary Bypass Time
- Trial name
- NCT03454633
- Testing
- the temperature of hypothermic circulatory arrest
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xiaoping Fan. MD
Mechanical Ventilation Complication
Potential Impact of the Use of the Application VentilO After Cardiac Surgery
Mechanical ventilation is a vital support associated with the treatment of patients with acute respiratory failure and in other indications such as surgery under general anesthesia, coma or shock.
- Trial name
- NCT05886413
- Testing
- VentilO application
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Laval University
ICU(Intensive Care Unit) Patients, Mechanical Ventilation After Surgery
Respiratory Volume Measure Using ExSpiron 1Xi
The purpose of this study was to determine the accuracy of one-time respiratory volume measured by RVM(Respiratory Volume Monitor) compared to the one-time respiratory volume measured by mechanical ventilation in post-operative…
- Trial name
- NCT02998294
- Testing
- Respiratory Volume Monitor(RVM), artificial respirator
- Where
- South Korea
- Volunteers
- 63 people
- Sponsor
- Yonsei University
Post Operative Cardiac Surgery, ARDS
PEEP Levels Selected by PEEP Titration and PEEP Levels Routinely Used in Post-operative Cardiac Patients With Hypoxemic Respiratory Failure
The purpose of this study is to: Compare PEEP level selected by individualized PEEP titration by electrical impedance tomography and PEEP level routinely used in post-operative cardiac patients with Hypoxemic Respiratory Failure…
- Conditions
- Post Operative Cardiac Surgery, ARDS, Hypoxemic Respiratory Failure
- Trial name
- NCT02056977
- Testing
- Titration, control
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- University of Sao Paulo General Hospital
Mechanical Power, Alveolar Recruitment Maneuvers
The Role of Periodic Alveolar Recruitment Maneuvers in Intraoperative Protective Ventilation
The goal of this clinical trial is to compare three open-lung strategies on respiratory function and lung injury in protective ventilation for laparoscopic anterior resection.
- Conditions
- Mechanical Power, Alveolar Recruitment Maneuvers, Protective Ventilation, Postoperative Pulmonary Complications
- Trial name
- REMAIN-2 (NCT05962125)
- Testing
- periodic alveolar recruitment maneuvers, positive end-expiratory pressure
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Retinopathy
Anesthesia for Retinopathy of Prematurity
Premature infants experience more respiratory problems after surgical procedures. The investigators aimed to compare general anesthesia with sedation on the need for post-operative mechanical ventilation in infants undergoing…
- Trial name
- NCT01955135
- Testing
- Ketamine, Sevoflurane, propofol
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Thoracic Anesthesia, Thoracotomy Surgery
Mechanical Power in One-lung Ventilation
Thoracic surgery usually necessitates one-lung ventilation (OLV) to provide surgical access while maintaining adequate gas exchange.
- Trial name
- POWEROL (NCT07353788)
- Volunteers
- 300 people
- Sponsor
- Ankara University
NIV Intolerance
Evaluation of Remifentanil and Dexmedetomidine in Patients With Noninvasive Mechanical Ventilation Intolerance
Currently, NIV(Noninvasive ventilation ) is widely used in patients with hypoxemia and atelectasis after cardiac surgery.About 15% of patients have intolerance during NIV.
- Trial name
- NCT04734418
- Testing
- Remifentanil, Dexmedetomidine
- Where
- China
- Volunteers
- 178 people
- Sponsor
- Shanghai Zhongshan Hospital
Postoperative Pulmonary Complications, Impaired Oxygenation
PEEP Strategies and Mechanical Power in Robotic Surgery
Robotic surgery requires pneumoperitoneum and steep Trendelenburg positioning, which significantly impair respiratory mechanics and increase the risk of postoperative pulmonary complications.
- Conditions
- Postoperative Pulmonary Complications, Impaired Oxygenation, Mechanical Ventilation
- Trial name
- NCT07536464
- Testing
- Fixed PEEP Ventilation, Decremental PEEP Strategy, Incremental PEEP Strategy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Postoperative Pulmonary Complications, Mechanical Ventilation
Driving Pressure-Guided Individualized PEEP Versus Standard PEEP: Effects on Postoperative Pulmonary Complications in Upper Abdominal Digestive Surgery
This randomized clinical trial compares two methods of setting positive end-expiratory pressure (PEEP) during general anesthesia in adults undergoing upper abdominal digestive surgery who are at moderate or high risk of…
- Trial name
- NCT07885124
- Testing
- Driving Pressure-Guided Individualized PEEP, Standard PEEP
- Where
- Tunisia
- Volunteers
- 210 people
- Sponsor
- Hopital Charles Nicolle
Surgery, Anaesthesia
Local Assessment of Ventilatory Management During General Anesthesia for Surgery
Objectives 1. To characterize mechanical ventilation practices during general anesthesia for surgery 2. To assess the dependence of intra-operative and post-operative pulmonary complications on intra-operative Mechanical…
- Conditions
- Surgery, Anaesthesia, Ventilator-Induced Lung Injury, Lung Injury
- Trial name
- LAS VEGAS (NCT01601223)
- Where
- 19 sites in United States, Estonia and 6 more
- Volunteers
- 10,690 people
- Sponsor
- European Society of Anaesthesiology
Sedation, Respiration, Artificial
Dexmedetomidine for Postoperative Sedation in Patients Undergoing Repair of Thoracoabdominal Aortic Aneurysms
The primary objective of this study is to test the hypothesis that time on the ventilator and ICU length of stay will be shorter in TAA patients given postoperative sedation with dexmedetomidine compared to those given standard…
- Conditions
- Sedation, Respiration, Artificial, Length of Stay
- Trial name
- NCT00409344
- Testing
- Dexmedetomidine, Normal Saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Upper Abdominal Surgery, Critical Ill Patients in SICU
Non-Invasive Respiratory Monitoring to Predict Successful Separation From Mechanical Ventilation Following Upper Abdominal Surgery
The VALUE Study is a two-phase, prospective clinical trial conducted at King Chulalongkorn Memorial Hospital (KCMH). The study evaluates the prevalence of mechanical ventilation (MV) separation failure in post-open upper…
- Trial name
- VALUE (NCT07678502)
- Testing
- High Flow Oxygen, Nasal canula oxygen
- Volunteers
- 40 people
- Sponsor
- Papawee Chennavasin
Robotic Surgery, Post Operative Pulmonary Complications
Low-Intensity Mechanical Ventilation in the Operating Room: a Pilot Study
The aim of the study is to assess whether a bundle of protective low-intensity mechanical ventilation interventions reduces perioperative atelectasis and postoperative pulmonary complications, compared with standard care in a…
- Trial name
- VIOLET (NCT07277244)
- Testing
- Low Intensity Mechanical Ventilation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Beth Israel Deaconess Medical Center
Intensive Care (ICU)
Role of Lung Ultrasound in Weaning From Mechanical Ventilation in Postoperative Neurosurgical ICU Patients
The aim of this study is to demonstrate the role of lung ultrasound in weaning from mechanical ventilation in neurosurgical ICU patients compared to the ordinary tools as chest X-ray , ABG, rapid shallow breathing index…
- Trial name
- NCT03921112
- Testing
- lung ultrasound, routine tools
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Ain Shams University
Analgesic, Sedative
Analgesic and Sedative Effect of Fentanyl Versus Dexmedetomidine Infusion in Post-Operative Mechanically Ventilated Children After Open Abdominal Surgeries
This study aimed to compare the efficacy and safety of fentanyl versus dexmedetomidine infusion in this population.
- Conditions
- Analgesic, Sedative, Fentanyl, Dexmedetomidine
- Trial name
- NCT06994273
- Testing
- Fentanyl, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Tanta University
Postoperative Respiratory Failure, Abdominal Surgery
Mechanical Power for Ventilatory Settings in Operating Room
Postoperative respiratory failure (PRF) is a dreaded complication that imposes a significant burden through unplanned admission to the ICU, post discharge disability and mortality.
- Conditions
- Postoperative Respiratory Failure, Abdominal Surgery, Postoperative Pulmonary Complications, Morality
- Trial name
- IMPROVEIII (NCT07620132)
- Testing
- Mechanical power-guided ventilatory strategy, Standard fixed ventilatory settings
- Volunteers
- 490 people
- Sponsor
- University Hospital, Montpellier